Aliases for LGALS8 Gene
External Ids for LGALS8 Gene
Previous GeneCards Identifiers for LGALS8 Gene
This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for LGALS8 Gene
LGALS8 (Lectin, Galactoside-Binding, Soluble, 8) is a Protein Coding gene. Diseases associated with LGALS8 include cholesteatoma and laryngeal benign neoplasm. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is LGALS9B.
UniProtKB/Swiss-Prot for LGALS8 Gene
Lectin with a marked preference for 3-O-sialylated and 3-O-sulfated glycans.