Aliases for LGALS8 Gene
External Ids for LGALS8 Gene
Previous GeneCards Identifiers for LGALS8 Gene
This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for LGALS8 Gene
LGALS8 (Lectin, Galactoside Binding Soluble 8) is a Protein Coding gene. Diseases associated with LGALS8 include prostatic hypertrophy and cholesteatoma. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is LGALS9B.
UniProtKB/Swiss-Prot for LGALS8 Gene
Lectin with a marked preference for 3-O-sialylated and 3-O-sulfated glycans.