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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

LGALS7 Gene

protein-coding GIFtS: 56
GCID: GC19M039261

lectin, galactoside-binding, soluble, 7

Explore 22 diseases affiliated with
LGALS7 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Lectin, Galactoside-Binding, Soluble, 7¹ ²		Galectin-7¹
GAL7¹ ²		Gal-7³
LGALS7A¹ ²		HKL-14³
PIG1¹ ³		PI7³
TP53I1¹		P53-Induced Gene 1 Protein³
Galectin 7²

External Ids:	HGNC: 6568¹	Entrez Gene: 3963²	Ensembl: ENSG00000205076⁷	OMIM: 600615⁵	UniProtKB: P47929³

Export aliases for LGALS7 gene to outside databases

Previous GC identifers: GC19P039892 GC19P039671 GC19P043955 GC19P043971 GC19P043939 GC19M043954 GC19P035727

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for LGALS7:

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix

interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in

keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is

found adjacent to, but on the opposite strand on chromosome 19. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: LEG7_HUMAN, P47929

Function: Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control.

Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release

Gene Wiki entry for LGALS7

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000019.9 NT_011109.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the LGALS7 gene promoter:
CREB NF-1 p53 HSF2 deltaCREB HSF1 (long) Arnt
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: LGALS7 promoter sequence

Search SABiosciences Chromatin IP Primers for LGALS7

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LGALS7

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.2 Ensembl cytogenetic band: 19q13.2 HGNC cytogenetic band: 19q13.13

LGALS7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LGALS7 gene location

GeneLoc information about chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19M039261: view genomic region (about GC identifiers)

Start:	39,261,608 bp from pter	End:	39,264,157 bp from pter
Size:	2,550 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: LEG7_HUMAN, P47929 (See protein sequence)

Recommended Name: Galectin-7

Size: 136 amino acids; 15075 Da

Subunit: Monomer

Subcellular location: Cytoplasm. Nucleus. Secreted (Potential). Note=May be secreted by a non-classical secretory

pathway

6/7 PDB 3D structures from and Proteopedia for LGALS7 (see all 7):

1BKZ (3D)

2GAL (3D)

3GAL (3D)

3ZXE (3D)

3ZXF (3D)

4GAL (3D)

Secondary accessions: Q6IB87

Explore the universe of human proteins at neXtProt for LGALS7: NX_P47929

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P47929

LGALS7 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_002298.1

ENSEMBL proteins:

ENSP00000367891

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	ProSpec Recombinant Protein for LGALS7
	Uscn Proteins for LGALS7

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005615	extracellular space	--	--
GO:0005634	nucleus	--	--
GO:0005737	cytoplasm	--	--

LGALS7 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for LGALS7

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

LGALS7 for domains About GeneDecksing

3 InterPro domains/families:

IPR001079 Galectin_CRD

IPR013320 ConA-like_subgrp

IPR008985 ConA-like_lec_gl_sf

Graphical View of Domain Structure for InterPro Entry P47929

ProtoNet protein and cluster: P47929

1 Blocks protein family: IPB001079 Galectin

UniProtKB/Swiss-Prot: LEG7_HUMAN, P47929

Similarity: Contains 1 galectin domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: LEG7_HUMAN, P47929

Function: Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control.

Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release

Induction: By p53/TP53

Genatlas biochemistry entry for LGALS7:

lectin,galactoside-beta binding,soluble 7

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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Gene Editing
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In Situ Assay
Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for LGALS7

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0030246	carbohydrate binding	--	--

LGALS7 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for LGALS7

STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

5/15 Interacting proteins for LGALS7 (P47929^{2, 3} ENSP00000367891⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 15)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CA12	O43570²^,³, ENSP00000178638⁴	MINT-63767 I2D: score=4 STRING: ENSP00000178638
MAP3K3	Q99759²^,³	MINT-48509 I2D: score=2
WIPI1	Q5MNZ9³, ENSP00000262139⁴	I2D: score=3 STRING: ENSP00000262139
USP1	O94782³, ENSP00000343526⁴	I2D: score=2 STRING: ENSP00000343526
MYC	P01106³, ENSP00000367207⁴	I2D: score=1 STRING: ENSP00000367207

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006915	apoptotic process	--	--
GO:0007157	heterophilic cell-cell adhesion	--	--

LGALS7 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

LGALS7 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for LGALS7

2 DrugBank Compounds for LGALS7 About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
2-Deoxy-2-Aminogalactose	--	--	target	--	17139284 17016423
Beta-D-Glucose	--	50-99-7	target	--	17139284 17016423

5 Novoseek chemical compound relationships for LGALS7 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
n-acetyllactosamine	68.4	2	9760227 (1), 16242339 (1)
galactose	42.8	6	9760227 (1), 18421797 (1), 18080343 (1), 15902270 (1)
lactose	39.5	6	9760227 (1), 17631664 (1), 7534301 (1), 15958565 (1)
carbohydrates	9.19	2	9760227 (1), 14758069 (1)
retinoic acid	4.57	2	7729568 (2)

Search CenterWatch for drugs/clinical trials and news about LGALS7 / LEG7

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for LGALS7 gene:

NM_002307.3

Unigene Cluster for LGALS7:

Lectin, galactoside-binding, soluble, 7

Hs.702546 [show with all ESTs]

Unigene Representative Sequence: BM913998

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000378626(uc002oje.3)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LGALS7
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		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for LGALS7 (see all 7) OriGene shRNA RFP: LGALS7 OriGene siRNA: LGALS7
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LGALS7

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		GenScript: all cDNA clones in your preferred vector: LGALS7 (NM_002307)
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LGALS7
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LGALS7

Additional cDNA sequence: CR456917.1

3 DOTS entries:

DT.97805209 DT.315778 DT.121497722

24/56 AceView cDNA sequences (see all 56):

CN478604 AI826905 AW015224 AI202604 AI420402 L07769 AI659838 AW516753

AI094346 BF197794 AI417987 AI201871 BC042911 AA689478 BM020432 AI969775

BC073743 AI143778 CR456917 BV197147 BC061588 BG211253 AI123909 BV167644

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

LGALS7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

LGALS7 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Lung

Respiratory Bronchioles

Lung

Testis

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See LGALS7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for LGALS7

SOURCE GeneReport for Unigene cluster: Hs.702546

UniProtKB/Swiss-Prot: LEG7_HUMAN, P47929

Tissue specificity: Mainly expressed in stratified squamous epithelium

SABiosciences Custom PCR Arrays for LGALS7

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LGALS7 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LGALS7

In Situ
Assay Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for LGALS7

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for LGALS7 gene from 3/14 species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	--	--	33(a)	1 → many	GL343281.1(925666-928230)
fruit fly (Drosophila melanogaster)	Insecta	galectin⁶ CG11374⁶	--	8(a) 7(a)	possible ortholog possible ortholog	2L(71757-76211) 2L(76348-77783)
worm (Caenorhabditis elegans)	Secernentea	lec-2⁶ lec-1⁶ (see all 6)	32 kDa beta-galactoside-binding lectin (see all 6)	4(a) 17(a) (see all 6)	many ↔ many many ↔ many (see all 6)	II(10009547-10016001) II(13195479-13199533)

ENSEMBL Gene Tree for LGALS7 (if available)
TreeFam Gene Tree for LGALS7 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for LGALS7 gene

LGALS7B¹ ² LGALS8² LGALS3² LGALS9² LGALS9C² LGALSL² LGALS4² LGALS12²

LGALS9B²

14 SIMAP similar genes for LGALS7 using alignment to 2 protein entries: LEG7_HUMAN (see all proteins):

LGALS9 LGALS3 LGALS9C LGALS12 LGALS8 GRIP1

LGALS9B LGALS2 LGALS1 LGALS14 LGALS16 LGALS13

LGALS10A CLC

LGALS7 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs79770156^1,2	F,	--	35725405(-)	`CTCGCC/TTGGGC`	1	--	us2k¹		1		NA	120
rs78603808^1,2	F,	--	35725913(-)	`GCCCTC/TCTGGA`	1	--	us2k¹		1		WA	118
rs74428609^1,2	F,	--	35726741(-)	`TGAGAA/TCCTCC`	1	--	us2k¹		1		WA	118
rs78939874^1,2	F,	--	35726796(-)	`ATATTA/GGGTCC`	1	--	us2k¹		1		WA	118
rs187728017^1,2		--	39262622(+)	`TGCAGC/GGCGGC`	2	A	syn¹		0	--	--	--	--
rs201209491^1,2	C,F	--	39262681(+)	`AGAGGA/GGGATG`	1	--	int¹		1		EU	102
rs145035521^1,2	C,	--	39263027(+)	`ACACCA/GCAGAA`	1	--	int¹		0	--	--	--	--
rs200874288^1,2		--	39263706(+)	`CAGGGA/CGGATG`	2	R L	mis¹		0	--	--	--	--
rs3786852^1,2	C,F,	--	39264271(-)	`GCTTGC/ACCCAG`	1	--	us2k¹		1		EA	1492
rs138945880^1,2		--	39264333(+)	`CCCAGA/GGCCCG`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for LGALS7 (39261608 - 39264157 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for LGALS7
1 Indel: 33325
1 Inversion: 37203

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LGALS7

DNA2.0 Custom Variant and Variant Library Synthesis for LGALS7

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

LGALS7 for disorders           About GeneDecksing

OMIM gene information: 600615    OMIM disorders: --

20/22 diseases for LGALS7 (see all 22):    About MalaCards

squamous cell carcinoma laryngeal squamous cell carcinoma bladder squamous cell carcinoma pyelonephritis

esophageal squamous cell carcinoma gastric papillary adenocarcinoma acute pyelonephritis bacteriuria

newcastle disease basal cell carcinoma ovarian cyst laryngitis

carcinoma cervical carcinoma pneumonia esophagitis

cervicitis influenza adenocarcinoma breast cancer

2 diseases from the University of Copenhagen DISEASES database for LGALS7:

Influenza Cancer

8 Novoseek disease relationships for LGALS7 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
carcinoma squamous cell	38.9	4	10500176 (1), 19012243 (1), 11706006 (1), 16315769 (1)
carcinoma	23.1	6	18315601 (1), 16315769 (1), 17283157 (1), 9697310 (1) (see all 5)
colon carcinoma	21.1	2	11706006 (1), 15313906 (1)
cancer	19.9	13	17283157 (3), 16429325 (1), 13679866 (1), 18418527 (1) (see all 10)
lymphoma	18.6	15	15958565 (4), 19596268 (3), 17363605 (2), 19012243 (1) (see all 5)
metastasis	11.7	5	20382700 (4), 16197887 (1)
shock	8.25	2	17330866 (1), 19507834 (1)
tumors	6.47	13	15313906 (3), 9307301 (2), 17363605 (2), 10500176 (1) (see all 7)

Export disorders for LGALS7 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for LGALS7 gene, integrated from 9 sources (see all 84):
(articles sorted by number of sources associating them with LGALS7)

Utopia: connect your pdf to the dynamic
world of online information

Cloning, expression, and chromosome mapping of human galectin-7. (PubMed id 7534301)^{1, 2, 3, 9} Madsen P.... Celis J.E. (1995)
Galectin-7, a human 14-kDa S-lectin, specifically expressed in keratinocytes and sensitive to retinoic acid. (PubMed id 7729568)^{1, 2, 3, 9} Magnaldo T....Darmon M. (1995)
Galectin-7 (PIG1) exhibits pro-apoptotic function through JNK activation and mitochondrial cytochrome c release. (PubMed id 11706006)^{1, 2, 9} Kuwabara I.... Liu F.T. (2002)
Structural basis for the recognition of carbohydrates by human galectin-7. (PubMed id 9760227)^{1, 2, 9} Leonidas D.D....Acharya K.R. (1998)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Expression of Galectin-3 and Galectin-7 in thyroid malignancy as potential diagnostic indicators. (PubMed id 18418527)^{1, 9} Than T.H....Abdullah M.S. (2008)
Overexpression of galectin-7, a myoepithelial cell ma rker, enhances spontaneous metastasis of breast cancer cells. (PubMed id 20382700)^{1, 9} Demers M....St-Pierre Y. (2010)
Galectin-7: will the lectin's activity establish clinical correlations in head and neck squamous cell and basal cell carcinomas? (PubMed id 19012243)^{1, 9} Cada Z....Gabius H.J. (2009)
Induction of matrix metalloproteinase-9 by galectin-7 through p38 MAPK signaling in HeLa human cervical epithelial adenocarcinoma ce lls. (PubMed id 19885589)^{1, 9} Park J.E....Cho M. (2009)
Galectin-7, a marker of all types of stratified epithelia. (PubMed id 9697310)^{1, 9} Magnaldo T....Darmon M. (1998)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 3963	HGNC: 6568	AceView: LGALS7	Ensembl:ENSG00000205076	euGenes: HUgn3963
ECgene: LGALS7	H-InvDB: LGALS7

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for LGALS7	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for LGALS7	Genetics and Cytogenetics in Oncology and Haematology
Functional Glycomics Gateway - Glycan Binding	http://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Stlect_00143

Intellectual Property for LGALS7 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for LGALS7 gene:
Search GeneIP for patents involving LGALS7

Licensable Technologies for LGALS7 gene:

Tufts University:

Use of Galectins to treat dry eye syndrome

(see all 2)

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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ThermoFisher Antibodies for LGALS7

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GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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lectin, galactoside-binding, soluble, 7

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LGALS7 Gene

lectin, galactoside-binding, soluble, 7

Aliasesfor LGALS7 gene

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Protein Domains /Familiesfor LGALS7 gene

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for LGALS7 gene

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for LGALS7 gene

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for LGALS7 gene

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