Aliases for LGALS1 Gene
External Ids for LGALS1 Gene
Previous GeneCards Identifiers for LGALS1 Gene
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation. [provided by RefSeq, Jul 2008]
GeneCards Summary for LGALS1 Gene
LGALS1 (Lectin, Galactoside-Binding, Soluble, 1) is a Protein Coding gene. Diseases associated with LGALS1 include benign metastasizing leiomyoma and echolalia. Among its related pathways are NF-kappaB Signaling and MAP Kinase Signaling. GO annotations related to this gene include poly(A) RNA binding and signal transducer activity. An important paralog of this gene is LGALS2.
UniProtKB/Swiss-Prot for LGALS1 Gene
May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.