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Aliases for LEUTX Gene

Aliases for LEUTX Gene

  • Leucine Twenty Homeobox 2 3 5

External Ids for LEUTX Gene

Previous GeneCards Identifiers for LEUTX Gene

  • GC19P044961
  • GC19P040267
  • GC19P036713

Summaries for LEUTX Gene

GeneCards Summary for LEUTX Gene

LEUTX (Leucine Twenty Homeobox) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LEUTX Gene

Genomics for LEUTX Gene

Regulatory Elements for LEUTX Gene

Transcription factor binding sites by QIAGEN in the LEUTX gene promoter:

Genomic Location for LEUTX Gene

Chromosome:
19
Start:
39,776,594 bp from pter
End:
39,786,135 bp from pter
Size:
9,542 bases
Orientation:
Plus strand

Genomic View for LEUTX Gene

Genes around LEUTX on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LEUTX Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LEUTX Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LEUTX Gene

Proteins for LEUTX Gene

  • Protein details for LEUTX Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MZ59-LEUTX_HUMAN
    Recommended name:
    Leucine-twenty homeobox
    Protein Accession:
    A8MZ59

    Protein attributes for LEUTX Gene

    Size:
    168 amino acids
    Molecular mass:
    18626 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LEUTX Gene

Proteomics data for LEUTX Gene at MOPED

Post-translational modifications for LEUTX Gene

No Post-translational modifications

Other Protein References for LEUTX Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for LEUTX Gene

Domains & Families for LEUTX Gene

Gene Families for LEUTX Gene

Protein Domains for LEUTX Gene

Suggested Antigen Peptide Sequences for LEUTX Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A8MZ59

UniProtKB/Swiss-Prot:

LEUTX_HUMAN :
  • Contains 1 homeobox DNA-binding domain.
  • Belongs to the paired homeobox family.
Domain:
  • Contains 1 homeobox DNA-binding domain.
Family:
  • Belongs to the paired homeobox family.
genes like me logo Genes that share domains with LEUTX: view

Function for LEUTX Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LEUTX Gene

Localization for LEUTX Gene

Subcellular locations from UniProtKB/Swiss-Prot for LEUTX Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for LEUTX Gene COMPARTMENTS Subcellular localization image for LEUTX gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for LEUTX Gene

Pathways & Interactions for LEUTX Gene

SuperPathways for LEUTX Gene

No Data Available

Interacting Proteins for LEUTX Gene

Gene Ontology (GO) - Biological Process for LEUTX Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LEUTX Gene

Drugs & Compounds for LEUTX Gene

No Compound Related Data Available

Transcripts for LEUTX Gene

mRNA/cDNA for LEUTX Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for LEUTX Gene

Leucine twenty homeobox:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for LEUTX Gene

No ASD Table

Relevant External Links for LEUTX Gene

GeneLoc Exon Structure for
LEUTX
ECgene alternative splicing isoforms for
LEUTX

Expression for LEUTX Gene

mRNA expression in normal human tissues for LEUTX Gene

SOURCE GeneReport for Unigene cluster for LEUTX Gene Hs.451638

genes like me logo Genes that share expression patterns with LEUTX: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for LEUTX Gene

Orthologs for LEUTX Gene

This gene was present in the common ancestor of mammals.

Orthologs for LEUTX Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LEUTX 35
  • 99.4 (n)
  • 98.81 (a)
LEUTX 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LEUTX 36
  • 37 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LEUTX 36
  • 46 (a)
OneToOne
Species with no ortholog for LEUTX:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for LEUTX Gene

ENSEMBL:
Gene Tree for LEUTX (if available)
TreeFam:
Gene Tree for LEUTX (if available)

Paralogs for LEUTX Gene

Pseudogenes.org Pseudogenes for LEUTX Gene

genes like me logo Genes that share paralogs with LEUTX: view

No data available for Paralogs for LEUTX Gene

Variants for LEUTX Gene

Sequence variations from dbSNP and Humsavar for LEUTX Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs719109 -- 39,779,295(-) cctta(A/G)gcaac intron-variant
rs719110 -- 39,779,178(-) gccta(A/G)gagct intron-variant
rs998973 -- 39,782,682(+) CCCAT(C/T)TGTGG intron-variant
rs1155506 -- 39,776,071(+) TGTGC(A/C/G)ACTTA upstream-variant-2KB
rs2108687 -- 39,784,269(+) ATCAC(A/G)GATTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LEUTX Gene

Variant ID Type Subtype PubMed ID
dgv1082e1 CNV Complex 17122850

Variation tolerance for LEUTX Gene

Gene Damage Index Score: 0.35; 7.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for LEUTX Gene

HapMap Linkage Disequilibrium report
LEUTX

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LEUTX Gene

Disorders for LEUTX Gene

Relevant External Links for LEUTX

Genetic Association Database (GAD)
LEUTX
Human Genome Epidemiology (HuGE) Navigator
LEUTX
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
LEUTX

No disorders were found for LEUTX Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LEUTX Gene

Publications for LEUTX Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48 67
  2. Classification and nomenclature of all human homeobox genes. (PMID: 17963489) Holland P.W.H. … Bruford E.A. (BMC Biol. 2007) 3
  3. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3

Products for LEUTX Gene

Sources for LEUTX Gene

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