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Aliases for LENG1 Gene

Aliases for LENG1 Gene

  • Leukocyte Receptor Cluster (LRC) Member 1 2 3

External Ids for LENG1 Gene

Previous GeneCards Identifiers for LENG1 Gene

  • GC19M055305
  • GC19M055084
  • GC19M059335
  • GC19M059351
  • GC19M054658
  • GC19M050976

Summaries for LENG1 Gene

GeneCards Summary for LENG1 Gene

LENG1 (Leukocyte Receptor Cluster (LRC) Member 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LENG1 Gene

Genomics for LENG1 Gene

Regulatory Elements for LENG1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for LENG1 Gene

54,155,161 bp from pter
54,159,882 bp from pter
4,722 bases
Minus strand

Genomic View for LENG1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for LENG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LENG1 Gene

Proteins for LENG1 Gene

  • Protein details for LENG1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Leukocyte receptor cluster member 1
    Protein Accession:
    Secondary Accessions:
    • Q9HCU7

    Protein attributes for LENG1 Gene

    264 amino acids
    Molecular mass:
    30529 Da
    Quaternary structure:
    No Data Available
    • Belongs to the leukocyte receptor cluster (LRC) present on 19q13.4
    • Sequence=AAG01393.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for LENG1 Gene

Proteomics data for LENG1 Gene at MOPED

Post-translational modifications for LENG1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for LENG1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for LENG1 Gene

Domains for LENG1 Gene

Protein Domains for LENG1 Gene


Suggested Antigen Peptide Sequences for LENG1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LENG1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for LENG1 Gene

Function for LENG1 Gene

Gene Ontology (GO) - Molecular Function for LENG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with LENG1: view

Phenotypes for LENG1 Gene

GenomeRNAi human phenotypes for LENG1:
genes like me logo Genes that share phenotypes with LENG1: view

Animal Model Products

miRNA for LENG1 Gene

miRTarBase miRNAs that target LENG1

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for LENG1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for LENG1 Gene

Localization for LENG1 Gene

Subcellular locations from

Jensen Localization Image for LENG1 Gene COMPARTMENTS Subcellular localization image for LENG1 gene
Compartment Confidence
nucleus 3
cytosol 1
extracellular 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for LENG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with LENG1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for LENG1 Gene

Pathways for LENG1 Gene

SuperPathways for LENG1 Gene

No Data Available

Interacting Proteins for LENG1 Gene

Gene Ontology (GO) - Biological Process for LENG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with LENG1: view

No data available for Pathways by source for LENG1 Gene

Transcripts for LENG1 Gene

mRNA/cDNA for LENG1 Gene

(22) Selected AceView cDNA sequences:
(2) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for LENG1 Gene

Leukocyte receptor cluster (LRC) member 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for LENG1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for LENG1 Gene

No ASD Table

Relevant External Links for LENG1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for LENG1 Gene

mRNA expression in normal human tissues for LENG1 Gene

Protein differential expression in normal tissues for LENG1 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (16.8), Testis (12.3), CD8 Tcells (11.5), and Blymphocyte (6.1).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for LENG1 Gene

SOURCE GeneReport for Unigene cluster for LENG1 Gene Hs.590974

genes like me logo Genes that share expressions with LENG1: view

Expression partners for LENG1 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for LENG1 Gene

Orthologs for LENG1 Gene

This gene was present in the common ancestor of animals.

Orthologs for LENG1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LENG1 35
  • 85.82 (n)
  • 86.21 (a)
LENG1 36
  • 85 (a)
(Canis familiaris)
Mammalia LENG1 35
  • 84.48 (n)
  • 82.06 (a)
LENG1 36
  • 77 (a)
(Mus musculus)
Mammalia Leng1 35
  • 81.41 (n)
  • 81.92 (a)
Leng1 16
Leng1 36
  • 82 (a)
(Pan troglodytes)
Mammalia LENG1 35
  • 98.86 (n)
  • 97.35 (a)
LENG1 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Leng1 35
  • 82.18 (n)
  • 84.23 (a)
(Monodelphis domestica)
Mammalia LENG1 36
  • 66 (a)
(Anolis carolinensis)
Reptilia LENG1 36
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia leng1 35
  • 61.61 (n)
  • 65.16 (a)
Str.18286 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.22904 35
(Danio rerio)
Actinopterygii leng1 35
  • 54.78 (n)
  • 50.41 (a)
leng1 36
  • 42 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG12818 35
  • 48.27 (n)
  • 43.57 (a)
CG12818 36
  • 35 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 46 (a)
Species with no ortholog for LENG1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for LENG1 Gene

Gene Tree for LENG1 (if available)
Gene Tree for LENG1 (if available)

Paralogs for LENG1 Gene Pseudogenes for LENG1 Gene

genes like me logo Genes that share paralogs with LENG1: view

No data available for Paralogs for LENG1 Gene

Variants for LENG1 Gene

Sequence variations from dbSNP and Humsavar for LENG1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs36658 -- 54,157,845(-) AGGGA(A/G)GCTGA intron-variant
rs4806719 -- 54,157,821(+) cctgg(A/G)tcaag intron-variant
rs35034412 -- 54,156,433(+) CTAAG(A/G)AAGTT intron-variant
rs35089861 - 54,158,305(+) TTCCT(C/T)GTACT reference, missense
rs35147997 -- 54,157,181(+) AAGCT(-/C)CCCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LENG1 Gene

Variant ID Type Subtype PubMed ID
esv2718812 CNV Deletion 23290073
dgv4001n71 CNV Loss 21882294
nsv515623 CNV Loss 19592680
dgv4002n71 CNV Loss 21882294
nsv912398 CNV Loss 21882294
nsv510774 CNV Loss 20534489
nsv9751 CNV Gain 18304495

Relevant External Links for LENG1 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LENG1 Gene

Disorders for LENG1 Gene

No disorders were found for LENG1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for LENG1 Gene

Publications for LENG1 Gene

  1. Extensive gene duplications and a large inversion characterize the human leukocyte receptor cluster. (PMID: 10941842) Wende H. … Ziegler A. (Immunogenetics 2000) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  5. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 3

Products for LENG1 Gene

Sources for LENG1 Gene

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