Aliases for LEFTY1 Gene
External Ids for LEFTY1 Gene
Previous HGNC Symbols for LEFTY1 Gene
Previous GeneCards Identifiers for LEFTY1 Gene
This gene encodes a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Jul 2008]
GeneCards Summary for LEFTY1 Gene
LEFTY1 (Left-Right Determination Factor 1) is a Protein Coding gene. Diseases associated with LEFTY1 include visceral heterotaxy. Among its related pathways are Integrated Pancreatic Cancer Pathway and Apoptotic Pathways in Synovial Fibroblasts. GO annotations related to this gene include cytokine activity and transforming growth factor beta receptor binding. An important paralog of this gene is LEFTY2.
UniProtKB/Swiss-Prot for LEFTY1 Gene
Required for left-right axis determination as a regulator of LEFTY2 and NODAL.