LDOC1L Gene
protein-coding GIFtS: 43
GCID: GC22M044888
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leucine zipper, down-regulated in cancer 1-like
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Aliases
for LDOC1L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Leucine Zipper, Down-Regulated In Cancer 1-Like1 2 | | Mammalian Retrotransposon-Derived Protein 62 3 | | Mar61 2 | | DKFZp761O171211 | | Mart61 2 | | Protein LDOC1L2 | | DJ1033E15.21 | | MAR63 | | Leucine Zipper Protein Down-Regulated In Cancer Cells-Like2 3 | | MART63 |
Export aliases for LDOC1L gene to outside databasesPrevious GC identifers: GC22M043168 GC22M043208 GC22M043267 GC22M027837 |
Summaries
for LDOC1L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for LDOC1L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the LDOC1L gene promoter:
NF-1 Tal-1 CUTL1 Tal-1beta E47 NRF-2 COMP1 STAT3 ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for LDOC1L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LDOC1L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q13.31 Ensembl cytogenetic band: 22q13.31 HGNC cytogenetic band: 22q13.3LDOC1L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22M044888: view genomic region
(about GC identifiers)
Start:
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44,888,450 bp from pter |
End:
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44,894,178 bp from pter |
Size:
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5,729 bases |
Orientation:
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minus strand |
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Proteins
for LDOC1L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: LDOCL_HUMAN, Q6ICC9 (See
protein sequence)Recommended Name: Protein LDOC1L Size: 239 amino acids; 26154 Da
Secondary accessions: Q6ZTR1Explore the universe of human proteins at neXtProt for LDOC1L: NX_Q6ICC9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6ICC9
LDOC1L Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_115663.2
ENSEMBL proteins: ENSP00000340434
Human Recombinant Protein Products:
LDOC1L Antibody Products:
Assay Products for LDOC1L: |
Protein
Domains /
Families
for LDOC1L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q6ICC9 UniProtKB/Swiss-Prot: LDOCL_HUMAN, Q6ICC9Similarity: Belongs to the LDOC1 family |
Function
for LDOC1L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LDOC1L (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LDOC1L (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: LDOC1L (NM_032287) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for LDOC1L | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LDOC1L |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LDOC1L |
1 GenomeRNAi human phenotype for LDOC1L:
|
Pathways & Interactions
for LDOC1L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for LDOC1L
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
3 Interacting proteins for LDOC1L (Q6ICC93 ENSP000003404344) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for LDOC1L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for LDOC1L
Search CenterWatch for drugs/clinical trials and news about LDOC1L / LDOCL
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Transcripts
for LDOC1L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for LDOC1L gene: NM_032287.2 Unigene Cluster for LDOC1L: Leucine zipper, down-regulated in cancer 1-like Hs.332795 [show with all ESTs]Unigene Representative Sequence: NM_0322871 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000341255(uc003beu.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LDOC1L (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LDOC1L (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: LDOC1L (NM_032287) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for LDOC1L | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LDOC1L |
Additional cDNA sequence: AK126304.1 AK296479.1 AK313688.1 AL136553.1 BC018713.1 BC030232.1 BX648506.1 CR456439.1 4 DOTS entries: DT.456422 DT.120666821 DT.99972784 DT.100773505 24/87 AceView cDNA sequences (see all 87): BX648506 AL120165 BX109814 BQ441201 BM462461 AA297593 BC018713 AK126304 BM460041 NM_032287 BU189841 BC030232 BU178548 CR456439 CF127138 BU624435 BU584565 AW081506 BE253467 CB265959 AA482326 BQ920833 BF526963 BF116206
GeneLoc Exon Structure
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Expression
for LDOC1L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| LDOC1L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGAGCGATT
About this image
See LDOC1L Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for LDOC1L
SOURCE GeneReport for Unigene cluster: Hs.332795
SABiosciences Custom PCR Arrays for LDOC1L
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LDOC1L
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat LDOC1L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LDOC1L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LDOC1L | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LDOC1L |
Orthologs
for LDOC1L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for LDOC1L (if available)
TreeFam Gene Tree for LDOC1L (if available) |
Paralogs
for LDOC1L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for LDOC1L gene
- RGAG42 FAM127C2 FAM127B2 LDOC12 FAM127A2
1 SIMAP similar gene for LDOC1L using alignment to 1 protein entry: LDOCL_HUMAN:LDOC1
LDOC1L for paralogs About GeneDecksing
|
Genomic Variants
for LDOC1L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for LDOC1L (44888450 - 44894178 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for LDOC1L: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LDOC1L |
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Disorders
/ Diseases
for LDOC1L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
LDOC1L for disorders About GeneDecksing
1  disease for LDOC1L: About MalaCardshypergammaglobulinemia
Export disorders for LDOC1L gene to outside databases
|
Publications
for LDOC1L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for LDOC1L gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with LDOC1L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes. (PubMed id 16093683)1, 3 Brandt J....Volff J.N. (2005)
- Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals. (PubMed id 15716091)1, 3 Brandt J.... Volff J.-N. (2005)
- A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
- Network organization of the human autophagy system. (PubMed id 20562859)1 Behrends C....Harper J.W. (2010)
- The protein network surrounding the human telomere re peat binding factors TRF1, TRF2, and POT1. (PubMed id 20811636)1 Giannone R.J....Liu Y. (2010)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1 Wiemann S.... Poustka A. (2001)
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External Searches for LDOC1L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing LDOC1L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing LDOC1L gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing LDOC1L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
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About This Section
| Patent Information for LDOC1L gene:
Search GeneIP for patents involving LDOC1L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for LDOC1L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for LDOC1L | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for LDOC1L | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LDOC1L | | | OriGene Protein Over-expression Lysate for LDOC1L | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for LDOC1L | | OriGene 3'-UTR Clone for LDOC1L | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LDOC1L | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LDOC1L | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for LDOC1L | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for LDOC1L | | OriGene Custom Protein Services for LDOC1L | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat LDOC1L | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LDOC1L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LDOC1L | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LDOC1L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LDOC1L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LDOC1L |
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 |  |  |  | |
| | | | Search Tocris compounds for LDOC1L |
| |  |  |  |  | | | | | | Recombinant Protein for LDOC1L |
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 | | | LDOC1L Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LDOC1L |
|  |  |  | | | | Search ThermoFisher Antibodies for LDOC1L |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LDOC1L |
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