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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

LDLRAD3 Gene

protein-coding   GIFtS: 43
GCID: GC11P035923

Low Density Lipoprotein Receptor Class A Domain Containing...

  Search for LDLRAD3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Low Density Lipoprotein Receptor Class A Domain Containing 31 2
LRAD32
Low-Density Lipoprotein Receptor Class A Domain-Containing Protein 32

External Ids:    HGNC: 270461   Entrez Gene: 1434582   Ensembl: ENSG000001792417   UniProtKB: Q86YD53   

Export aliases for LDLRAD3 gene to outside databases

Previous GC identifer: GC11P035664


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for LDLRAD3 Gene: 
LDLRAD3 (low density lipoprotein receptor class A domain containing 3) is a protein-coding gene. GO annotations related to this gene include beta-amyloid binding. An important paralog of this gene is LRP12.

UniProtKB/Swiss-Prot: LRAD3_HUMAN, Q86YD5
Function: May influence APP processing, resulting in a decrease in sAPP-alpha production and increased
amyloidogenic P3 peptide production (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_009237.18  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the LDLRAD3 gene promoter:
         ATF-2   Pax-6   CUTL1   Evi-1   HNF-1A   GATA-1   IRF-2   HNF-1   FOXO1a   FOXO1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for LDLRAD3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LDLRAD3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p13   Ensembl cytogenetic band:  11p13   HGNC cytogenetic band: 11p13

LDLRAD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LDLRAD3 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P035923:  view genomic region     (about GC identifiers)

Start:
35,965,531 bp from pter      End:
36,253,686 bp from pter
Size:
288,156 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: LRAD3_HUMAN, Q86YD5 (See protein sequence)
Recommended Name: Low-density lipoprotein receptor class A domain-containing protein 3 precursor  
Size: 345 amino acids; 37419 Da
Subunit: Interacts with APP precursor C-terminus (By similarity)
Subcellular location: Cell membrane; Single-pass type I membrane protein (By similarity)
Secondary accessions: B9EG81 Q8NBJ0

Explore the universe of human proteins at neXtProt for LDLRAD3: NX_Q86YD5

Explore proteomics data for LDLRAD3 at MOPED 

LDLRAD3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

LDLRAD3 Protein Expression

REFSEQ proteins: NP_777562.1  
ENSEMBL proteins: 
 ENSP00000433954   ENSP00000434313   ENSP00000318607  

Human Recombinant Protein Products for LDLRAD3: 
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OriGene Protein Over-expression Lysate for LDLRAD3
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Novus Biologicals LDLRAD3 Protein
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Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for LDLRAD3 

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005886plasma membrane IEA--
GO:0016020membrane ----
GO:0016021integral to membrane IEA--

LDLRAD3 for ontologies           About GeneDecksing



LDLRAD3 Antibody Products: 
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Abcam antibodies for LDLRAD3
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LSBio Antibodies in human, mouse, rat for LDLRAD3 

Assay Products for LDLRAD3: 
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Cloud-Clone Corp. ELISAs for LDLRAD3 
Cloud-Clone Corp. CLIAs for LDLRAD3


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
2 InterPro protein domains:
 IPR002172 LDrepeatLR_classA_rpt
 IPR023415 LDLR_class-A_CS

Graphical View of Domain Structure for InterPro Entry Q86YD5

ProtoNet protein and cluster: Q86YD5

1 Blocks protein domain: IPB002172 Low density lipoprotein-receptor

UniProtKB/Swiss-Prot: LRAD3_HUMAN, Q86YD5
Similarity: Belongs to the LDLR family
Similarity: Contains 3 LDL-receptor class A domains


LDLRAD3 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: LRAD3_HUMAN, Q86YD5
Function: May influence APP processing, resulting in a decrease in sAPP-alpha production and increased
amyloidogenic P3 peptide production (By similarity)

     Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001540beta-amyloid binding IEA--
GO:0005515protein binding ----
     
LDLRAD3 for ontologies           About GeneDecksing


Phenotypes:
     1 MGI phenotypic allele for Ldlrad3 (no phenotypes)

LDLRAD3 for phenotypes           About GeneDecksing

Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for LDLRAD3 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for LDLRAD3

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for LDLRAD3 
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miRNA
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hsa-miR-3164 hsa-miR-3685 hsa-miR-607 hsa-miR-106a hsa-miR-218-1* hsa-miR-301a hsa-miR-519a hsa-miR-105
SwitchGear 3'UTR luciferase reporter plasmidLDLRAD3 3' UTR sequence
Inhib. RNA
Products:
    
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Gene Editing
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Clone
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OriGene ORF clones in mouse, rat for LDLRAD3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: LDLRAD3 (NM_174902)
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                     Customized lentivirus expression plasmids for stable overexpression of LDLRAD3 

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LDLRAD3


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section




Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for LDLRAD3

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for LDLRAD3 (ENSP000003186074) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
ELAVL1ENSP000003852694STRING: ENSP00000385269
About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006898receptor-mediated endocytosis IEA--
GO:0070613regulation of protein processing IEA--

LDLRAD3 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for LDLRAD3 (LRAD3)

Search CenterWatch for drugs/clinical trials and news about LDLRAD3 / LRAD3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for LDLRAD3 gene: 
NM_174902.2  

Unigene Cluster for LDLRAD3:

Low density lipoprotein receptor class A domain containing 3
Hs.745134  [show with all ESTs]
Unigene Representative Sequence: BC042754
6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000528989 ENST00000524419 ENST00000315571(uc001mwk.1 uc010rey.1 uc010rez.1 uc010rfa.1)
ENST00000532490 ENST00000534091 ENST00000529759
miRNA
Products:
     
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8/53 QIAGEN miScript miRNA Assays for microRNAs that regulate LDLRAD3 (see all 53):
hsa-miR-3164 hsa-miR-3685 hsa-miR-607 hsa-miR-106a hsa-miR-218-1* hsa-miR-301a hsa-miR-519a hsa-miR-105
SwitchGear 3'UTR luciferase reporter plasmidLDLRAD3 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for LDLRAD3
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LDLRAD3
Clone
Products:
     
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OriGene ORF clones in mouse, rat for LDLRAD3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: LDLRAD3 (NM_174902)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for LDLRAD3
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LDLRAD3
Sirion Biotech Customized lentivirus for stable overexpression of LDLRAD3 
                     Customized lentivirus expression plasmids for stable overexpression of LDLRAD3 
Primer
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OriGene qSTAR qPCR primer pairs in human, mouse for LDLRAD3
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  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LDLRAD3
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LDLRAD3

Additional mRNA sequence: 

AK075546.1 AK293930.1 AK299186.1 BC042754.1 BC136286.1 BC143823.1 BC143824.1 

7 DOTS entries:

DT.102821304  DT.406497  DT.100781962  DT.120719946  DT.120719976  DT.95148028  DT.120719880 

24/69 AceView cDNA sequences (see all 69):

CB045639 AA380138 AA302738 NM_174902 BG830323 BU732126 CD515264 BU101955 
CB144599 BX283894 AI553724 BQ435209 AK075546 BU633144 W68447 BI966006 
AA383623 AW341957 AW291044 BX477884 BU195012 AI815852 CK904049 BX472504 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

LDLRAD3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GGCAAGAGAC
LDLRAD3 Expression
About this image


See LDLRAD3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for LDLRAD3

SOURCE GeneReport for Unigene cluster: Hs.745134

UniProtKB/Swiss-Prot: LRAD3_HUMAN, Q86YD5
Tissue specificity: Expressed at high levels in brain, lung, skeletal muscle, and pancreas. Expressed at moderate
levels in heart, placenta, and kidney but not detected in the liver

    SABiosciences Custom PCR Arrays for LDLRAD3
Primer
Products:
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QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LDLRAD3
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LDLRAD3

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for LDLRAD3 gene from 7/14 species (see all 14)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Ldlrad31 , 5 low density lipoprotein receptor class A domain containing more1, 5 89.57(n)1
95.94(a)1
  2 (54.11 cM)5
2415761  NM_178886.21  NP_849217.21 
 1019502035 
chicken
(Gallus gallus)
Aves LDLRAD31 low density lipoprotein receptor class A domain containing more 76.81(n)
80.72(a)
  423160  XM_421086.3  XP_421086.3 
lizard
(Anolis carolinensis)
Reptilia LDLRAD36
low density lipoprotein receptor class A domain co...
71(a)
1 ↔ 1
1(53859856-54087876)
tropical clawed frog
(Xenopus tropicalis)
Amphibia Str.30492 Silurana tropicalis cDNA clone IMAGE5379334 76.07(n)    BC064324.1 
zebrafish
(Danio rerio)
Actinopterygii ldlrad31 low density lipoprotein receptor class A domain containing more 61.43(n)
54.85(a)
  570705  NM_001130607.1  NP_001124079.1 
fruit fly
(Drosophila melanogaster)
Insecta CG67396
--
7(a)
1 → many
2L(7608390-7616528)
worm
(Caenorhabditis elegans)
Secernentea F09B12.56
lrx-16
(see all 3)
Protein LRX-1
(see all 3)
17(a)
13(a)
(see all 3)
many ↔ many
many ↔ many
(see all 3)
X(15084749-15088135)
V(12252647-12255394)


ENSEMBL Gene Tree for LDLRAD3 (if available)
TreeFam Gene Tree for LDLRAD3 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for LDLRAD3 gene
LRP122  LRP22  LRP32  LRP102  
18/43 SIMAP similar genes for LDLRAD3 using alignment to 3 protein entries:     LRAD3_HUMAN (see all proteins) (see all similar genes):
HC6    SEPSECS    DYNC2LI1    TNNT1    CASC4    KIAA1651
ZNF257    ARL6IP5    C14orf105    RBP7    RHBG    pp12301
IK    VPS33A    C12orf76    DPP9    ZNF799    ADCK1

LDLRAD3 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/6460 SNPs in LDLRAD3 are shown (see all 6460)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1807354581,2
--35963644(+) GAGGCA/GGAGGT 1 -- us2k10--------
rs2005316981,2
C--35963722(+) AATAA-/ATAG  
        
ATAAA
1 -- us2k10--------
rs1862654391,2
--35963765(+) AATAAA/GGTTTT 1 -- us2k10--------
rs761854201,2
C--35963810(+) ATTTAC/TATTTA 1 -- us2k10--------
rs1904721611,2
--35963900(+) TGATGC/TGTCCA 1 -- us2k10--------
rs1155414011,2
F--35963959(+) CTTTCC/TGTATC 1 -- us2k11Minor allele frequency- T:0.02WA 118
rs1820661491,2
--35964096(+) ATGCAC/TAGGAC 1 -- us2k10--------
rs1181679391,2
F--35964152(+) GGGACG/AATCTC 1 -- us2k11Minor allele frequency- A:0.01NA 120
rs1482087101,2
--35964168(+) TATTCA/GTCAAT 1 -- us2k10--------
rs1171062331,2
C,F--35964246(+) AACTAT/CGGAAC 1 -- us2k11Minor allele frequency- C:0.01NA 120

HapMap Linkage Disequilibrium report for LDLRAD3 (35965531 - 36215531 bp, first 250kb of LDLRAD3)

Structural Variations
     Database of Genomic Variants (DGV) 10/16 variations for LDLRAD3 (see all 16):    About this table     
Variant IDTypeSubtypePubMed ID
esv2670859CNV Deletion23128226
esv1443244CNV Deletion17803354
esv2744345CNV Deletion23290073
esv2422305CNV Duplication17116639
esv2548850CNV Insertion19546169
nsv513311CNV Insertion21212237
nsv7735CNV Insertion18451855
esv269629CNV Insertion20981092
esv271874CNV Insertion20981092
esv1294533CNV Insertion17803354

SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing LDLRAD3
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

LDLRAD3 for disorders           About MalaCards

LDLRAD3 for disorders           About GeneDecksing

Genetic Association Database (GAD): LDLRAD3
Human Genome Epidemiology (HuGE) Navigator: LDLRAD3 (2 documents)

Export disorders for LDLRAD3 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for LDLRAD3 gene integrated from 9 sources:
(articles sorted by number of sources associating them with LDLRAD3)
    Utopia: connect your pdf to the dynamic
world of online information

  1. LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking. (PubMed id 21795536)1, 2 Ranganathan S.... Strickland D.K. (2011)
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
  3. Analysis of 9p24 and 11p12-13 regions in autism spect rum disorders: rs1340513 in the JMJD2C gene is associated with ASDs in Finnish sample. (PubMed id 20410850)1, 4 KantojAorvi K....JAorvelAo I. (2010)
  4. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
  6. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
  7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 143458 HGNC: 27046 AceView: LOC143458 Ensembl:ENSG00000179241 euGenes: HUgn143458
ECgene: LDLRAD3 H-InvDB: LDLRAD3

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for LDLRAD3 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for LDLRAD3 gene:
Search GeneIP for patents involving LDLRAD3

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore Custom Antibody & Bulk Services
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 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for LDLRAD3  
 Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for LDLRAD3  
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 OriGene Custom Antibody Services for LDLRAD3   OriGene Custom Protein Services for LDLRAD3  

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat LDLRAD3
 QIAGEN SeqTarget long-range PCR primers for resequencing LDLRAD3
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LDLRAD3
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LDLRAD3
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 GenScript Custom Purified and Recombinant Proteins Services for LDLRAD3 GenScript cDNA clones with any tag delivered in your preferred vector for LDLRAD3
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 GenScript Custom overexpressing Cell Line Services for LDLRAD3 CloneReady with Over 120,000 Genes
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 Regulatory tfbs in LDLRAD3 promoter
 Search Chromatin IP Primers for LDLRAD3
 RT2 qPCR Primer Assay in human, mouse, rat LDLRAD3
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 Browse Sino Biological Proteins and Antibodies
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
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 See all of Abcam's Antibodies, Kits and Proteins for LDLRAD3
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 Proteins for LDLRAD3
 Antibodies for LDLRAD3
 ELISAs for LDLRAD3
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 Search LifeMap BioReagents cell lines for LDLRAD3
 Gene Synthesis
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 Variant Library Synthesis
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 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LDLRAD3
 SwitchGear 3'UTR luciferase reporter plasmids for LDLRAD3
 Browse SwitchGear Promoter luciferase reporter plasmids for LDLRAD3
 Search ThermoFisher Antibodies for LDLRAD3
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LDLRAD3
 inGenious Targeting Laboratory - Custom generated mouse model solutions for LDLRAD3
 inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for LDLRAD3
Customized:
 lentivirus for stable overexpression of LDLRAD3
 lentivirus expression plasmids for stable overexpression of LDLRAD3
 adenovirus for overexpression of LDLRAD3
 LSBio Antibodies in human, mouse, rat for LDLRAD3
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
       
GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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transforming growth factor, beta 1
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The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


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