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LDLRAD3 Gene

protein-coding   GIFtS: 43
GCID: GC11P035923

Low Density Lipoprotein Receptor Class A Domain Containing...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Low Density Lipoprotein Receptor Class A Domain Containing 31 2
LRAD32
Low-Density Lipoprotein Receptor Class A Domain-Containing Protein 32

External Ids:    HGNC: 270461   Entrez Gene: 1434582   Ensembl: ENSG000001792417   UniProtKB: Q86YD53   

Export aliases for LDLRAD3 gene to outside databases

Previous GC identifer: GC11P035664


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for LDLRAD3 Gene:
LDLRAD3 (low density lipoprotein receptor class A domain containing 3) is a protein-coding gene. GO annotations related to this gene include beta-amyloid binding. An important paralog of this gene is LRP12.

UniProtKB/Swiss-Prot: LRAD3_HUMAN, Q86YD5
Function: May influence APP processing, resulting in a decrease in sAPP-alpha production and increased
amyloidogenic P3 peptide production (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the LDLRAD3 gene promoter:
         ATF-2   Pax-6   CUTL1   Evi-1   HNF-1A   GATA-1   IRF-2   HNF-1   FOXO1a   FOXO1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for LDLRAD3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat LDLRAD3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p13   Ensembl cytogenetic band:  11p13   HGNC cytogenetic band: 11p13

LDLRAD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LDLRAD3 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P035923:  view genomic region     (about GC identifiers)

Start:
35,965,531 bp from pter      End:
36,253,686 bp from pter
Size:
288,156 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: LRAD3_HUMAN, Q86YD5 (See protein sequence)
Recommended Name: Low-density lipoprotein receptor class A domain-containing protein 3 precursor  
Size: 345 amino acids; 37419 Da
Subunit: Interacts with APP precursor C-terminus (By similarity)
Secondary accessions: B9EG81 Q8NBJ0

Explore the universe of human proteins at neXtProt for LDLRAD3: NX_Q86YD5

Explore proteomics data for LDLRAD3 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn24

  • See LDLRAD3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_777562.1  
    ENSEMBL proteins: 
     ENSP00000433954   ENSP00000434313   ENSP00000318607  

    LDLRAD3 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for LDLRAD3
    OriGene Custom MassSpec
    OriGene Custom Protein Services for LDLRAD3
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    Novus Biologicals LDLRAD3 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for LDLRAD3

     
    Search eBioscience for Proteins for LDLRAD3 

     
    antibodies-online proteins for LDLRAD3 (4 products) 

     
    antibodies-online peptides for LDLRAD3

    LDLRAD3 Antibody Products:

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    Novus Biologicals LDLRAD3 Antibodies
    Abcam antibodies for LDLRAD3
    Cloud-Clone Corp. Antibodies for LDLRAD3
    Search ThermoFisher Antibodies for LDLRAD3
    antibodies-online antibodies for LDLRAD3 (20 products) 

    LDLRAD3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for LDLRAD3
    Cloud-Clone Corp. CLIAs for LDLRAD3
    Search eBioscience for ELISAs for LDLRAD3 
    antibodies-online kits for LDLRAD3 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR002172 LDrepeatLR_classA_rpt
     IPR023415 LDLR_class-A_CS

    Graphical View of Domain Structure for InterPro Entry Q86YD5

    ProtoNet protein and cluster: Q86YD5

    1 Blocks protein domain: IPB002172 Low density lipoprotein-receptor

    UniProtKB/Swiss-Prot: LRAD3_HUMAN, Q86YD5
    Similarity: Belongs to the LDLR family
    Similarity: Contains 3 LDL-receptor class A domains


    Find genes that share domains with LDLRAD3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: LRAD3_HUMAN, Q86YD5
    Function: May influence APP processing, resulting in a decrease in sAPP-alpha production and increased
    amyloidogenic P3 peptide production (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001540beta-amyloid binding IEA--
    GO:0005515protein binding ----
         
    Find genes that share ontologies with LDLRAD3           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Ldlrad3 (no phenotypes)

    Find genes that share phenotypes with LDLRAD3           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for LDLRAD3

    miRNA
    Products:
        
    miRTarBase miRNAs that target LDLRAD3:
    hsa-mir-744-5p (MIRT037641)

    Block miRNA regulation of human, mouse, rat LDLRAD3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate LDLRAD3 (see all 53):
    hsa-miR-3164 hsa-miR-3685 hsa-miR-607 hsa-miR-106a hsa-miR-218-1* hsa-miR-301a hsa-miR-519a hsa-miR-105
    SwitchGear 3'UTR luciferase reporter plasmidLDLRAD3 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for LDLRAD3
    Predesigned siRNA for gene silencing in human, mouse, rat LDLRAD3

    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for LDLRAD3
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    GenScript: all cDNA clones in your preferred vector: LDLRAD3 (NM_174902)
    Sino Biological Human cDNA Clone for LDLRAD3
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LDLRAD3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LDLRAD3

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LDLRAD3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    LRAD3_HUMAN, Q86YD5: Cell membrane; Single-pass type I membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular3
    cytosol1
    lysosome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--
    GO:0030054cell junction IDA--

    Find genes that share ontologies with LDLRAD3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for LDLRAD3
    Interactions:

        Search GeneGlobe Interaction Network for LDLRAD3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for LDLRAD3 (ENSP000003186074) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006898receptor-mediated endocytosis IEA--
    GO:0070613regulation of protein processing IEA--

    Find genes that share ontologies with LDLRAD3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for LDLRAD3 (LRAD3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for LDLRAD3 gene: 
    NM_174902.2  

    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000528989 ENST00000524419 ENST00000315571(uc001mwk.1 uc010rey.1 uc010rez.1 uc010rfa.1)
    ENST00000532490 ENST00000534091 ENST00000529759
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate LDLRAD3 (see all 53):
    hsa-miR-3164 hsa-miR-3685 hsa-miR-607 hsa-miR-106a hsa-miR-218-1* hsa-miR-301a hsa-miR-519a hsa-miR-105
    SwitchGear 3'UTR luciferase reporter plasmidLDLRAD3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for LDLRAD3
    Predesigned siRNA for gene silencing in human, mouse, rat LDLRAD3
    Clone
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    OriGene ORF clones in mouse, rat for LDLRAD3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: LDLRAD3 (NM_174902)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LDLRAD3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LDLRAD3
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for LDLRAD3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat LDLRAD3
      QuantiTect SYBR Green Assays in human, mouse, rat LDLRAD3
      QuantiFast Probe-based Assays in human, mouse, rat LDLRAD3

    Selected AceView cDNA sequences (see all 69):

    CD515264 AA302738 BQ435209 AK075546 BU732126 BU101955 AI553724 BX283894 
    BU633144 CB144599 AA380138 NM_174902 BG830323 CB045639 AA383623 BM802107 
    BU599420 W68447 AI815852 BI092586 BG033475 BC042754 BX486504 BU178228 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    LDLRAD3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCAAGAGAC
    LDLRAD3 Expression
    About this image

    LDLRAD3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    LDLRAD3 Protein Expression

    UniProtKB/Swiss-Prot: LRAD3_HUMAN, Q86YD5
    Tissue specificity: Expressed at high levels in brain, lung, skeletal muscle, and pancreas. Expressed at moderate
    levels in heart, placenta, and kidney but not detected in the liver

        Custom PCR Arrays for LDLRAD3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LDLRAD3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for LDLRAD3 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ldlrad31 , 5 low density lipoprotein receptor class A domain containing more1, 5 89.57(n)1
    95.94(a)1
      2 (54.11 cM)5
    2415761  NM_178886.21  NP_849217.21 
     1019502035 
    chicken
    (Gallus gallus)
    Aves LDLRAD31 low density lipoprotein receptor class A domain containing more 80.71(n)
    87.86(a)
      423160  XM_004941544.1  XP_004941601.1 
    lizard
    (Anolis carolinensis)
    Reptilia LDLRAD36
    low density lipoprotein receptor class A domain co...
    71(a)
    1 ↔ 1
    1(53859856-54087876)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.30492 Silurana tropicalis cDNA clone IMAGE5379334 76.07(n)    BC064324.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ldlrad31 low density lipoprotein receptor class A domain containing more 65.08(n)
    58.73(a)
      570705  NM_001130607.1  NP_001124079.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta modSP6
    modular serine protease
    11(a)
    many ↔ many
    3R(12478168-12481489)
    worm
    (Caenorhabditis elegans)
    Secernentea M03E7.46
    Protein M03E7.4 (M03E7.4) mRNA, complete cds
    12(a)
    1 → many
    V(5609414-5613219) WBGene00019756


    ENSEMBL Gene Tree for LDLRAD3 (if available)
    TreeFam Gene Tree for LDLRAD3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for LDLRAD3 gene
    LRP122  LRP32  LRP102  
    Selected SIMAP similar genes for LDLRAD3 using alignment to 3 protein entries:     LRAD3_HUMAN (see all proteins) (see all similar genes):
    HC6    SEPSECS    DYNC2LI1    TNNT1    CASC4    KIAA1651
    ZNF257    ARL6IP5    C14orf105    RBP7    RHBG    pp12301
    IK    VPS33A    C12orf76    DPP9    LINC00999    ZNF799

    Find genes that share paralogs with LDLRAD3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for LDLRAD3 (see all 6460)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1807354581,2
    --35963644(+) GAGGCA/GGAGGT 1 -- us2k10--------
    rs2005316981,2
    C--35963722(+) AATAA-/ATAG  
            
    ATAAA
    1 -- us2k10--------
    rs1862654391,2
    --35963765(+) AATAAA/GGTTTT 1 -- us2k10--------
    rs761854201,2
    C--35963810(+) ATTTAC/TATTTA 1 -- us2k10--------
    rs1904721611,2
    --35963900(+) TGATGC/TGTCCA 1 -- us2k10--------
    rs1155414011,2
    F--35963959(+) CTTTCC/TGTATC 1 -- us2k11Minor allele frequency- T:0.02WA 118
    rs1820661491,2
    --35964096(+) ATGCAC/TAGGAC 1 -- us2k10--------
    rs1181679391,2
    F--35964152(+) GGGACG/AATCTC 1 -- us2k11Minor allele frequency- A:0.01NA 120
    rs1482087101,2
    --35964168(+) TATTCA/GTCAAT 1 -- us2k10--------
    rs1171062331,2
    C,F--35964246(+) AACTAT/CGGAAC 1 -- us2k11Minor allele frequency- C:0.01NA 120

    HapMap Linkage Disequilibrium report for LDLRAD3 (35965531 - 36215531 bp, first 250kb of LDLRAD3)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for LDLRAD3 (see all 16):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2670859CNV Deletion23128226
    esv1443244CNV Deletion17803354
    esv2744345CNV Deletion23290073
    esv2422305CNV Duplication17116639
    esv2548850CNV Insertion19546169
    nsv513311CNV Insertion21212237
    nsv7735CNV Insertion18451855
    esv269629CNV Insertion20981092
    esv271874CNV Insertion20981092
    esv1294533CNV Insertion17803354

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing LDLRAD3
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with LDLRAD3           About GenesLikeMe

    Genetic Association Database (GAD): LDLRAD3
    Human Genome Epidemiology (HuGE) Navigator: LDLRAD3 (2 documents)

    Export disorders for LDLRAD3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for LDLRAD3 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with LDLRAD3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking. (PubMed id 21795536)1, 2 Ranganathan S.... Strickland D.K. (J. Neurosci. 2011)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Analysis of 9p24 and 11p12-13 regions in autism spectrum disorders: rs1340513 in the JMJD2C gene is associated with ASDs in Finnish sample. (PubMed id 20410850)1, 4 KantojAorvi K....JAorvelAo I. (Psychiatr. Genet. 2010)
    4. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (DNA Res. 2005)
    5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    6. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (Nature 2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 143458 HGNC: 27046 AceView: LOC143458 Ensembl:ENSG00000179241 euGenes: HUgn143458
    ECgene: LDLRAD3 H-InvDB: LDLRAD3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    PharmGKB entry for LDLRAD3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for LDLRAD3 gene:
    Search GeneIP for patents involving LDLRAD3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
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