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Aliases for LDAH Gene

Aliases for LDAH Gene

  • Lipid Droplet Associated Hydrolase 2 3
  • C2orf43 3 4
  • Chromosome 2 Open Reading Frame 43 2
  • UPF0554 Protein C2orf43 3

External Ids for LDAH Gene

Previous Symbols for LDAH Gene

  • C2orf43

Summaries for LDAH Gene

GeneCards Summary for LDAH Gene

LDAH (Lipid Droplet Associated Hydrolase) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LDAH Gene

Genomics for LDAH Gene

Genomic Location for LDAH Gene

Start:
20,684,014 bp from pter
End:
20,823,130 bp from pter
Size:
139,117 bases
Orientation:
Minus strand

Genomic View for LDAH Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for LDAH Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LDAH Gene

No data available for Regulatory Elements for LDAH Gene

Proteins for LDAH Gene

  • Protein details for LDAH Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H6V9-CB043_HUMAN
    Recommended name:
    UPF0554 protein C2orf43
    Protein Accession:
    Q9H6V9
    Secondary Accessions:
    • B7ZA47
    • B7ZAJ5
    • D6W530
    • E7ESN0
    • Q53T37
    • Q53T58

    Protein attributes for LDAH Gene

    Size:
    325 amino acids
    Molecular mass:
    37319 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for LDAH Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for LDAH Gene

Proteomics data for LDAH Gene at MOPED

Post-translational modifications for LDAH Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for LDAH Gene

Domains for LDAH Gene

Protein Domains for LDAH Gene

InterPro:
Blocks:
ProtoNet:

UniProtKB/Swiss-Prot:

CB043_HUMAN
Family:
  • Belongs to the UPF0554 family.:
    • Q9H6V9
genes like me logo Genes that share domains with LDAH: view

No data available for Gene Families for LDAH Gene

Function for LDAH Gene

miRNA for LDAH Gene

miRTarBase miRNAs that target LDAH

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for LDAH Gene

Localization for LDAH Gene

No data available for Gene Ontology (GO) - Cellular Components for LDAH Gene

Pathways for LDAH Gene

SuperPathways for LDAH Gene

No Data Available

Interacting Proteins for LDAH Gene

Gene Ontology (GO) - Biological Process for LDAH Gene

None

No data available for Pathways by source for LDAH Gene

Transcripts for LDAH Gene

Alternative Splicing Database (ASD) splice patterns (SP) for LDAH Gene

No ASD Table

Relevant External Links for LDAH Gene

GeneLoc Exon Structure for
LDAH
ECgene alternative splicing isoforms for
LDAH

Expression for LDAH Gene

mRNA expression in normal human tissues for LDAH Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for LDAH Gene

genes like me logo Genes that share expressions with LDAH: view

Orthologs for LDAH Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for LDAH Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C2AH2orf43 36
  • 99.38 (n)
  • 99.38 (a)
C2orf43 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C11H2orf43 36
  • 88.78 (n)
  • 82.18 (a)
C2ORF43 37
  • 79 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C17H2orf43 36
  • 85.03 (n)
  • 80.62 (a)
C2orf43 37
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1110057K04Rik 36
  • 76.56 (n)
  • 67.81 (a)
1110057K04Rik 16
1110057K04Rik 37
  • 66 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C2orf43 37
  • 61 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1311648 36
  • 76.44 (n)
  • 66.05 (a)
chicken
(Gallus gallus)
Aves C3H2ORF43 36
  • 61.27 (n)
  • 54.52 (a)
C3H2ORF43 37
  • 52 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C2orf43 37
  • 49 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c2orf43 36
  • 59.96 (n)
  • 52.6 (a)
zebrafish
(Danio rerio)
Actinopterygii C17H2orf43 37
  • 40 (a)
OneToOne
zgc:195062 36
  • 56.39 (n)
  • 48.38 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004435 36
  • 48.51 (n)
  • 33.45 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9186 36
  • 46.83 (n)
  • 35.71 (a)
CG9186 37
  • 33 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea F11C1.4 37
  • 24 (a)
OneToMany
F26A3.1 36
  • 43.54 (n)
  • 32.17 (a)
F26A3.1 37
  • 26 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 39
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G11620 36
  • 43.25 (n)
  • 26.88 (a)
rice
(Oryza sativa)
Liliopsida Os01g0958800 36
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 36 (a)
OneToOne
Species with no ortholog for LDAH:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for LDAH Gene

ENSEMBL:
Gene Tree for LDAH (if available)
TreeFam:
Gene Tree for LDAH (if available)

Paralogs for LDAH Gene

No data available for Paralogs for LDAH Gene

Variants for LDAH Gene

Sequence variations from dbSNP and Humsavar for LDAH Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs2417 -- 20,684,513(+) gggat(C/T)acagg utr-variant-3-prime, nc-transcript-variant
rs2418 -- 20,684,499(+) ccncc(A/C)aaggt utr-variant-3-prime, nc-transcript-variant
rs2419 -- 20,684,502(+) CCCAA(A/G)GTGCT utr-variant-3-prime, nc-transcript-variant
rs9085 -- 20,685,213(-) TTTTA(G/T)CTGTT utr-variant-3-prime, nc-transcript-variant, intron-variant
rs173121 -- 20,822,432(+) gccac(C/G)gcgcc intron-variant

Relevant External Links for LDAH Gene

HapMap Linkage Disequilibrium report
LDAH

No data available for Structural Variations from Database of Genomic Variants (DGV) for LDAH Gene

Disorders for LDAH Gene

No disorders were found for LDAH Gene.

No data available for UniProtKB/Swiss-Prot for LDAH Gene

Publications for LDAH Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Roles and origins of leukocyte lipid bodies: proteomic and ultrastructural studies. (PMID: 17135363) Wan H.C. … Weller P.F. (FASEB J. 2007) 2 3
  3. Novel lipid droplet-associated serine hydrolase regulates macrophage cholesterol mobilization. (PMID: 24357060) Goo Y.H. … Paul A. (Arterioscler. Thromb. Vasc. Biol. 2014) 2 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4

Products for LDAH Gene

Sources for LDAH Gene

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