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Aliases for LDAH Gene

Aliases for LDAH Gene

  • Lipid Droplet Associated Hydrolase 2 3
  • C2orf43 3 4
  • Chromosome 2 Open Reading Frame 43 2
  • UPF0554 Protein C2orf43 3

External Ids for LDAH Gene

Previous HGNC Symbols for LDAH Gene

  • C2orf43

Summaries for LDAH Gene

GeneCards Summary for LDAH Gene

LDAH (Lipid Droplet Associated Hydrolase) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LDAH Gene

Genomics for LDAH Gene

Genomic Location for LDAH Gene

20,684,014 bp from pter
20,823,130 bp from pter
139,117 bases
Minus strand

Genomic View for LDAH Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for LDAH Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LDAH Gene

No data available for Regulatory Elements for LDAH Gene

Proteins for LDAH Gene

  • Protein details for LDAH Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0554 protein C2orf43
    Protein Accession:
    Secondary Accessions:
    • B7ZA47
    • B7ZAJ5
    • D6W530
    • E7ESN0
    • Q53T37
    • Q53T58

    Protein attributes for LDAH Gene

    325 amino acids
    Molecular mass:
    37319 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for LDAH Gene


neXtProt entry for LDAH Gene

Proteomics data for LDAH Gene at MOPED

Post-translational modifications for LDAH Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for LDAH Gene

Domains for LDAH Gene

Protein Domains for LDAH Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the UPF0554 family.
  • Belongs to the UPF0554 family.
genes like me logo Genes that share domains with LDAH: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for LDAH Gene

Function for LDAH Gene

miRNA for LDAH Gene

miRTarBase miRNAs that target LDAH

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for LDAH

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for LDAH Gene

Localization for LDAH Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for LDAH Gene

Pathways for LDAH Gene

SuperPathways for LDAH Gene

No Data Available

Interacting Proteins for LDAH Gene

Gene Ontology (GO) - Biological Process for LDAH Gene


No data available for Pathways by source for LDAH Gene

Transcripts for LDAH Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for LDAH

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for LDAH Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9
SP1: -
SP3: -
SP4: - -

Relevant External Links for LDAH Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for LDAH Gene

mRNA expression in normal human tissues for LDAH Gene

Protein differential expression in normal tissues for LDAH Gene

This gene is overexpressed in Adrenal (10.3) and Bone (8.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for LDAH Gene

genes like me logo Genes that share expressions with LDAH: view

Expression partners for LDAH Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for LDAH Gene

Orthologs for LDAH Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for LDAH Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C11H2orf43 35
  • 88.78 (n)
  • 82.18 (a)
C2ORF43 36
  • 79 (a)
(Canis familiaris)
Mammalia C17H2orf43 35
  • 85.03 (n)
  • 80.62 (a)
C2orf43 36
  • 81 (a)
(Mus musculus)
Mammalia 1110057K04Rik 35
  • 76.56 (n)
  • 67.81 (a)
1110057K04Rik 16
1110057K04Rik 36
  • 66 (a)
(Pan troglodytes)
Mammalia C2AH2orf43 35
  • 99.38 (n)
  • 99.38 (a)
C2orf43 36
  • 99 (a)
(Rattus norvegicus)
Mammalia RGD1311648 35
  • 76.44 (n)
  • 66.05 (a)
(Ornithorhynchus anatinus)
Mammalia C2orf43 36
  • 61 (a)
(Gallus gallus)
Aves C3H2ORF43 35
  • 61.27 (n)
  • 54.52 (a)
C3H2ORF43 36
  • 52 (a)
(Anolis carolinensis)
Reptilia C2orf43 36
  • 49 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c2orf43 35
  • 59.96 (n)
  • 52.6 (a)
(Danio rerio)
Actinopterygii zgc:195062 35
  • 56.39 (n)
  • 48.38 (a)
C17H2orf43 36
  • 40 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004435 35
  • 48.51 (n)
  • 33.45 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9186 35
  • 46.83 (n)
  • 35.71 (a)
CG9186 36
  • 33 (a)
(Caenorhabditis elegans)
Secernentea F26A3.1 35
  • 43.54 (n)
  • 32.17 (a)
F11C1.4 36
  • 24 (a)
F26A3.1 36
  • 26 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 38
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G11620 35
  • 43.25 (n)
  • 26.88 (a)
(Oryza sativa)
Liliopsida Os01g0958800 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 36 (a)
Species with no ortholog for LDAH:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for LDAH Gene

Gene Tree for LDAH (if available)
Gene Tree for LDAH (if available)

Paralogs for LDAH Gene

No data available for Paralogs for LDAH Gene

Variants for LDAH Gene

Sequence variations from dbSNP and Humsavar for LDAH Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs2417 -- 20,684,513(+) gggat(C/T)acagg utr-variant-3-prime, nc-transcript-variant
rs2418 -- 20,684,499(+) ccncc(A/C)aaggt utr-variant-3-prime, nc-transcript-variant
rs2419 -- 20,684,502(+) CCCAA(A/G)GTGCT utr-variant-3-prime, nc-transcript-variant
rs9085 -- 20,685,213(-) TTTTA(G/T)CTGTT utr-variant-3-prime, nc-transcript-variant, intron-variant
rs173121 -- 20,822,432(+) gccac(C/G)gcgcc intron-variant

Relevant External Links for LDAH Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for LDAH Gene

Disorders for LDAH Gene

No disorders were found for LDAH Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for LDAH Gene

Publications for LDAH Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Roles and origins of leukocyte lipid bodies: proteomic and ultrastructural studies. (PMID: 17135363) Wan H.C. … Weller P.F. (FASEB J. 2007) 2 3
  3. Novel lipid droplet-associated serine hydrolase regulates macrophage cholesterol mobilization. (PMID: 24357060) Goo Y.H. … Paul A. (Arterioscler. Thromb. Vasc. Biol. 2014) 2 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4

Products for LDAH Gene

Sources for LDAH Gene

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