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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

LCOR Gene

protein-coding GIFtS: 50
GCID: GC10P098583

ligand dependent nuclear receptor corepressor

Explore 4 diseases affiliated with
LCOR via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Ligand Dependent Nuclear Receptor Corepressor¹ ²		FLJ38026¹
MLR2¹ ² ³ ⁵		Ligand-Dependent Corepressor²
KIAA1795¹ ³ ⁵		LCoR³
Mblk1-Related Protein 2² ³

External Ids:	HGNC: 29503¹	Entrez Gene: 84458²	Ensembl: ENSG00000196233⁷	OMIM: 607698⁵	UniProtKB: Q96JN0³

Export aliases for LCOR gene to outside databases

Previous GC identifer: GC10P092221

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for LCOR:

LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound

nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al.,

2003 (PubMed 12535528)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: LCOR_HUMAN, Q96JN0

Function: May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3' (By

similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of

ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR

Gene Wiki entry for LCOR

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000010.10 NC_018921.1 NT_030059.13

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the LCOR gene promoter:
AML1a RREB-1 HNF-3beta YY1 GATA-2 Meis-1b Nkx6-1 HFH-1 Meis-1a Meis-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: LCOR promoter sequence

Search SABiosciences Chromatin IP Primers for LCOR

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LCOR

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24 Ensembl cytogenetic band: 10q24.1 HGNC cytogenetic band: 10q24

LCOR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LCOR gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10P098583: view genomic region (about GC identifiers)

Start:	98,592,017 bp from pter	End:	98,740,800 bp from pter
Size:	148,784 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: LCOR_HUMAN, Q96JN0 (See protein sequence)

Recommended Name: Ligand-dependent corepressor

Size: 433 amino acids; 47007 Da

Subunit: Interacts with ESR1 and ESR2 in the presence of estradiol. Interacts with CTBP1, HDAC3 and HDAC6. Component of

a large corepressor complex that contains about 20 proteins, including CTBP1, CTBP2, HDAC1 and HDAC2

Subcellular location: Nucleus

Sequence caution: Sequence=BAB47424.1; Type=Erroneous initiation;

1 PDB 3D structure from and Proteopedia for LCOR:

2COB (3D)

Secondary accessions: D3DR47 Q5VW16 Q7Z723 Q86T32 Q86T33 Q8N3L6

Alternative splicing: 2 isoforms: Q96JN0-1 Q96JN0-2

Explore the universe of human proteins at neXtProt for LCOR: NX_Q96JN0

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96JN0

LCOR Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001164236.1 NP_001164237.1 NP_115816.2

ENSEMBL proteins:

ENSP00000360144 ENSP00000360138 ENSP00000348298 ENSP00000443431

Human Recombinant Protein Products:

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	Novus Biologicals LCOR Proteins Novus Biologicals LCOR Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for LCOR

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

LCOR for ontologies About GeneDecksing

LCOR Antibody Products:

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Assay Products for LCOR:

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	Uscn ELISAs and CLIAs for LCOR

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

LCOR for domains About GeneDecksing

2 InterPro domains/families:

IPR009057 Homeodomain-like

IPR007889 HTH_Psq

Graphical View of Domain Structure for InterPro Entry Q96JN0

ProtoNet protein and cluster: Q96JN0

UniProtKB/Swiss-Prot: LCOR_HUMAN, Q96JN0

Similarity: Contains 1 HTH psq-type DNA-binding domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: LCOR_HUMAN, Q96JN0

Function: May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3' (By

similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of

ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR

miRNA Products:		OriGene 3'-UTR Clone: LCOR Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LCOR
		8/252 QIAGEN miScript miRNA Assays for microRNAs that regulate LCOR (see all 252):
		hsa-miR-140-5p hsa-miR-3938 hsa-miR-520f hsa-miR-146a hsa-miR-106a hsa-miR-199a-3p hsa-miR-128 hsa-miR-519a

		SwitchGear 3'UTR luciferase reporter plasmid: LCOR 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for LCOR (see all 4) OriGene shRNA RFP: LCOR OriGene siRNA: LCOR
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Gene Editing
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DNA2.0 Custom Protein Engineering Service for LCOR

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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for LCOR
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LCOR

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0003700	sequence-specific DNA binding transcription factor activity	IEA	--
GO:0008134	transcription factor binding	IEA	--

LCOR for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for LCOR:

Increased gamma-H2AX phosphory

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for LCOR

STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

5/10 Interacting proteins for LCOR (Q96JN0³ ENSP00000348298⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 10)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CTBP2	P56545³, ENSP00000311825⁴	I2D: score=1 STRING: ENSP00000311825
HDAC3	O15379³, ENSP00000302967⁴	I2D: score=1 STRING: ENSP00000302967
HDAC4	P56524³, ENSP00000264606⁴	I2D: score=1 STRING: ENSP00000264606
HDAC6	Q9UBN7³, ENSP00000334061⁴	I2D: score=1 STRING: ENSP00000334061
CTBP1	Q13363³, ENSP00000290921⁴	I2D: score=1 STRING: ENSP00000290921

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	IEA	--
GO:0006357	regulation of transcription from RNA polymerase II promoter	--	--
GO:0006366	transcription from RNA polymerase II promoter	IEA	--

LCOR for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for LCOR
Search CenterWatch for drugs/clinical trials and news about LCOR

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for LCOR gene (3 alternative transcripts):

NM_001170765.1 NM_001170766.1 NM_032440.3

Unigene Cluster for LCOR:

Ligand dependent nuclear receptor corepressor

Hs.644719 [show with all ESTs]

Unigene Representative Sequence: NM_032440

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000371103 ENST00000371097(uc001kms.2 uc001kmu.2) ENST00000356016

ENST00000493486 ENST00000469510 ENST00000498444 ENST00000463415 ENST00000540664(uc001kmr.3 uc009xvg.2)

miRNA Products:		OriGene 3'-UTR Clone: LCOR Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LCOR
		8/252 QIAGEN miScript miRNA Assays for microRNAs that regulate LCOR (see all 252):
		hsa-miR-140-5p hsa-miR-3938 hsa-miR-520f hsa-miR-146a hsa-miR-106a hsa-miR-199a-3p hsa-miR-128 hsa-miR-519a

		SwitchGear 3'UTR luciferase reporter plasmid: LCOR 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Additional cDNA sequence:

AB058698.1 AB072899.1 AB593180.1 AK023248.1 AK095345.1 AL832044.1 AL832106.1 AL834245.2

BC053359.1 BC128542.1

11 DOTS entries:

DT.213421 DT.97796933 DT.205193 DT.101972989 DT.102853 DT.91749310 DT.91817795 DT.91993274

DT.75125365 DT.95230111 DT.95361378

24/51 AceView cDNA sequences (see all 51):

BM829125 AW663968 BC053359 CA391495 AK023248 AI799125 AI826032 CF528377

AI023992 BF095722 AW468300 AA806691 BF432503 CA391494 CK905040 AA429975

AK095345 AB058698 AA342019 CB989676 AL832106 AI806239 AU132324 AI628679

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for LCOR (see all 7) About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	·	2c	·	2d	^	3	^	4	^	5	^	6	^	7	^	8	^	9a	·	9b	·	9c	^	10a	·	10b	^	11a	·	11b	^	12
SP1:					-		-		-		-				-		-																				-
SP2:															-		-
SP3:											-				-		-
SP4:					-		-		-		-				-		-
SP5:					-		-		-		-				-		-		-		-

ECgene alternative splicing isoforms for LCOR

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

LCOR expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACATTTTGGA

About this image

LCOR expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

3 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Brain

Neural Tube

Neural Tube

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See LCOR Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for LCOR

SOURCE GeneReport for Unigene cluster: Hs.644719

UniProtKB/Swiss-Prot: LCOR_HUMAN, Q96JN0

Tissue specificity: Ubiquitous

SABiosciences Custom PCR Arrays for LCOR

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LCOR

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for LCOR gene from 6/13 species (see all 13) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Lcor^{1 , 5}	ligand dependent nuclear receptor corepressor^{1, 5}	96.84(n)¹ 97.92(a)¹		19 (34.94 cM)⁵ 212391¹ NM_172154.4¹ NP_742166.1¹ 41549639⁵
chicken (Gallus gallus)	Aves	LCOR¹	ligand dependent nuclear receptor corepressor	91.84(n) 93.76(a)		423847 XM_421716.3 XP_421716.3
lizard (Anolis carolinensis)	Reptilia	LCOR⁶	--	90(a)	1 ↔ 1	GL343239.1(1982928-1986735)
zebrafish (Danio rerio)	Actinopterygii	lcor¹	ligand dependent nuclear receptor corepressor	64.18(n) 63.13(a)		558560 NM_001079972.1 NP_001073441.1
fruit fly (Drosophila melanogaster)	Insecta	Eip93F⁶	Ecdysone-induced protein 93F	7(a)	1 → many	3R(17774836-17837910)
worm (Caenorhabditis elegans)	Secernentea	mbr-1⁶	honeybee MBlk-1 Related factor family member (mbr-...	16(a)	1 → many	X(10719486-10721990)

ENSEMBL Gene Tree for LCOR (if available)
TreeFam Gene Tree for LCOR (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for LCOR gene

LCORL²

1 SIMAP similar gene for LCOR using alignment to 2 protein entries: LCOR_HUMAN (see all proteins):

LCORL

LCOR for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs139089403^1,2		--	98590096(+)	`AACTC-/AGAGT AGAGT`	3	--	us2k¹		0	--	--	--	--
rs2851^1,2	H	--	98590439(+)	`CTCCAA/CACACC`	3	--	us2k¹		5		MN NS EA	598
rs77613888^1,2	C,	--	98590486(+)	`CACCTA/GGCGGC`	3	--	us2k¹		1		EA	120
rs189405955^1,2		--	98590590(+)	`TCTTCC/TTTCAA`	2	--	us2k¹		0	--	--	--	--
rs192153605^1,2		--	98590598(+)	`CAACAC/TTCAGG`	2	--	us2k¹		0	--	--	--	--
rs184234582^1,2		--	98590655(+)	`TGACAA/TTACTC`	2	--	us2k¹		0	--	--	--	--
rs148233619^1,2		--	98590728(+)	`GCGGGA/GTGGGC`	3	--	us2k¹		0	--	--	--	--
rs189427851^1,2		--	98590800(+)	`CCCGAC/GGCCCA`	3	--	us2k¹		0	--	--	--	--
rs141357221^1,2		--	98590933(+)	`AAGTAC/TTTAAC`	3	--	us2k¹		0	--	--	--	--
rs181824658^1,2		--	98590934(+)	`AGTATC/TTAACG`	3	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for LCOR (98592017 - 98740800 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for LCOR: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LCOR

DNA2.0 Custom Variant and Variant Library Synthesis for LCOR

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

LCOR for disorders           About GeneDecksing

OMIM gene information: 607698    OMIM disorders: --

4 diseases for LCOR:    About MalaCards

portal hypertension hypertension prostate cancer prostatitis

Human Genome Epidemiology (HuGE) Navigator: LCOR (2 documents)

Export disorders for LCOR gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for LCOR gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with LCOR)

Utopia: connect your pdf to the dynamic
world of online information

Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms. (PubMed id 12535528)^{1, 2, 3} Fernandes I.... White J.H. (2003)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Corepressor recruitment by agonist-bound nuclear receptors. (PubMed id 15193453)^{1, 3} White J.H....Yang X.J. (2004)
The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)^{1, 2} Deloukas P.... Rogers J. (2004)
Coordinated histone modifications mediated by a CtBP co-repressor complex. (PubMed id 12700765)^{1, 2} Shi Y.... Shi Y. (2003)
Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)^{1, 2} Nagase T.... Ohara O. (2001)
Ligand-dependent corepressor (LCoR) recruitment by Kru ppel-like factor 6 (KLF6) regulates expression of the cyclin-dependent kinase in hibitor CDKN1A gene. (PubMed id 22277651)¹ Calderon M.R....White J.H. (2012)
miR-615-3p promotes the phagocytic capacity of spleni c macrophages by targeting ligand-dependent nuclear receptor corepressor in cir rhosis-related portal hypertension. (PubMed id 21565892)¹ Jiang A....Yang J. (2011)
Ligand-dependent corepressor acts as a novel androgen receptor corepressor, inhibits prostate cancer growth, and is functionally ina ctivated by the Src protein kinase. (PubMed id 21856747)¹ Asim M....Baniahmad A. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 84458	HGNC: 29503	AceView: MLR2	Ensembl:ENSG00000196233	euGenes: HUgn84458
ECgene: LCOR	H-InvDB: LCOR

(According to HUGE)
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HUGE: KIAA1795

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for LCOR	Pharmacogenomics, SNPs, Pathways

Intellectual Property for LCOR gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for LCOR gene:
Search GeneIP for patents involving LCOR

GeneCards and IP:
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ligand dependent nuclear receptor corepressor

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