V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

LBP Gene

protein-coding GIFtS: 63

GC20P036408

lipopolysaccharide binding protein
(Previous name: lipopolysaccharide-binding protein )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
MGC22233 ^²
OTTHUMP00000030965 ^²

Descriptions
LPS-binding protein ^²
lipopolysaccharide binding protein ^²
lipopolysaccharide-binding protein ^¹, ²

External Ids
HGNC: 6517¹
Entrez Gene: 3929²
UniProtKB: P18428³
Ensembl: ENSG00000129988⁷

Search outside databases for aliases for LBP gene

Previous GC identifers: GC20P036703 GC20P037613 GC20P037660

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for LBP:

The protein encoded by this gene is involved in the acute-phase immunologic response to

gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid,

lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal

permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14

receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice

suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not

for the clearance of LPS from circulation. This protein is part of a family of structurally and

functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP),

and phospholipid transfer protein (PLTP). Finally, this gene is found on chromosome 20,

immediately downstream of the BPI gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: LBP_HUMAN, P18428

Function: Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present

in the outer membrane of all Gram-negative bacteria. The LBP/LPS complex seems to interact with

the CD14 receptor

Gene Wiki entry for LBP (Lipopolysaccharide-binding_protein)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the LBP gene

Entrez Gene cytogenetic band: 20q11.23-q12 Ensembl cytogenetic band: 20q11.23 HGNC cytogenetic band: 20q11.23

LBP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20P036408: (about GC identifiers)

Start:	36,408,299 bp from pter
End:	36,439,067 bp from pter
Size:	30,769 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000020.9 NT_011362.9

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: LBP_HUMAN, P18428 (See protein sequence)

Recommended Name: Lipopolysaccharide-binding protein precursor

Size: 481 amino acids; 53384 Da

Subcellular location: Secreted

Secondary accessions: O43438 Q92672 Q9H403 Q9UD66

REFSEQ proteins: NP_004130.2

ENSEMBL proteins:

ENSP00000217407

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	R&D Systems Recombinant & Natural Proteins for LBP
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (LBP)
	Human Recombinant Proteins from Abnova (LBP)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005615	extracellular space	ISS	2477488
GO:0005634	nucleus	IDA	18029348

About this table

Antibodies for LBP:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for LBP
	R&D Systems Antibodies for LBP
	Antibodies from Abcam (LBP), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (LBP)
	Novus Biologicals Antibody for LBP

Assays for LBP:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P18428

ProtoNet protein and cluster: P18428

1 Blocks protein family: IPB001124 Lipid-binding serum glycoprotein

UniProtKB/Swiss-Prot: LBP_HUMAN, P18428

Similarity: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (LBP)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004139

Applied Biosystems Silencer® siRNAs for LBP

Sigma-Aldrich siRNA and siRNA Panels for LBP

Sigma-Aldrich shRNA for LBP

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for LBP
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_004139
Myc/DDK tagged cDNA clone in CMV expression vector: NM_004139
untagged cDNA clone in CMV expression vector: NM_004139

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_004139

UniProtKB/Swiss-Prot: LBP_HUMAN, P18428

Function: Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present

in the outer membrane of all Gram-negative bacteria. The LBP/LPS complex seems to interact with

the CD14 receptor

Genatlas biochemistry entry for LBP:

lipopolysaccharide,acute-phase protein specifically binding to the lipid A moiety of liposaceharide

(LPS,endotoxin) from the cell wall of Gram- bacteria binding protein,and directing it to the CD14

receptor mainly expressed by phagocytes

1 MGI mutant phenotype (inferred from 2 alleles) (MGI details for Lbp):

immune system

5/6 Gene Ontology (GO) molecular function terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001530	lipopolysaccharide binding	IEA	--
GO:0005102	receptor binding	ISS	2477488
GO:0008289	lipid binding	IEA	--
GO:0043498	cell surface binding	ISS	2477488
GO:0051636	Gram-negative bacterial cell surface binding	ISS	2402637

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/10 Sigma-Aldrich "Your Favorite Gene" Pathways for LBP (Your Favorite Gene powered by Ingenuity) (see all 10 )

LXR/RXR Activation
Acute Phase Response Signaling
Actin Cytoskeleton Signaling
LPS-stimulated MAPK Signaling
Hepatic Cholestasis

GeneDecks LBP for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for LBP

5/13 Interacting proteins for LBP (ENSP00000217407³) via UniProtKB, MINT, and/or STRING (see all 13 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CD14	ENSP00000304236³	STRING (score=.995)
IL6	ENSP00000258743³	STRING (score=.961)
STAT3	ENSP00000264657³	STRING (score=.932)
FOS	ENSP00000306245³	STRING (score=.899)
TLR4	ENSP00000363089³	STRING (score=.831)

About this table

5/19 Gene Ontology (GO) biological process terms (links to tree view) (see all 19 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0002281	macrophage activation during immune response	ISS	2402637
GO:0006869	lipid transport	IEA	--
GO:0006953	acute-phase response	ISS	2477488
GO:0006968	cellular defense response	ISS	2402637
GO:0008228	opsonization	ISS	2477488

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for LBP
10/25 Novoseek chemical compound relationships for LBP gene (see all 25 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
endotoxin	85.52	147	14733729 (5), 17206721 (5), 10515819 (4), 8704115 (4) (see all 69)
lipoteichoic acid	69.49	32	12594207 (4), 16928689 (4), 9925653 (2), 11828371 (2) (see all 8)
phospholipid	50.63	42	8985160 (2), 9103463 (2), 10768924 (2), 15784577 (2) (see all 26)
monophosphoryl lipid a	43.46	3	17254389 (1), 7515085 (1)
peptidoglycan	37.77	4	15294986 (1), 8051139 (1), 11705912 (1)
lipid	30.45	34	7536794 (3), 16303759 (3), 9441745 (2), 10607703 (2) (see all 19)
fibrinogen	25.45	11	10607703 (3), 9715256 (1), 18277064 (1), 17081803 (1) (see all 7)
il 10	23.86	1	16050543 (1)
glycolipid	23.48	2	9568897 (1)
polysulfone	18.17	1	7507806 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (LBP)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004139

Sigma-Aldrich siRNA and siRNA Panels for LBP

Sigma-Aldrich shRNA for LBP

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_004139

REFSEQ mRNAs for LBP gene:

NM_004139.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_004139

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_004139
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_004139
                                 untagged cDNA clone in CMV expression vector: NM_004139

Additional cDNA sequence:

AF105067.1 AK313625.1 AY344471.1 BC022256.1 CR592006.1 CR606921.1 CR613938.1 CR621941.1

M35533.1

2 DOTS entries:

DT.110781 DT.100776620

24/59 AceView cDNA sequences (see all 59 ):

NM_004139 CA489550 CR621941 BX406391 AV658726 CB164493 BG618841 CR592006

BX325221 CB163947 CR606921 CR613938 R29149 T61393 BG618594 BX405350

BQ669569 AL531909 BX423833 AL708488 AL557972 BI763303 CB161731 CB162798

highest scoring ESTs for LBP:

AF105067 AL531908 AL557972 AW193105 AW953660 BG567007 BI762328 BQ028088 BX108847 BX325220

Unigene Cluster for LBP:

Lipopolysaccharide binding protein

Hs.154078 [show with all ESTs]

Unigene Representative Sequence: NM_004139

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000217407

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

LBP expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for LBP

¹ / ² / ³

5 probe-sets matching LBP gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
35013_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	AF013512	0.20	1.00	0.72	1
214461_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_004139	0.60	1.00	0.82	1
211652_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	M35533	0.60	1.00	0.82	1
214461_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
211652_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks LBP for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AACCTGGAAC

SOURCE GeneReport for Unigene cluster: Hs.154078
Expression variation in blood from EXPOLDB for LBP

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for LBP gene from 5/7 species (see all 7 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	LBP¹	--	lipopolysaccharide binding protein	83.91(n) 79.8(a)	485869 XM_542993.2 XP_542993.2
chimpanzee (Pan troglodytes)	LBP¹	--	lipopolysaccharide binding protein	98.71(n) 97.54(a)	458239 XM_514638.2 XP_514638.2
cow (Bos taurus)	LBP¹	--	lipopolysaccharide binding protein	80.59(n) 75.11(a)	512242 NM_001038674.1 NP_001033763.1
rat (Rattus norvegicus)	Lbp¹	--	lipopolysaccharide binding protein	75.82(n) 68.51(a)	29469 NM_017208.1 NP_058904.1
mouse (Mus musculus)	Lbp^{1, 5}	2 (83.00 cM)⁵	lipopolysaccharide binding protein^{1, 5}	76.02(n)¹ 68.14(a)¹	16803¹ NM_008489.2¹ NP_032515.2¹ AA207419⁵ AI643881⁵ (see all 17)

About this table Species with no ortholog for LBP

ENSEMBL Gene Tree for LBP

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for LBP gene

BPIL2² PLTP² BPI²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/385 NCBI SNPs in LBP are shown (see all 385 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 145)

AB	SNP ID	Valid	Chr 20 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs2232618^1,2	A,C,F,H	36435175(+)	`ACACCT/CTCTAC`	1	L/F	mis¹ ese³		15	NA EU EA WA	1102
--	rs5741812^1,2	A,C,F,H	36407413(+)	`TCATGA/TCTCCT`	1	--	ng5¹		14	NA EU EA WA	1010
	rs2232578^1,2	A,C,F,H	36408129(+)	`GATCTA/GGGCAG`	1	--	ng5¹		11	EA NA EU WA	2092
	rs2232607^1,2	C,F,H,O	36426747(+)	`CTCGGA/GTTATG`	1	D/G	mis¹ ese³		14	EU EA WA NA	1024
	rs2232571^1,2	A,C,F,H	36407498(+)	`GCCATT/CGGAAA`	1	--	ng5¹		18	NA EU EA WA	1228
	rs1780617^1,2	A,C,F,H	36407571(+)	`AAGggA/Gcatgt`	1	--	ng5¹		21	NA EA EU MN WA	1704
	rs1780616^1,2	A,C,F,H	36406356(+)	`CAATTC/TCTGCT`	1	--	ng5¹		10	NA EU EA WA	606
	rs2232573^1,2	A,C,F,H	36407708(+)	`atgtaT/Cttaag`	1	--	ng5¹		10	NA EU EA WA	596
	rs2232615^1,2	C,F,H	36431162(+)	`GGAGAT/CAGATG`	1	T/I	mis¹		4	EU EA WA	406
	rs2232580^1,2	C,F,H	36408359(+)	`CCTGCC/TGTCCA`	1	P/L	mis¹ ese³		12	EU EA WA NA	1002

About this table

HapMap Linkage Disequilibrium images for LBP (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 151990

10/47 Novoseek disease relationships for LBP gene (see all 47 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
response acute phase	74.09	37	8668165 (2), 8588345 (2), 8021509 (2), 9442384 (2) (see all 18)
shock septic	73.94	18	14624690 (3), 7963737 (2), 11739189 (2), 1284855 (1) (see all 11)
gram-negative bacterial infections	72.03	4	8432532 (1), 9380744 (1), 7678583 (1), 7504510 (1)
sepsis	67.13	101	11373419 (5), 18552695 (5), 16512634 (5), 16569262 (4) (see all 35)
systemic inflammatory response syndrome	65.76	12	18552695 (2), 16569262 (1), 16875458 (1), 7538550 (1) (see all 8)
necrosis	59.10	42	7685250 (2), 1281827 (1), 7543094 (1), 7562749 (1) (see all 37)
inflammation	43.66	25	7562749 (2), 17601541 (2), 8418776 (2), 11605136 (1) (see all 17)
nasal epithelium	43.61	2	12427544 (1)
bacterial infections	42.80	14	9360683 (2), 16407966 (2), 17259880 (2), 17328727 (1) (see all 9)
hepatitis alcoholic	42.34	2	10803780 (1)

About this table

Genetic Association Database: LBP
Human Genome Epidemiology Navigator: LBP (18 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/393 PubMed articles for LBP gene (see all 393 ):

The genomic organization of the genes for human lipopolysaccharide binding protein (LBP) and bactericidal permeability increasing protein (BPI) is highly conserved. (PubMed id 9240454)^{1, 3, 4} Hubacek J.A.... Schmitz G. (1997)
Similar organization of the lipopolysaccharide-binding protein (LBP) and phospholipid transfer protein (PLTP) genes suggests a common gene family of lipid-binding proteins. (PubMed id 9441745)^{1, 3, 4} Kirschning C.J.... Schumann R.R. (1997)
Bactericidal/permeability-increasing protein and lipopolysaccharide (LPS)-binding protein. LPS binding properties and effects on LPS- mediated cell activation. (PubMed id 7517398)^{1, 3, 4} Wilde C.G.... Scott R.W. (1994)
Polymorphisms in the lipopolysaccharide-binding protein and bactericidal/permeability-increasing protein in patients with myocardial infarction. (PubMed id 12521224)^{1, 3, 6} Hubacek J.A....Poledne R. (2002)
Gene variants of the bactericidal/permeability increasing protein and lipopolysaccharide binding protein in sepsis patients: gender-specific genetic predisposition to sepsis. (PubMed id 11373419)^{1, 3, 6} Hubacek J.A....Schmitz G. (2001)
Characterization of a single nucleotide polymorphism in the lipopolysaccharide binding protein and its association with sepsis. (PubMed id 12615620)^{1, 3, 6} Barber R.C. and O'Keefe G.E. (2003)
The BPI/LBP family of proteins: a structural analysis of conserved regions. (PubMed id 9568897)^{1, 3, 4} Beamer L.J.... Eisenberg D. (1998)
The genes for the lipopolysaccharide binding protein (LBP) and the bactericidal permeability increasing protein (BPI) are encoded in the same region of human chromosome 20. (PubMed id 8432532)^{1, 2, 3} Gray P.W....Shows T.B. (1993)
Structure and function of lipopolysaccharide binding protein. (PubMed id 2402637)^{1, 3, 4} Schumann R.R.... Ulevitch R.J. (1990)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{3, 4} Deloukas P....Rogers J. (2001)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 3929	HGNC: 6517	AceView: LBP	Ensembl:ENSG00000129988	euGenes: HUgn3929
ECgene: LBP	H-InvDB: LBP

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for LBP
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for LBP:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for LBP-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for LBP		Antibodies for LBP
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for LBP		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (LBP)
	Antibodies (LBP)
	Search for Chimera RNAi
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (LBP)
	Antibodies (LBP)

Search OriGene for LBP

Search Tocris compounds for LBP

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for LBP

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
LBP Gene at Home site.
Version 2.41.1
server4.xennexinc.com

LBP Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for LBP

Summaries
for LBP

Genomic Location
for LBP

Proteins
for LBP

Protein Domains/
Families
for LBP

Gene Function
for LBP

Pathways & Interactions
for LBP

Drugs & Compounds
for LBP

Transcripts
for LBP

Expression
for LBP

Orthologs
for LBP

Paralogs
for LBP

SNPs/Variants
for LBP

Disorders & Mutations
for LBP

Medical News
for LBP

Publications
for LBP

Search for LBP

Genome Databases showing LBP

Other Databases showing LBP

Specialized Databases showing LBP

Licensable Technologies
for LBP

Services
for LBP

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

LBP Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor LBP

Summariesfor LBP

Genomic Locationfor LBP

Proteinsfor LBP

Protein Domains/Familiesfor LBP

Gene Functionfor LBP

Pathways & Interactionsfor LBP

Drugs & Compoundsfor LBP

Transcriptsfor LBP

Expression for LBP

Orthologsfor LBP

Paralogsfor LBP

SNPs/Variantsfor LBP

Disorders & Mutationsfor LBP

Medical Newsfor LBP

Publicationsfor LBP

Search for LBP

Genome Databases showing LBP

Other Databases showing LBP

Specialized Databases showing LBP

Licensable Technologiesfor LBP

Servicesfor LBP

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for LBP

Summaries
for LBP

Genomic Location
for LBP

Proteins
for LBP

Protein Domains/
Families
for LBP

Gene Function
for LBP

Pathways & Interactions
for LBP

Drugs & Compounds
for LBP

Transcripts
for LBP

Expression
for LBP

Orthologs
for LBP

Paralogs
for LBP

SNPs/Variants
for LBP

Disorders & Mutations
for LBP

Medical News
for LBP

Publications
for LBP

Licensable Technologies
for LBP

Services
for LBP