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Aliases & Descriptions for LARP4
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Aliases DKFZp686E039 2 MGC74631 2 PP13296 1 , 2
Descriptions La ribonucleoprotein domain family member 4 3 La ribonucleoprotein domain family, member 4 2 c-Mpl binding protein 2
Search outside databases for aliases for LARP4 gene
Summaries for LARP4 (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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Gene Wiki entry for LARP4
Genomic Location for LARP4
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
SABiosciences )About This Section
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Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the LARP4 gene Entrez Gene cytogenetic band: 12q13.13 Ensembl cytogenetic band: 12q13.13 HGNC cytogenetic band: 12q13.12 LARP4 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure
GeneLoc location for GC12P049082:
(about GC identifiers )
Start:
49,080,917 bp from pter
End:
49,160,055 bp from pter
Size:
79,139 bases
Orientation:
plus strand
RefSeq DNA sequence: NC_000012.10 NT_029419.11 Proteins for LARP4
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: LARP4_HUMAN, Q71RC2 (See
protein sequence )Recommended Name: La-related protein 4 Size : 724 amino acids; 80596 Da
Sequence caution : Sequence=BAC86052.1; Type=Erroneous initiation; Note=Translation N-terminallyextended;
PDB structures from and Proteopedia : 2CQK (3D)
 
Secondary accessions : A8K6T1 Q5CZ97 Q6ZV14 Q96NF9Alternative splicing : 4 isoforms : Q71RC2-1 Q71RC2-2 Q71RC2-3 Q71RC2-4
Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins (3 alternative transcripts):
NP_443111.3 NP_954658.1 NP_954660.1 ENSEMBL proteins: ENSP00000293618 ENSP00000381482 ENSP00000340901 ENSP00000344664 ENSP00000381490 Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells Antibodies for LARP4: Assays for LARP4:
Protein
Domains/ Families for LARP4(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry Q71RC2 ProtoNet protein and cluster: Q71RC2
UniProtKB/Swiss-Prot: LARP4_HUMAN, Q71RC2 Similarity : Contains 1 HTH La-type RNA-binding domainSimilarity : Contains 1 RRM (RNA recognition motif) domain
Gene Function for LARP4
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
from Invitrogen ,
Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3 ): NM_199190 Applied Biosystems Silencer ® siRNAs for LARP4 Sigma-Aldrich siRNA for LARP4 Sigma-Aldrich shRNA for LARP4 Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 3 ): NM_052879                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 3 ): NM_052879                                  untagged cDNA clones in CMV expression vector (see all 4 ): AL832198  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_199188 1 Gene Ontology (GO) molecular function term (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0003723 RNA binding
IEA --
About this table
Pathways & Interactions for LARP4
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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Drugs & Compounds for LARP4 (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Browse Tocris compounds for LARP4
Transcripts for LARP4(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
Abnova ,
siRNAs from Applied Biosystems ,
Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
Tagged/untagged cDNA clones from
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3 ): NM_199190 Sigma-Aldrich siRNA for LARP4 Sigma-Aldrich shRNA for LARP4 Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_052879 NM_199188 NM_199190
REFSEQ mRNAs for LARP4 gene (3 alternative transcripts): NM_052879.3 NM_199188.1 NM_199190.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_052879 NM_199188 NM_199190
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3 ): NM_052879                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 3 ): NM_052879                                  untagged cDNA clones in CMV expression vector (see all 4 ): AL832198  
Additional cDNA sequence: AF131755.1 AF370416.1 AK055521.1 AK125113.1 AK291746.1 AL050205.1 AL832198.1 AL833272.1 AY004310.1 BC017395.1 BC022377.1 BC032444.2 BC063479.1 BX647457.1 CR936626.1
12 DOTS entries : DT.446301 DT.97794300 DT.91762940 DT.101984628 DT.91979480 DT.91957330 DT.310491 DT.100739023 DT.100789960 DT.92414397 DT.92066168 DT.309208
24/277 AceView cDNA sequences (see all 277
):AI635518 BM468853 BC022377 NM_199190 AI379558 BQ186310 AW614937 BM465910 R83608 BC032444 AI168148 NM_199188 BM454808 AA236079 AI360645 AI275480 BQ435023 AA954726 AW611857 BQ431746 BM977672 N29797 Z40209 AI239476
highest scoring ESTs for LARP4 :AL043283 AL050205 AA194139 AA194141 AA210698 AA235371 AA236010 AA282284 AA329334 AA333290
Unigene Cluster for LARP4: La ribonucleoprotein domain family, member 4 Hs.26613 [show with all ESTs ] Unigene Representative Sequence: NM_199188 GeneLoc Exon Structure 5/7 Alternative Splicing Database (ASD) splice patterns (SP) for LARP4 (see all 7
) ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b SP1 :                             -       -                 SP2 :         -       -               -   -     -                 SP3 :         -       -               -   -       -               SP4 :               -               -                       SP5 :         -       -               -                      
About this scheme ECgene alternative splicing isoforms for LARP4 5 Ensembl transcripts including schematic representations : ENST00000293618
ENST00000398464
ENST00000347328
ENST00000341915
ENST00000398473
Expression for LARP4
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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LARP4 expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for LARP4 1 / 2 / 3
13 probe-sets matching LARP4 gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: CATAAAATGTSOURCE GeneReport for Unigene cluster: Hs.26613
Orthologs for LARP4
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for LARP4 gene from 5/7 species (see all 7
)
About this table Species with no ortholog for LARP4 ENSEMBL Gene Tree for LARP4 Paralogs for LARP4 (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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Paralogs for LARP4 gene LARP5 2
SNPs/Variants for LARP4 (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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HapMap Linkage Disequilibrium images for LARP4 (up to first 250kb)
Disorders & Mutations for LARP4
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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Medical News for LARP4 (Possibly Related Articles in
Doctor's Guide )
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Publications for LARP4 (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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9 PubMed articles for LARP4 gene :
Search for LARP4
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing LARP4
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing LARP4
(According to HUGE )
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Specialized Databases showing LARP4 (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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-- Services for LARP4 (Reagents available from Applied Biosystems , Antibodies and assays by Cell
Signaling Technology , Abcam , Novus Biologicals ,Sigma-Aldrich , R&D Systems , Millipore , Abnova , and/or Invitrogen , Clones available from OriGene ,and/or Invitrogen , Drugs and/or compounds by Sigma-Aldrich , Enzo Life Sciences , and/or Tocris Bioscience )About This Section
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