Services
Jump to Section...
Aliases for LARP2
Databases for LARP2
Disorders for LARP2
Domains/Families for LARP2
Drugs/Compounds for LARP2
Expression for LARP2
Function for LARP2
Location for LARP2
Medical News for LARP2
Orthologs for LARP2
Paralogs for LARP2
Pathways/Interactions for LARP2
Proteins for LARP2
Publications for LARP2
SNPs for LARP2
Search Box for LARP2
Services for LARP2
Summaries for LARP2
Technologies for LARP2
Transcripts for LARP2
TOP
BOTTOM
Aliases & Descriptions for LARP2
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Aliases DKFZp434K245 1 DKFZp686E0316 1 DKFZp686L13217 2 FLJ10378 1 MGC117277 2 MGC75174 2
Descriptions La ribonucleoprotein domain family member 2 2 , 3 La ribonucleoprotein domain family, member 2 2
Search outside databases for aliases for LARP2 genePrevious GC identifer: GC04P129341
Summaries for LARP2 (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
EntrezGene summary for LARP2 : This gene encodes a protein containing domains found in the La related protein of Drosophilamelanogaster. La motif-containing proteins are thought to be RNA-binding proteins, where the Lamotif and adjacent amino acids fold into an RNA recognition motif. The La motif is also found inproteins unrelated to the La protein. Alternative splicing has been observed at this locus andthree variants, encoding distinct isoforms, are described. Additional splice variation has beenidentified but the full-length nature of these transcripts has not been determined. [provided byRefSeq]
Genomic Location for LARP2
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
SABiosciences )About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the LARP2 gene Entrez Gene cytogenetic band: 4q28.2 Ensembl cytogenetic band: 4q28.2 HGNC cytogenetic band: 4q28.2 LARP2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 4 GeneLoc Exon Structure
GeneLoc location for GC04P129201:
(about GC identifiers )
Start:
129,201,953 bp from pter
End:
129,362,995 bp from pter
Size:
161,043 bases
Orientation:
plus strand
RefSeq DNA sequence: NC_000004.10 NT_016354.18 Proteins for LARP2
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
UniProtKB/Swiss-Prot: LARP2_HUMAN, Q659C4 (See
protein sequence )Recommended Name: La-related protein 2 Size : 914 amino acids; 105322 Da
Sequence caution : Sequence=AAH50654.1; Type=Erroneous initiation; Note=Translation N-terminallyextended; Sequence=AAH50654.1; Type=Frameshift; Positions=753; Sequence=BAB15679.1;Type=Frameshift; Positions=721; Sequence=CAH56379.1; Type=Frameshift; Positions=113;
Secondary accessions : Q2YDB6 Q4W599 Q4W5B2 Q659A0 Q6P5X2 Q7Z3F7 Q86VK7 Q8N6F4 Q8N7H4 Q8NAF2 Q9H5E7Q9NW12 Alternative splicing : 9 isoforms : Q659C4-1 Q659C4-2 Q659C4-3 Q659C4-4 Q659C4-5 Q659C4-6 Q659C4-7 Q659C4-8 Q659C4-9
Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins (3 alternative transcripts):
NP_060548.2 NP_115615.2 NP_835144.1 ENSEMBL proteins: ENSP00000346444 ENSP00000264584 ENSP00000377829 ENSP00000321997 Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells Antibodies for LARP2: Assays for LARP2:
Protein
Domains/ Families for LARP2(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Graphical View of Domain Structure for InterPro Entry Q659C4 ProtoNet protein and cluster: Q659C4
UniProtKB/Swiss-Prot: LARP2_HUMAN, Q659C4 Similarity : Belongs to the LARP familySimilarity : Contains 1 HTH La-type RNA-binding domain
Gene Function for LARP2
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
from Invitrogen ,
Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3 ): NM_018078 Applied Biosystems Silencer ® siRNAs for LARP2 Sigma-Aldrich siRNA for LARP2 Sigma-Aldrich shRNA for LARP2 Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 3 ): NM_018078                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 3 ): NM_018078                                  untagged cDNA clones in CMV expression vector (see all 3 ): NM_018078  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_018078 1 Gene Ontology (GO) molecular function term (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0003723 RNA binding
IEA --
About this table
Pathways & Interactions for LARP2
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
--
Drugs & Compounds for LARP2 (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Browse Tocris compounds for LARP2
Transcripts for LARP2(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
Abnova ,
siRNAs from Applied Biosystems ,
Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
Tagged/untagged cDNA clones from
OriGene , Expression Assays from Applied Biosystems )About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3 ): NM_018078 Sigma-Aldrich siRNA for LARP2 Sigma-Aldrich shRNA for LARP2 Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_018078 NM_032239 NM_178043
REFSEQ mRNAs for LARP2 gene (3 alternative transcripts): NM_018078.2 NM_032239.2 NM_178043.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_018078 NM_032239 NM_178043
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3 ): NM_018078                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 3 ): NM_018078                                  untagged cDNA clones in CMV expression vector (see all 3 ): NM_018078  
Additional cDNA sequence: AK001240.1 AK027164.1 AK092764.1 AK098437.1 AK310421.1 AL137759.1 AL832170.1 BC002840.1 BC018794.1 BC030516.1 BC050654.1 BC062606.1 BC110300.1 BX537937.1
23 DOTS entries : DT.92437998 DT.40244678 DT.312719 DT.75102991 DT.100677870 DT.100815009 DT.101980003 DT.92437999 DT.121229770 DT.70100606 DT.100815013 DT.100815015 DT.434459 DT.121229787 DT.121229797 DT.121229803 DT.121229810 DT.86821135 DT.91649312 DT.91774935 DT.92438002 DT.95366387 DT.99980326
24/194 AceView cDNA sequences (see all 194
):BM995827 BG565906 BU189933 AA927790 AI270097 AW264125 W74420 AA278959 AI767732 BG184686 BC030516 BG213124 CF528630 AI095346 BG191369 BM129812 AI222996 AW675315 BM698505 BX956784 BM904233 BU676813 AA781270 AA382919
highest scoring ESTs for LARP2 :AI207757 AI806546 AA278485 AA382919 AA604704 AI738989 AI767732 AI873450 AK027164 AK098437
Unigene Cluster for LARP2: La ribonucleoprotein domain family, member 2 Hs.657067 [show with all ESTs ] Unigene Representative Sequence: NM_018078 GeneLoc Exon Structure 5/6 Alternative Splicing Database (ASD) splice patterns (SP) for LARP2 (see all 6
) ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 SP1 :                                   -       SP2 :                                         SP3 :                                         SP4 :                               -           SP5 :                   -                      
About this scheme ECgene alternative splicing isoforms for LARP2 4 Ensembl transcripts including schematic representations : ENST00000354456
ENST00000264584
ENST00000394288
ENST00000326639
Expression for LARP2
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
LARP2 expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for LARP2 1 / 2 / 3
13 probe-sets matching LARP2 gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: --SOURCE GeneReport for Unigene cluster: Hs.657067
Orthologs for LARP2
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Orthologs for LARP2 gene from 5/11 species (see all 11
)
Organism
Gene
Locus
Description
Human Similarity
NCBI accessions
dog (Canis familiaris)
LARP21
--
La ribonucleoprotein domain family, member 2
93.49(n) 92.01(a)
476085 XM_533293.2 XP_533293.2
chimpanzee (Pan troglodytes)
LARP21
--
La ribonucleoprotein domain family, member 2
99.56(n) 99.23(a)
461482 XM_517433.2 XP_517433.2
mouse (Mus musculus)
Larp25
3
La ribonucleoprotein domain family, member 2
--
BG070579
chicken (Gallus gallus)
LARP21
--
La ribonucleoprotein domain family, member 2
75.77(n) 71.54(a)
422500 XM_420465.2 XP_420465.2
zebrafish (Danio rerio)
larp11
--
La ribonucleoprotein domain family, member 1
60.02(n) 61.29(a)
327175 XM_001920867.1 XP_001920902.1
About this table Species with no ortholog for LARP2 ENSEMBL Gene Tree for LARP2 Paralogs for LARP2 (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Paralogs for LARP2 gene LARP1 2
SNPs/Variants for LARP2 (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
HapMap Linkage Disequilibrium images for LARP2 (up to first 250kb)
Disorders & Mutations for LARP2
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
--
Medical News for LARP2 (Possibly Related Articles in
Doctor's Guide )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
--
Publications for LARP2 (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
7 PubMed articles for LARP2 gene :
Search for LARP2
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Genome Databases showing LARP2
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Other Databases showing LARP2
(According to HUGE )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
--
Specialized Databases showing LARP2 (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
-- Services for LARP2 (Reagents available from Applied Biosystems , Antibodies and assays by Cell
Signaling Technology , Abcam , Novus Biologicals ,Sigma-Aldrich , R&D Systems , Millipore , Abnova , and/or Invitrogen , Clones available from OriGene ,and/or Invitrogen , Drugs and/or compounds by Sigma-Aldrich , Enzo Life Sciences , and/or Tocris Bioscience )About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Products for LARP2:
Search Tocris compounds for LARP2
Jump to Section...
Aliases for LARP2
Databases for LARP2
Disorders for LARP2
Domains/Families for LARP2
Drugs/Compounds for LARP2
Expression for LARP2
Function for LARP2
Location for LARP2
Medical News for LARP2
Orthologs for LARP2
Paralogs for LARP2
Pathways/Interactions for LARP2
Proteins for LARP2
Publications for LARP2
SNPs for LARP2
Search Box for LARP2
Services for LARP2
Summaries for LARP2
Technologies for LARP2
Transcripts for LARP2
TOP
BOTTOM
GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009