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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

LAMP3 Gene

protein-coding GIFtS: 57
GCID: GC03M182840

lysosomal-associated membrane protein 3

Explore 28 diseases affiliated with
LAMP3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Lysosomal-Associated Membrane Protein 3¹ ² ³		LAMP-3² ³
DCLAMP¹ ² ³ ⁵		DC LAMP² ³
TSC403¹ ² ³		DC-Lysosome-Associated Membrane Glycoprotein² ³
CD208¹ ²		Lysosome-Associated Membrane Glycoprotein 3²
DC-LAMP¹ ²		CD208 Antigen³
LAMP¹ ²		Protein TSC403³

External Ids:	HGNC: 14582¹	Entrez Gene: 27074²	Ensembl: ENSG00000078081⁷	OMIM: 605883⁵	UniProtKB: Q9UQV4³

Export aliases for LAMP3 gene to outside databases

Previous GC identifers: GC03M179608 GC03M183695 GC03M184242 GC03M184160 GC03M184322 GC03M180244

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for LAMP3:

Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and

differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses

(summary by de Saint-Vis et al., 1998 (PubMed 9768752)).(supplied by OMIM, Dec 2010)

UniProtKB/Swiss-Prot: LAMP3_HUMAN, Q9UQV4

Function: May play a role in dendritic cell function and in adaptive immunity

Gene Wiki entry for LAMP3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000003.11 NC_018914.1 NT_005612.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the LAMP3 gene promoter:
TBP Sox5 p53 HNF-1 NCX/Ncx SEF-1 (1) ZID IRF-1 LCR-F1 HNF-1A
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: LAMP3 promoter sequence

Search SABiosciences Chromatin IP Primers for LAMP3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LAMP3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q26.3-q27 Ensembl cytogenetic band: 3q27.1 HGNC cytogenetic band: 3q26.3-q27

LAMP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LAMP3 gene location

GeneLoc information about chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03M182840: view genomic region (about GC identifiers)

Start:	182,840,001 bp from pter	End:	182,881,627 bp from pter
Size:	41,627 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: LAMP3_HUMAN, Q9UQV4 (See protein sequence)

Recommended Name: Lysosome-associated membrane glycoprotein 3 precursor

Size: 416 amino acids; 44346 Da

Subunit: Monomer

Subcellular location: Lysosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass

type I membrane protein. Note=During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II

compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3. Detected on lysosomes in mature dendritic cells

Developmental stage: Up-regulated during dendritic cell maturation

1 PDB 3D structure from and Proteopedia for LAMP3:

4AKM (3D)

Secondary accessions: D3DNS4 O94781 Q8NEC8

Explore the universe of human proteins at neXtProt for LAMP3: NX_Q9UQV4

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9UQV4

LAMP3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_055213.2

ENSEMBL proteins:

ENSP00000265598 ENSP00000418912 ENSP00000419059 ENSP00000420589

Human Recombinant Protein Products:

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	Browse ProSpec Recombinant Proteins
	Uscn Proteins for LAMP3

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005765	lysosomal membrane	IEA	--
GO:0016021	integral to membrane	IEA	--
GO:0097233	alveolar lamellar body membrane	IEA	--

LAMP3 for ontologies About GeneDecksing

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	Search ThermoFisher Antibodies for LAMP3

Assay Products for LAMP3:

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	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for LAMP3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

LAMP3 for domains About GeneDecksing

1 InterPro domain/family:

IPR002000 Lysosome-assoc_membr_glycop

Graphical View of Domain Structure for InterPro Entry Q9UQV4

ProtoNet protein and cluster: Q9UQV4

UniProtKB/Swiss-Prot: LAMP3_HUMAN, Q9UQV4

Similarity: Belongs to the LAMP family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: LAMP3_HUMAN, Q9UQV4

Function: May play a role in dendritic cell function and in adaptive immunity

miRNA Products:		OriGene 3'-UTR Clone: LAMP3 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LAMP3
		4 QIAGEN miScript miRNA Assays for microRNAs that regulate LAMP3:
		hsa-miR-382 hsa-miR-3163 hsa-miR-149 hsa-miR-516b
		SwitchGear 3'UTR luciferase reporter plasmid: LAMP3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for LAMP3 (see all 7) OriGene shRNA RFP: LAMP3 OriGene siRNA: LAMP3
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Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for LAMP3

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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for LAMP3
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LAMP3

1 GenomeRNAi human phenotype for LAMP3:

Increased gamma-H2AX phosphory

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Lysosome

Lysosome

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 Kegg Pathway (Kegg details for LAMP3):

Lysosome

LAMP3 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for LAMP3

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for LAMP3 (Q9UQV4^{2, 3} ENSP00000265598⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ABCA3	Q99758²^,³, ENSP00000301732⁴	MINT-7996593 MINT-7996607 MINT-7996380 I2D: score=1 STRING: ENSP00000301732
SGTB	ENSP00000370395⁴	STRING: ENSP00000370395

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008283	cell proliferation	TAS	9721848

LAMP3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

LAMP3 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for LAMP3
2 Novoseek chemical compound relationships for LAMP3 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
glycogen	5.33	1	16899762 (1)
histamine	1.58	2	15675967 (2)

Search CenterWatch for drugs/clinical trials and news about LAMP3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for LAMP3 gene:

NM_014398.3

Unigene Cluster for LAMP3:

Lysosomal-associated membrane protein 3

Hs.518448 [show with all ESTs]

Unigene Representative Sequence: NM_014398

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000265598(uc003flh.4) ENST00000466939 ENST00000476015 ENST00000470251

ENST00000486686

miRNA Products:		OriGene 3'-UTR Clone: LAMP3 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LAMP3
		4 QIAGEN miScript miRNA Assays for microRNAs that regulate LAMP3:
		hsa-miR-382 hsa-miR-3163 hsa-miR-149 hsa-miR-516b
		SwitchGear 3'UTR luciferase reporter plasmid: LAMP3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for LAMP3 (see all 7) OriGene shRNA RFP: LAMP3 OriGene siRNA: LAMP3
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Additional cDNA sequence:

AB013924.1 AJ005766.1 AK302894.1 AK313172.1 BC032940.2

5 DOTS entries:

DT.312133 DT.100754307 DT.95270377 DT.75135130 DT.95208861

24/58 AceView cDNA sequences (see all 58):

BX116004 BQ013434 AA314075 BQ029162 AA382983 BM985389 BM758382 NM_014398

AI304250 T92658 AI285648 AA416838 BF061943 BI822806 AW014530 BM997858

H65113 AB013924 BU687869 AA304148 T61471 BM996446 AW274149 BI818999

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for LAMP3 About this scheme

ExUns:	1a	·	1b	^	2	^	3a	·	3b	·	3c	·	3d	^	4	^	5	^	6	^	7
SP1:
SP2:
SP3:
SP4:					-

ECgene alternative splicing isoforms for LAMP3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

LAMP3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTTTCCTTA

About this image

LAMP3 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

Alveolar type II cells (Derivation of mature...)

Lung

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See LAMP3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for LAMP3

SOURCE GeneReport for Unigene cluster: Hs.518448

UniProtKB/Swiss-Prot: LAMP3_HUMAN, Q9UQV4

Tissue specificity: Detected in tonsil interdigitating dendritic cells, in spleen, lymph node, Peyer's patches in the

small instestine, in thymus medulla and in B cells (at protein level). Expressed in lymphoid organs and dendritic

cells. Expressed in lung. Up-regulated in carcinomas of the esophagus, colon, rectum, ureter, stomach, breast,

fallopian tube, thyroid and parotid tissues

SABiosciences Custom PCR Arrays for LAMP3

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LAMP3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for LAMP3 gene from 5/17 species (see all 17) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Lamp3^{1 , 5}	lysosomal-associated membrane protein 3^{1, 5}	73.02(n)¹ 54.46(a)¹		16 (12.17 cM)⁵ 239739¹ NM_177356.3¹ NP_796330.2¹ 19653381⁵
chicken (Gallus gallus)	Aves	LAMP3¹	lysosomal-associated membrane protein 3	47.96(n) 35.82(a)		424961 NM_001146132.1 NP_001139604.1
lizard (Anolis carolinensis)	Reptilia	LAMP3⁶	--	34(a)	1 ↔ 1	3(162317-168189)
zebrafish (Danio rerio)	Actinopterygii	LOC100003043¹	lysosome-associated membrane glycoprotein 1-like	48.11(n) 30.77(a)		100003043 XM_001342652.3 XP_001342688.2
fruit fly (Drosophila melanogaster)	Insecta	Lamp1⁶	Lamp1	18(a)	1 → many	2L(21573389-21577103)

ENSEMBL Gene Tree for LAMP3 (if available)
TreeFam Gene Tree for LAMP3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for LAMP3 gene

LAMP1² CD68² LAMP2²

LAMP3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 3 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs604712^1,2	C,A,H,	--	182839512(-)	`ACTCCA/GTCTCT`	1	--	ds500¹		5		NA	10
rs115039515^1,2		--	182839619(+)	`TCCCAG/ACCCTC`	1	--	ds500¹		1		WA	118
rs185984430^1,2		--	182839681(+)	`ATCTCA/GGCTCC`	1	--	ds500¹		0	--	--	--	--
rs112336937^1,2		--	182839766(+)	`TTAAGC/TAAACT`	1	--	ds500¹		1		CSA	2
rs78806429^1,2		--	182839895(+)	`AATTAT/CAGAAA`	1	--	ds500¹		1		NA	120
rs12353^1,2		--	182840022(-)	`TTTTGT/CAATAA`	1	--	ut3¹		2		MN NA	186
rs2314416^1,2	H	--	182840151(+)	`CTTGAC/TTAAGA`	1	--	ut3¹ ese³		3		EA NS	298
rs73886231^1,2	C,	--	182840224(+)	`AAAAAC/ACAGCA`	1	--	ut3¹		1		WA	2
rs183246801^1,2		--	182840250(+)	`GCAGGA/CTGCTC`	1	--	ut3¹		0	--	--	--	--
rs141496275^1,2		--	182840324(+)	`GATGGA/GGCTAT`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for LAMP3 (182840001 - 182881627 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for LAMP3: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LAMP3

DNA2.0 Custom Variant and Variant Library Synthesis for LAMP3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

LAMP3 for disorders           About GeneDecksing

OMIM gene information: 605883    OMIM disorders: --

20/28 diseases for LAMP3 (see all 28):    About MalaCards

oculocutaneous albinism bipolar affective disorder lupus erythematosus myocardial infarction

acute myocardial infarction systemic lupus erythematosus albinism gaucher's disease

bipolar disorder rheumatoid arthritis multiple sclerosis dermatomyositis

hemangioma parkinson's disease copd pertussis

cervical cancer cervicitis arthritis influenza

5 Novoseek disease relationships for LAMP3 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
necrosis	6.43	1	11104808 (1)
tumors	5.69	5	11104808 (1), 19244125 (1), 14982840 (1), 17127298 (1)
lupus erythematosus systemic	1.54	1	7920621 (1)
aids	0	1	12406887 (1)
cancer	0	4	16204031 (2), 11485903 (1)

Human Genome Epidemiology (HuGE) Navigator: LAMP3 (6 documents)

Export disorders for LAMP3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for LAMP3 gene, integrated from 9 sources (see all 84):
(articles sorted by number of sources associating them with LAMP3)

Utopia: connect your pdf to the dynamic
world of online information

Isolation and characterization of a novel human lung-specific gene homologous to lysosomal membrane glycoprotein 1 and 2; significantly increased expression in cancers of various tissues. (PubMed id 9721848)^{1, 2, 3} Ozaki K.... Nakamura Y. (1998)
A novel lysosome-associated membrane glycoprotein, DC-LAMP, induced upon DC maturation, is transiently expressed in MHC class II compartment. (PubMed id 9768752)^{1, 2, 9} de Saint-Vis B.M.... Lebecque S. (1998)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Overexpression of LAMP3/TSC403/DC-LAMP promotes metastasis in uterine cervical cancer. (PubMed id 16204031)^{1, 9} Kanao H....Murata Y. (2005)
Increased expression of CD208 (DC-LAMP) in epidermal keratinocytes of psoriatic lesions. (PubMed id 19335688)^{1, 9} Higaki M....Kawashima M. (2009)
Dendritic cell-lysosomal-associated membrane protein (LAMP) and LAMP-1-HIV-1 gag chimeras have distinct cellular trafficking pathways and prime T and B cell responses to a diverse repertoire of epitopes. (PubMed id 16887987)^{1, 9} Arruda L.B....Marques E.T. (2006)
Human dendritic cell lysosome-associated membrane protein expressed in lung type II pneumocytes. (PubMed id 15111122)^{1, 9} Akasaki K....August J.T. (2004)
Crystal structure of the conserved domain of the DC lysosomal associated membrane protein: implications for the lysosomal glycocalyx. (PubMed id 22809326)² Wilke S.... Bussow K. (2012)
Web-based genome-wide association study identifies tw o novel loci and a substantial genetic component for Parkinson's disease. (PubMed id 21738487)¹ Do C.B....Eriksson N. (2011)
Hypoxic regulation and prognostic value of LAMP3 expression in breast cancer. (PubMed id 21319150)¹ Nagelkerke A....Span P.N. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 27074	HGNC: 14582	AceView: LAMP3	Ensembl:ENSG00000078081	euGenes: HUgn27074
ECgene: LAMP3	Kegg: 27074	H-InvDB: LAMP3

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for LAMP3	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for LAMP3	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for LAMP3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for LAMP3 gene:
Search GeneIP for patents involving LAMP3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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lysosomal-associated membrane protein 3

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LAMP3 Gene

lysosomal-associated membrane protein 3

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for LAMP3 gene

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for LAMP3 gene

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for LAMP3 gene

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for LAMP3 gene

Expression
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for LAMP3 gene

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for LAMP3 gene

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Intellectual Property
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