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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

LAMP3 Gene

protein-coding   GIFtS: 61
GCID: GC03M182840

Lysosomal-Associated Membrane Protein 3

Alzheimer's & Parkinson's Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Lysosomal-Associated Membrane Protein 31 2 3     CD2082
DCLAMP2 3 5     DC-LAMP2
LAMP-32 3     LAMP2
TSC4032 3     Lysosome-Associated Membrane Glycoprotein 32
DC LAMP2 3     CD208 Antigen3
DC-Lysosome-Associated Membrane Glycoprotein2 3     Protein TSC4033

External Ids:    HGNC: 145821   Entrez Gene: 270742   Ensembl: ENSG000000780817   OMIM: 6058835   UniProtKB: Q9UQV43   

Export aliases for LAMP3 gene to outside databases

Previous GC identifers: GC03M179608 GC03M183695 GC03M184242 GC03M184160 GC03M184322 GC03M180244


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for LAMP3 Gene:
Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and
differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell
responses (summary by de Saint-Vis et al., 1998 (PubMed 9768752)).(supplied by OMIM, Dec 2010)

GeneCards Summary for LAMP3 Gene: 
LAMP3 (lysosomal-associated membrane protein 3) is a protein-coding gene. Diseases associated with LAMP3 include oculocutaneous albinism, and gaucher's disease. An important paralog of this gene is LAMP1.

UniProtKB/Swiss-Prot: LAMP3_HUMAN, Q9UQV4
Function: May play a role in dendritic cell function and in adaptive immunity

Gene Wiki entry for LAMP3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_005612.16  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the LAMP3 gene promoter:
         TBP   Sox5   p53   HNF-1   NCX/Ncx   SEF-1 (1)   ZID   IRF-1   LCR-F1   HNF-1A   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidLAMP3 promoter sequence
   Search SABiosciences Chromatin IP Primers for LAMP3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LAMP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q26.3-q27   Ensembl cytogenetic band:  3q27.1   HGNC cytogenetic band: 3q26.3-q27

LAMP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LAMP3 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M182840:  view genomic region     (about GC identifiers)

Start:
182,840,001 bp from pter      End:
182,881,627 bp from pter
Size:
41,627 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: LAMP3_HUMAN, Q9UQV4 (See protein sequence)
Recommended Name: Lysosome-associated membrane glycoprotein 3 precursor  
Size: 416 amino acids; 44346 Da
Subunit: Monomer
Subcellular location: Lysosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane;
Single-pass type I membrane protein. Note=During dendritic cell maturation, detected on cytoplasmic vesicles (the
MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3. Detected on lysosomes in mature
dendritic cells
Developmental stage: Up-regulated during dendritic cell maturation
1 PDB 3D structure from and Proteopedia for LAMP3:
4AKM (3D)    
Secondary accessions: D3DNS4 O94781 Q8NEC8

Explore the universe of human proteins at neXtProt for LAMP3: NX_Q9UQV4

Explore proteomics data for LAMP3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UQV4

  • LAMP3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    LAMP3 Protein Expression
    REFSEQ proteins: NP_055213.2  
    ENSEMBL proteins: 
     ENSP00000265598   ENSP00000418912   ENSP00000419059   ENSP00000420589  

    Human Recombinant Protein Products for LAMP3: 
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    Novus Biologicals LAMP3 Protein
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    Sino Biological Recombinant Protein for LAMP3
    Sino Biological Cell Lysate for LAMP3 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for LAMP3 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005765lysosomal membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--
    GO:0097233alveolar lamellar body membrane IEA--

    LAMP3 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. ELISAs for LAMP3 
    Cloud-Clone Corp. CLIAs for LAMP3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CD: CD molecules

    1 InterPro protein domain:
     IPR002000 Lysosome-assoc_membr_glycop

    Graphical View of Domain Structure for InterPro Entry Q9UQV4

    ProtoNet protein and cluster: Q9UQV4

    UniProtKB/Swiss-Prot: LAMP3_HUMAN, Q9UQV4
    Similarity: Belongs to the LAMP family


    LAMP3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: LAMP3_HUMAN, Q9UQV4
    Function: May play a role in dendritic cell function and in adaptive immunity

    Phenotypes:
         1 GenomeRNAi human phenotype for LAMP3:

     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for LAMP3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for LAMP3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for LAMP3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for LAMP3 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LAMP3
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate LAMP3:
    hsa-miR-382 hsa-miR-3163 hsa-miR-149 hsa-miR-516b
    SwitchGear 3'UTR luciferase reporter plasmidLAMP3 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LAMP3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for LAMP3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Lysosome
    Lysosome

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1         Kegg Pathway  (Kegg details for LAMP3):
        Lysosome


    LAMP3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for LAMP3

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for LAMP3 (Q9UQV42, 3 ENSP000002655984) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABCA3Q997582, 3, ENSP000003017324MINT-7996593 MINT-7996607 MINT-7996380 I2D: score=1 STRING: ENSP00000301732
    SGTBENSP000003703954STRING: ENSP00000370395
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008283cell proliferation TAS9721848

    LAMP3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    LAMP3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for LAMP3

    2 Novoseek inferred chemical compound relationships for LAMP3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    glycogen 5.33 1 16899762 (1)
    histamine 1.58 2 15675967 (2)

    Search CenterWatch for drugs/clinical trials and news about LAMP3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for LAMP3 gene: 
    NM_014398.3  

    Unigene Cluster for LAMP3:

    Lysosomal-associated membrane protein 3
    Hs.518448  [show with all ESTs]
    Unigene Representative Sequence: NM_014398
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000265598(uc003flh.4) ENST00000466939 ENST00000476015 ENST00000470251
    ENST00000486686

    miRNA
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    4 QIAGEN miScript miRNA Assays for microRNAs that regulate LAMP3:
    hsa-miR-382 hsa-miR-3163 hsa-miR-149 hsa-miR-516b
    SwitchGear 3'UTR luciferase reporter plasmidLAMP3 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    Sirion Biotech Customized lentivirus for stable overexpression of LAMP3 
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LAMP3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LAMP3

    Additional mRNA sequence: 

    AB013924.1 AJ005766.1 AK302894.1 AK313172.1 BC032940.2 

    5 DOTS entries:

    DT.312133  DT.100754307  DT.95270377  DT.75135130  DT.95208861 

    24/58 AceView cDNA sequences (see all 58):

    BM758382 BX116004 BM997858 AI285648 BF061943 AA416838 AA314075 NM_014398 
    BM985389 BQ029162 BQ013434 T92658 AW014530 BI822806 AI304250 AA382983 
    AW274149 BU678297 AJ005766 BG771499 BI818999 BC032940 AA416689 AB013924 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for LAMP3    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5 ^ 6 ^ 7
    SP1:                                                                  
    SP2:                                                                  
    SP3:                                                                  
    SP4:              -                                                   


    ECgene alternative splicing isoforms for LAMP3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    LAMP3 expression in normal human tissues (normalized intensities)      LAMP3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTTTCCTTA
    LAMP3 Expression
    About this image


    LAMP3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/14 selected tissues (see all 14) fully expand
     
     Lymph (Cardiovascular System)    fully expand to see all 3 entries
             lymph node ; non-germinal center cells   
             Lymphnode   
     
     Lung (Respiratory System)    fully expand to see all 2 entries
             lung ; pneumocytes   
     
     Smooth Muscle (Muscoskeletal System)
             Human Bronchial Smooth Muscle Cells (HBSM)   
     
     Gut Tube (Gastrointestinal Tract)
             Definitive endoderm-like cells ( A scalable, suspension protocol for derivation of...
     
     Lower Urinary Tract (Urinary System)
             Human Urothelial Cells (HUC)   

    See LAMP3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for LAMP3

    SOURCE GeneReport for Unigene cluster: Hs.518448

    UniProtKB/Swiss-Prot: LAMP3_HUMAN, Q9UQV4
    Tissue specificity: Detected in tonsil interdigitating dendritic cells, in spleen, lymph node, Peyer's patches in
    the small instestine, in thymus medulla and in B cells (at protein level). Expressed in lymphoid organs and
    dendritic cells. Expressed in lung. Up-regulated in carcinomas of the esophagus, colon, rectum, ureter, stomach,
    breast, fallopian tube, thyroid and parotid tissues

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LAMP3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for LAMP3 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Lamp31 , 5 lysosomal-associated membrane protein 31, 5 73.02(n)1
    54.46(a)1
      16 (12.17 cM)5
    2397391  NM_177356.31  NP_796330.21 
     196533815 
    chicken
    (Gallus gallus)
    Aves LAMP31 lysosomal-associated membrane protein 3 47.96(n)
    35.82(a)
      424961  NM_001146132.1  NP_001139604.1 
    lizard
    (Anolis carolinensis)
    Reptilia LAMP36
    Uncharacterized protein
    26(a)
    1 ↔ 1
    3(160686-171150)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1000030431 lysosome-associated membrane glycoprotein 1-like 48.11(n)
    30.77(a)
      100003043  XM_001342652.3  XP_001342688.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Lamp16
    Lamp1
    18(a)
    1 → many
    2L(21573389-21577103)


    ENSEMBL Gene Tree for LAMP3 (if available)
    TreeFam Gene Tree for LAMP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for LAMP3 gene
    LAMP12  CD682  LAMP22  

    LAMP3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/989 SNPs in LAMP3 are shown (see all 989)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs38362971,2
    C--182715080(+) AAAAA-/A/AA  
            
    TGTAA
    1 -- int1 trp30--------
    rs6047121,2
    C,A,H--182839512(-) actccA/Gtctct 1 -- ds50015Minor allele frequency- G:0.00NA 10
    rs1150395151,2
    F--182839619(+) TCCCAG/ACCCTC 1 -- ds50011Minor allele frequency- A:0.01WA 118
    rs1859844301,2
    --182839681(+) ATCTCA/GGCTCC 1 -- ds50010--------
    rs1123369371,2
    C,F--182839766(+) TTAAGC/TAAACT 1 -- ds50011Minor allele frequency- T:0.50CSA 2
    rs788064291,2
    F--182839895(+) AATTAT/CAGAAA 1 -- ds50011Minor allele frequency- C:0.01NA 120
    rs123531,2
    F--182840022(-) TTTTGT/CAATAA 1 -- ut312Minor allele frequency- C:0.00MN NA 186
    rs23144161,2
    H--182840151(+) CTTGAC/TTAAGA 1 -- ut31 ese33Minor allele frequency- T:0.00EA NS 298
    rs738862311,2
    C,F--182840224(+) AAAAAC/ACAGCA 1 -- ut311Minor allele frequency- A:0.50WA 2
    rs1832468011,2
    --182840250(+) GCAGGA/CTGCTC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for LAMP3 (182840001 - 182881627 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for LAMP3:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv508970CNV Insertion20534489
    nsv507143CNV Insertion20534489

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing LAMP3
    DNA2.0 Custom Variant and Variant Library Synthesis for LAMP3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605883    OMIM disorders: --

    20/26 diseases for LAMP3 (see all 26):    About MalaCards
    oculocutaneous albinism    gaucher's disease    albinism    dermatomyositis
    hemangioma    acute myocardial infarction    pertussis    bipolar disorder
    lupus erythematosus    myocardial infarction    tonsillitis    parkinson's disease
    influenza    cervical cancer    pneumonia    multiple sclerosis
    systemic lupus erythematosus    cervicitis    rheumatoid arthritis    arthritis


    LAMP3 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    5 Novoseek inferred disease relationships for LAMP3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    necrosis 6.43 1 11104808 (1)
    tumors 5.69 5 11104808 (1), 19244125 (1), 14982840 (1), 17127298 (1)
    lupus erythematosus systemic 1.54 1 7920621 (1)
    aids 0 1 12406887 (1)
    cancer 0 4 16204031 (2), 11485903 (1)

    Genetic Association Database (GAD): LAMP3
    Human Genome Epidemiology (HuGE) Navigator: LAMP3 (6 documents)

    Export disorders for LAMP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for LAMP3 gene, integrated from 9 sources (see all 85):
    (articles sorted by number of sources associating them with LAMP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation and characterization of a novel human lung-specific gene homologous to lysosomal membrane glycoprotein 1 and 2; significantly increased expression in cancers of various tissues. (PubMed id 9721848)1, 2, 3 Ozaki K.... Nakamura Y. (1998)
    2. A novel lysosome-associated membrane glycoprotein, DC-LAMP, induced upon DC maturation, is transiently expressed in MHC class II compartment. (PubMed id 9768752)1, 2, 9 de Saint-Vis B.M.... Lebecque S. (1998)
    3. Crystal structure of the conserved domain of the DC lysosomal associated membrane protein: implications for the lysosomal glycocalyx. (PubMed id 22809326)1, 2 Wilke S.... Bussow K. (2012)
    4. Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide associat ion studies. (PubMed id 21292315)1, 4  ....Wood N.W. (2011)
    5. Propensity score-based nonparametric test revealing ge netic variants underlying bipolar disorder. (PubMed id 21254220)1, 4 Jiang Y. and Zhang H. (2011)
    6. Family-based association study for bipolar affective disorder. (PubMed id 20414141)1, 4 Secolin R....Lopes-Cendes I. (2010)
    7. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    8. Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort. (PubMed id 19308021)1, 4 Ollila H.M....Paunio T. (2009)
    9. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. (PubMed id 17554300)1, 4  . (2007)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 27074 HGNC: 14582 AceView: LAMP3 Ensembl:ENSG00000078081 euGenes: HUgn27074
    ECgene: LAMP3 Kegg: 27074 H-InvDB: LAMP3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for LAMP3 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for LAMP3 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for LAMP3 gene:
    Search GeneIP for patents involving LAMP3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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