Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



LAMP2 Gene

protein-coding   GIFtS: 71
GCID: GC0XM119560

Lysosomal-Associated Membrane Protein 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Lysosomal-Associated Membrane Protein 21 2     CD107b2
LAMP-22 3     Lysosome-Associated Membrane Glycoprotein 22
CD107 Antigen-Like Family Member B2 3     CD107b Antigen3
LAMPB2 5     Lysosome-Associated Membrane Protein 23
LGP1102 5     

External Ids:    HGNC: 65011   Entrez Gene: 39202   Ensembl: ENSG000000058937   OMIM: 3090605   UniProtKB: P134733   

Export aliases for LAMP2 gene to outside databases

Previous GC identifers: GC0XM114382 GC0XM116550 GC0XM117540 GC0XM118318 GC0XM119346 GC0XM119448 GC0XM109011


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for LAMP2 Gene:
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides
selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the
protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple
transcript variants encoding distinct proteins. (provided by RefSeq, Jul 2008)

GeneCards Summary for LAMP2 Gene:
LAMP2 (lysosomal-associated membrane protein 2) is a protein-coding gene. Diseases associated with LAMP2 include danon disease, and vacuolar myopathy. An important paralog of this gene is LAMP1.

UniProtKB/Swiss-Prot: LAMP2_HUMAN, P13473
Function: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from
autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface
(plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of
methylating mutagens

Gene Wiki entry for LAMP2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000023.11  NC_018934.2  NT_011786.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the LAMP2 gene promoter:
         TBP   RFX1   AP-2alpha isoform 3   Nkx2-2   NCX/Ncx   AP-2alpha isoform 2   TFIID   AP-2alpha isoform 4   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidLAMP2 promoter sequence
   Search Chromatin IP Primers for LAMP2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat LAMP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq24   Ensembl cytogenetic band:  Xq24   HGNC cytogenetic band: Xq24-q25

LAMP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LAMP2 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM119560:  view genomic region     (about GC identifiers)

Start:
119,560,003 bp from pter      End:
119,603,220 bp from pter
Size:
43,218 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: LAMP2_HUMAN, P13473 (See protein sequence)
Recommended Name: Lysosome-associated membrane glycoprotein 2 precursor  
Size: 410 amino acids; 44961 Da
Secondary accessions: A8K4X5 D3DTF0 Q16641 Q6Q3G8 Q96J30 Q99534 Q9UD93
Alternative splicing: 3 isoforms:  P13473-1   P13473-2   P13473-3   

Explore the universe of human proteins at neXtProt for LAMP2: NX_P13473

Explore proteomics data for LAMP2 at MOPED

Post-translational modifications: 

  • O- and N-glycosylated; some of the 16 N-linked glycans are polylactosaminoglycans1
  • Glycosylation2 at Asn32, Asn38, Asn49, Asn58, Asn75, Asn101, Asn123, Asn179, Ser195, Thr196,
                                 Thr200, Thr203, Thr204, Ser207, Thr209, Thr210, Thr211, Thr213, Asn229, Asn242 (see all 26)
  • Modification sites at PhosphoSitePlus

  • See LAMP2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001116078.1  NP_002285.1  NP_054701.1  

    ENSEMBL proteins: 
     ENSP00000408411   ENSP00000200639   ENSP00000431526   ENSP00000360386   ENSP00000440506  
     ENSP00000440479  
    Reactome Protein details: P13473

    LAMP2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for LAMP2 (LAMP2/CD107b)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Proteins for LAMP2
    OriGene Protein Over-expression Lysate for LAMP2
    OriGene MassSpec for LAMP2
    OriGene Custom Protein Services for LAMP2
    GenScript Custom Purified and Recombinant Proteins Services for LAMP2
    Novus Biologicals LAMP2 Proteins
    Novus Biologicals LAMP2 Lysates
    Sino Biological Recombinant Protein for LAMP2
    Sino Biological Cell Lysate for LAMP2
    ProSpec Recombinant Protein for LAMP2
    Cloud-Clone Corp. Proteins for LAMP2

    LAMP2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for LAMP2 (LAMP2/CD107b)
    OriGene Antibodies for LAMP2
    OriGene Custom Antibody Services for LAMP2
    Novus Biologicals LAMP2 Antibodies
    Abcam antibodies for LAMP2
    Cloud-Clone Corp. Antibodies for LAMP2
    ThermoFisher Antibody for LAMP2
    LSBio Antibodies in human, mouse, rat for LAMP2

    LAMP2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for LAMP2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for LAMP2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for LAMP2
    Cloud-Clone Corp. CLIAs for LAMP2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    CD: CD molecules

    2 InterPro protein domains:
     IPR018134 LAMP_CS
     IPR002000 Lysosome-assoc_membr_glycop

    Graphical View of Domain Structure for InterPro Entry P13473

    ProtoNet protein and cluster: P13473

    1 Blocks protein domain: IPB002000 Lysosome-associated membrane glycoprotein (Lamp)/CD68

    UniProtKB/Swiss-Prot: LAMP2_HUMAN, P13473
    Similarity: Belongs to the LAMP family


    LAMP2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: LAMP2_HUMAN, P13473
    Function: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from
    autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface
    (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of
    methylating mutagens

         Genatlas biochemistry entry for LAMP2:
    lysosomal associated membrane protein 2

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0019899enzyme binding IPI--
         
    LAMP2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for LAMP2:
     Increased gamma-H2AX phosphory 

         13 MGI mutant phenotypes (inferred from 1 allele(MGI details for Lamp2):
     cardiovascular system  cellular  craniofacial  growth/size/body  hematopoietic system 
     homeostasis/metabolism  immune system  integument  mortality/aging  muscle 
     nervous system  reproductive system  skeleton 

    LAMP2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Lamp2tm1Psa for LAMP2

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for LAMP2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for LAMP2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for LAMP2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for LAMP2

    miRNA
    Products:
        
    miRTarBase miRNAs that target LAMP2:
    hsa-mir-21-5p (MIRT030821), hsa-mir-124-3p (MIRT022427), hsa-mir-16-5p (MIRT031571), hsa-mir-103a-3p (MIRT027054)

    Block miRNA regulation of human, mouse, rat LAMP2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate LAMP2 (see all 56):
    hsa-miR-140-5p hsa-miR-2052 hsa-miR-193a-3p hsa-let-7d hsa-miR-376b hsa-miR-15a hsa-miR-25 hsa-miR-3653
    SwitchGear 3'UTR luciferase reporter plasmidLAMP2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for LAMP2
    Predesigned siRNA for gene silencing in human, mouse, rat LAMP2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for LAMP2

    Clone
    Products:
         
    OriGene clones in human, mouse for LAMP2 (see all 18)
    OriGene ORF clones in mouse, rat for LAMP2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): LAMP2 (NM_013995)
    Sino Biological Human cDNA Clone for LAMP2
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LAMP2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LAMP2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for LAMP2
    Browse ESI BIO Cell Lines and PureStem Progenitors for LAMP2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LAMP2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    LAMP2_HUMAN, P13473: Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I
    membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=This protein shuttles between
    lysosomes, endosomes, and the plasma membrane
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endosome5
    lysosome5
    plasma membrane5
    vacuole5
    endoplasmic reticulum2
    extracellular2
    golgi apparatus2
    cytoskeleton1
    mitochondrion1

    Gene Ontology (GO): Selected cellular component terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005764lysosome IDA12536145
    GO:0005765lysosomal membrane IDA15297306
    GO:0005770late endosome IDA15229288
    GO:0005886plasma membrane TAS--
    GO:0016020membrane IDA15297306

    LAMP2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for LAMP2 About   (see all 6)  
    See pathways by source

    SuperPathContained pathways About
    1Response to elevated platelet cytosolic Ca2+
    Response to elevated platelet cytosolic Ca2+0.94
    Platelet degranulation0.94
    2Hemostasis
    Hemostasis0.43
    Platelet activation, signaling and aggregation0.43
    3Tuberculosis
    Tuberculosis
    4Senescence and Autophagy
    Senescence and Autophagy
    5Phagosome
    Phagosome

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for LAMP2
        Senescence and Autophagy


    1 Reactome Pathway for LAMP2
        Platelet degranulation


    3 Kegg Pathways  (Kegg details for LAMP2):
        Lysosome
    Phagosome
    Tuberculosis


    LAMP2 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for LAMP2
    Interactions:

        GeneGlobe Interaction Network for LAMP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for LAMP2 (P134732, 3 ENSP000004084114) via UniProtKB, MINT, STRING, and/or I2D (see all 37)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ADRB2P075502, 3, ENSP000003053724MINT-7291650 I2D: score=1 STRING: ENSP00000305372
    SOD1P004412, 3, ENSP000002701424MINT-8143734 I2D: score=1 STRING: ENSP00000270142
    ENSG00000206379O759553, ENSP000003728734I2D: score=1 STRING: ENSP00000372873
    ENSG00000232280O759553, ENSP000003914384I2D: score=1 STRING: ENSP00000391438
    FLOT1O759553, ENSP000003655694I2D: score=1 STRING: ENSP00000365569
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002576platelet degranulation TAS--
    GO:0007596blood coagulation TAS--
    GO:0030168platelet activation TAS--
    GO:0050821protein stabilization ISS--

    LAMP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for LAMP2

    6 Novoseek inferred chemical compound relationships for LAMP2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    mannose 6-phosphate 55 2 1845800 (1), 11404461 (1)
    n-acetyllactosamine 52.5 3 2243102 (1), 2243101 (1)
    glycogen 49.4 6 11552028 (1), 15907287 (1), 17642461 (1), 18691923 (1) (see all 5)
    sucrose 10.5 3 1845800 (1), 1520873 (1), 19679094 (1)
    dextran 9.77 1 11067894 (1)
    cholesterol 0 2 10666334 (1), 11032830 (1)



    LAMP2 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for LAMP2 gene (3 alternative transcripts): 
    NM_001122606.1  NM_002294.2  NM_013995.2  

    Unigene Cluster for LAMP2:

    Lysosomal-associated membrane protein 2
    Hs.496684  [show with all ESTs]
    Unigene Representative Sequence: NM_002294
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000434600(uc004est.4 uc004ess.4 uc011mtz.2) ENST00000200639
    ENST00000486593 ENST00000371335(uc011mua.1 uc010nqp.1) ENST00000538785
    ENST00000540603
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat LAMP2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate LAMP2 (see all 56):
    hsa-miR-140-5p hsa-miR-2052 hsa-miR-193a-3p hsa-let-7d hsa-miR-376b hsa-miR-15a hsa-miR-25 hsa-miR-3653
    SwitchGear 3'UTR luciferase reporter plasmidLAMP2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for LAMP2
    Predesigned siRNA for gene silencing in human, mouse, rat LAMP2
    Clone
    Products:
         
    OriGene clones in human, mouse for LAMP2 (see all 18)
    OriGene ORF clones in mouse, rat for LAMP2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): LAMP2 (NM_013995)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LAMP2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LAMP2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for LAMP2
    OriGene qSTAR qPCR primer pairs in human, mouse for LAMP2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat LAMP2
      QuantiTect SYBR Green Assays in human, mouse, rat LAMP2
      QuantiFast Probe-based Assays in human, mouse, rat LAMP2

    Additional mRNA sequence: 

    AK126232.1 AK291090.1 AK293931.1 AK295038.1 AK304405.1 AY561849.1 BC002965.1 BC040653.2 
    BX648255.1 J04183.1 S79873.1 U36336.1 X77196.1 

    Selected DOTS entries (see all 50):

    DT.92457710  DT.95371837  DT.95371865  DT.314812  DT.121318838  DT.100673206  DT.120007  DT.92457699 
    DT.121318831  DT.95215613  DT.95371856  DT.121318841  DT.121318801  DT.95371845  DT.92457712  DT.100033580 
    DT.121318813  DT.100858615  DT.100886554  DT.121318819  DT.91744068  DT.121318774  DT.100733496  DT.121318814 

    809 AceView cDNA sequences (see top 24):

    CD370599 F04863 AV709000 AI753952 AI356009 CD365703 AI221464 CB266012 
    AI767340 BE463641 BG169056 BX399392 AA917919 AA348116 BX399393 BU686522 
    BU789521 AA771741 AW072676 AY561849 AA788977 CA432942 AA593892 BX482027 
    CR606114 AW071679 AI682862 CA772061 AI025835 CB141496 BG109715 BC040653 
    BQ006028 AA992994 Z41475 BE222200 H48596 CA419391 CB159917 AL602712 
    AI094861 AI379418 AI521971 AI697388 AI459107 AA342406 AW189066 AA481559 
    BQ010045 N24741 AA227262 AA825745 CD614473 T40586 AA127074 BE819564 
    AL549180 AA350363 CD678610 AI911152 AW874643 AW513834 BQ721319 CA314017 
    AI422766 CB857888 BU674076 AI282785 BM667236 BM784356 Z39048 CA443712 
    AA359609 AA707470 AW578349 BE894736 CR607757 BE327660 BU689910 AW058394 
    CB157104 BX471492 AI826194 AW027976 BU633811 BM981955 AI954107 BQ576115 
    T69951 BU156133 AI092262 AA148755 CR616621 CB121644 AA909130 AI277990 
    AA448882 BU181960 AA358755 AA938644 AL708507 BM966891 AW237255 BX280335 
    BQ017830 BM857490 AA598735 Z45838 BU742669 BM967103 BF933211 BM972440 
    T83661 AW292432 AI372901 AI868727 AI361127 CB051868 BM975466 AA280873 
    CN479036 BM676071 BQ613776 T29503 BI669980 BQ067732 AA481012 AU136365 
    AW130220 AI423220 AA825760 AI969208 BI837756 AW951386 BG035632 AA360621 
    AI368840 BG430862 N51098 CD298869 AI097661 BE045656 BI910670 BI551966 
    CD653927 BI599743 AL598543 NM_013995 BX441182 CF128705 BE348530 CA445607 
    BE880985 BE968681 BU183786 T27031 CB956626 CF618745 AW664395 BQ425930 
    AI700945 H77564 BM989205 AU131820 Z33445 BE858845 AW503456 CA777013 
    AI150000 AW606991 BM479043 AI092292 AI424472 AA304644 BV199703 CD643308 
    BU568304 AI810331 AI962107 BM893706 AA125797 BU430584 N94781 AA447948 
    CD657452 CB140827 CB854328 BE000919 AW070610 BF899767 BQ447081 BQ776350 
    AA774464 BQ003064 BM055241 BG572314 AA490196 AI609407 AI580088 BE270547 
    AI269182 AW513594 AU138609 AA706741 CD655142 AI623255 CD652478 AW069281 
    CB143470 BU160345 AV694063 BF984425 BM845988 F08654 BQ006455 AI269232 
    CF272351 BM761145 AV708021 AA232472 BX118727 N31640 BM993158 BX648255 
    CB052410 BE326751 CD694708 AA306456 AI685331 AA481625 AL521377 CB111949 
    Z42930 BE241968 BP336490 AU135856 AI923808 D63026 AW016087 AU118588 
    AI624013 BE672563 AA662780 BQ018918 AU117130 AV731086 AI692532 AU156678 
    BV179119 BG249656 BU177907 X77196 BF670271 BP873572 BF793957 BM786781 
    AU157853 CB158859 BM544064 BI668993 AW675331 BE218712 AI168514 CB163640 
    BF573487 AW518997 AI031937 BP871688 AU136875 AW292574 BI551439 BI711868 
    AW873089 AW470703 F01897 T27128 BQ017100 D62941 BM966971 AI826694 
    BM728751 AA668893 BM450148 BG534388 BI549834 BI669660 CA777305 AI301997 
    CF541058 AI492294 BX435019 CB958146 BF939655 AW275139 BX379302 BG436364 
    BI492346 BV207928 BI092673 BE394155 AA904328 BI457964 AK126232 AA569528 
    BU929556 CD654035 BE327962 BF344345 BG771029 AA609629 N42209 AI074125 
    BQ417289 BG385638 BF373612 AL521378 AA280952 BI838068 BE501916 AA314150 
    AU139006 W56237 BE046130 CA448219 CA435621 BG428181 AA418142 BP872288 
    AI479585 U36336 AW890336 AV730441 BI600216 AW016891 AI223315 BM829285 
    BI552296 BF674583 CD104697 CB989444 BX113463 AW661994 AI094571 BG699100 
    BG702492 BC002965 BF438547 AI052288 BF666322 AU137186 AI799565 CA942791 
    BV178531 BE857608 AW837054 S79873 AA759108 BM455036 BM817970 BI548549 
    CB217113 AI087121 N62847 AI680787 C00545 BQ212569 CB118186 BU955321 
    BG546126 CD244950 AI917044 BM557613 BM747152 AU122484 H63796 NM_002294 
    CB051867 AA384987 AW576569 AI004872 AI376766 BM718041 N57095 AA361062 
    BX414543 AW576464 BM712728 AA209339 BX494566 AA052944 BU789790 D29162 
    AI811159 BG821903 BQ025604 N63482 AA085744 BG675338 AW206034 BM857717 
    AA228427 BX500144 AA826406 BG149537 AW748402 BG400273 BE767186 BF087207 
    AW611496 BI603638 BE407230 AV722439 BQ308790 BI670241 AI951916 BG715800 
    H49813 AA227839 BG572959 BE301240 AW021738 AW302189 CD512269 AA977167 
    BE881570 BQ014053 BG702772 AI057297 H77563 BE819450 R62619 AW956516 
    AA568885 R40327 AU153491 AI128270 BE880692 AW505266 AA515021 AW837157 
    AI619539 BG699244 BF984057 BG163889 AA576273 R25050 BG714522 BG771520 
    BE857474 N28966 AW996802 R98092 AA227840 AI023453 BG165198 BF762673 
    BM479065 CD674780 AW838283 AI701681 AI761959 BF031958 AW780225 D79776 
    BF983921 AA455167 AW937832 BI549147 BG507060 BX471491 BI601620 R77797 
    T26401 AL598258 BI670055 AA306272 BE669880 BF126196 AW082690 AA948364 
    BF337637 CD614474 N94756 T27129 BI549272 BI548977 BI550952 CB851858 
    CD697263 CD299829 BU430032 AI972316 BQ631029 BX379301 CD698195 AI678281 
    BM904928 AW371637 BG705996 BM146801 CA407490 BP335272 BG506506 BM273000 
    Z36265 H83687 W86734 AA148995 J04183 AV652163 BQ778436 BF525434 
    BU428452 T83825 AV698379 AW243853 AA417965 AA456539 BE677198 BE819615 
    AI356787 AA357492 BQ309039 AW955301 N63463 BM805428 BX397089 CA772351 
    BF126534 BV167885 CF136348 BG699327 BI547744 BF222402 BG707913 AI432614 
    BF798819 BF357934 BG719002 N71940 BX484340 BX378131 BQ287825 BF957400 
    BE897635 BG427658 W93718 AA657830 N55022 W32077 BE891758 BF572689 
    BF339611 AI275637 T69903 N53504 BX642714 N77211 CD692514 AA883527 
    BF214505 R63057 C04197 CD299153 AV692211 AA206048 H29263 H23858 
    CD684217 AA577284 BF691610 AV723706 H83707 BE561678 H48790 AI095427 
    BF916974 AW602947 BI711579 BX436451 AV761223 H09881 BG697113 R68253 
    AA303924 T39434 BI198212 AA576265 BU198192 BF673659 AV689911 AI366380 
    AI674804 AW068907 BI551372 N77754 AA309855 BI907407 AI423449 AW968679 
    AV662051 N45601 CD698262 AA053501 CF137544 AW340744 H29346 AI366364 
    BG623826 AI241534 BE177530 BQ308038 BF330260 BF761907 T63671 BI763906 
    BE897971 N94804 AA244335 BP336447 BF213237 BU157079 CD683576 CD705657 
    AV688071 C21402 N80157 BF086427 CD104948 BE819581 AI797624 AU144045 
    T32396 BI596979 BE540412 BG951841 CB050882 BF701680 W19660 AI800108 
    BG399502 AA814831 BF819195 AI973078 AW276273 BF924944 R65868 BE879380 
    AA207254 N99676 AA148616 AW304751 AV754219 T10914 AA658393 BQ301664 
    AI468173 BE769379 R33992 AW089111 BG164302 BM698076 R65700 R78159 
    AA404511 AV732551 BE078205 AU145109 CB989197 AL573484 AV709552 AW242869 
    R67188 BE925714 BF826927 AA854447 CA943033 N58035 AI582014 AA854549 
    BF357915 AI366553 AA706295 CD366465 AW797236 BX414544 H09796 AW955413 
    CK824132 AA609975 BF247226 BF761764 AW750318 BU160565 BF131759 H22728 
    H24010 W93719 BF030725 AI038047 BF956341 T70913 BE769391 BE185720 
    BE931698 BF978499 BF089672 R60000 AI146872 BF130701 BE245194 BI669033 
    W31585 AV753771 BF330258 BE894975 BE000942 AA043891 AA948353 BE833443 
    H83328 AI557396 BQ222525 R45389 AU099706 BF171533 BE708018 AA337053 
    R98093 AV749031 CD697461 BF248057 AA244384 BG003439 BE172543 AW997114 
    BI033816 BF030009 W03685 AA922026 BF893157 W21947 BG698385 BE831550 
    BG771468 BF090131 R97806 R97855 R26568 H49558 BG035554 AI476497 
    CF144791 AW518570 BG168312 BE926076 AI285170 BU198161 BE620089 BF589566 
    D58313 R23654 H63755 BE710300 BG571370 BF743910 BG702350 N72160 
    R14336 BE242698 BE005683 AW388905 BE934775 R31719 BQ360548 BF207646 
    BE830680 R62670 BF743914 BQ888267 BE813928 BF094044 BE245222 AA092234 
    R31677 R13247 AV662088 R40662 R68547 AW806190 AA361826 BF826931 
    BF089416 AW602919 BU166099 BE694908 BG167002 AW466376 AW580056 AA148996 
    AI266417 BE768545 AV728401 BG290877 R00849 BG956711 N63506 BE967372 
    AW578968 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for LAMP2 (see all 13)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c · 6d ^ 7a · 7b · 7c · 7d · 7e ^ 8a · 8b ^ 9 ^ 10a ·
    SP1:                                                                          -                                                                                 
    SP2:                                                                          -                                                                                 
    SP3:                                                                                                                                                            
    SP4:                                                              -     -     -     -     -     -     -     -     -     -     -     -     -                     
    SP5:                                                  -     -     -     -     -     -     -     -     -     -     -                                             

    ExUns: 10b ^ 11a · 11b ^ 12a · 12b · 12c ^ 13
    SP1:        -     -                           
    SP2:        -     -     -     -     -         
    SP3:                                          
    SP4:                                          
    SP5:                                          


    ECgene alternative splicing isoforms for LAMP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    LAMP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCATTATAA
    LAMP2 Expression
    About this image


    LAMP2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 19) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
     
     Ovary (Reproductive System)
             Oviduct
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    LAMP2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    LAMP2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.496684

    UniProtKB/Swiss-Prot: LAMP2_HUMAN, P13473
    Tissue specificity: Isoform LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas,
    low in brain and skeletal muscle. Isoform LAMP-2B is highly expressed in skeletal muscle, less in brain,
    placenta, lung, kidney and pancreas, very low in liver

        Custom PCR Arrays for LAMP2
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for LAMP2
    OriGene qSTAR qPCR primer pairs in human, mouse for LAMP2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat LAMP2
    QuantiTect SYBR Green Assays in human, mouse, rat LAMP2
    QuantiFast Probe-based Assays in human, mouse, rat LAMP2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LAMP2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for LAMP2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Lamp21 , 5 lysosomal-associated membrane protein 21, 5 74.46(n)1
    61.94(a)1
      X (22.67 cM)5
    167841  NM_010685.31  NP_034815.21 
     384013575 
    chicken
    (Gallus gallus)
    Aves LAMP21 lysosomal-associated membrane protein 2 58.81(n)
    49.12(a)
      414800  NM_001001749.1  NP_001001749.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.308952 Xenopus laevis transcribed sequence with weak similarity more 76.92(n)    CA985629.1 
    zebrafish
    (Danio rerio)
    Actinopterygii lamp26
    lysosomal membrane glycoprotein 2
    32(a)
    1 ↔ 1
    14(34448790-34456576) ENSDARG00000014914
    fruit fly
    (Drosophila melanogaster)
    Insecta Lamp16
    Lamp1
    21(a)
    1 → many
    2L(21573389-21577103)


    ENSEMBL Gene Tree for LAMP2 (if available)
    TreeFam Gene Tree for LAMP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for LAMP2 gene
    LAMP12  LAMP32  CD682  
    1 SIMAP similar gene for LAMP2 using alignment to 4 protein entries:     LAMP2_HUMAN (see all proteins):
    LAMP1

    LAMP2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for LAMP2 (see all 626)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0262304
    Danon disease (DAND)4--see VAR_0262302 W R mis40--------
    rs1048948591,2
    Cpathogenic1119569602(-) GCTACC/TGGGAT 6 R W mis10--------
    rs1048948581,2
    Cpathogenic1119570339(-) GCTCCA/GGTAAG 6 I V mis10--------
    rs1048948571,2
    Cpathogenic1119576746(-) TTGTAC/TAAGCT 6 Q * stg10--------
    rs128344701,2
    C,F,A--119553449(+) AAATTG/AAGCAT 2 -- ds50015Minor allele frequency- A:0.25NA WA CSA 8
    rs128403861,2
    C,F,A--119553475(+) GGAATG/TTAAAG 2 -- ds50013Minor allele frequency- T:0.40NA CSA 5
    rs1508259061,2
    C--119553599(+) ATACGC/TGGAAA 2 -- ds50010--------
    rs1904559521,2
    C--119553816(+) ATTCAA/CGAAAC 2 -- ds50010--------
    rs1132850131,2
    C,F--119554017(+) ATACAT/ACCAAA 2 -- ut311Minor allele frequency- A:0.50WA 2
    rs27481,2
    C,F,O,A,H--119554027(+) AACTTT/CAGTTA 2 -- ut3117Minor allele frequency- C:0.29MN NS EA NA 2353

    HapMap Linkage Disequilibrium report for LAMP2 (119560003 - 119603220 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for LAMP2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2659227CNV Deletion23128226
    esv2740433CNV Deletion23290073
    nsv528786CNV Gain19592680
    dgv2470e1CNV Complex17122850

    Human Gene Mutation Database (HGMD): LAMP2
    Locus Specific Mutation Databases (LSDB): LAMP2

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing LAMP2
    DNA2.0 Custom Variant and Variant Library Synthesis for LAMP2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 309060   
    OMIM disorders: 300257  
    UniProtKB/Swiss-Prot: LAMP2_HUMAN, P13473
  • Danon disease (DAND) [MIM:300257]: DAND is a lysosomal glycogen storage disease characterized by the
    clinical triad of cardiomyopathy, vacuolar myopathy and mental retardation. It is often associated with an
    accumulation of glycogen in muscle and lysosomes. Note=The disease is caused by mutations affecting the gene
    represented in this entry

  • Selected diseases for LAMP2 (see all 43):    
    About MalaCards
    danon disease    vacuolar myopathy    salla disease    hermansky-pudlak syndrome
    chediak-higashi syndrome    cystinosis    glycogen storage disease    protein s deficiency
    gaucher's disease    pilocytic astrocytoma    zellweger syndrome    lysosomal storage disease
    dilated cardiomyopathy    hypertrophic cardiomyopathy    hematopoietic stem cell transplantation    tremor
    myopathy    myeloproliferative disorder    hemangioma    vasculitis

    5 diseases from the University of Copenhagen DISEASES database for LAMP2:
    Danon disease     Hypertrophic cardiomyopathy     Myopathy     Glycogen storage disease
    Intellectual disability

    LAMP2 for disorders           About GeneDecksing

    Selected Novoseek inferred disease relationships for LAMP2 gene (see all 16)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    danon disease 98.6 49 18282207 (4), 11427988 (3), 20173215 (3), 18004770 (2) (see all 30)
    myopathy 76.1 17 16565504 (2), 15907287 (2), 18376150 (1), 15889279 (1) (see all 11)
    lysosomal acid phosphatase 73.5 2 9746610 (1), 8370478 (1)
    pompe disease 69.7 1 15673802 (1)
    glycogen storage disease 68.4 3 11552028 (1), 18691923 (1), 16973206 (1)
    cardiomyopathy 62.9 11 19318653 (4), 18376150 (1), 15907287 (1), 15889279 (1) (see all 8)
    hermansky-pudlak syndrome 62.6 1 8743190 (1)
    mental retardation 53 4 16565504 (1), 18004770 (1), 15907287 (1), 16217705 (1)
    protein deficiency 51.3 8 16565504 (3), 18393115 (1), 15907287 (1)
    dilated cardiomyopathy 43 1 17541230 (1)

    Genetic Association Database (GAD): LAMP2
    Human Genome Epidemiology (HuGE) Navigator: LAMP2 (5 documents)

    Export disorders for LAMP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for LAMP2 gene, integrated from 10 sources (see all 206):
    (articles sorted by number of sources associating them with LAMP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Glycogen storage diseases presenting as hypertrophic cardiomyopathy. (PubMed id 15673802)1, 2, 9 Arad M....Seidman J.G. (N. Engl. J. Med. 2005)
    2. Asymptomatic hyperCKemia in a case of Danon disease due to a missense mutation in Lamp-2 gene. (PubMed id 15907287)1, 2, 9 Musumeci O.... Toscano A. (Neuromuscul. Disord. 2005)
    3. The polylactosaminoglycans of human lysosomal membrane glycoproteins lamp-1 and lamp-2. Localization on the peptide backbones. (PubMed id 2243102)1, 2, 9 Carlsson S.R. and Fukuda M. (J. Biol. Chem. 1990)
    4. Unifying nomenclature for the isoforms of the lysosomal membrane protein LAMP-2. (PubMed id 16190986)1, 2, 9 Eskelinen E.L....Saftig P. (Traffic 2005)
    5. Shared genetic causes of cardiac hypertrophy in children and adults. (PubMed id 18403758)1, 4, 9 Morita H.... Seidman C.E. (N. Engl. J. Med. 2008)
    6. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    7. Integral and associated lysosomal membrane proteins. (PubMed id 17897319)1, 2 Schroeder B.... Hasilik A. (Traffic 2007)
    8. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    9. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (J. Proteome Res. 2005)
    10. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (Protein Sci. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 3920 HGNC: 6501 AceView: LAMP2 Ensembl:ENSG00000005893 euGenes: HUgn3920
    ECgene: LAMP2 Kegg: 3920 H-InvDB: LAMP2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for LAMP2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for LAMP2 Genetics and Cytogenetics in Oncology and Haematology
    GeneReviewshttp://www.ncbi.nlm.nih.gov/books/NBK1116/?term=LAMP2[genesymbol]

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for LAMP2 gene:
    Search GeneIP for patents involving LAMP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Antibodies for LAMP2 (LAMP2/CD107b)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Recombinant/Natural Proteins for LAMP2 (LAMP2/CD107b)   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for LAMP2   OriGene RNAi products in human, mouse, rat for LAMP2  
     OriGene qPCR primer pairs and template standards for LAMP2   OriGene Protein Over-expression Lysate for LAMP2  
     OriGene MassSpec something-or-other for LAMP2   OriGene clones in human, mouse for LAMP2  
     OriGene qSTAR qPCR primer pairs in human, mouse for LAMP2   OriGene Purified Protein for LAMP2  
     OriGene ORF clones in mouse, rat for LAMP2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for LAMP2   OriGene Custom Protein Services for LAMP2  

     
     
     Block miRNA regulation of human, mouse, rat LAMP2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing LAMP2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat LAMP2 Predesigned siRNA for gene silencing in human, mouse, rat LAMP2
     QuantiFast Probe-based Assays in human, mouse, rat LAMP2 QuantiTect SYBR Green Assays in human, mouse, rat LAMP2
     Custom PCR Arrays for LAMP2 Search Chromatin IP Primers for LAMP2
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat LAMP2  GeneGlobe Interaction Network for LAMP2
     Regulatory tfbs in LAMP2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for LAMP2 GenScript cDNA clones with any tag delivered in your preferred vector for LAMP2
     GenScript Custom Assay Services for LAMP2 GenScript Custom overexpressing Cell Line Services for LAMP2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for LAMP2
     Proteins for LAMP2
     Cell Lysates for LAMP2
     cDNA Clones for LAMP2
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     LAMP2 antibodies
     LAMP2 proteins
     LAMP2 lysates
     Antibodies for LAMP2
     See all of Abcam's Antibodies, Kits and Proteins for LAMP2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for LAMP2
     Proteins for LAMP2
     Antibodies for LAMP2
     ELISAs for LAMP2
     CLIAs for LAMP2



     Browse ESI BIO Cell Lines and PureStem Progenitors for LAMP2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LAMP2
     SwitchGear 3'UTR luciferase reporter plasmids for LAMP2
     SwitchGear Promoter luciferase reporter plasmids for LAMP2
     ThermoFisher Antibody for LAMP2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LAMP2
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for LAMP2
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for LAMP2
     LSBio Antibodies in human, mouse, rat for LAMP2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      LAMP2 gene at Home site.
    Version: 3.12.166 28 Aug 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4