Aliases for LAMP2 Gene
External Ids for LAMP2 Gene
Previous GeneCards Identifiers for LAMP2 Gene
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008]
GeneCards Summary for LAMP2 Gene
LAMP2 (Lysosomal-Associated Membrane Protein 2) is a Protein Coding gene. Diseases associated with LAMP2 include danon disease and glycogen storage disease due to lamp-2 deficiency. Among its related pathways are Hemostasis and Response to elevated platelet cytosolic Ca2+. GO annotations related to this gene include enzyme binding and protein domain specific binding. An important paralog of this gene is LAMP3.
UniProtKB/Swiss-Prot for LAMP2 Gene
Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.