LAMP2 Gene
protein-coding GIFtS: 67
GCID: GC0XM119560
|
|
lysosomal-associated membrane protein 2
| |
Aliases
for LAMP2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Lysosomal-Associated Membrane Protein 21 2 | | LAMPB2 5 | | CD107b1 2 | | LGP1102 | | Lysosome-Associated Membrane Protein 22 3 | | Lysosome-Associated Membrane Glycoprotein 22 | | LAMP-22 3 | | CD107b Antigen3 | | CD107 Antigen-Like Family Member B2 3 | | |
Export aliases for LAMP2 gene to outside databasesPrevious GC identifers: GC0XM114382 GC0XM116550 GC0XM117540 GC0XM118318 GC0XM119346 GC0XM119448 GC0XM109011 |
Summaries
for LAMP2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for LAMP2:
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein providesselectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in theprotection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multipletranscript variants encoding distinct proteins. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: LAMP2_HUMAN, P13473Function: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion,maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane),and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens
Gene Wiki entry for LAMP2
|
Genomic Views
for LAMP2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_011786.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the LAMP2 gene promoter:
TBP RFX1 AP-2alpha isoform 3 Nkx2-2 NCX/Ncx AP-2alpha isoform 2 TFIID AP-2alpha isoform 4 AP-2alpha AP-2alphaA
Other transcription factors
Search SABiosciences Chromatin IP Primers for LAMP2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LAMP2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq24 Ensembl cytogenetic band: Xq24 HGNC cytogenetic band: Xq24-q25LAMP2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM119560: view genomic region
(about GC identifiers)
Start:
|
119,560,003 bp from pter |
End:
|
119,603,220 bp from pter |
Size:
|
43,218 bases |
Orientation:
|
minus strand |
|
Proteins
for LAMP2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: LAMP2_HUMAN, P13473 (See
protein sequence)Recommended Name: Lysosome-associated membrane glycoprotein 2 precursor Size: 410 amino acids; 44961 Da
Subcellular location: Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type Imembrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=This protein shuttles betweenlysosomes, endosomes, and the plasma membrane
Secondary accessions: A8K4X5 D3DTF0 Q16641 Q6Q3G8 Q96J30 Q99534 Q9UD93Alternative splicing: 3 isoforms: P13473-1 P13473-2 P13473-3 Explore the universe of human proteins at neXtProt for LAMP2: NX_P13473
Post-translational modifications:
O- and N-glycosylated; some of the 16 N-linked glycans are polylactosaminoglycans1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P13473
LAMP2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001116078.1 NP_002285.1 NP_054701.1
ENSEMBL proteins: ENSP00000408411 ENSP00000200639 ENSP00000431526 ENSP00000360386 ENSP00000440506 ENSP00000440479 Reactome Protein details: P13473
Human Recombinant Protein Products:
Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10): About this table
LAMP2 for ontologies About GeneDecksing
LAMP2 Antibody Products:
Assay Products for LAMP2: |
Protein
Domains /
Families
for LAMP2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
LAMP2 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P13473ProtoNet protein and cluster: P13473 1 Blocks protein family: IPB002000 Lysosome-associated membrane glycoprotein (Lamp)/CD68
UniProtKB/Swiss-Prot: LAMP2_HUMAN, P13473Similarity: Belongs to the LAMP family |
Function
for LAMP2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: LAMP2_HUMAN, P13473Function: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion,maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane),and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens Genatlas biochemistry entry for LAMP2:lysosomal associated membrane protein 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LAMP2 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LAMP2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): LAMP2 (NM_013995) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for LAMP2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LAMP2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LAMP2 |
1 GenomeRNAi human phenotype for LAMP2:
Animal Models:
Mouse knock-out Lamp2tm1Psa for LAMP2
13 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Lamp2):
LAMP2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for LAMP2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Platelet degranulation | | | 2 | Platelet activation, signaling and aggregation | | | 3 | Senescence and Autophagy | | | 4 | Tuberculosis | | | 5 | Phagosome | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for LAMP2
4 
Reactome Pathways for LAMP2
3 
Kegg Pathways (Kegg details for LAMP2):
LAMP2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for LAMP2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 16)
5/25 Interacting proteins for LAMP2 (P134732, 3 ENSP000004084114) via UniProtKB, MINT, STRING, and/or I2D (see all 25)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
LAMP2 for ontologies About GeneDecksing
|
Drugs & Compounds
for LAMP2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
LAMP2 for compounds About GeneDecksing
 Browse Tocris compounds for LAMP2
6 Novoseek chemical compound relationships for LAMP2 gene About this table
Search CenterWatch for drugs/clinical trials and news about LAMP2
|
Transcripts
for LAMP2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for LAMP2 gene (3 alternative transcripts): NM_001122606.1 NM_002294.2 NM_013995.2 Unigene Cluster for LAMP2: Lysosomal-associated membrane protein 2 Hs.496684 [show with all ESTs]Unigene Representative Sequence: NM_0022946 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000434600(uc004est.4 uc004ess.4 uc011mtz.2) ENST00000200639
ENST00000486593 ENST00000371335(uc011mua.1 uc010nqp.1) ENST00000538785
ENST00000540603
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LAMP2 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LAMP2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): LAMP2 (NM_013995) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for LAMP2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LAMP2 |
Additional cDNA sequence: AK126232.1 AK291090.1 AK293931.1 AK295038.1 AK304405.1 AY561849.1 BC002965.1 BC040653.2 BX648255.1 J04183.1 S79873.1 U36336.1 X77196.1 24/51 DOTS entries (see all 51): DT.92457710 DT.95371837 DT.95371865 DT.314812 DT.121318838 DT.100673206 DT.120007 DT.92457699 DT.121318831 DT.95215613 DT.95371856 DT.121318841 DT.121318801 DT.95371845 DT.92457712 DT.100033580 DT.121318813 DT.100858615 DT.100886554 DT.121318819 DT.91744068 DT.121318774 DT.100733496 DT.121318814 24/809 AceView cDNA sequences (see all 809): AI954107 AI911152 H48596 AA917919 AW027976 AI092262 BM667236 BM966891 AA358755 AL602712 BM972440 BQ721319 CD370599 AA707470 BG169056 BQ017830 BQ576115 CR606114 BF933211 T40586 AA448882 AY561849 AA788977 BX482027
GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for LAMP2 (see all 13) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | |
| ExUns: | 10b | ^ | 11a | · | 11b | ^ | 12a | · | 12b | · | 12c | ^ | 13 |
|---|
|
| SP1: | | | - | | - | | | | | | | | | | |
| SP2: | | | - | | - | | - | | - | | - | | | | |
| SP3: | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for LAMP2
|
Expression
for LAMP2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| LAMP2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCCATTATAA
About this image
See LAMP2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for LAMP2
SOURCE GeneReport for Unigene cluster: Hs.496684
UniProtKB/Swiss-Prot: LAMP2_HUMAN, P13473Tissue specificity: Isoform LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas, lowin brain and skeletal muscle. Isoform LAMP-2B is highly expressed in skeletal muscle, less in brain, placenta, lung,kidney and pancreas, very low in liver
SABiosciences Custom PCR Arrays for LAMP2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LAMP2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat LAMP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LAMP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LAMP2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LAMP2 |
Orthologs
for LAMP2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for LAMP2 gene from 4/17 species (see all 17) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
LAMP21 |
lysosomal-associated membrane protein 2 |
62.81(n)
55.03(a) |
|
414800 NM_001001749.1 NP_001001749.1 |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.308952 |
Xenopus laevis transcribed sequence with weak similarity more |
76.92(n) |
|
CA985629.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
lamp26 |
lysosomal membrane glycoprotein 2 |
29(a) |
1 ↔ 1 |
14(34448790-34456576) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Lamp16 |
Lamp1 |
18(a) |
1 → many |
2L(21573389-21577103) |
ENSEMBL Gene Tree for LAMP2 (if available)
TreeFam Gene Tree for LAMP2 (if available) |
Paralogs
for LAMP2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for LAMP2 gene
- LAMP12 LAMP32 CD682
1 SIMAP similar gene for LAMP2 using alignment to 4 protein entries: LAMP2_HUMAN (see all proteins):LAMP1
LAMP2 for paralogs About GeneDecksing
|
Genomic Variants
for LAMP2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for LAMP2 (119560003 - 119603220 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for LAMP2
1 CNV: 4168
Human Gene Mutation Database (HGMD): LAMP2
Locus Specific Mutation Databases (LSDB): LAMP2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LAMP2 |
|
Disorders
/ Diseases
for LAMP2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
LAMP2 for disorders About GeneDecksing
OMIM gene information: 309060
OMIM disorders: 300257
UniProtKB/Swiss-Prot: LAMP2_HUMAN, P13473
Defects in LAMP2 are the cause of Danon disease (DAND) [MIM:300257]; also known as glycogen storage diseasetype 2B (GSD2B). DAND is a lysosomal glycogen storage disease characterized by the clinical triad of cardiomyopathy,vacuolar myopathy and mental retardation. It is often associated with an accumulation of glycogen in muscle andlysosomes
20/44  diseases for LAMP2 (see all 44): About MalaCardshermansky-pudlak syndrome glycogen storage disease iib glycogen storage disease chediak-higashi syndrome
danon disease vacuolar myopathy lysosomal storage disease salla disease
dilated cardiomyopathy pilocytic astrocytoma systemic lupus erythematosus intellectual disability
lupus erythematosus hypertrophic cardiomyopathy zellweger syndrome cardiomyopathy
cystinosis protein s deficiency myeloproliferative disorder gaucher's disease
5 diseases from the University of Copenhagen DISEASES database for LAMP2:Lysosomal storage disease Hypertrophic cardiomyopathy Glycogen storage disease Myopathy
Intellectual disability 10/16 Novoseek disease relationships for LAMP2 gene (see all 16) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| danon disease |
98.6 |
49 |
18282207 (4), 11427988 (3), 20173215 (3), 18004770 (2), 16217705 (2), 15907287 (2), 19057086 (2), 18990578 (2), 11552028 (1), 15253947 (1), 16565504 (1), 14561493 (1), 15889279 (1), 16973206 (1), 16144992 (1), 14598234 (1), 12847175 (1), 20120346 (1), 17873513 (1), 15673802 (1), 10972293 (1), 12507414 (1), 19318653 (1), 20513107 (1), 17541230 (1), 18393115 (1), 17821837 (1), 18377432 (1), 17296900 (1), 18376150 (1) (see top 4) |
| myopathy |
76.1 |
17 |
16565504 (2), 15907287 (2), 18376150 (1), 15889279 (1), 11427988 (1), 18282207 (1), 19057086 (1), 16217705 (1), 17541230 (1), 18004770 (1), 18393115 (1) (see top 4) |
| lysosomal acid phosphatase |
73.5 |
2 |
9746610 (1), 8370478 (1) |
| pompe disease |
69.7 |
1 |
15673802 (1) |
| glycogen storage disease |
68.4 |
3 |
11552028 (1), 18691923 (1), 16973206 (1) |
| cardiomyopathy |
62.9 |
11 |
19318653 (4), 18376150 (1), 15907287 (1), 15889279 (1), 16217705 (1), 18282207 (1), 15673802 (1), 18691923 (1) (see top 4) |
| hermansky-pudlak syndrome |
62.6 |
1 |
8743190 (1) |
| mental retardation |
53 |
4 |
16565504 (1), 18004770 (1), 15907287 (1), 16217705 (1) |
| protein deficiency |
51.3 |
8 |
16565504 (3), 18393115 (1), 15907287 (1) |
| dilated cardiomyopathy |
43 |
1 |
17541230 (1) |
Human Genome Epidemiology (HuGE) Navigator: LAMP2 (5 documents)
Export disorders for LAMP2 gene to outside databases
|
Publications
for LAMP2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for LAMP2 gene, integrated from 9 sources (see all 192):
(articles sorted by number of sources associating them with LAMP2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Glycogen storage diseases presenting as hypertrophic cardiomyopathy. (PubMed id 15673802)1, 2, 9 Arad M....Seidman J.G. (2005)
- Asymptomatic hyperCKemia in a case of Danon disease due to a missense mutation in Lamp-2 gene. (PubMed id 15907287)1, 2, 9 Musumeci O.... Toscano A. (2005)
- The polylactosaminoglycans of human lysosomal membrane glycoproteins lamp-1 and lamp-2. Localization on the peptide backbones. (PubMed id 2243102)1, 2, 9 Carlsson S.R. and Fukuda M. (1990)
- Unifying nomenclature for the isoforms of the lysosomal membrane protein LAMP-2. (PubMed id 16190986)1, 2, 9 Eskelinen E.L....Saftig P. (2005)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)
- Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. (PubMed id 12754519)1, 2 Zhang H.... Aebersold R. (2003)
- An alternatively spliced form of the human lysosome-associated membrane protein-2 gene is expressed in a tissue-specific manner. (PubMed id 7488019)1, 2 Konecki D.S....Lichter-Konecki U. (1995)
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External Searches for LAMP2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing LAMP2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing LAMP2 gene
(According to HUGE)
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Specialized Databases showing LAMP2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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About This Section
| Patent Information for LAMP2 gene:
Search GeneIP for patents involving LAMP2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for LAMP2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | OriGene Antibodies for LAMP2 | | OriGene shRNA RFP for LAMP2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for LAMP2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LAMP2 | | | OriGene Protein Over-expression Lysate for LAMP2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for LAMP2 | | OriGene 3'-UTR Clone for LAMP2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LAMP2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LAMP2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for LAMP2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for LAMP2 | | OriGene Custom Protein Services for LAMP2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat LAMP2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LAMP2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LAMP2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LAMP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LAMP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LAMP2 |
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| | | | Search Tocris compounds for LAMP2 |
| |  |  |  |  | | | | | | Recombinant Protein for LAMP2 |
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 | | | LAMP2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LAMP2 |
|  |  |  | | | | ThermoFisher Antibody for LAMP2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LAMP2 |
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