Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
- GeneCards Team
- Our Publications
- Citing GeneCards
- Licensing Agreement
- Weizmann Institute
- LifeMap Sciences Inc
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

LAMA3 Gene

protein-coding GIFtS: 65
GCID: GC18P021269

Laminin, Alpha 3

(Previous names: laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM60...)
(Previous symbol: LAMNA)

38 related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Laminin, Alpha 3¹ ²		E170² ³
LAMNA¹ ² ³		LOCS² ⁵
Laminin, Alpha 3 (Nicein (150kD), Kalinin (165kD), BM600 (150kD), Epilegrin)¹ ²		BM600²
Epiligrin 170 KDa Subunit² ³		BM600 150kD Subunit²
Epiligrin Subunit Alpha² ³		Epiligrin Alpha 3 Subunit²
Kalinin Subunit Alpha² ³		Kalinin 165kD Subunit²
Laminin-5 Subunit Alpha² ³		lama3a²
Laminin-6 Subunit Alpha² ³		Laminin Subunit Alpha-3²
Laminin-7 Subunit Alpha² ³		Laminin-5 Alpha 3 Chain²
Nicein Subunit Alpha² ³		Nicein 150kD Subunit²

External Ids:	HGNC: 6483¹	Entrez Gene: 3909²	Ensembl: ENSG00000053747⁷	OMIM: 600805⁵	UniProtKB: Q16787³

Export aliases for LAMA3 gene to outside databases

Previous GC identifers: GC18P021345 GC18P021184 GC18P019521 GC18P019523 GC18P018125

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for LAMA3 Gene:

Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into

tissues during embryonic development by interacting with other extracellular matrix components. The protein encoded by

this gene is the alpha-3 subunit of laminin 5, which is a complex glycoprotein composed of three subunits (alpha,

beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of

keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis

bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

(provided by RefSeq, Jul 2008)

GeneCards Summary for LAMA3 Gene:

LAMA3 (laminin, alpha 3) is a protein-coding gene. Diseases associated with LAMA3 include laryngoonychocutaneous syndrome, and lama3-related junctional epidermolysis bullosa, and among its related super-pathways are ECM-receptor interaction and Focal Adhesion. GO annotations related to this gene include structural molecule activity and receptor binding. An important paralog of this gene is LAMA5.

UniProtKB/Swiss-Prot: LAMA3_HUMAN, Q16787

Function: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and

organization of cells into tissues during embryonic development by interacting with other extracellular matrix

components

Function: Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and

integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80,

(3) differentiation of keratinocytes

Gene Wiki entry for LAMA3 (Laminin, alpha 3) Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000018.9 NC_018929.2 NT_010966.14

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the LAMA3 gene promoter:
E2F-3a E2F-4 E2F-5 Olf-1 E2F-2 E4BP4 PPAR-alpha E2F-1 E2F c-Myb
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): LAMA3 promoter sequence

Search SABiosciences Chromatin IP Primers for LAMA3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LAMA3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q11.2 Ensembl cytogenetic band: 18q11.2 HGNC cytogenetic band: 18q11.2

LAMA3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LAMA3 gene location

GeneLoc information about chromosome 18 GeneLoc Exon Structure

GeneLoc location for GC18P021269: view genomic region (about GC identifiers)

Start:	21,269,407 bp from pter	End:	21,535,030 bp from pter
Size:	265,624 bases	Orientation:	plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: LAMA3_HUMAN, Q16787 (See protein sequence)

Recommended Name: Laminin subunit alpha-3 precursor

Size: 3333 amino acids; 366649 Da

Subunit: Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma),

which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms

with globules at each end. Alpha-3 is a subunit of laminin-5 (laminin-332 or epiligrin/kalinin/nicein), laminin-6

(laminin-311 or K-laminin) and laminin-7 (laminin-321 or KS-laminin)

Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component

Secondary accessions: Q13679 Q13680 Q6VU67 Q6VU68 Q6VU69 Q76E14 Q96TG0

Alternative splicing: 4 isoforms: Q16787-2 Q16787-1 Q16787-3 Q16787-4

Explore the universe of human proteins at neXtProt for LAMA3: NX_Q16787

Explore proteomics data for LAMA3 at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q16787

LAMA3 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins (4 alternative transcripts):

NP_000218.2 NP_001121189.1 NP_001121190.1 NP_937762.1

ENSEMBL proteins:

ENSP00000324532 ENSP00000468316 ENSP00000382432 ENSP00000467662 ENSP00000269217

ENSP00000466557 ENSP00000464836 ENSP00000467473 ENSP00000466658 ENSP00000468315

Reactome Protein details: Q16787
Human Recombinant Protein Products for LAMA3:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate for LAMA3 OriGene Custom MassSpec OriGene Custom Protein Services for LAMA3
	GenScript Custom Purified and Recombinant Proteins Services for LAMA3
	Novus Biologicals LAMA3 Protein Novus Biologicals LAMA3 Lysate
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Cloud-Clone Corp.

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	TAS	--
GO:0005604	basement membrane	TAS	8586427
GO:0005606	laminin-1 complex	IEA	--
GO:0005610	laminin-5 complex	IEA	--

LAMA3 for ontologies About GeneDecksing

LAMA3 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	R&D Systems Antibodies for LAMA3 (Laminin alpha 3/Laminin-5)
	Browse OriGene Antibodies OriGene Custom Antibody Services for LAMA3
	GenScript Custom Superior Antibodies Services for LAMA3
	Novus Biologicals LAMA3 Antibodies
	Abcam antibodies for LAMA3
	Browse Antibodies at Cloud-Clone Corp.
	Search ThermoFisher Antibodies for LAMA3
	LSBio Antibodies in human, mouse, rat for LAMA3

Assay Products for LAMA3:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for LAMA3
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for LAMA3
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs at Cloud-Clone Corp. Browse CLIAs at Cloud-Clone Corp.

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HGNC Gene Families:

LAM: Laminins

5/11 InterPro protein domains (see all 11):

IPR018031 Laminin_B_subgr

IPR000034 Laminin_B_type_IV

IPR008211 Laminin_N

IPR013320 ConA-like_subgrp

IPR009030 Growth_fac_rcpt_N_dom

Graphical View of Domain Structure for InterPro Entry Q16787

ProtoNet protein and cluster: Q16787

2 Blocks protein domains:

IPB001791 Laminin G

IPB009254 Laminin I

UniProtKB/Swiss-Prot: LAMA3_HUMAN, Q16787

Domain: The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil

structure

Domain: Domain G is globular

Similarity: Contains 15 laminin EGF-like domains

Similarity: Contains 5 laminin G-like domains

Similarity: Contains 1 laminin IV type A domain

Similarity: Contains 1 laminin N-terminal domain

LAMA3 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: LAMA3_HUMAN, Q16787

Function: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and

organization of cells into tissues during embryonic development by interacting with other extracellular matrix

components

Function: Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and

integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80,

(3) differentiation of keratinocytes

Induction: Laminin-5 is up-regulated in wound sites of human skin

Genatlas biochemistry entry for LAMA3:

laminin,alpha 3 polypeptide,heterotrimerizing with laminin beta 3 and gamma 2 in laminin 5 (kalinin/nicein),component

of cutaneous basement membrane zone

Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	sequence-specific DNA binding transcription factor activity	--	--
GO:0004871	signal transducer activity	--	--
GO:0005102	receptor binding	IEA	--
GO:0005198	structural molecule activity	NAS	8586427
GO:0005515	protein binding	--	--

LAMA3 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for LAMA3:

Decreased number of cells in m

5 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Lama3):

craniofacial

digestive/alimentary

growth/size

integument

mortality/aging

LAMA3 for phenotypes About GeneDecksing

Animal Models:
Mouse knock-out Lama3^tm1Crt for LAMA3

inGenious Targeting Laboratory - Custom generated mouse model solutions for LAMA3

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for LAMA3

miRNA Products:
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LAMA3
		8/23 QIAGEN miScript miRNA Assays for microRNAs that regulate LAMA3 (see all 23):
		hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-302e hsa-miR-520a-3p hsa-miR-372 hsa-miR-93

		SwitchGear 3'UTR luciferase reporter plasmid: LAMA3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for LAMA3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LAMA3
		Sirion Biotech Custom design and validation of potent shRNA sequences against LAMA3

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for LAMA3
			Sirion Biotech Customized adenovirus for potent knockdown of LAMA3

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene clones in human, mouse for LAMA3 (see all 17) OriGene ORF clones in mouse, rat for LAMA3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 4): LAMA3 (NM_000227)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for LAMA3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LAMA3

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for LAMA3
		Search LifeMap BioReagents cell lines for LAMA3
		Sirion Biotech Customized stable knockdown cell line services for LAMA3 Customized inducible knockdown cell line services for LAMA3

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LAMA3

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for LAMA3 About (see all 21)

See pathways by source

SuperPath

Contained pathways About

Non-integrin membrane-ECM interactions

	Non-integrin membrane-ECM interactions	0.44			ECM proteoglycans	0.38
	ECM-receptor interaction	0.42			Integrin cell surface interactions	0.32

Focal Adhesion

Focal Adhesion

0.64

Focal adhesion

0.64

Cell adhesion ECM remodeling

Cell adhesion ECM remodeling

0.31

Metalloproteases in connective tissue degradation

0.31

Integrin Pathway

Integrin Pathway	0.67	UPA-UPAR Pathway	0.56
FAK1 Signaling	0.67	Inhibition of Angiogenesis by TSP1	0.50
GnRH Signaling	0.56	Transendothelial Migration of Leukocytes	0.38

Rho Family GTPases

Rho Family GTPases	0.61	Molecular Mechanisms of Cancer	0.51
ERK Signaling	0.61	ILK Signaling	0.49
MAPK Signaling	0.58

Pathways by source See SuperPaths
Show all pathways

2 EMD Millipore Pathways for LAMA3

	Cell adhesion ECM remodeling
	Metalloproteases in connective tissue degradation

5/14 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for LAMA3 (see all 14)

	MAPK Signaling
	Molecular Mechanisms of Cancer
	PTEN Pathway
	CDK5 Pathway
	Transendothelial Migration of Leukocytes

1 GeneGo (Thomson Reuters) Pathway for LAMA3

Cell adhesion ECM remodeling

5 BioSystems Pathways for LAMA3

	Focal Adhesion
	Alpha6-Beta4 Integrin Signaling Pathway
	Syndecan-2-mediated signaling events
	Syndecan-4-mediated signaling events
	Validated transcriptional targets of AP1 family members Fra1 and Fra2

5/11 Reactome Pathways for LAMA3 (see all 11)

	Integrin cell surface interactions
	Assembly of collagen fibrils and other multimeric structures
	Collagen formation
	Anchoring fibril formation
	ECM proteoglycans

5/7 Kegg Pathways (Kegg details for LAMA3) (see all 7):

	PI3K-Akt signaling pathway
	Focal adhesion
	ECM-receptor interaction
	Toxoplasmosis
	Amoebiasis

LAMA3 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for LAMA3

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/42 Interacting proteins for LAMA3 (Q16787^{2, 3} ENSP00000324532⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 42)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SLC35E1	Q96K37²^,³, ENSP00000387152⁴	MINT-64295 I2D: score=3 STRING: ENSP00000387152
APC	P25054³, ENSP00000257430⁴	I2D: score=3 STRING: ENSP00000257430
LAMB3	Q13751³, ENSP00000348384⁴	I2D: score=2 STRING: ENSP00000348384
BMP1	P13497³, ENSP00000305714⁴	I2D: score=1 STRING: ENSP00000305714
LAMB1	P07942³, ENSP00000222399⁴	I2D: score=1 STRING: ENSP00000222399

About this table

Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006355	regulation of transcription, DNA-dependent	--	--
GO:0007155	cell adhesion	IEA	--
GO:0007165	signal transduction	--	--
GO:0008544	epidermis development	TAS	8586427
GO:0030155	regulation of cell adhesion	IEA	--

LAMA3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, IUPHAR, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

LAMA3 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for LAMA3

1 Novoseek inferred chemical compound relationship for LAMA3 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
kalinin	81.5	3	7573357 (1), 15953081 (1), 7635220 (1)

Search CenterWatch for drugs/clinical trials and news about LAMA3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for LAMA3 gene (4 alternative transcripts):

NM_000227.3 NM_001127717.1 NM_001127718.1 NM_198129.1

Unigene Cluster for LAMA3:

Laminin, alpha 3

Hs.436367 [show with all ESTs]

Unigene Representative Sequence: NM_198129

14 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000313654(uc002kuq.3) ENST00000585600 ENST00000399516(uc010dlv.2 uc002kur.3)

ENST00000591749 ENST00000592519 ENST00000269217(uc002kus.4 uc002kut.4)

ENST00000587184 ENST00000586751 ENST00000588770 ENST00000586709 ENST00000588164

ENST00000592442 ENST00000590104 ENST00000588004

miRNA Products:
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LAMA3
		8/23 QIAGEN miScript miRNA Assays for microRNAs that regulate LAMA3 (see all 23):
		hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-302e hsa-miR-520a-3p hsa-miR-372 hsa-miR-93

		SwitchGear 3'UTR luciferase reporter plasmid: LAMA3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for LAMA3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LAMA3
		Sirion Biotech Custom design and validation of potent shRNA sequences against LAMA3

Clone Products:		OriGene clones in human, mouse for LAMA3 (see all 17) OriGene ORF clones in mouse, rat for LAMA3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 4): LAMA3 (NM_000227)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for LAMA3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LAMA3

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for LAMA3
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat LAMA3
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LAMA3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LAMA3

Additional mRNA sequence:

AB208853.1 AK096422.1 AY327114.1 AY327115.1 AY327116.1 BC033663.1 BC043618.1 BC093406.1

L34155.1 L34156.1 X84392.1 X84900.1 X85107.1 X85108.1

9 DOTS entries:

DT.92448000 DT.95243961 DT.100754621 DT.92068550 DT.101971561 DT.99933393 DT.100016938 DT.95243939

DT.95243955

24/165 AceView cDNA sequences (see all 165):

BI335805 BP354564 BX101940 W67580 AU140779 CA392258 AY327114 BC043618

AI129128 BP353642 NM_198129 AY327116 NM_000227 CA446402 L34155 CA423430

AI567045 AK024889 AY327115 CA427431 AL708055 BX114291 CR621377 BG677741

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

LAMA3 expression in normal human tissues (normalized intensities) LAMA3 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: TGTATTTTAT

About this image

LAMA3 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database

5/4 selected tissues (see all 4) fully expand


Heart (Cardiovascular System)
Left Ventricle

Testis (Reproductive System)
Elongated Spermatid Seminiferous Tubules

Skeletal Muscle (Muscoskeletal System)
TONGUE

Lung (Respiratory System)

-- (Gastrointestinal Tract)
mouth

See LAMA3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for LAMA3

SOURCE GeneReport for Unigene cluster: Hs.436367

UniProtKB/Swiss-Prot: LAMA3_HUMAN, Q16787

Tissue specificity: Skin; respiratory, urinary, and digestive epithelia and in other specialized tissues with prominent

secretory or protective functions. Epithelial basement membrane, and epithelial cell tongue that migrates into a wound

bed. A differential and focal expression of the subunit alpha-3 is observed in the CNS

SABiosciences Expression via Pathway-Focused PCR Array including LAMA3:

Extracellular Matrix & Adhesion Molecules in human mouse rat

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for LAMA3
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat LAMA3
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LAMA3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LAMA3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LAMA3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for LAMA3 gene from 3/9 species (see all 9) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Lama3^{1 , 5}	laminin, alpha 3^{1, 5}	80.8(n)¹ 78.13(a)¹		18 (6.20 cM)⁵ 16774¹ NM_010680.1¹ NP_034810.1¹ 12334024⁵
chicken (Gallus gallus)	Aves	LAMA3¹	laminin, alpha 3	64.95(n) 58.71(a)		428524 XM_426078.3 XP_426078.3
lizard (Anolis carolinensis)	Reptilia	LAMA3⁶	laminin, alpha 3	55(a)	1 ↔ 1	4(37985524-38143246)

ENSEMBL Gene Tree for LAMA3 (if available)
TreeFam Gene Tree for LAMA3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for LAMA3 gene

LAMA5² LAMA2² MEGF9² LAMA1² LAMA4²

12 SIMAP similar genes for LAMA3 using alignment to 12 protein entries: LAMA3_HUMAN (see all proteins):

LamA3 LAMA5 MEGF9 HSPG2 LAMA2 LAMA4

LAMA1 ATRNL1 LAMC2 NTN1 LAMB2 LAMA4*-1

LAMA3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 18 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs112572800^1,2	C	--	18153164(+)	`GCTAAA/TTTTTT`	2	--	int¹		0	--	--	--	--
rs5823403^1,2	C,F	--	18268810(+)	`TTATT-/A/TAAA AAAAA`	2	--	int¹ trp³		3		NA CSA	6
rs112262111^1,2	F	--	18305618(+)	`ATGGCG/AAAACC`	2	--	int¹		1		CSA	2
rs113214620^1,2	C	--	18325122(+)	`GAAGGA/GAGGAA`	4	--	int¹		0	--	--	--	--
rs35301452^1,2	C	--	18347756(+)	`TTTTTT/-GAGAC`	4	--	int¹		1		NA	2
rs11448357^1,2	C	--	18351651(+)	`AAAAGA/-AAAAG`	4	--	int¹ trp³		1		NA	2
rs9952933^1,2	C	--	18351662(+)	`AAAAGA/GAAAAG`	4	--	int¹ trp³		0	--	--	--	--
rs34752262^1,2	C,F	--	18351663(+)	`AAAAGA/-AAAAG`	4	--	int¹		2		NA	4
rs143548754^1,2	C	--	18351663(+)	`AAAGA-/AAAAG AAAAG`	4	--	int¹		0	--	--	--	--
rs34277541^1,2	C	--	18352614(+)	`GGTAA-/TTTTTT`	4	--	int¹		1		NA	2

HapMap Linkage Disequilibrium report for LAMA3 (21269407 - 21519407 bp, first 250kb of LAMA3)

Structural Variations
Database of Genomic Variants (DGV) 8 variations for LAMA3: About this table

Variant ID	Type	Subtype	PubMed ID
esv2664111	CNV	Deletion	23128226
esv2556502	CNV	Deletion	19546169
esv2671824	CNV	Deletion	23128226
esv2716865	CNV	Deletion	23290073
esv2657446	CNV	Deletion	23128226
esv2839	CNV	Deletion	18987735
esv2716866	CNV	Deletion	23290073
nsv2228	CNV	Insertion	18451855

Human Gene Mutation Database (HGMD): LAMA3

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LAMA3

DNA2.0 Custom Variant and Variant Library Synthesis for LAMA3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

LAMA3 for disorders           About GeneDecksing

OMIM gene information: 600805
OMIM disorders: 226700  226650  245660
UniProtKB/Swiss-Prot: LAMA3_HUMAN, Q16787

Epidermolysis bullosa, junctional, Herlitz type (H-JEB) [MIM:226700]: An infantile and lethal form of

junctional epidermolysis bullosa, a group of blistering skin diseases characterized by tissue separation which occurs

within the dermo-epidermal basement In the Herlitz type, death occurs usually within the first six months of life.

Occasionally, children survive to teens. It is marked by bullous lesions at birth and extensive denudation of skin and

mucous membranes that may be hemorrhagic. Note=The disease is caused by mutations affecting the gene represented in

this entry

Laryngoonychocutaneous syndrome (LOCS) [MIM:245660]: Autosomal recessive epithelial disorder confined to the

Punjabi Muslim population. The condition is characterized by cutaneous erosions, nail dystrophy and exuberant vascular

granulation tissue in certain epithelia, especially conjunctiva and larynx. Note=The disease is caused by mutations

affecting the gene represented in this entry

20/38 diseases for LAMA3 (see all 38): About MalaCards

laryngoonychocutaneous syndrome lama3-related junctional epidermolysis bullosa junctional epidermolysis bullosa maternal uniparental disomy of chromosome 1

presbyopia epidermolysis bullosa acquisita epidermolysis bullosa cicatricial pemphigoid

senile cataract crescentic glomerulonephritis endocervicitis congenital muscular dystrophy

malignant peripheral nerve sheath tumor bullous pemphigoid skin disease toxoplasmosis

spinal cord injury myopia glomerulonephritis cataract

4 diseases from the University of Copenhagen DISEASES database for LAMA3:

Epidermolysis bullosa Senile cataract Myopia Glaucoma

10/14 Novoseek inferred disease relationships for LAMA3 gene (see all 14) About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
epidermolysis bullosa junctional	96.5	15	9759651 (2), 8530087 (2), 10469327 (1), 12915477 (1) (see all 13)
lethal junctional epidermolysis bullosa	84.7	1	9027848 (1)
epidermolysis bullosa	78.1	1	7550237 (1)
pemphigoid cicatricial	72.9	1	12746470 (1)
epidermolysis bullosa acquisita	62	2	10677099 (1), 12746470 (1)
skin diseases	50.8	7	8618058 (1), 9759651 (1), 8618020 (1), 8530087 (1) (see all 7)
pemphigoid bullous	40.2	1	12746470 (1)
carcinoma squamous cell	17	1	11267939 (1)
necrosis	0	1	7635220 (1)
breast cancer	0	5	11551969 (3), 14695139 (2)

GeneTests: LAMA3

Junctional Epidermolysis Bullosa

Genetic Association Database (GAD): LAMA3
Human Genome Epidemiology (HuGE) Navigator: LAMA3 (9 documents)

Export disorders for LAMA3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for LAMA3 gene, integrated from 9 sources (see all 174):
(articles sorted by number of sources associating them with LAMA3)

Utopia: connect your pdf to the dynamic
world of online information

Cloning of the LamA3 gene encoding the alpha 3 chain of the adhesive ligand epiligrin. Expression in wound repair. (PubMed id 8077230)^{1, 2, 3, 9} Ryan M.C.... Carter W.G. (1994)
Cloning of the laminin alpha 3 chain gene (LAMA3) and identification of a homozygous deletion in a patient with Herlitz junctional epidermolysis bullosa. (PubMed id 8586427)^{1, 2, 9} Vidal F.... Meneguzzi G. (1995)
An unusual N-terminal deletion of the laminin alpha3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome. (PubMed id 12915477)^{1, 2, 9} McLean W.H.I.... McGrath J.A. (2003)
Genetic risk for myocardial infarction in Japanese in dividuals with or without chronic kidney disease. (PubMed id 20372818)^{1, 4} Fujimaki T....Yamada Y. (2010)
Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)^{1, 4} Yoshida T....Yamada Y. (2010)
Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)^{1, 4} Oguri M....Yamada Y. (2010)
Association of gene polymorphisms with chronic kidney disease in Japanese individuals. (PubMed id 19724895)^{1, 4} Yoshida T....Yamada Y. (2009)
Sequential use of transcriptional profiling, expressi on quantitative trait mapping, and gene association implicates MMP20 in human k idney aging. (PubMed id 19834535)^{1, 4} Wheeler H.E....Kim S.K. (2009)
Characterization of laminin 5B and NH2-terminal proteolytic fragment of its alpha3B chain: promotion of cellular adhesion, migration, and proliferation. (PubMed id 15044476)^{1, 2} Kariya Y....Miyazaki K. (2004)
Molecular analysis of the human laminin alpha3a chain gene (LAMA3a): a strategy for mutation identification and DNA-based prenatal diagnosis in Herlitz junctional epidermolysis bullosa. (PubMed id 9759651)^{1, 9} Pulkkinen L....Christiano A.M. (1998)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 3909	HGNC: 6483	AceView: LAMA3	Ensembl:ENSG00000053747	euGenes: HUgn3909
ECgene: LAMA3	Kegg: 3909	H-InvDB: LAMA3

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for LAMA3	Pharmacogenomics, SNPs, Pathways
GeneReviews	http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/LAMA3

Intellectual Property for LAMA3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for LAMA3 gene:
Search GeneIP for patents involving LAMA3

Licensable Technologies for LAMA3 gene:

Tufts University:

Laminins and their functions in nervous systems

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Antibodies for LAMA3 (Laminin alpha 3/Laminin-5)		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Protease Activity Assays and Reagents		Browse Recombinant/Natural Proteins
	Browse Stem Cell Products		Browse Tocris Biochemicals & Compounds
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for LAMA3
	Browse OriGene qPCR primer pairs and template standards		OriGene Protein Over-expression Lysate for LAMA3
	OriGene Custom Mass Spec		OriGene clones in human, mouse for LAMA3
	OriGene qSTAR qPCR primer pairs in human, mouse for LAMA3		Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
	OriGene ORF clones in mouse, rat for LAMA3		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for LAMA3		OriGene Custom Protein Services for LAMA3

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat LAMA3
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LAMA3
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LAMA3
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LAMA3
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LAMA3
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LAMA3

	GenScript Custom Purified and Recombinant Proteins Services for LAMA3		GenScript cDNA clones with any tag delivered in your preferred vector for LAMA3
	GenScript Custom Assay Services for LAMA3		GenScript Custom Superior Antibodies Services for LAMA3
	GenScript Custom overexpressing Cell Line Services for LAMA3		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in LAMA3 promoter
	Search Chromatin IP Primers for LAMA3
	RT² qPCR Primer Assay in human, mouse, rat LAMA3
	GNC Network for LAMA3
	SABiosciences PCR Arrays including human, mouse, rat LAMA3

Search Tocris compounds for LAMA3

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological Cell Lysates
	Browse Sino Biological cDNA Clones
	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	LAMA3 antibodies
	LAMA3 proteins
	LAMA3 lysates

	Antibodies for LAMA3
	See all of Abcam's Antibodies, Kits and Proteins for LAMA3
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Browse Proteins at Cloud-Clone Corp.
	Browse Antibodies at Cloud-Clone Corp.
	Browse ELISAs at Cloud-Clone Corp.
	Browse CLIAs at Cloud-Clone Corp.

Search LifeMap BioReagents cell lines for LAMA3

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LAMA3

	SwitchGear 3'UTR luciferase reporter plasmids for LAMA3
	SwitchGear Promoter luciferase reporter plasmids for LAMA3

Search ThermoFisher Antibodies for LAMA3

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LAMA3

	inGenious Targeting Laboratory - Custom generated mouse model solutions for LAMA3
	inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for LAMA3

Customized:

	stable knockdown cell line services for LAMA3
	inducible knockdown cell line services for LAMA3
	design and validation of potent shRNA sequences against LAMA3
	adenovirus for potent knockdown of LAMA3
	stable overexpressing cell line services
	inducible overexpressing cell line services
	adenovirus for overexpression

LSBio Antibodies in human, mouse, rat for LAMA3

GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013

View Random Gene

Category			TGFB1 (GIFtS: 73) transforming growth factor, beta 1
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes LAMA3 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

LAMA3 Gene

Laminin, Alpha 3

Aliases
for LAMA3 gene

Summaries
for LAMA3 gene

Genomic Views
for LAMA3 gene

Proteins
for LAMA3 gene

Protein Domains /
Families
for LAMA3 gene

Function
for LAMA3 gene

Pathways & Interactions
for LAMA3 gene

Drugs & Compounds
for LAMA3 gene

Transcripts
for LAMA3 gene

Expression
for LAMA3 gene

Orthologs
for LAMA3 gene

Paralogs
for LAMA3 gene

Genomic Variants
for LAMA3 gene

Disorders / Diseases
for LAMA3 gene

Publications
for LAMA3 gene

External Searches for LAMA3 gene

Genome Databases showing LAMA3 gene

Other Databases showing LAMA3 gene

Specialized Databases showing LAMA3 gene

Intellectual Property
for LAMA3 gene

Products
for LAMA3 gene

View Random Gene

LAMA3 (Gene Symbol)
Laminin, Alpha 3
LAMNA
Laminin, Alpha 3 (Nicein (150kD), Kalinin (165kD), BM600 (150kD), Epilegrin)
Epiligrin 170 KDa Subunit
Epiligrin Subunit Alpha
Kalinin Subunit Alpha
Laminin-5 Subunit Alpha
Laminin-6 Subunit Alpha
Laminin-7 Subunit Alpha
Nicein Subunit Alpha
E170
LOCS
BM600
BM600 150kD Subunit
Epiligrin Alpha 3 Subunit
Kalinin 165kD Subunit
lama3a
Laminin Subunit Alpha-3
Laminin-5 Alpha 3 Chain
Nicein 150kD Subunit

Advanced Search

Export list of displayed genes

LAMA3 Gene

Laminin, Alpha 3

Aliasesfor LAMA3 gene

Summariesfor LAMA3 gene

Genomic Viewsfor LAMA3 gene

Proteinsfor LAMA3 gene

Protein Domains /Familiesfor LAMA3 gene

Functionfor LAMA3 gene

Pathways & Interactionsfor LAMA3 gene

Drugs & Compoundsfor LAMA3 gene

Transcriptsfor LAMA3 gene

Expression for LAMA3 gene

Orthologsfor LAMA3 gene

Paralogsfor LAMA3 gene

Genomic Variantsfor LAMA3 gene

Disorders / Diseasesfor LAMA3 gene

Publicationsfor LAMA3 gene

External Searches for LAMA3 gene

Genome Databases showing LAMA3 gene

Other Databases showing LAMA3 gene

Specialized Databases showing LAMA3 gene

Intellectual Propertyfor LAMA3 gene

Productsfor LAMA3 gene

View Random Gene

Aliases
for LAMA3 gene

Summaries
for LAMA3 gene

Genomic Views
for LAMA3 gene

Proteins
for LAMA3 gene

Protein Domains /
Families
for LAMA3 gene

Function
for LAMA3 gene

Pathways & Interactions
for LAMA3 gene

Drugs & Compounds
for LAMA3 gene

Transcripts
for LAMA3 gene

Expression
for LAMA3 gene

Orthologs
for LAMA3 gene

Paralogs
for LAMA3 gene

Genomic Variants
for LAMA3 gene

Disorders / Diseases
for LAMA3 gene

Publications
for LAMA3 gene

Intellectual Property
for LAMA3 gene

Products
for LAMA3 gene