Aliases for LAMA1 Gene
Aliases for LAMA1 Gene
External Ids for LAMA1 Gene
- HGNC: 6481
- Entrez Gene: 284217
- Ensembl: ENSG00000101680
- OMIM: 150320
- UniProtKB: P25391
Previous HGNC Symbols for LAMA1 Gene
- LAMA
Previous GeneCards Identifiers for LAMA1 Gene
- GC18M006877
- GC18M007006
- GC18M006931
- GC18M006905
Summaries for LAMA1 Gene
-
This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene may be associated with Poretti-Boltshauser syndrome. [provided by RefSeq, Sep 2014]
GeneCards Summary for LAMA1 Gene
LAMA1 (Laminin Subunit Alpha 1) is a Protein Coding gene. Diseases associated with LAMA1 include Poretti-Boltshauser Syndrome and Ataxia-Intellectual Disability-Oculomotor Apraxia-Cerebellar Cysts Syndrome. Among its related pathways are ERK Signaling and Cell adhesion_Endothelial cell contacts by non-junctional mechanisms. GO annotations related to this gene include receptor binding and glycosphingolipid binding. An important paralog of this gene is LAMC2.
UniProtKB/Swiss-Prot for LAMA1 Gene
-
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LAMA1 Gene
Genomics for LAMA1 Gene
Regulatory Elements for LAMA1 Gene
Enhancers for LAMA1 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around LAMA1 on UCSC Golden Path with GeneCards custom track
Promoters for LAMA1 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around LAMA1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for LAMA1 Gene
- Chromosome:
- 18
- Start:
- 6,941,744 bp from pter
- End:
- 7,117,814 bp from pter
- Size:
- 176,071 bases
- Orientation:
- Minus strand
Genomic View for LAMA1 Gene
Genes around LAMA1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 18p11.31 by Ensembl
- 18p11.3 by Entrez Gene
- 18p11.3 by HGNC
LAMA1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for LAMA1 Gene
Proteins for LAMA1 Gene
-
Protein details for LAMA1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P25391-LAMA1_HUMAN
- Recommended name:
- Laminin subunit alpha-1
- Protein Accession:
- P25391
Protein attributes for LAMA1 Gene
- Size:
- 3075 amino acids
- Molecular mass:
- 337084 Da
- Quaternary structure:
-
- Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Alpha-1 is a subunit of laminin-1 (laminin-111 or EHS laminin) and laminin-3 (laminin-121 or S-laminin).
Protein Expression for LAMA1 Gene
Post-translational modifications for LAMA1 Gene
- Tyrosine phosphorylated by PKDCC/VLK.
- Glycosylation at Asn 38, Asn 555, Asn 665, Asn 763, Asn 926, Asn 952, Asn 1045, Asn 1407, Asn 1579, Asn 1596, Asn 1678, Asn 1689, Asn 1698, Asn 1717, Asn 1804, Asn 1894, Asn 1898, Asn 1957, Asn 1974, Asn 1991, Asn 2038, Asn 2047, Asn 2094, Asn 2098, Asn 2243, Asn 2244, Asn 2384, Asn 2408, Asn 2518, Asn 2619, Asn 2729, Asn 2852, Asn 2915, and Asn 2983
- Modification sites at PhosphoSitePlus
Other Protein References for LAMA1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for LAMA1
- R&D Systems Antibodies for LAMA1 (Laminin alpha 1)
- Novus Biologicals Antibodies for LAMA1
-
Cloud-Clone Corp. Antibodies for LAMA1
- Invitrogen Antibodies for LAMA1
- antibodies-online Antibodies for LAMA1: See all 62
- GeneTex LAMA1 antibody for LAMA1
-
Santa Cruz Biotechnology (SCBT) Antibodies for LAMA1
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for LAMA1
- Origene Custom Protein Services for LAMA1
- Novus Biologicals proteins for LAMA1
-
Cloud-Clone Corp. Proteins for LAMA1
- antibodies-online Proteins for LAMA1: See all 13
- Search antibodies-online for peptides
- Search GeneTex for Proteins for LAMA1
Assay Products
- antibodies-online Kits for LAMA1: See all 6
No data available for DME Specific Peptides for LAMA1 Gene
Domains & Families for LAMA1 Gene
Gene Families for LAMA1 Gene
- HGNC:
Protein Domains for LAMA1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for LAMA1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P25391UniProtKB/Swiss-Prot:
LAMA1_HUMAN :- The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.
- Domain:
-
- The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.
- Domains VI, IV and G are globular.
- Contains 17 laminin EGF-like domains.
- Contains 5 laminin G-like domains.
- Contains 2 laminin IV type A domains.
- Contains 1 laminin N-terminal domain.
Function for LAMA1 Gene
Molecular function for LAMA1 Gene
- GENATLAS Biochemistry:
- laminin,alpha 1 polypeptide,component of cutaneous basement membrane zone
- UniProtKB/Swiss-Prot Function:
- Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Phenotypes for LAMA1 Gene
- MGI mutant phenotypes for LAMA1:
- inferred from 8 alleles
- GenomeRNAi human phenotypes for LAMA1:
Animal Models for LAMA1 Gene
Animal Model Products
-
Taconic Biosciences Mouse Models for LAMA1
-
ViGene Biosciences lentiviral particle packaged cDNA for LAMA1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for LAMA1 gene
- Search ViGene Biosciences for LAMA1
CRISPR Products
-
OriGene CRISPR knockouts for LAMA1
-
Santa Cruz Biotechnology (SCBT) CRISPR for LAMA1
- GenScript: Design CRISPR guide RNA sequences for LAMA1
miRNA for LAMA1 Gene
- miRTarBase miRNAs that target LAMA1
miRNA Products
- Search ViGene Biosciences for LAMA1
Clone Products
- OriGene clones in human for LAMA1
- OriGene ORF clones in human,rat for LAMA1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for LAMA1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for LAMA1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for LAMA1 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Transcription Factor Targets and HOMER Transcription for LAMA1 Gene
Localization for LAMA1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for LAMA1 Gene
- Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| cytosol | 2 |
| plasma membrane | 2 |
| lysosome | 1 |
| peroxisome | 1 |
| vacuole | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005578 | proteinaceous extracellular matrix | ISS | -- |
| GO:0005606 | laminin-1 complex | IPI | 10964500 |
Pathways & Interactions for LAMA1 Gene
More details on SuperPathways for LAMA1| Superpath | Contained pathways | ||
|---|---|---|---|
| 1 | Integrin Pathway |
.67
.67
.56
|
.56
|
| 2 | ERK Signaling |
.61
.58
|
.49
|
| 3 | Focal Adhesion |
.62
|
.62
|
| 4 | Blood-Brain Barrier and Immune Cell Transmigration: Pathways Overview | ||
| 5 | Phospholipase-C Pathway |
.56
|
Pathways by source for LAMA1 Gene
5 BioSystems pathways for LAMA1 Gene
7 Reactome pathways for LAMA1 Gene
7 KEGG pathways for LAMA1 Gene
6 GeneGo (Thomson Reuters) pathways for LAMA1 Gene
2 R&D Systems pathways for LAMA1 Gene
14 Qiagen pathways for LAMA1 Gene
Interacting Proteins for LAMA1 Gene
Selected Interacting proteins:
P25391-LAMA1_HUMAN
ENSP00000374309
for LAMA1 Gene via
MINT
STRING
UniProtKB
I2D
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007411 | axon guidance | TAS | -- |
| GO:0030334 | regulation of cell migration | IEA | -- |
Drugs & Compounds for LAMA1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| 3-O-Sulfogalactosylceramide (d18:1/24:0) |
|
151122-71-3 |
|
Transcripts for LAMA1 Gene
mRNA/cDNA for LAMA1 Gene
- (4) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (2) Selected AceView cDNA sequences:
- (8) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for LAMA1
-
Santa Cruz Biotechnology (SCBT) CRISPR for LAMA1
- GenScript: Design CRISPR guide RNA sequences for LAMA1
miRNA Products
- Search ViGene Biosciences for LAMA1
Clone Products
- OriGene clones in human for LAMA1
- OriGene ORF clones in human,rat for LAMA1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22a | · | 22b | ^ | 23 | ^ | 24 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: |
| ExUns: | 25a | · | 25b | ^ | 26 | ^ | 27 | ^ | 28a | · | 28b | ^ | 29a | · | 29b | · | 29c | ^ | 30 | ^ | 31 | ^ | 32a | · | 32b | ^ | 33 | ^ | 34 | ^ | 35 | ^ | 36a | · | 36b | ^ | 37 | ^ | 38 | ^ | 39 | ^ | 40 | ^ | 41 | ^ | 42 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP12: |
Expression for LAMA1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Kidney (Urinary System)
- S-shaped Body Cells S-shaped Body
- Angioblasts S-shaped Body
- Podocytes Podocyte Layer
- Renal Vesicle
- S-shaped Body
-
Tooth (Integumentary System)
- Dental Papilla Cells Dental Papilla
- Dentin
-
Trophoblast (Extraembryonic Tissues)
- Trophoblast Cells Trophoblast
- Mural Trophectoderm Cells Mural Trophectoderm
-
Gonad (Reproductive System)
- Testis Somatic Cells Primitive Gonad
-
Testis (Reproductive System)
- Testis Somatic Cells Primitive Gonad
-
Limb (Muscoskeletal System)
- Apical Ectodermal Ridge Cells Limb Ectoderm
-
Ectoderm (Gastrulation Derivatives)
- Apical Ectodermal Ridge Cells Limb Ectoderm
-
Eye (Sensory Organs)
- Lens Vesicle Cells Lens Vesicle
-
Endothelium (Cardiovascular System)
- Angioblasts S-shaped Body
-
Mesoderm (Gastrulation Derivatives)
- Mesothelial Cells Hepatic Mesenchyme
-
Liver (Hepatobiliary System)
- Mesothelial Cells Hepatic Mesenchyme
-
Heart (Cardiovascular System)
- Subepicardial Cells Epicardium
-
Epithelial Cells
- Podocytes Podocyte Layer
- Inner Cell Mass (Early Embryonic Tissues)
- NULL (Uncategorized)
- Hypoblast (Extraembryonic Tissues)
mRNA differential expression in normal tissues according to GTEx for LAMA1 Gene
This gene is overexpressed in Testis (x7.5).
This gene is overexpressed in Amniocyte (33.8) and Ovary (8.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for LAMA1 Gene
SOURCE GeneReport for Unigene cluster for LAMA1 Gene Hs.270364
Primer Products
-
OriGene qPCR primer pairs for LAMA1
No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for LAMA1 Gene
Orthologs for LAMA1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | LAMA1 35 |
|
||
| LAMA1 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | LAMA1 35 |
|
||
| LAMA1 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Lama1 35 |
|
||
| Lama1 16 |
|
||||
| Lama1 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | LAMA1 35 |
|
||
| LAMA1 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Lama1 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | LAMA1 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | LAMA1 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | LAMA1 35 |
|
||
| LAMA1 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | LAMA1 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | lama1 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | lama1 35 |
|
||
| lama1 36 |
|
OneToOne | |||
| fruit fly (Drosophila melanogaster) |
Insecta | wb 36 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | lam-3 36 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 36 |
|
OneToMany |
- Species with no ortholog for LAMA1:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for LAMA1 Gene
Paralogs for LAMA1 Gene
(7) SIMAP similar genes for LAMA1 Gene using alignment to 5 proteins:
Variants for LAMA1 Gene
| SNP ID | Clin | Chr 18 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs9950267 | - | 7,043,336(+) | TATTC(A/G)AACTT | reference, missense | |
| rs16951079 | - | 7,037,640(+) | CATGA(C/T)CGCGG | reference, missense | |
| rs12961939 | - | 6,997,819(+) | CAGAG(A/C)AAGAA | reference, missense | |
| rs596315 | - | 6,997,777(+) | TGACA(A/C/G)AATTC | reference, missense | |
| rs11872364 | - | 6,995,359(+) | TACCT(C/T)CTTTT | reference, missense |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1009e1 | CNV | Complex | 17122850 |
| nsv833583 | CNV | Gain | 17160897 |
| nsv7302 | OTHER | Inversion | 18451855 |
| esv2716743 | CNV | Deletion | 23290073 |
| esv2716744 | CNV | Deletion | 23290073 |
| nsv909338 | CNV | Gain | 21882294 |
| nsv526300 | CNV | Loss | 19592680 |
| esv1010298 | CNV | Loss | 20482838 |
| esv2716745 | CNV | Deletion | 23290073 |
| esv1060234 | CNV | Deletion | 17803354 |
| nsv909339 | CNV | Gain | 21882294 |
| dgv3380n71 | CNV | Gain | 21882294 |
| dgv3381n71 | CNV | Gain | 21882294 |
| esv2671013 | CNV | Deletion | 23128226 |
| esv1093980 | CNV | Deletion | 17803354 |
| esv22796 | CNV | Gain | 19812545 |
Residual Variation Intolerance Score:
91.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
17.42;
98.19% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for LAMA1 Gene
- Human Gene Mutation Database (HGMD)
- LAMA1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LAMA1 Gene
Disorders for LAMA1 Gene
(3) MalaCards diseases for LAMA1 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| poretti-boltshauser syndrome |
|
|
| ataxia-intellectual disability-oculomotor apraxia-cerebellar cysts syndrome |
|
|
| myopia |
|
|
Search LAMA1 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
LAMA1_HUMAN- Poretti-Boltshauser syndrome (PTBHS) [MIM:615960]: An autosomal recessive disorder characterized by cerebellar dysplasia, cerebellar vermis atrophy, cerebellar cysts in most patients, high myopia, variable retinal dystrophy, and eye movement abnormalities including strabismus, ocular apraxia, nystagmus. Affected individuals have ataxia, delayed motor development, language impairment, and intellectual disability with variable severity. {ECO:0000269 PubMed:25105227}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for LAMA1
No data available for Genatlas for LAMA1 Gene
Publications for LAMA1 Gene
- Primary structure of the human laminin A chain. Limited expression in human tissues. (PMID: 2049067) Nissinen M. … Tryggvason K. (Biochem. J. 1991) 3 4 23 67
- The extracellular matrix proteins laminin and fibronectin contain binding domains for human plasminogen and tissue plasminogen activator. (PMID: 8360181) Moser T.L. … Stack M.S. (J. Biol. Chem. 1993) 3 23
- Molecular cloning of the cDNA encoding human laminin A chain. (PMID: 1714537) Haaparanta T. … Engvall E. (Matrix 1991) 3 23
- Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits. (PMID: 2099832) Engvall E. … Sanes J.R. (Cell Regul. 1990) 3 23
- Sulfatide-binding domain of the laminin A chain. (PMID: 2373692) Taraboletti G. … Roberts D.D. (J. Biol. Chem. 1990) 3 23
Products for LAMA1 Gene
- R&D Systems Antibodies for LAMA1 (Laminin alpha 1)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Browse ELISpot/FluoroSpot Kits and Development Modules
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- Browse Immunoprecipitation Assays
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- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for LAMA1
- Origene Custom Protein Services for LAMA1
- Origene siRNA, shRNA, mouse_rna, rat_shrna, and RNAi products in human, mouse, rat for LAMA1
- Browse OriGene Inhibitory RNA Products For LAMA1
- OriGene qPCR primer pairs for LAMA1
- OriGene CRISPR knockouts for LAMA1
- OriGene clones in human for LAMA1
- OriGene ORF clones in human,rat for LAMA1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for LAMA1
- GenScript Custom Assay Services for LAMA1
- GenScript Custom overexpressing Cell Line Services for LAMA1
- GenScript: Design CRISPR guide RNA sequences for LAMA1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for LAMA1
- Novus Biologicals Antibodies for LAMA1
- Novus Biologicals proteins for LAMA1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cloud-Clone Corp. Antibodies for LAMA1
- Cloud-Clone Corp. Proteins for LAMA1
- Browse Assay Kits at Cloud-Clone Corp.
- Taconic Biosciences Mouse Models for LAMA1
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- antibodies-online Antibodies for LAMA1: See all 62
- antibodies-online Kits for LAMA1: See all 6
- antibodies-online Proteins for LAMA1: See all 13
- Search antibodies-online for peptides
- GeneTex LAMA1 antibody for LAMA1
- Search GeneTex for Proteins for LAMA1
- ViGene Biosciences adenoviral particle packaged cDNA for LAMA1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for LAMA1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for LAMA1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for LAMA1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for LAMA1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for LAMA1 gene
- Search ViGene Biosciences for LAMA1
- Search ViGene Biosciences for LAMA1
- Santa Cruz Biotechnology (SCBT) Antibodies for LAMA1
- Search Santa Cruz Biotechnology (SCBT) for LAMA1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for LAMA1
Sources for LAMA1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
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- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
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- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
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- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
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- (129) SIGNOR
- (130) diseasecard
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- (139) CDC
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- (141) NCBI Bookshelf
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- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon