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Aliases for LACTBL1 Gene

Aliases for LACTBL1 Gene

  • Lactamase Beta Like 1 2 3 5

External Ids for LACTBL1 Gene

Previous GeneCards Identifiers for LACTBL1 Gene

  • GC01M023279
  • GC01M021523

Summaries for LACTBL1 Gene

GeneCards Summary for LACTBL1 Gene

LACTBL1 (Lactamase Beta Like 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LACTBL1 Gene

Genomics for LACTBL1 Gene

Regulatory Elements for LACTBL1 Gene

Enhancers for LACTBL1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G023187 1.5 Ensembl ENCODE dbSUPER 17.1 -216.6 -216628 3.2 FOXA2 MLX ARID4B DMAP1 ZNF48 YY1 ZNF143 FOS NFYC MIER2 LACTBL1 LUZP1 RNU6-135P RNU6-514P HTR1D
GH01G023010 1 Ensembl ENCODE 21.6 -38.5 -38523 1.6 SCRT1 KLF1 SMARCC1 TAF1 JUN NR3C1 ZNF121 JUND EED SCRT2 LACTBL1 GC01P023012 GC01P022984
GH01G023098 1.9 FANTOM5 Ensembl ENCODE dbSUPER 11 -129.5 -129523 6.8 HDGF PKNOX1 ARNT ZFP64 WRNIP1 ARID4B ZNF2 ZNF143 FOS REST LUZP1 RNU6-514P RNU6-135P LACTBL1 GC01M023095 ENSG00000229010
GH01G023018 1.2 ENCODE 15.1 -47.6 -47609 3.0 CREB3L1 MLX ZFP64 FEZF1 DMAP1 YY1 ZNF143 ZNF263 SP3 NFYC LACTBL1 CDC42-IT1 HTR1D KDM1A MIR3115
GH01G022976 1.2 Ensembl ENCODE 12.5 -4.3 -4337 1.3 HDGF ATF1 ARNT SIN3A YY1 ZNF121 GATA2 ZNF143 ZNF207 KLF7 LACTBL1 LUZP1 GC01P022984
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around LACTBL1 on UCSC Golden Path with GeneCards custom track

Genomic Location for LACTBL1 Gene

22,953,043 bp from pter
22,972,316 bp from pter
19,274 bases
Minus strand

Genomic View for LACTBL1 Gene

Genes around LACTBL1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LACTBL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LACTBL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LACTBL1 Gene

Proteins for LACTBL1 Gene

  • Protein details for LACTBL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative beta-lactamase-like 1
    Protein Accession:

    Protein attributes for LACTBL1 Gene

    500 amino acids
    Molecular mass:
    54653 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LACTBL1 Gene

Post-translational modifications for LACTBL1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for LACTBL1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for LACTBL1 Gene

Domains & Families for LACTBL1 Gene

Protein Domains for LACTBL1 Gene

Suggested Antigen Peptide Sequences for LACTBL1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the beta-lactamase family.
  • Belongs to the beta-lactamase family.
genes like me logo Genes that share domains with LACTBL1: view

No data available for Gene Families for LACTBL1 Gene

Function for LACTBL1 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LACTBL1 Gene

Localization for LACTBL1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LACTBL1 gene
Compartment Confidence
peroxisome 2
nucleus 2
cytosol 2
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for LACTBL1 Gene

Pathways & Interactions for LACTBL1 Gene

SuperPathways for LACTBL1 Gene

No Data Available

Interacting Proteins for LACTBL1 Gene

Gene Ontology (GO) - Biological Process for LACTBL1 Gene


No data available for Pathways by source and SIGNOR curated interactions for LACTBL1 Gene

Drugs & Compounds for LACTBL1 Gene

No Compound Related Data Available

Transcripts for LACTBL1 Gene

mRNA/cDNA for LACTBL1 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for LACTBL1 Gene

No ASD Table

Relevant External Links for LACTBL1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for LACTBL1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LACTBL1 Gene

mRNA differential expression in normal tissues according to GTEx for LACTBL1 Gene

This gene is overexpressed in Testis (x53.0).

Protein differential expression in normal tissues from HIPED for LACTBL1 Gene

This gene is overexpressed in Gallbladder (35.7), Heart (26.7), and Retina (6.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for LACTBL1 Gene

Protein tissue co-expression partners for LACTBL1 Gene

NURSA nuclear receptor signaling pathways regulating expression of LACTBL1 Gene:

genes like me logo Genes that share expression patterns with LACTBL1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LACTBL1 Gene

Orthologs for LACTBL1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for LACTBL1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LACTBL1 34
  • 92.44 (n)
(Canis familiaris)
Mammalia LACTBL1 35 34
  • 90.29 (n)
(Bos Taurus)
Mammalia LACTBL1 34 35
  • 88.6 (n)
(Mus musculus)
Mammalia Lactbl1 34 16 35
  • 79.16 (n)
(Monodelphis domestica)
Mammalia LACTBL1 35
  • 72 (a)
(Ornithorhynchus anatinus)
Mammalia LACTBL1 35
  • 68 (a)
(Gallus gallus)
Aves LACTBL1 34 35
  • 67.21 (n)
(Anolis carolinensis)
Reptilia LACTBL1 35
  • 67 (a)
(Danio rerio)
Actinopterygii lactbl1b 34 35
  • 59.94 (n)
lactbl1a 35
  • 57 (a)
Species where no ortholog for LACTBL1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for LACTBL1 Gene

Gene Tree for LACTBL1 (if available)
Gene Tree for LACTBL1 (if available)

Paralogs for LACTBL1 Gene

No data available for Paralogs for LACTBL1 Gene

Variants for LACTBL1 Gene

Sequence variations from dbSNP and Humsavar for LACTBL1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000174599 -- 22,971,744(+) TCTGC(C/T)GTTAC intron-variant
rs1000222357 -- 22,972,455(+) GACAG(A/C)GAAAA upstream-variant-2KB
rs1000253273 -- 22,957,290(+) AGCCT(C/T)TTGCT intron-variant
rs1000271883 -- 22,962,365(+) TCCCC(A/C)ACCAT intron-variant
rs1000464006 -- 22,968,687(+) CTGAT(C/T)TGCAA intron-variant

Variation tolerance for LACTBL1 Gene

Gene Damage Index Score: 10.93; 91.93% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for LACTBL1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for LACTBL1 Gene

Disorders for LACTBL1 Gene

Relevant External Links for LACTBL1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for LACTBL1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LACTBL1 Gene

Publications for LACTBL1 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64

Products for LACTBL1 Gene

Sources for LACTBL1 Gene

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