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L2HGDH Gene

protein-coding GIFtS: 50

GC14M049775

L-2-hydroxyglutarate dehydrogenase
(Previous name: chromosome 14 open reading frame 160 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: C14orf160)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
C14orf160 ^², ³, ⁵
DURANIN ^²
Duranin ^³
EC 1.1.99.2 ^³
FLJ12618 ^¹, ²

Descriptions
2-hydroxyglutarate dehydrogenase ^²
L-2-hydroxyglutarate dehydrogenase ^²
L-alpha-hydroxyglutarate dehydrogenase ^²
alpha-hydroxyglutarate oxidoreductase ^²
alpha-ketoglutarate reductase ^²
chromosome 14 open reading frame 160 ^¹

External Ids
HGNC: 20499¹
Entrez Gene: 79944²
UniProtKB: Q9H9P8³
Ensembl: ENSG00000087299⁷

Search outside databases for aliases for L2HGDH gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for L2HGDH:

This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes

L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this

gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder

resulting in moderate to severe mental retardation. [provided by RefSeq]

Gene Wiki entry for L2HGDH

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the L2HGDH gene

Entrez Gene cytogenetic band: 14q22.1 Ensembl cytogenetic band: 14q22.1 HGNC cytogenetic band: 14q22.1

L2HGDH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 14 GeneLoc Exon Structure

GeneLoc location for GC14M049775: (about GC identifiers)

Start:	49,774,064 bp from pter
End:	49,848,697 bp from pter
Size:	74,634 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000014.7 NT_026437.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: L2HDH_HUMAN, Q9H9P8 (See protein sequence)

Recommended Name: L-2-hydroxyglutarate dehydrogenase, mitochondrial precursor

Size: 463 amino acids; 50359 Da

Cofactor: FAD

Subcellular location: Mitochondrion

Miscellaneous: Was named 'duranin' in honor of Marinus Duran, who first described

L-2-hydroxyglutaric aciduria

Secondary accessions: Q9BRR1

Alternative splicing: 2 isoforms: Q9H9P8-1 Q9H9P8-2

REFSEQ proteins: NP_079160.1

ENSEMBL proteins:

ENSP00000267436 ENSP00000261699

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
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	Browse Abcam for Recombinant Proteins
	Human Recombinant Proteins from Abnova (L2HGDH)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005739	mitochondrion	IDA	16005139
GO:0016021	integral to membrane	IDA	16005139
GO:0031305	integral to mitochondrial inner membrane	NAS	16005139

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Antibodies for L2HGDH:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for L2HGDH

Assays for L2HGDH:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry Q9H9P8

ProtoNet protein and cluster: Q9H9P8

UniProtKB/Swiss-Prot: L2HDH_HUMAN, Q9H9P8

Similarity: Belongs to the L2HGDH family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (L2HGDH)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): BC006117

Applied Biosystems Silencer® siRNAs for L2HGDH

Sigma-Aldrich siRNA for L2HGDH

Sigma-Aldrich shRNA for L2HGDH

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for L2HGDH
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_024884
Myc/DDK tagged cDNA clone in CMV expression vector: NM_024884
untagged cDNA clones in CMV expression vector (see all 2): BC006117

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_024884

UniProtKB/Swiss-Prot: L2HDH_HUMAN, Q9H9P8

Catalytic activity: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor

Biophysicochemical properties: Kinetic parameters: KM=800 uM for L-2-hydroxyglutarate;

Enzyme Number (IUBMB): EC 1.1.99.2

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016491	oxidoreductase activity	IEA	--
GO:0047545	2-hydroxyglutarate dehydrogenase activity	IDA	16005139

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for L2HGDH (Your Favorite Gene powered by Ingenuity)

Butanoate Metabolism

GeneDecks L2HGDH for the pathways selected above

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5/20 Interacting proteins for L2HGDH (ENSP00000267436³) via UniProtKB, MINT, and/or STRING (see all 20 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CS	ENSP00000342056³	STRING (score=.899)
FH	ENSP00000355518³	STRING (score=.899)
ADC	ENSP00000362540³	STRING (score=.8)
ALDH4A1	ENSP00000290597³	STRING (score=.8)
EARS2	ENSP00000343488³	STRING (score=.8)

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2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0044267	cellular protein metabolic process	IDA	16005139
GO:0055114	oxidation reduction	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for L2HGDH

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (L2HGDH)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): BC006117

Sigma-Aldrich siRNA for L2HGDH

Sigma-Aldrich shRNA for L2HGDH

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_024884

REFSEQ mRNAs for L2HGDH gene:

NM_024884.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_024884

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_024884
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_024884
                                 untagged cDNA clones in CMV expression vector (see all 2): BC006117

Additional cDNA sequence:

AK022680.1 AK292627.1 AK309294.1 AY757363.1 BC006117.1

7 DOTS entries:

DT.40219587 DT.95265298 DT.40300804 DT.120765684 DT.91728482 DT.91739526 DT.97807645

24/36 AceView cDNA sequences (see all 36 ):

AA583482 BE294650 BM807046 AA555323 BE279451 BU601550 BC006117 BX280761

BE883619 BF034867 BE878762 AU125485 BI917205 BQ775984 AA937054 BM462381

BQ050387 BG421960 BP431818 AK022680 NM_024884 BU189807 BG824975 BI333616

highest scoring ESTs for L2HGDH:

AK022680 AU125485 BC006117 BE279451 BE294650 BE883619 BG824975 BI333616 BM807046 BQ050387

Unigene Cluster for L2HGDH:

L-2-hydroxyglutarate dehydrogenase

Hs.256034 [show with all ESTs]

Unigene Representative Sequence: NM_024884

GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:

ENST00000267436 ENST00000261699

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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L2HGDH expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for L2HGDH

¹ / ² / ³

8 probe-sets matching L2HGDH gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
70870_r_at²^{, 3}	U95-E	1	1.00	1.00	0.82	0.94	AI796129	0.40	1.00	0.76	1
72497_at²^{, 3}	U95-D	1	0.56	1.00	0.87	1.08	AA555323	0.60	1.00	0.82	1
224460_s_at²^{, 3}	U133-B	1	1.00	1.00	--	--	BC006117	0.80	1.00	0.91	1
224459_at²^{, 3}	U133-B	1	1.00	1.00	--	--	BC006117	0.80	1.00	0.91	1
220089_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_024884	0.60	1.00	0.82	1
224460_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
224459_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
220089_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GTGTCTATAT

SOURCE GeneReport for Unigene cluster: Hs.256034
UniProtKB/Swiss-Prot: L2HDH_HUMAN, Q9H9P8
Tissue specificity: Widely expressed. Highly expressed in brain, testis and muscle. Expressed to a
lower extent in lymphocytes, fibroblasts, keratinocytes, placenta, bladder, small intestine, liver
and bone marrow

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for L2HGDH gene from 5/12 species (see all 12 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	L2HGDH¹	--	L-2-hydroxyglutarate dehydrogenase	91.07(n) 89.2(a)	480316 XM_537438.2 XP_537438.2
chimpanzee (Pan troglodytes)	L2HGDH¹	--	L-2-hydroxyglutarate dehydrogenase	99.14(n) 98.49(a)	452898 XM_509940.2 XP_509940.1
cow (Bos taurus)	L2HGDH¹	--	L-2-hydroxyglutarate dehydrogenase	90.28(n) 88.55(a)	514230 XM_864101.2 XP_869194.1
rat (Rattus norvegicus)	L2hgdh¹	--	L-2-hydroxyglutarate dehydrogenase	83.95(n) 80.56(a)	314196 XM_234264.4 XP_234264.3
mouse (Mus musculus)	L2hgdh^{1, 5}	12⁵	L-2-hydroxyglutarate dehydrogenase^{1, 5}	84.38(n)¹ 82.51(a)¹	217666¹ NM_145443.1¹ NP_663418.1¹ AA822891⁵ AK139539⁵ (see all 9)

About this table Species with no ortholog for L2HGDH

ENSEMBL Gene Tree for L2HGDH

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/374 NCBI SNPs in L2HGDH are shown (see all 374 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 93)

AB	SNP ID	Valid	Chr 14 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs6572653^1,2	A,C	49782692(+)	`ttgttA/Gttttt`	1	--	ut3¹		0	--	--	--	--
	rs17122314^1,2	F,H	49781906(+)	`ACCATA/GCCACA`	1	--	ut3¹		7		NA EU EA WA	558
--	rs7157035^1,2	A,C	49782319(+)	`gcatgA/Gtggct`	1	--	ut3¹		0	--	--	--	--
--	rs7143186^1,2	C	49783429(+)	`AAAACG/TAAAGT`	1	--	ut3¹		0	--	--	--	--
--	rs6572652^1,2	C	49782602(+)	`aaaaaA/Taaata`	1	--	ut3¹		0	--	--	--	--
--	rs1964845^1,2	C	49782547(+)	`gatcgC/Taccat`	1	--	ut3¹		0	--	--	--	--
--	rs11849026^1,2	A	49780307(+)	`cccccC/Gacccc`	1	--	ut3¹ trp³		0	--	--	--	--
	rs2297995^1,2	A,C,F,H,O	49839467(+)	`CCAACA/GATGAC`	1	I/I	syn¹		11		EA EU WA NA	2316
	rs2355885^1,2	A,C,F,H,O	49802697(+)	`AAAGCT/CTGCCA`	1	--	int¹		7		EU EA WA NA	554
	rs743075^1,2	A,C,F,H,O	49784735(-)	`GATAGG/AATTTT`	1	--	int¹		15		NA EA MN EU WA	1327

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HapMap Linkage Disequilibrium images for L2HGDH (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 609584 disorders: 236792

UniProtKB/Swiss-Prot: L2HDH_HUMAN, Q9H9P8

Defects in L2HGDH are the cause of L-2-hydroxyglutaric aciduria (L2HGA) [MIM:236792].

L2HGA is a rare autosomal recessive disorder clinically characterized by mild psychomotor delay in

the first years of life, followed by progressive cerebellar ataxia, dysarthria and moderate to

severe mental retardation. Diagnosis is based on the presence of an excess of L-2-hydroxyglutaric

acid in urine, blood and cerebrospinal fluid

1 Novoseek disease relationship for L2HGDH gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
metabolic disorder	50.44	1	17603759 (1)

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Human Gene Mutation Database: L2HGDH

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/19 PubMed articles for L2HGDH gene (see all 19 ):

The gene mutated in L-2-hydroxyglutaric aciduria encodes L-2- hydroxyglutarate dehydrogenase. (PubMed id 16005139)^{1, 2, 3, 4} Rzem R.... Veiga-da-Cunha M. (2006)
Novel L2HGDH mutations in 21 patients with L-2-hydroxyglutaric aciduria of Portuguese origin. (PubMed id 16134148)^{1, 3, 4} Vilarinho L....Jakobs C. (2005)
L-2-hydroxyglutaric aciduria: identification of a mutant gene C14orf160, localized on chromosome 14q22.1. (PubMed id 15385440)^{1, 3, 4} Topcu M....Fischer J. (2004)
A gene encoding a putative FAD-dependent L-2-hydroxyglutarate dehydrogenase is mutated in L-2-hydroxyglutaric aciduria. (PubMed id 15548604)^{1, 3, 4} Rzem R....van Schaftingen E. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
L-2-hydroxyglutaric aciduria and brain tumors in children with mutations in the L2HGDH gene: neuroimaging findings. (PubMed id 18671189)^{1, 3} Haliloglu G....Topcu M. (2008)
L-2-hydroxyglutarate dehydrogenase: identification of a novel enzyme activity in rat and human liver. Implications for L-2-hydroxyglutaric acidemia. (PubMed id 8241290)^{1, 3} Jansen G.A. and Wanders R.J. (1993)
A successfully treated adult patient with L-2-hydroxyglutaric aciduria. (PubMed id 18362286)³ Samuraki M....Yamada M. (2008)
Novel insights into L-2-hydroxyglutaric aciduria: mass isotopomer studies reveal 2-oxoglutaric acid as the metabolic precursor of L-2-hydroxyglutaric acid. (PubMed id 17876720)³ Struys E.A....Jakobs C. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 79944	HGNC: 20499	AceView: C14orf160	Ensembl:ENSG00000087299	euGenes: HUgn79944
ECgene: L2HGDH	H-InvDB: L2HGDH

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
GeneReviews	http://www.genetests.org/query?gene=L2HGDH

Licensable Technologies for L2HGDH
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for L2HGDH:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for L2HGDH-related products

	Millipore Custom Antibody & Bulk Services
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	Predesigned and custom siRNAs for L2HGDH		Browse antibodies at Sigma-Aldrich
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	Lentivirus-delivered shRNAs for L2HGDH		Browse small molecules at Sigma-Aldrich
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L2HGDH Gene

protein-coding GIFtS: 50

Aliases &
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Summaries
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Genomic Location
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Proteins
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Protein Domains/
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Gene Function
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Pathways & Interactions
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Drugs & Compounds
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Transcripts
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Expression
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

L2HGDH Gene

protein-coding GIFtS: 50

Aliases & Descriptionsfor L2HGDH

Summariesfor L2HGDH

Genomic Locationfor L2HGDH

Proteinsfor L2HGDH

Protein Domains/Familiesfor L2HGDH

Gene Functionfor L2HGDH

Pathways & Interactionsfor L2HGDH

Drugs & Compoundsfor L2HGDH

Transcriptsfor L2HGDH

Expression for L2HGDH

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Disorders & Mutationsfor L2HGDH

Medical Newsfor L2HGDH

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Genome Databases showing L2HGDH

Other Databases showing L2HGDH

Specialized Databases showing L2HGDH

Licensable Technologiesfor L2HGDH

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for L2HGDH

Summaries
for L2HGDH

Genomic Location
for L2HGDH

Proteins
for L2HGDH

Protein Domains/
Families
for L2HGDH

Gene Function
for L2HGDH

Pathways & Interactions
for L2HGDH

Drugs & Compounds
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