KTN1 Gene
protein-coding GIFtS: 54
GCID: GC14P056046
|
|
kinectin 1 (kinesin receptor)
| |
Aliases
for KTN1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Kinectin 1 (Kinesin Receptor)1 2 | | CG-1 Antigen2 3 | | CG11 2 3 5 | | KNT2 | | KIAA00041 3 | | MU-RMS-40.192 | | Kinesin Receptor2 3 | | Kinectin1 |
Export aliases for KTN1 gene to outside databasesPrevious GC identifers: GC14P053370 GC14P049842 GC14P054037 GC14P055116 GC14P036232 |
Summaries
for KTN1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KTN1:
This gene encodes an integral membrane protein that is a member of the kinectin protein family. The encoded protein isprimarily localized to the endoplasmic reticulum membrane. This protein binds kinesin and may be involved inintracellular organelle motility. This protein also binds translation elongation factor-delta and may be involved inthe assembly of the elongation factor-1 complex. Alternate splicing results in multiple transcript variants of thisgene. (provided by RefSeq, Aug 2012)
UniProtKB/Swiss-Prot: KTN1_HUMAN, Q86UP2Function: Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesioncomplexes (IAC) upon integrin aggregation by fibronectin
Gene Wiki entry for KTN1
|
Genomic Views
for KTN1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KTN1 gene promoter:
SRF Max1 AML1a SRF (504 AA) CUTL1 Roaz MEF-2A aMEF-2 Pax-4a c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for KTN1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KTN1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q22.1 Ensembl cytogenetic band: 14q22.3 HGNC cytogenetic band: 14q22.1KTN1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14P056046: view genomic region
(about GC identifiers)
Start:
|
56,025,790 bp from pter |
End:
|
56,168,244 bp from pter |
Size:
|
142,455 bases |
Orientation:
|
plus strand |
|
Proteins
for KTN1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KTN1_HUMAN, Q86UP2 (See
protein sequence)Recommended Name: Kinectin Size: 1357 amino acids; 156275 Da
Subunit: Parallel homodimers formed between the membrane-bound and the cytosolic form, and also between 2 cytosolicforms (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Vesicle membraneprotein anchored to the endoplasmic reticulum
Sequence caution: Sequence=AAH50555.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-Asequence; Sequence=BAA02794.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q13999 Q14707 Q15387 Q17RZ5 Q86W57Alternative splicing: 3 isoforms: Q86UP2-1 Q86UP2-2 Q86UP2-3 Explore the universe of human proteins at neXtProt for KTN1: NX_Q86UP2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86UP2
KTN1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001257943.1 NP_004977.2 NP_001072989.1 NP_001072990.1
ENSEMBL proteins: ENSP00000451641 ENSP00000452459 ENSP00000451878 ENSP00000391964 ENSP00000378725 ENSP00000432149 ENSP00000378719 ENSP00000378722 ENSP00000452576 ENSP00000452073 ENSP00000452337 ENSP00000452205 ENSP00000452445 ENSP00000451698 ENSP00000451876 ENSP00000451139 ENSP00000394992 ENSP00000378720 ENSP00000388807
Human Recombinant Protein Products for KTN1:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
KTN1 for ontologies About GeneDecksing
KTN1 Antibody Products:
Assay Products for KTN1: |
Protein
Domains /
Families
for KTN1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KTN1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q86UP2ProtoNet protein and cluster: Q86UP2 1 Blocks protein family: IPB002017 Spectrin repeat
UniProtKB/Swiss-Prot: KTN1_HUMAN, Q86UP2Similarity: Belongs to the kinectin family |
Function
for KTN1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: KTN1_HUMAN, Q86UP2Function: Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesioncomplexes (IAC) upon integrin aggregation by fibronectin Genatlas biochemistry entry for KTN1:kinectin 1,156kDa,vesicle membrane protein of the endoplasmic reticulum,binding vesicles to kinesin and promotingvesicle motility,expressed in diverse tissues
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- | | GO:0019894 | kinesin binding |
IEA | -- |
KTN1 for ontologies About GeneDecksing
Phenotypes:
2 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Ktn1):
KTN1 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Ktn1tm1.2Kpf for KTN1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KTN1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KTN1 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): KTN1 (NM_004986) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KTN1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KTN1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KTN1 |
|
Pathways & Interactions
for KTN1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cytoskeletal Signaling | | | 2 | TNF-alpha/NF-kB Signaling Pathway | | | 3 | Actin Nucleation by ARP-WASP Complex | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for KTN1
1 
Cell Signaling Technology (CST) Pathway for KTN1
1  BioSystems Pathway for KTN1
KTN1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for KTN1
5/17 Interacting proteins for KTN1 (Q86UP22, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 17)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007018 | microtubule-based movement |
IEA | -- | | GO:0015031 | protein transport |
-- | -- |
KTN1 for ontologies About GeneDecksing
|
Drugs & Compounds
for KTN1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
KTN1 for compounds About GeneDecksing
 Browse Tocris compounds for KTN1
2 Novoseek chemical compound relationships for KTN1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| leucine |
14.4 |
1 |
9169133 (1) |
| tyrosine |
9.29 |
3 |
16848005 (1), 16540262 (1), 16912993 (1) |
Search CenterWatch for drugs/clinical trials and news about KTN1
|
Transcripts
for KTN1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KTN1 gene (5 alternative transcripts): NM_001271014.1 NM_004986.3 NM_182926.2 NM_001079521.1 NM_001079522.1 Unigene Cluster for KTN1: Kinectin 1 (kinesin receptor) Hs.509414 [show with all ESTs]Unigene Representative Sequence: NR_07312918/26 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 26): ENST00000557267 ENST00000554567 ENST00000555498 ENST00000438792 ENST00000395314(uc001xcc.3)
ENST00000459737(uc001xcb.3 uc001xcd.3 uc010trb.2) ENST00000395308
ENST00000395311 ENST00000553360 ENST00000554507 ENST00000554890 ENST00000555164
ENST00000554306 ENST00000554570 ENST00000553624 ENST00000555573(uc010trc.2)
ENST00000555172(uc001xcg.3) ENST00000334975
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KTN1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KTN1 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): KTN1 (NM_004986) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KTN1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KTN1 |
Additional cDNA sequence: AJ270687.1 AK300703.1 AK302797.1 AK308272.1 AK309840.1 AY264265.1 AY536375.1 BC050555.1 BC058736.1 BC066337.1 BC104648.1 BC112337.1 BC117132.1 BC143720.1 D13629.1 L25616.1 NR_073128.1 NR_073129.1 Z22551.1 24/48 DOTS entries (see all 48): DT.85104713 DT.95375978 DT.91786580 DT.101957505 DT.97850477 DT.95376001 DT.120792524 DT.120792661 DT.99988670 DT.75110805 DT.100038614 DT.100667517 DT.100679485 DT.100679490 DT.120792595 DT.100655189 DT.100679488 DT.120792656 DT.92457122 DT.95225282 DT.97798810 DT.100866936 DT.95375997 DT.449614 24/582 AceView cDNA sequences (see all 582): AI264136 CK820668 AI139271 AA307630 T27977 BX117645 AI718511 NM_182926 AI566708 AW589472 BQ233871 BG113577 BM470976 AA196575 BG565003 L25616 AA251780 CB136107 BX477074 CA390916 AL138316 BM983276 BU680731 AK125499
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for KTN1 (see all 12) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33 | ^ | 34 | ^ | 35a | · | 35b | · | 35c | ^ | 36a | · | 36b | ^ | 37 | ^ | 38 | ^ | 39a | · | 39b | ^ | 40 | ^ | 41 | ^ | 42 | ^ | 43a | · | 43b | ^ | 44a | · | 44b | ^ | 45a | · | 45b | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | - | | - | | | | - | | | | | | | | - | | | | | | | | | | | | - | | - | | | | | | - | | |
| SP2: | | | | | | | | | | | | | | | | | - | | - | | | | - | | - | | | | | | - | | | | | | | | | | - | | - | | - | | | | | | - | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | - | | - | | | | | | - | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | - | | - | | | | | | - | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | |
| ExUns: | 46 | ^ | 47 |
|---|
|
| SP1: | | | | | |
| SP2: | | | | | |
| SP3: | | | | | |
| SP4: | | | | | |
| SP5: | | | | |
ECgene alternative splicing isoforms for KTN1
|
Expression
for KTN1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KTN1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAATCTTTTA
About this image
See KTN1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KTN1
SOURCE GeneReport for Unigene cluster: Hs.509414
UniProtKB/Swiss-Prot: KTN1_HUMAN, Q86UP2Tissue specificity: High levels in peripheral blood lymphocytes, testis and ovary, lower levels in spleen, thymus,prostate, small intestine and colon
SABiosciences Custom PCR Arrays for KTN1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KTN1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KTN1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KTN1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KTN1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KTN1 |
Orthologs
for KTN1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for KTN1 gene from 8/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
KTN11 |
kinectin 1 (kinesin receptor) |
72.49(n)
68.02(a) |
|
396335 NM_205376.1 NP_990707.1 |
lizard
(Anolis carolinensis) |
Reptilia |
KTN16 |
-- |
65(a) |
1 ↔ 1 |
GL343459.1(142660-238129) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.24812 |
Xenopus laevis transcribed sequence with weak similarity more |
81.8(n) |
|
BJ052318.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
ktn12 |
kinectin 1 |
74.39(n) |
|
368207 BC044389.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
alt6 |
aluminum tubes |
15(a) |
1 → many |
3R(13499903-13508234) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT4G321906 |
Myosin heavy chain-related protein |
12(a) |
1 → many |
4(15544878-15547855) |
rice
(Oryza sativa) |
Liliopsida |
-- |
expressed protein |
12(a) |
1 → many |
2(4802877-4806456) |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
sbcC6 |
exonuclease, dsDNA, ATP-dependent |
8(a) |
1 → many |
Chromosome(411831-414977) |
ENSEMBL Gene Tree for KTN1 (if available)
TreeFam Gene Tree for KTN1 (if available) |
Paralogs
for KTN1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KTN1 gene
- RRBP12
1 SIMAP similar gene for KTN1 using alignment to 16 protein entries: KTN1_HUMAN (see all proteins):RRBP1
KTN1 for paralogs About GeneDecksing
|
Genomic Variants
for KTN1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KTN1 (56025790 - 56168244 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for KTN1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KTN1 |
|
Disorders
/ Diseases
for KTN1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KTN1 for disorders About GeneDecksing
OMIM gene information: 600381
OMIM disorders: --
14  diseases for KTN1: About MalaCardsconnective tissue disease giant cell tumor aplastic anemia papillary thyroid carcinoma
behcet's disease thyroid carcinoma hepatocellular carcinoma anemia
thyroiditis myopathy carcinoma melanoma
pancreatitis prostatitis
2 Novoseek disease relationships for KTN1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| autoimmune diseases |
17 |
1 |
12947009 (1) |
| hepatocellular carcinoma |
15.1 |
1 |
15060627 (1) |
Human Genome Epidemiology (HuGE) Navigator: KTN1 (3 documents)
Export disorders for KTN1 gene to outside databases
|
Publications
for KTN1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KTN1 gene, integrated from 9 sources (see all 82):
(articles sorted by number of sources associating them with KTN1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning and characterization of human kinectin. (PubMed id 7787243)1, 2, 9 Fuetterer A.... Kroenke M. (1995)
- Integrin clustering induces kinectin accumulation. (PubMed id 11973345)1, 2, 9 Tran H.... Yamada K.M. (2002)
- The CG-1 gene, a member of the kinectin and ES/130 family, maps to human chromosome band 14q22. (PubMed id 8575822)1, 2, 9 Print C.G.... Krissansen G.W. (1996)
- Assignment of the human kinectin gene (KTN1), encoding a kinesin-binding protein, to chromosome 14 band q22.1 by in situ hybridization. (PubMed id 9605849)1, 3, 9 Rao P.N....Sheetz M.P. (1997)
- Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry. (PubMed id 17370265)1, 2 Denis N.J.... Figeys D. (2007)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)1, 2 Heilig R.... Weissenbach J. (2003)
- Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. (PubMed id 7584026)1, 2 Nomura N.... Tabata S. (1994)
- Cloning of a gene encoding a human leukocyte protein characterised by extensive heptad repeats. (PubMed id 8039706)1, 2 Print C.G.... Krissansen G.W. (1994)
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External Searches for KTN1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing KTN1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing KTN1 gene
(According to HUGE)
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Specialized Databases showing KTN1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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About This Section
| Patent Information for KTN1 gene:
Search GeneIP for patents involving KTN1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for KTN1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KTN1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KTN1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KTN1 | | | OriGene Protein Over-expression Lysate for KTN1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KTN1 | | OriGene 3'-UTR Clone for KTN1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KTN1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KTN1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KTN1 | | OriGene Custom Protein Services for KTN1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KTN1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KTN1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KTN1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KTN1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KTN1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KTN1 |
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| | Antibodies & Assays for KTN1 |
| | | | Search Tocris compounds for KTN1 |
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 | | | KTN1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KTN1 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for KTN1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KTN1 |
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