Aliases for KTN1 Gene
External Ids for KTN1 Gene
Previous GeneCards Identifiers for KTN1 Gene
This gene encodes an integral membrane protein that is a member of the kinectin protein family. The encoded protein is primarily localized to the endoplasmic reticulum membrane. This protein binds kinesin and may be involved in intracellular organelle motility. This protein also binds translation elongation factor-delta and may be involved in the assembly of the elongation factor-1 complex. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Aug 2012]
GeneCards Summary for KTN1 Gene
KTN1 (Kinectin 1) is a Protein Coding gene. Among its related pathways are RHO GTPases activate KTN1 and Actin Nucleation by ARP-WASP Complex. GO annotations related to this gene include poly(A) RNA binding and kinesin binding. An important paralog of this gene is RRBP1.
UniProtKB/Swiss-Prot for KTN1 Gene
Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin.