KTI12 Gene
protein-coding GIFtS: 43
GCID: GC01M052497
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KTI12 homolog, chromatin associated (S. cerevisiae)
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Aliases
for KTI12 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| KTI12 Homolog, Chromatin Associated (S. Cerevisiae)1 2 | | TOT41 2 | | MGC204191 | | SBBI811 | | RP11-91A18.32 | | Protein KTI12 Homolog2 |
Export aliases for KTI12 gene to outside databasesPrevious GC identifers: GC01M052210 GC01M050615 |
Summaries
for KTI12 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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-- |
Genomic Views
for KTI12 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KTI12 gene promoter:
STAT5B Sox5 Elk-1 FOXD1 HNF-1A c-Ets-1 SRY FOXC1 HNF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for KTI12
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KTI12 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p32.3 Ensembl cytogenetic band: 1p32.3 HGNC cytogenetic band: 1p32.3KTI12 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M052497: view genomic region
(about GC identifiers)
Start:
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52,497,775 bp from pter |
End:
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52,499,488 bp from pter |
Size:
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1,714 bases |
Orientation:
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minus strand |
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Proteins
for KTI12 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KTI12_HUMAN, Q96EK9 (See
protein sequence)Recommended Name: Protein KTI12 homolog Size: 354 amino acids; 38616 DaExplore the universe of human proteins at neXtProt for KTI12: NX_Q96EK9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96EK9
KTI12 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_612426.1
ENSEMBL proteins: ENSP00000360676
Human Recombinant Protein Products:
KTI12 Antibody Products:
Assay Products for KTI12: |
Protein
Domains /
Families
for KTI12 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KTI12 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96EK9ProtoNet protein and cluster: Q96EK9 UniProtKB/Swiss-Prot: KTI12_HUMAN, Q96EK9Similarity: Belongs to the KTI12 family |
Function
for KTI12 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KTI12 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KTI12
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: KTI12 (NM_138417) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KTI12 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KTI12 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KTI12 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0005524 | ATP binding |
IEA | -- |
KTI12 for ontologies About GeneDecksing
|
Pathways & Interactions
for KTI12 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KTI12
STRING Interaction
Network Preview (showing 5 interactants - click image to see 20)
5/606 Interacting proteins for KTI12 (Q96EK92, 3 ENSP000003606764) via UniProtKB, MINT, STRING, and/or I2D (see all 606)About this table
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Drugs & Compounds
for KTI12 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KTI12
Search CenterWatch for drugs/clinical trials and news about KTI12
|
Transcripts
for KTI12 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KTI12 gene: NM_138417.2 1 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000371614(uc001ctj.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KTI12 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KTI12
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KTI12 (NM_138417) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KTI12 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KTI12 |
24/129 AceView cDNA sequences (see all 129): AI457495 BU186250 BQ941632 Z39178 CA487407 AI431906 BU790396 BU728775 BI909162 AI698247 AI039178 BG756607 NM_138417 F10771 F10255 BC012173 CB159211 BQ925211 AI686413 CA431422 BG054642 CR599183 BQ643498 AA056727
GeneLoc Exon Structure
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Expression
for KTI12 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KTI12 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTTCTGATC
About this image
See KTI12 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KTI12
SABiosciences Custom PCR Arrays for KTI12
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KTI12
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KTI12 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KTI12 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KTI12 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KTI12 |
Orthologs
for KTI12 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for KTI12 gene from 8/27 species (see all 27) About this table
ENSEMBL Gene Tree for KTI12 (if available)
TreeFam Gene Tree for KTI12 (if available) |
Paralogs
for KTI12 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for KTI12 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for KTI12
1 CNV: 4224 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KTI12 |
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Disorders
/ Diseases
for KTI12 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KTI12 for disorders About GeneDecksing
1  disease for KTI12: About MalaCardsostertagiasis
1 disease from the University of Copenhagen DISEASES database for KTI12:Ostertagiasis Export disorders for KTI12 gene to outside databases
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Publications
for KTI12 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KTI12 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with KTI12) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular analysis of KTI12/TOT4, a Saccharomyces cerevisiae gene required for Kluyveromyces lactis zymocin action. (PubMed id 11929532)1, 3, 9 Fichtner L....Schaffrath R. (2002)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for KTI12 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing KTI12 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing KTI12 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KTI12 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KTI12 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for KTI12 gene:
Search GeneIP for patents involving KTI12
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KTI12 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KTI12 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KTI12 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KTI12 | | | OriGene Protein Over-expression Lysate for KTI12 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KTI12 | | OriGene 3'-UTR Clone for KTI12 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KTI12 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KTI12 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for KTI12 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KTI12 | | OriGene Custom Protein Services for KTI12 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KTI12 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KTI12 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KTI12 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KTI12 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KTI12 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KTI12 |
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| | | | Search Tocris compounds for KTI12 |
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 | | | KTI12 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KTI12 |
|  |  |  | | | | ThermoFisher Antibodies for KTI12 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KTI12 |
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