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Aliases for KTI12 Gene

Aliases for KTI12 Gene

  • KTI12 Homolog, Chromatin Associated (S. Cerevisiae) 2 3
  • Protein KTI12 Homolog 3
  • SBBI81 3
  • TOT4 3

External Ids for KTI12 Gene

Previous GeneCards Identifiers for KTI12 Gene

  • GC01M052210
  • GC01M052497
  • GC01M050615

Summaries for KTI12 Gene

GeneCards Summary for KTI12 Gene

KTI12 (KTI12 Homolog, Chromatin Associated (S. Cerevisiae)) is a Protein Coding gene. Diseases associated with KTI12 include ostertagiasis.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KTI12 Gene

Genomics for KTI12 Gene

Regulatory Elements for KTI12 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for KTI12 Gene

52,032,103 bp from pter
52,033,816 bp from pter
1,714 bases
Minus strand

Genomic View for KTI12 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KTI12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KTI12 Gene

Proteins for KTI12 Gene

  • Protein details for KTI12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein KTI12 homolog
    Protein Accession:
    Secondary Accessions:

    Protein attributes for KTI12 Gene

    354 amino acids
    Molecular mass:
    38616 Da
    Quaternary structure:
    No Data Available

neXtProt entry for KTI12 Gene

Proteomics data for KTI12 Gene at MOPED

Post-translational modifications for KTI12 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KTI12 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for KTI12 Gene

Domains for KTI12 Gene

Protein Domains for KTI12 Gene


Suggested Antigen Peptide Sequences for KTI12 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the KTI12 family.
  • Belongs to the KTI12 family.
genes like me logo Genes that share domains with KTI12: view

No data available for Gene Families for KTI12 Gene

Function for KTI12 Gene

Gene Ontology (GO) - Molecular Function for KTI12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with KTI12: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for KTI12

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for KTI12 Gene

Localization for KTI12 Gene

Subcellular locations from

Jensen Localization Image for KTI12 Gene COMPARTMENTS Subcellular localization image for KTI12 gene
Compartment Confidence
extracellular 2
cytosol 1
mitochondrion 1
nucleus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KTI12 Gene

Pathways for KTI12 Gene

SuperPathways for KTI12 Gene

No Data Available

Gene Ontology (GO) - Biological Process for KTI12 Gene


No data available for Pathways by source for KTI12 Gene

Transcripts for KTI12 Gene

mRNA/cDNA for KTI12 Gene

(1) REFSEQ mRNAs :
(129) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for KTI12

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KTI12 Gene

No ASD Table

Relevant External Links for KTI12 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for KTI12 Gene

mRNA expression in normal human tissues for KTI12 Gene

Protein differential expression in normal tissues for KTI12 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (38.3) and Blymphocyte (8.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for KTI12 Gene

genes like me logo Genes that share expressions with KTI12: view

Expression partners for KTI12 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for KTI12 Gene

Orthologs for KTI12 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for KTI12 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia KTI12 35
  • 83.9 (n)
  • 84.75 (a)
(Canis familiaris)
Mammalia KTI12 35
  • 82.75 (n)
  • 83.33 (a)
KTI12 36
  • 82 (a)
(Mus musculus)
Mammalia Kti12 35
  • 77.68 (n)
  • 77.21 (a)
Kti12 16
Kti12 36
  • 76 (a)
(Pan troglodytes)
Mammalia KTI12 35
  • 99.34 (n)
  • 99.15 (a)
(Rattus norvegicus)
Mammalia Kti12 35
  • 78.48 (n)
  • 76.86 (a)
(Gallus gallus)
Aves TXNDC12 35
  • 66.81 (n)
  • 63.71 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia kti12 35
  • 60.02 (n)
  • 57.56 (a)
(Danio rerio)
Actinopterygii kti12 35
  • 57.14 (n)
  • 57.89 (a)
kti12 36
  • 56 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005190 35
  • 49.3 (n)
  • 37.64 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG3587 35
  • 48.43 (n)
  • 36.58 (a)
CG3587 36
  • 33 (a)
(Caenorhabditis elegans)
Secernentea CELE_Y57G11C.43 35
  • 46.01 (n)
  • 38.82 (a)
Y57G11C.43 36
  • 31 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ABL049C 35
  • 47.69 (n)
  • 36.76 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F02926g 35
  • 43.31 (n)
  • 35.43 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes KTI12 35
  • 42.86 (n)
  • 34.36 (a)
KTI12 36
  • 28 (a)
KTI12 38
thale cress
(Arabidopsis thaliana)
eudicotyledons DRL1 35
  • 42.08 (n)
  • 35.36 (a)
(Oryza sativa)
Liliopsida Os11g0312782 35
  • 45.27 (n)
  • 35.8 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU00178 35
  • 44.08 (n)
  • 33.43 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC30.02c 35
  • 44.23 (n)
  • 38.4 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5241 36
  • 39 (a)
Species with no ortholog for KTI12:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for KTI12 Gene

Gene Tree for KTI12 (if available)
Gene Tree for KTI12 (if available)

Paralogs for KTI12 Gene

No data available for Paralogs for KTI12 Gene

Variants for KTI12 Gene

Sequence variations from dbSNP and Humsavar for KTI12 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
VAR_032046 -

Structural Variations from Database of Genomic Variants (DGV) for KTI12 Gene

Variant ID Type Subtype PubMed ID
nsv829848 CNV Loss 17160897

Relevant External Links for KTI12 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KTI12 Gene

Disorders for KTI12 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for KTI12 Gene in MalaCards »

(1) Disease for KTI12 Gene

(1) University of Copenhagen DISEASES for KTI12 Gene

genes like me logo Genes that share disorders with KTI12: view

No data available for OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships , Genatlas and External Links for KTI12 Gene

Publications for KTI12 Gene

  1. Molecular analysis of KTI12/TOT4, a Saccharomyces cerevisiae gene required for Kluyveromyces lactis zymocin action. (PMID: 11929532) Fichtner L. … Schaffrath R. (Mol. Microbiol. 2002) 2 3 23
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for KTI12 Gene

Sources for KTI12 Gene

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