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Aliases for KTI12 Gene

Aliases for KTI12 Gene

  • KTI12 Homolog, Chromatin Associated (S. Cerevisiae) 2 3
  • Protein KTI12 Homolog 3
  • SBBI81 3
  • TOT4 3

External Ids for KTI12 Gene

Summaries for KTI12 Gene

GeneCards Summary for KTI12 Gene

KTI12 (KTI12 Homolog, Chromatin Associated (S. Cerevisiae)) is a Protein Coding gene. Diseases associated with KTI12 include ostertagiasis.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KTI12 Gene

Genomics for KTI12 Gene

Genomic Location for KTI12 Gene

Start:
52,032,103 bp from pter
End:
52,033,816 bp from pter
Size:
1,714 bases
Orientation:
Minus strand

Genomic View for KTI12 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KTI12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KTI12 Gene

Regulatory Elements for KTI12 Gene

Proteins for KTI12 Gene

  • Protein details for KTI12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96EK9-KTI12_HUMAN
    Recommended name:
    Protein KTI12 homolog
    Protein Accession:
    Q96EK9
    Secondary Accessions:

    Protein attributes for KTI12 Gene

    Size:
    354 amino acids
    Molecular mass:
    38616 Da
    Quaternary structure:
    No Data Available

neXtProt entry for KTI12 Gene

Proteomics data for KTI12 Gene at MOPED

Post-translational modifications for KTI12 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KTI12 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KTI12 Gene

Domains for KTI12 Gene

Protein Domains for KTI12 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

KTI12_HUMAN
Family:
  • Belongs to the KTI12 family.:
    • Q96EK9
genes like me logo Genes that share domains with KTI12: view

No data available for Gene Families for KTI12 Gene

Function for KTI12 Gene

Gene Ontology (GO) - Molecular Function for KTI12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with KTI12: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for KTI12 Gene

Localization for KTI12 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KTI12 Gene COMPARTMENTS Subcellular localization image for KTI12 gene
Compartment Confidence
extracellular 2
cytosol 1
mitochondrion 1
nucleus 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for KTI12 Gene

Pathways for KTI12 Gene

SuperPathways for KTI12 Gene

No Data Available

Gene Ontology (GO) - Biological Process for KTI12 Gene

None

No data available for Pathways by source for KTI12 Gene

Transcripts for KTI12 Gene

mRNA/cDNA for KTI12 Gene

(1) REFSEQ mRNAs :
(129) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for KTI12 Gene

No ASD Table

Relevant External Links for KTI12 Gene

GeneLoc Exon Structure for
KTI12
ECgene alternative splicing isoforms for
KTI12

Expression for KTI12 Gene

mRNA expression in normal human tissues for KTI12 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for KTI12 Gene

genes like me logo Genes that share expressions with KTI12: view

Orthologs for KTI12 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for KTI12 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KTI12 36
  • 99.34 (n)
  • 99.15 (a)
cow
(Bos Taurus)
Mammalia KTI12 36
  • 83.9 (n)
  • 84.75 (a)
dog
(Canis familiaris)
Mammalia KTI12 36
  • 82.75 (n)
  • 83.33 (a)
KTI12 37
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Kti12 36
  • 77.68 (n)
  • 77.21 (a)
Kti12 16
Kti12 37
  • 76 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Kti12 36
  • 78.48 (n)
  • 76.86 (a)
chicken
(Gallus gallus)
Aves TXNDC12 36
  • 66.81 (n)
  • 63.71 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia kti12 36
  • 60.02 (n)
  • 57.56 (a)
zebrafish
(Danio rerio)
Actinopterygii kti12 36
  • 57.14 (n)
  • 57.89 (a)
kti12 37
  • 56 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005190 36
  • 49.3 (n)
  • 37.64 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG3587 36
  • 48.43 (n)
  • 36.58 (a)
CG3587 37
  • 33 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea CELE_Y57G11C.43 36
  • 46.01 (n)
  • 38.82 (a)
Y57G11C.43 37
  • 31 (a)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ABL049C 36
  • 47.69 (n)
  • 36.76 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes KTI12 36
  • 42.86 (n)
  • 34.36 (a)
KTI12 37
  • 28 (a)
OneToOne
KTI12 39
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F02926g 36
  • 43.31 (n)
  • 35.43 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons DRL1 36
  • 42.08 (n)
  • 35.36 (a)
rice
(Oryza sativa)
Liliopsida Os11g0312782 36
  • 45.27 (n)
  • 35.8 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU00178 36
  • 44.08 (n)
  • 33.43 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC30.02c 36
  • 44.23 (n)
  • 38.4 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5241 37
  • 39 (a)
OneToOne
Species with no ortholog for KTI12:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for KTI12 Gene

ENSEMBL:
Gene Tree for KTI12 (if available)
TreeFam:
Gene Tree for KTI12 (if available)

Paralogs for KTI12 Gene

No data available for Paralogs for KTI12 Gene

Variants for KTI12 Gene

Sequence variations from dbSNP and Humsavar for KTI12 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
VAR_032046 -

Structural Variations from Database of Genomic Variants (DGV) for KTI12 Gene

Variant ID Type Subtype PubMed ID
nsv829848 CNV Loss 17160897

Relevant External Links for KTI12 Gene

HapMap Linkage Disequilibrium report
KTI12

Disorders for KTI12 Gene

(1) MalaCards Diseases for KTI12 Gene

Search for KTI12 Gene in MalaCards »

(1) University of Copenhagen DISEASES for KTI12 Gene

genes like me logo Genes that share disorders with KTI12: view

No data available for UniProtKB/Swiss-Prot for KTI12 Gene

Publications for KTI12 Gene

  1. Molecular analysis of KTI12/TOT4, a Saccharomyces cerevisiae gene required for Kluyveromyces lactis zymocin action. (PMID: 11929532) Fichtner L. … Schaffrath R. (Mol. Microbiol. 2002) 2 3 23
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for KTI12 Gene

Sources for KTI12 Gene

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