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Aliases for KRTAP5-11 Gene

Aliases for KRTAP5-11 Gene

  • Keratin Associated Protein 5-11 2 3
  • Ultrahigh Sulfur Keratin-Associated Protein 5.11 3 4
  • Keratin-Associated Protein 5.11 3 4
  • KRTAP5.11 3 4
  • Keratin-Associated Protein 5-11 3
  • Keratin Associated Protein 5-5 3
  • KRTAP5-5 3
  • KRTAP5-6 3
  • KAP5.11 4

External Ids for KRTAP5-11 Gene

Previous GeneCards Identifiers for KRTAP5-11 Gene

  • GC00U913948
  • GC11U900627
  • GC11M070971
  • GC11M071291
  • GC11M067586
  • GC11M071297

Summaries for KRTAP5-11 Gene

GeneCards Summary for KRTAP5-11 Gene

KRTAP5-11 (Keratin Associated Protein 5-11) is a Protein Coding gene.

UniProtKB/Swiss-Prot for KRTAP5-11 Gene

  • In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KRTAP5-11 Gene

Genomics for KRTAP5-11 Gene

Regulatory Elements for KRTAP5-11 Gene

Genomic Location for KRTAP5-11 Gene

Start:
71,579,714 bp from pter
End:
71,603,353 bp from pter
Size:
23,640 bases
Orientation:
Minus strand

Genomic View for KRTAP5-11 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KRTAP5-11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KRTAP5-11 Gene

Proteins for KRTAP5-11 Gene

  • Protein details for KRTAP5-11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6L8G4-KR511_HUMAN
    Recommended name:
    Keratin-associated protein 5-11
    Protein Accession:
    Q6L8G4
    Secondary Accessions:

    Protein attributes for KRTAP5-11 Gene

    Size:
    156 amino acids
    Molecular mass:
    14610 Da
    Quaternary structure:
    • Interacts with hair keratins

neXtProt entry for KRTAP5-11 Gene

Proteomics data for KRTAP5-11 Gene at MOPED

Post-translational modifications for KRTAP5-11 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KRTAP5-11 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KRTAP5-11 Gene

Domains for KRTAP5-11 Gene

Gene Families for KRTAP5-11 Gene

HGNC:
  • KRTAP :Keratin associated proteins

Protein Domains for KRTAP5-11 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for KRTAP5-11 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6L8G4

UniProtKB/Swiss-Prot:

KR511_HUMAN :
  • Q6L8G4
Family:
  • Belongs to the KRTAP type 5 family.
genes like me logo Genes that share domains with KRTAP5-11: view

Function for KRTAP5-11 Gene

Molecular function for KRTAP5-11 Gene

UniProtKB/Swiss-Prot Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

Animal Model Products

CRISPR Products

miRNA Products

  • QIAGEN qRT-PCR Assays for microRNAs that regulate KRTAP5-11
    • Block miRNA regulation of KRTAP5-11 using miScript Target Protectors

    Inhibitory RNA Products

    • Predesigned siRNA for gene silencing in human,mouse,rat for KRTAP5-11

    In Situ Assay Products

    Flow Cytometry Products

    No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for KRTAP5-11 Gene

    Localization for KRTAP5-11 Gene

    Subcellular locations from

    COMPARTMENTS
    Jensen Localization Image for KRTAP5-11 Gene COMPARTMENTS Subcellular localization image for KRTAP5-11 gene
    Compartment Confidence
    extracellular 3
    cytoskeleton 2
    cytosol 1
    nucleus 1

    Gene Ontology (GO) - Cellular Components for KRTAP5-11 Gene

    GO ID Qualified GO term Evidence PubMed IDs
    GO:0045095 keratin filament IEA --
    genes like me logo Genes that share ontologies with KRTAP5-11: view

    No data available for Subcellular locations from UniProtKB/Swiss-Prot for KRTAP5-11 Gene

    Pathways for KRTAP5-11 Gene

    SuperPathways for KRTAP5-11 Gene

    No Data Available

    Interacting Proteins for KRTAP5-11 Gene

    Gene Ontology (GO) - Biological Process for KRTAP5-11 Gene

    None

    No data available for Pathways by source for KRTAP5-11 Gene

    Transcripts for KRTAP5-11 Gene

    mRNA/cDNA for KRTAP5-11 Gene

    (8) Selected AceView cDNA sequences:
    (4) Additional mRNA sequences :
    (1) REFSEQ mRNAs :
    (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

    Unigene Clusters for KRTAP5-11 Gene

    Keratin associated protein 5-11:
    Representative Sequences:

    CRISPR Products

    miRNA Products

    • QIAGEN qRT-PCR Assays for microRNAs that regulate KRTAP5-11
      • Block miRNA regulation of KRTAP5-11 using miScript Target Protectors

      Inhibitory RNA Products

      • Predesigned siRNA for gene silencing in human,mouse,rat for KRTAP5-11

      Primer Products

      • OriGene qSTAR qPCR primer pairs in human,mouse,rat for KRTAP5-11
      • QuantiTect SYBR Green Assays in human,mouse,rat
      • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
      • QuantiFast Probe-based Assays in human,mouse,rat

      Flow Cytometry Products

      Alternative Splicing Database (ASD) splice patterns (SP) for KRTAP5-11 Gene

      No ASD Table

      Relevant External Links for KRTAP5-11 Gene

      GeneLoc Exon Structure for
      KRTAP5-11
      ECgene alternative splicing isoforms for
      KRTAP5-11

      Expression for KRTAP5-11 Gene

      mRNA expression in normal human tissues for KRTAP5-11 Gene

      mRNA expression in normal human tissues for KRTAP5-11 Gene

      SOURCE GeneReport for Unigene cluster for KRTAP5-11 Gene Hs.679617

      mRNA Expression by UniProt/SwissProt for KRTAP5-11 Gene

      Q6L8G4-KR511_HUMAN
      Tissue specificity: Restricted to hair root, not detected in any other tissues.
      genes like me logo Genes that share expressions with KRTAP5-11: view

      In Situ Assay Products

      No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Protein expression for KRTAP5-11 Gene

      Orthologs for KRTAP5-11 Gene

      Evolution for KRTAP5-11 Gene

      ENSEMBL:
      Gene Tree for KRTAP5-11 (if available)
      TreeFam:
      Gene Tree for KRTAP5-11 (if available)

      No data available for Orthologs for KRTAP5-11 Gene

      Paralogs for KRTAP5-11 Gene

      No data available for Paralogs for KRTAP5-11 Gene

      Variants for KRTAP5-11 Gene

      Sequence variations from dbSNP and Humsavar for KRTAP5-11 Gene

      SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
      rs5021465 -- 71,582,018(+) GAGAA(A/G)CTGGT utr-variant-3-prime
      rs7105733 -- 71,584,858(+) GGGGC(G/T)AGGCG upstream-variant-2KB
      rs7106630 -- 71,584,847(+) CCCAT(C/T)GCAGG upstream-variant-2KB
      rs10751118 -- 71,583,780(+) cccca(C/G)caatg upstream-variant-2KB
      rs10751119 -- 71,583,949(+) CTCCT(A/T)CCTTA upstream-variant-2KB

      Structural Variations from Database of Genomic Variants (DGV) for KRTAP5-11 Gene

      Variant ID Type Subtype PubMed ID
      nsv825988 CNV Loss 20364138

      Relevant External Links for KRTAP5-11 Gene

      HapMap Linkage Disequilibrium report
      KRTAP5-11

      No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KRTAP5-11 Gene

      Disorders for KRTAP5-11 Gene

      No disorders were found for KRTAP5-11 Gene.

      No data available for UniProtKB/Swiss-Prot for KRTAP5-11 Gene

      Publications for KRTAP5-11 Gene

      1. Identification of two novel clusters of ultrahigh-sulfur keratin- associated protein genes on human chromosome 11. (PMID: 15144888) Yahagi S. … Shimizu N. (Biochem. Biophys. Res. Commun. 2004) 2 3 4
      2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

      Products for KRTAP5-11 Gene

      Sources for KRTAP5-11 Gene

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