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Aliases for KRTAP5-11 Gene

Aliases for KRTAP5-11 Gene

  • Keratin Associated Protein 5-11 2 3
  • Ultrahigh Sulfur Keratin-Associated Protein 5.11 3 4
  • Keratin-Associated Protein 5.11 3 4
  • KRTAP5.11 3 4
  • Keratin-Associated Protein 5-11 3
  • Keratin Associated Protein 5-5 3
  • KRTAP5-5 3
  • KRTAP5-6 3
  • KAP5.11 4

External Ids for KRTAP5-11 Gene

Summaries for KRTAP5-11 Gene

GeneCards Summary for KRTAP5-11 Gene

KRTAP5-11 (Keratin Associated Protein 5-11) is a Protein Coding gene.

UniProtKB/Swiss-Prot for KRTAP5-11 Gene

  • In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KRTAP5-11 Gene

Genomics for KRTAP5-11 Gene

Genomic Location for KRTAP5-11 Gene

Start:
71,579,714 bp from pter
End:
71,603,353 bp from pter
Size:
23,640 bases
Orientation:
Minus strand

Genomic View for KRTAP5-11 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KRTAP5-11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KRTAP5-11 Gene

Regulatory Elements for KRTAP5-11 Gene

Proteins for KRTAP5-11 Gene

  • Protein details for KRTAP5-11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6L8G4-KR511_HUMAN
    Recommended name:
    Keratin-associated protein 5-11
    Protein Accession:
    Q6L8G4
    Secondary Accessions:

    Protein attributes for KRTAP5-11 Gene

    Size:
    156 amino acids
    Molecular mass:
    14610 Da
    Quaternary structure:
    • Interacts with hair keratins

neXtProt entry for KRTAP5-11 Gene

Proteomics data for KRTAP5-11 Gene at MOPED

Post-translational modifications for KRTAP5-11 Gene

No Post-translational modifications

Other Protein References for KRTAP5-11 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KRTAP5-11 Gene

Domains for KRTAP5-11 Gene

Gene Families for KRTAP5-11 Gene

HGNC:
  • KRTAP :Keratin associated proteins

Protein Domains for KRTAP5-11 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

KR511_HUMAN
Family:
  • Belongs to the KRTAP type 5 family.:
    • Q6L8G4
genes like me logo Genes that share domains with KRTAP5-11: view

Function for KRTAP5-11 Gene

Molecular function for KRTAP5-11 Gene

UniProtKB/Swiss-Prot Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for KRTAP5-11 Gene

Localization for KRTAP5-11 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KRTAP5-11 Gene COMPARTMENTS Subcellular localization image for KRTAP5-11 gene
Compartment Confidence
extracellular 3
cytoskeleton 2
cytosol 1
nucleus 1

Gene Ontology (GO) - Cellular Components for KRTAP5-11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0045095 keratin filament IEA --
genes like me logo Genes that share ontologies with KRTAP5-11: view

Pathways for KRTAP5-11 Gene

SuperPathways for KRTAP5-11 Gene

No Data Available

Interacting Proteins for KRTAP5-11 Gene

Gene Ontology (GO) - Biological Process for KRTAP5-11 Gene

None

No data available for Pathways by source for KRTAP5-11 Gene

Transcripts for KRTAP5-11 Gene

mRNA/cDNA for KRTAP5-11 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(8) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for KRTAP5-11 Gene

Keratin associated protein 5-11:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KRTAP5-11 Gene

No ASD Table

Relevant External Links for KRTAP5-11 Gene

GeneLoc Exon Structure for
KRTAP5-11
ECgene alternative splicing isoforms for
KRTAP5-11

Expression for KRTAP5-11 Gene

mRNA expression in normal human tissues for KRTAP5-11 Gene

mRNA expression in normal human tissues for KRTAP5-11 Gene

SOURCE GeneReport for Unigene cluster for KRTAP5-11 Gene Hs.679617

mRNA Expression by UniProt/SwissProt for KRTAP5-11 Gene

Q6L8G4-KR511_HUMAN
Tissue specificity: Restricted to hair root, not detected in any other tissues.
genes like me logo Genes that share expressions with KRTAP5-11: view

Orthologs for KRTAP5-11 Gene

Evolution for KRTAP5-11 Gene

ENSEMBL:
Gene Tree for KRTAP5-11 (if available)
TreeFam:
Gene Tree for KRTAP5-11 (if available)

No data available for Orthologs for KRTAP5-11 Gene

Paralogs for KRTAP5-11 Gene

No data available for Paralogs for KRTAP5-11 Gene

Variants for KRTAP5-11 Gene

Sequence variations from dbSNP and Humsavar for KRTAP5-11 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs5021465 -- 71,582,018(+) GAGAA(A/G)CTGGT utr-variant-3-prime
rs7105733 -- 71,584,858(+) GGGGC(G/T)AGGCG upstream-variant-2KB
rs7106630 -- 71,584,847(+) CCCAT(C/T)GCAGG upstream-variant-2KB
rs10751118 -- 71,583,780(+) cccca(C/G)caatg upstream-variant-2KB
rs10751119 -- 71,583,949(+) CTCCT(A/T)CCTTA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for KRTAP5-11 Gene

Variant ID Type Subtype PubMed ID
nsv825988 CNV Loss 20364138

Relevant External Links for KRTAP5-11 Gene

HapMap Linkage Disequilibrium report
KRTAP5-11

Disorders for KRTAP5-11 Gene

No disorders were found for KRTAP5-11 Gene.

No data available for UniProtKB/Swiss-Prot for KRTAP5-11 Gene

Publications for KRTAP5-11 Gene

  1. Identification of two novel clusters of ultrahigh-sulfur keratin- associated protein genes on human chromosome 11. (PMID: 15144888) Yahagi S. … Shimizu N. (Biochem. Biophys. Res. Commun. 2004) 2 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for KRTAP5-11 Gene

Sources for KRTAP5-11 Gene

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