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Aliases for KRTAP19-6 Gene

Aliases for KRTAP19-6 Gene

  • Keratin Associated Protein 19-6 2 3
  • KAP19.6 3 4
  • Keratin-Associated Protein 19-6 3

External Ids for KRTAP19-6 Gene

Summaries for KRTAP19-6 Gene

GeneCards Summary for KRTAP19-6 Gene

KRTAP19-6 (Keratin Associated Protein 19-6) is a Protein Coding gene.

UniProtKB/Swiss-Prot for KRTAP19-6 Gene

  • In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KRTAP19-6 Gene

Genomics for KRTAP19-6 Gene

Genomic Location for KRTAP19-6 Gene

Start:
30,541,535 bp from pter
End:
30,541,864 bp from pter
Size:
330 bases
Orientation:
Minus strand

Genomic View for KRTAP19-6 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KRTAP19-6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KRTAP19-6 Gene

Regulatory Elements for KRTAP19-6 Gene

Proteins for KRTAP19-6 Gene

  • Protein details for KRTAP19-6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q3LI70-KR196_HUMAN
    Recommended name:
    Keratin-associated protein 19-6
    Protein Accession:
    Q3LI70
    Secondary Accessions:
    • Q3LI71

    Protein attributes for KRTAP19-6 Gene

    Size:
    58 amino acids
    Molecular mass:
    6267 Da
    Quaternary structure:
    • Interacts with hair keratins.
    SequenceCaution:
    • Sequence=BAE46363.1; Type=Frameshift; Positions=59; Evidence={ECO:0000305};

neXtProt entry for KRTAP19-6 Gene

Proteomics data for KRTAP19-6 Gene at MOPED

Post-translational modifications for KRTAP19-6 Gene

No Post-translational modifications

Other Protein References for KRTAP19-6 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KRTAP19-6 Gene

Domains for KRTAP19-6 Gene

Gene Families for KRTAP19-6 Gene

HGNC:
  • KRTAP :Keratin associated proteins

Protein Domains for KRTAP19-6 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for KRTAP19-6 Gene

Graphical View of Domain Structure for InterPro Entry

Q3LI70

UniProtKB/Swiss-Prot:

KR196_HUMAN
Family:
  • Belongs to the KRTAP type 19 family.:
    • Q3LI70
genes like me logo Genes that share domains with KRTAP19-6: view

Function for KRTAP19-6 Gene

Molecular function for KRTAP19-6 Gene

UniProtKB/Swiss-Prot Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

Phenotypes for KRTAP19-6 Gene

GenomeRNAi human phenotypes for KRTAP19-6:
genes like me logo Genes that share phenotypes with KRTAP19-6: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for KRTAP19-6 Gene

Localization for KRTAP19-6 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KRTAP19-6 Gene COMPARTMENTS Subcellular localization image for KRTAP19-6 gene
Compartment Confidence
cytoskeleton 3
extracellular 3

Gene Ontology (GO) - Cellular Components for KRTAP19-6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005882 intermediate filament IEA --
genes like me logo Genes that share ontologies with KRTAP19-6: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for KRTAP19-6 Gene

Pathways for KRTAP19-6 Gene

SuperPathways for KRTAP19-6 Gene

No Data Available

Interacting Proteins for KRTAP19-6 Gene

Gene Ontology (GO) - Biological Process for KRTAP19-6 Gene

None

No data available for Pathways by source for KRTAP19-6 Gene

Transcripts for KRTAP19-6 Gene

mRNA/cDNA for KRTAP19-6 Gene

(2) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for KRTAP19-6 Gene

No ASD Table

Relevant External Links for KRTAP19-6 Gene

GeneLoc Exon Structure for
KRTAP19-6
ECgene alternative splicing isoforms for
KRTAP19-6

Expression for KRTAP19-6 Gene

mRNA expression in normal human tissues for KRTAP19-6 Gene

SOURCE GeneReport for Unigene cluster for KRTAP19-6 Gene Hs.553695

genes like me logo Genes that share expressions with KRTAP19-6: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for KRTAP19-6 Gene

Orthologs for KRTAP19-6 Gene

Evolution for KRTAP19-6 Gene

ENSEMBL:
Gene Tree for KRTAP19-6 (if available)
TreeFam:
Gene Tree for KRTAP19-6 (if available)

No data available for Orthologs for KRTAP19-6 Gene

Paralogs for KRTAP19-6 Gene

No data available for Paralogs for KRTAP19-6 Gene

Variants for KRTAP19-6 Gene

Sequence variations from dbSNP and Humsavar for KRTAP19-6 Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type MAF
rs2832941 -- 30,541,347(+) TTGAA(A/G)TCTCA downstream-variant-500B
rs5843453 -- 30,541,663(+) TAGTA(-/G)AATCC frameshift-variant, reference
rs7278702 -- 30,543,606(+) tttcc(C/G/T)tacag upstream-variant-2KB
rs35229100 -- 30,543,594(+) TTAGA(-/T)TTTTT upstream-variant-2KB
rs35756424 -- 30,541,293(+) AAAAC(-/AT)TGTTG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for KRTAP19-6 Gene

Variant ID Type Subtype PubMed ID
nsv913677 CNV Loss 21882294

Relevant External Links for KRTAP19-6 Gene

HapMap Linkage Disequilibrium report
KRTAP19-6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KRTAP19-6 Gene

Disorders for KRTAP19-6 Gene

No disorders were found for KRTAP19-6 Gene.

No data available for UniProtKB/Swiss-Prot for KRTAP19-6 Gene

Publications for KRTAP19-6 Gene

  1. Characterization of a first domain of human high glycine-tyrosine and high sulfur keratin-associated protein (KAP) genes on chromosome 21q22.1. (PMID: 12359730) Rogers M.A. … Schweizer J. (J. Biol. Chem. 2002) 2 3
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. The DNA sequence of human chromosome 21. (PMID: 10830953) Hattori M. … Yaspo M.-L. (Nature 2000) 4

Products for KRTAP19-6 Gene

Sources for KRTAP19-6 Gene

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