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Aliases for KRTAP16-1 Gene

Aliases for KRTAP16-1 Gene

  • Keratin Associated Protein 16-1 2 3 5
  • KAP16.1 3 4
  • Putative Keratin-Associated Protein 10-Like ENSP00000375147 3

External Ids for KRTAP16-1 Gene

Previous GeneCards Identifiers for KRTAP16-1 Gene

  • GC17U900020
  • GC17M039372
  • GC17M039837
  • GC17M036719
  • GC17M039463

Summaries for KRTAP16-1 Gene

GeneCards Summary for KRTAP16-1 Gene

KRTAP16-1 (Keratin Associated Protein 16-1) is a Protein Coding gene. An important paralog of this gene is KRTAP10-2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KRTAP16-1 Gene

Genomics for KRTAP16-1 Gene

Regulatory Elements for KRTAP16-1 Gene

Promoters for KRTAP16-1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around KRTAP16-1 on UCSC Golden Path with GeneCards custom track

Genomic Location for KRTAP16-1 Gene

Chromosome:
17
Start:
41,307,700 bp from pter
End:
41,309,253 bp from pter
Size:
1,554 bases
Orientation:
Minus strand

Genomic View for KRTAP16-1 Gene

Genes around KRTAP16-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KRTAP16-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KRTAP16-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KRTAP16-1 Gene

Proteins for KRTAP16-1 Gene

  • Protein details for KRTAP16-1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MUX0-KR161_HUMAN
    Recommended name:
    Keratin-associated protein 16-1
    Protein Accession:
    A8MUX0

    Protein attributes for KRTAP16-1 Gene

    Size:
    517 amino acids
    Molecular mass:
    53912 Da
    Quaternary structure:
    No Data Available

neXtProt entry for KRTAP16-1 Gene

Proteomics data for KRTAP16-1 Gene at MOPED

Post-translational modifications for KRTAP16-1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KRTAP16-1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KRTAP16-1 Gene

Domains & Families for KRTAP16-1 Gene

Gene Families for KRTAP16-1 Gene

Protein Domains for KRTAP16-1 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

A8MUX0

UniProtKB/Swiss-Prot:

KR161_HUMAN :
  • Belongs to the KRTAP type 16 family.
Family:
  • Belongs to the KRTAP type 16 family.
genes like me logo Genes that share domains with KRTAP16-1: view

No data available for Suggested Antigen Peptide Sequences for KRTAP16-1 Gene

Function for KRTAP16-1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for KRTAP16-1 Gene

Localization for KRTAP16-1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KRTAP16-1 Gene COMPARTMENTS Subcellular localization image for KRTAP16-1 gene
Compartment Confidence
cytoskeleton 3
cytosol 2
mitochondrion 2
extracellular 1
nucleus 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KRTAP16-1 Gene

Pathways & Interactions for KRTAP16-1 Gene

SuperPathways for KRTAP16-1 Gene

No Data Available

Interacting Proteins for KRTAP16-1 Gene

Gene Ontology (GO) - Biological Process for KRTAP16-1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KRTAP16-1 Gene

Drugs & Compounds for KRTAP16-1 Gene

No Compound Related Data Available

Transcripts for KRTAP16-1 Gene

mRNA/cDNA for KRTAP16-1 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for KRTAP16-1 Gene

Keratin associated protein 16-1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KRTAP16-1 Gene

No ASD Table

Relevant External Links for KRTAP16-1 Gene

GeneLoc Exon Structure for
KRTAP16-1
ECgene alternative splicing isoforms for
KRTAP16-1

Expression for KRTAP16-1 Gene

mRNA expression in normal human tissues for KRTAP16-1 Gene

mRNA differential expression in normal tissues according to GTEx for KRTAP16-1 Gene

This gene is overexpressed in Skin - Not Sun Exposed (Suprapubic) (x45.7) and Skin - Sun Exposed (Lower leg) (x5.7).

SOURCE GeneReport for Unigene cluster for KRTAP16-1 Gene Hs.721600

genes like me logo Genes that share expression patterns with KRTAP16-1: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for KRTAP16-1 Gene

Orthologs for KRTAP16-1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for KRTAP16-1 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia KRTAP16-1 35
  • 83.14 (n)
  • 78.82 (a)
KRTAP16-1 36
  • 62 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm11570 35
  • 80.11 (n)
  • 76.05 (a)
Krtap16-1 16
Krtap16-1 36
  • 65 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia LOC468256 35
  • 99.03 (n)
  • 97.68 (a)
KRTAP16-1 36
  • 37 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Krtap16-1 35
  • 80.3 (n)
  • 76.87 (a)
oppossum
(Monodelphis domestica)
Mammalia KRTAP16-1 36
  • 32 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KRTAP16-1 36
  • 32 (a)
OneToOne
Species with no ortholog for KRTAP16-1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for KRTAP16-1 Gene

ENSEMBL:
Gene Tree for KRTAP16-1 (if available)
TreeFam:
Gene Tree for KRTAP16-1 (if available)

Paralogs for KRTAP16-1 Gene

(8) SIMAP similar genes for KRTAP16-1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for KRTAP16-1 Gene

genes like me logo Genes that share paralogs with KRTAP16-1: view

Variants for KRTAP16-1 Gene

Sequence variations from dbSNP and Humsavar for KRTAP16-1 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs2074284 -- 41,308,484(-) GCCAA(C/G)TTGCT reference, missense
rs2074285 -- 41,308,235(-) CTGTC(C/G)TTCTG reference, missense
rs2074286 -- 41,307,794(-) AGAGG(C/G)TCCCT reference, missense
rs2074287 -- 41,307,567(-) CTTAC(A/C)CCTCA downstream-variant-500B
rs2074288 -- 41,307,478(-) TCTTG(G/T)CTTCT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for KRTAP16-1 Gene

Variant ID Type Subtype PubMed ID
dgv961e1 CNV Complex 17122850

Variation tolerance for KRTAP16-1 Gene

Gene Damage Index Score: 13.34; 95.36% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KRTAP16-1 Gene

HapMap Linkage Disequilibrium report
KRTAP16-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KRTAP16-1 Gene

Disorders for KRTAP16-1 Gene

Relevant External Links for KRTAP16-1

Genetic Association Database (GAD)
KRTAP16-1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KRTAP16-1

No disorders were found for KRTAP16-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KRTAP16-1 Gene

Publications for KRTAP16-1 Gene

  1. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 3 4 67
  2. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3
  3. Characterization of a cluster of human high/ultrahigh sulfur keratin- associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21. (PMID: 11279113) Rogers M.A. … Schweizer J. (J. Biol. Chem. 2001) 3
  4. The DNA sequence of human chromosome 21. (PMID: 10830953) Hattori M. … Yaspo M.-L. (Nature 2000) 3

Products for KRTAP16-1 Gene

Sources for KRTAP16-1 Gene

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