Aliases for KRTAP10-5 Gene
External Ids for KRTAP10-5 Gene
Previous HGNC Symbols for KRTAP10-5 Gene
Previous GeneCards Identifiers for KRTAP10-5 Gene
This is an intronless gene located in a cluster of related genes on the q arm of chromosome 21. The proteins encoded by these genes form disulfide bonds with cysteine residues in hair keratins, thereby contributing to the structure and stability of hair fibers. [provided by RefSeq, Apr 2014]
GeneCards Summary for KRTAP10-5 Gene
KRTAP10-5 (Keratin Associated Protein 10-5) is a Protein Coding gene. GO annotations related to this gene include identical protein binding. An important paralog of this gene is KRTAP10-2.
UniProtKB/Swiss-Prot for KRTAP10-5 Gene
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.