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KRT86 Gene

protein-coding   GIFtS: 49
GCID: GC12P052643

Keratin 86

(Previous names: keratin, hair, basic, 6 (monilethrix))
(Previous symbol: KRTHB6)
  See KRT86-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Keratin 861 2     Hb12
KRTHB61 2 3 5     KRTHB12
Keratin, Hair, Basic, 6 (Monilethrix)1 2     MNX2
Hair Keratin K2.112 3     hHb62
Type II Hair Keratin Hb62 3     Hard Keratin, Type II, 62
Type-II Keratin Kb262 3     Keratin Protein HB62
K862 3     Keratin, Type II Cuticular Hb62
HB62 5     keratin-862
Hard Keratin Type II 61     Keratin-863

External Ids:    HGNC: 64631   Entrez Gene: 38922   Ensembl: ENSG000001704427   OMIM: 6019285   UniProtKB: O437903   

Export aliases for KRT86 gene to outside databases

Previous GC identifers: GC12P050982 GC12P052695 GC12P049730 GC12P052668


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for KRT86 Gene:
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic
protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are
clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure
similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related
subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair
keratin, as well as KRTHB1 and KRTHB3, is found primarily in the hair cortex. Mutations in this gene and KRTHB1
have been observed in patients with a rare dominant hair disease, monilethrix. (provided by RefSeq, Jul 2008)

GeneCards Summary for KRT86 Gene:
KRT86 (keratin 86) is a protein-coding gene. Diseases associated with KRT86 include monilethrix, and hair disease. GO annotations related to this gene include structural molecule activity. An important paralog of this gene is KRT74.

Gene Wiki entry for KRT86 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KRT86 gene promoter:
         AhR   c-Fos   HEN1   AP-1   HSF1short   HSF1 (long)   c-Jun   Arnt   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKRT86 promoter sequence
   Search Chromatin IP Primers for KRT86

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KRT86


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13   Ensembl cytogenetic band:  12q13.13   HGNC cytogenetic band: 12q13

KRT86 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KRT86 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P052643:  view genomic region     (about GC identifiers)

Start:
52,643,084 bp from pter      End:
52,702,947 bp from pter
Size:
59,864 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: KRT86_HUMAN, O43790 (See protein sequence)
Recommended Name: Keratin, type II cuticular Hb6  
Size: 486 amino acids; 53501 Da
Subunit: Heterotetramer of two type I and two type II keratins
Miscellaneous: There are two types of hair/microfibrillar keratin, I (acidic) and II (neutral to basic)
Secondary accessions: P78387

Explore the universe of human proteins at neXtProt for KRT86: NX_O43790

Explore proteomics data for KRT86 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KRT86 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_002275.1  
    ENSEMBL proteins: 
     ENSP00000452237   ENSP00000444533   ENSP00000443169   ENSP00000293525  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    IFF2: Intermediate filaments type II, keratins (basic)

    3 InterPro protein domains:
     IPR018039 Intermediate_filament_CS
     IPR001664 IF
     IPR003054 Keratin_II

    Graphical View of Domain Structure for InterPro Entry O43790

    ProtoNet protein and cluster: O43790

    2 Blocks protein domains:
    IPB001664 Intermediate filament protein
    IPB003054 Type II keratin signature


    UniProtKB/Swiss-Prot: KRT86_HUMAN, O43790
    Similarity: Belongs to the intermediate filament family


    Find genes that share domains with KRT86           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005198structural molecule activity IEA--
         
    Find genes that share ontologies with KRT86           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for KRT86:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KRT86
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    1 qRT-PCR Assays for microRNA that regulate KRT86:
    hsa-miR-4261
    SwitchGear 3'UTR luciferase reporter plasmidKRT86 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol3
    mitochondrion2
    nucleus1
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA--
    GO:0005882intermediate filament ----
    GO:0045095keratin filament IEA--

    Find genes that share ontologies with KRT86           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KRT86
    Interactions:

        Search GeneGlobe Interaction Network for KRT86

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for KRT86 (ENSP000002935254) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    USP15ENSP000002581234STRING: ENSP00000258123
    CALM1ENSP000003494674STRING: ENSP00000349467
    KXD1ENSP000002223074STRING: ENSP00000222307
    KRT15ENSP000002540434STRING: ENSP00000254043
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007010cytoskeleton organization ----

    Find genes that share ontologies with KRT86           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KRT86

    2 Novoseek inferred chemical compound relationships for KRT86 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    lysine 30.9 1 9804356 (1)
    glutamate 12.4 1 9804356 (1)



    Find genes that share compounds with KRT86           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for KRT86 gene: 
    NM_002284.3  

    Unigene Cluster for KRT86:

    Keratin 86
    Hs.278658  [show with all ESTs]
    Unigene Representative Sequence: NM_002284
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000553310 ENST00000423955 ENST00000544024 ENST00000293525(uc010snq.2 uc009zmg.3 uc001sad.3)

    miRNA
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    1 qRT-PCR Assays for microRNA that regulate KRT86:
    hsa-miR-4261
    SwitchGear 3'UTR luciferase reporter plasmidKRT86 3' UTR sequence
    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat KRT86

    Additional mRNA sequence: 

    AK292237.1 AK297794.1 BC069585.1 X99142.1 XR_111293.1 

    4 DOTS entries:

    DT.95069074  DT.405699  DT.40271285  DT.97770268 

    Selected AceView cDNA sequences (see all 762):

    AW627469 CD620752 BI490003 CN482634 BE740515 AI927832 BF196042 BQ350308 
    AU104593 AW074105 BC069585 BE744077 BM129811 T95050 BX480249 BM850512 
    AA385463 BE271861 BM142248 CN483322 BM142377 CB243797 CR599089 BQ380667 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KRT86 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    KRT86 Expression
    About this image

    KRT86 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KRT86 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.278658

    UniProtKB/Swiss-Prot: KRT86_HUMAN, O43790
    Tissue specificity: Synthesis begins slightly higher in the hair shaft than HB1 and HB3 and continues much farther
    up, ending in the keratogeneous zone

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KRT86

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for KRT86 gene from Selected species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Krt861 , 5 keratin 861, 5 87.17(n)1
    87.24(a)1
      15 (56.90 cM)5
    166791  NM_010667.21  NP_034797.11 
     1014734785 


    ENSEMBL Gene Tree for KRT86 (if available)
    TreeFam Gene Tree for KRT86 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KRT86 gene
    KRT742  KRT772  KRT6B2  KRT832  KRT762  KRT32  KRT842  KRT82  
    KRT812  KRT712  KRT72  KRT792  KRT722  KRT732  KRT6C2  KRT52  
    KRT6A2  KRT852  KRT22  KRT752  KRT12  KRT822  KRT42  
    Selected SIMAP similar genes for KRT86 using alignment to 2 protein entries:     KRT86_HUMAN (see all proteins) (see all similar genes):
    KRTHB6    KRT121P    KRT81    KRTHB1    KRT83    KRT85
    KRT7    KRT75    KRT82    KRT84    KRTHB2    KRT1
    KRT8    KRT1B    KRT79    KRT6A    KRT74    KRT72

    Find genes that share paralogs with KRT86           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for KRT86
    PGOHUM00000257941 PGOHUM00000239783


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KRT86 (see all 311)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0230534
    Monilethrix (MLTRX)4--see VAR_0230532 N H mis40--------
    VAR_0181284
    Monilethrix (MLTRX)4--see VAR_0181282 E K mis40--------
    rs289396691,2,4
    Monilethrix (MLTRX)4--see VAR_0181262 mis40--------
    VAR_0181254
    Monilethrix (MLTRX)4--see VAR_0181252 N D mis40--------
    VAR_0181274
    Monilethrix (MLTRX)4--see VAR_0181272 E K mis40--------
    VAR_0181294
    Monilethrix (MLTRX)4--see VAR_0181292 E D mis40--------
    rs610918941,2
    Cpathogenic152530345(+) CCCTCA/C/GACAGC 3 N H D mis10--------
    rs606125751,2
    Cpathogenic152530358(+) GTTCGA/CGGCCT 2 E A mis10--------
    rs606876041,2
    Cpathogenic152534326(+) ACATCA/C/GAGATC 3 K Q E mis10--------
    rs1219091291,2
    Cpathogenic152534359(+) AGGGCA/GAGGAG 2 K E mis10--------

    HapMap Linkage Disequilibrium report for KRT86 (52643084 - 52702947 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for KRT86 (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv899089CNV Loss21882294
    nsv899088CNV Loss21882294
    nsv899087CNV Loss21882294
    nsv826378CNV Loss20364138
    dgv29e180CNV Gain20482838
    dgv200n27CNV Gain19166990
    esv29967CNV Gain17803354
    dgv70e55CNV Gain17911159
    nsv818917CNV Gain17921354
    nsv516938CNV Gain+Loss19592680

    Human Gene Mutation Database (HGMD): KRT86
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KRT86
    DNA2.0 Custom Variant and Variant Library Synthesis for KRT86

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 601928   
    OMIM disorders: 158000  
    UniProtKB/Swiss-Prot: KRT86_HUMAN, O43790
  • Monilethrix (MLTRX) [MIM:158000]: Autosomal dominant hair disorder characterized clinically by alopecia
    and follicular papules. Affected hairs have uniform elliptical nodes of normal thickness and intermittent
    constrictions, internodes at which the hair easily breaks. Usually only the scalp is involved, but in severe
    forms, the secondary sexual hair, eyebrows, eyelashes, and nails may also be affected. Note=The disease is caused
    by mutations affecting the gene represented in this entry

  • 5 diseases for KRT86:    
    About MalaCards
    monilethrix    hair disease    x-linked ichthyosis    epidermolytic hyperkeratosis
    pachyonychia congenita

    6 diseases from the University of Copenhagen DISEASES database for KRT86:
    Monilethrix     Epidermolytic hyperkeratosis     Epidermolysis bullosa simplex     Pachyonychia congenita
    Alopecia     Keratosis

    Find genes that share disorders with KRT86           About GenesLikeMe

    3 Novoseek inferred disease relationships for KRT86 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    monilethrix 97.5 27 18393232 (3), 10504448 (3), 15050877 (3), 12653715 (2) (see all 11)
    hyperkeratosis 50.2 1 14714571 (1)
    tumors 0 2 11948410 (1), 11801790 (1)

    Genetic Association Database (GAD): KRT86
    Human Genome Epidemiology (HuGE) Navigator: KRT86 (1 document)

    Export disorders for KRT86 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KRT86 gene, integrated from 10 sources (see all 44):
    (articles sorted by number of sources associating them with KRT86)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of novel mutations in basic hair keratins hHb1 and hHb6 in monilethrix: implications for protein structure and clinical phenotype. (PubMed id 10504448)1, 2, 9 Korge B.P....Munro C.S. (J. Invest. Dermatol. 1999)
    2. Two different mutations in the same codon of a type II hair keratin (hHb6) in patients with monilethrix. (PubMed id 10594761)1, 2, 9 Pearce E.G.... Bowden P.E. (J. Invest. Dermatol. 1999)
    3. Sequences and differential expression of three novel human type-II hair keratins. (PubMed id 9084137)1, 2, 9 Rogers M.A....Schweizer J. (Differentiation 1997)
    4. Monilethrix: a novel mutation (Glu402Lys) in the helix termination motif and the first causative mutation (Asn114Asp) in the helix initiation motif of the type II hair keratin hHb6. (PubMed id 10469314)1, 2, 9 Winter H.... Schweizer J. (J. Invest. Dermatol. 1999)
    5. Characterization and chromosomal localization of human hair-specific keratin genes and comparative expression during the hair growth cycle. (PubMed id 9457912)1, 2, 9 Bowden P.E.... Hodgins M.B. (J. Invest. Dermatol. 1998)
    6. New consensus nomenclature for mammalian keratins. (PubMed id 16831889)1, 3 Schweizer J....Wright M.W. (J. Cell Biol. 2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. A novel promoter polymorphism (-71C>T) in KRTHB6 gene in Indian population. (PubMed id 15183744)1, 4 Bairwa N.K.... Bamezai R. (Ann. Genet. 2004)
    9. Mutations in the hair cortex keratin hHb6 cause the inherited hair disease monilethrix. (PubMed id 9241275)1, 3 Winter H....Schweizer J. (Nat. Genet. 1997)
    10. A new mutation in the type II hair cortex keratin hHb1 involved in the inherited hair disorder monilethrix. (PubMed id 9402962)1, 2 Winter H....Schweizer J. (Hum. Genet. 1997)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3892 HGNC: 6463 AceView: KRTHB6andKRT7 Ensembl:ENSG00000170442 euGenes: HUgn3892
    ECgene: KRT86 H-InvDB: KRT86

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KRT86 Pharmacogenomics, SNPs, Pathways
    Human Intermediate Filament Mutation Databasehttp://www.interfil.org
    GeneReviewshttp://www.ncbi.nlm.nih.gov/books/NBK1116/?term=KRT86[genesymbol]

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KRT86 gene:
    Search GeneIP for patents involving KRT86

    GeneCards and IP:
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