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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KRT75 Gene

protein-coding   GIFtS: 45
GCID: GC12M052817

Keratin 75

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Keratin 751 2     PFB2 5
K6HF2 3 5     Cytokeratin Type II2
Keratin-6 Hair Follicle2 3     cytokeratin-752
Type II Keratin-K6hf2 3     Keratin, Type II Cytoskeletal 752
Type-II Keratin Kb182 3     keratin-752
CK-752 3     Type II Keratin-182
K752 3     Cytokeratin-753
KB182 3     Keratin-753
hK6hf2 3     

External Ids:    HGNC: 244311   Entrez Gene: 91192   Ensembl: ENSG000001704547   OMIM: 6090255   UniProtKB: O956783   

Export aliases for KRT75 gene to outside databases

Previous GC identifers: GC12M051105 GC12M049861


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for KRT75 Gene:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II
keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is
expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair
shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been
associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS).
(provided by RefSeq, Oct 2008)

GeneCards Summary for KRT75 Gene: 
KRT75 (keratin 75) is a protein-coding gene. Diseases associated with KRT75 include pseudofolliculitis barbae, and marek disease. GO annotations related to this gene include structural molecule activity. An important paralog of this gene is KRT74.

UniProtKB/Swiss-Prot: K2C75_HUMAN, O95678
Function: Plays a central role in hair and nail formation. Essential component of keratin intermediate filaments
in the companion layer of the hair follicle




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.2  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KRT75 gene promoter:
         TBP   AML1a   AP-1   Bach2   C/EBPalpha   GATA-2   CHOP-10   JunD   FOXC1   SEF-1 (1)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKRT75 promoter sequence
   Search SABiosciences Chromatin IP Primers for KRT75

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KRT75


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13   Ensembl cytogenetic band:  12q13.13   HGNC cytogenetic band: 12q13.13

KRT75 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KRT75 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M052817:  view genomic region     (about GC identifiers)

Start:
52,817,854 bp from pter      End:
52,828,309 bp from pter
Size:
10,456 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: K2C75_HUMAN, O95678 (See protein sequence)
Recommended Name: Keratin, type II cytoskeletal 75  
Size: 551 amino acids; 59560 Da
Subunit: Heterodimer of a type I and a type II keratin (By similarity). May associate with KRT17 (By similarity)
Miscellaneous: May be used as a marker of hair differentiation
Miscellaneous: There are two types of cytoskeletal and microfibrillar keratin, I (acidic) and II (neutral to
basic) (40-55 and 56-70 kDa, respectively)
Sequence caution: Sequence=BAG61056.1; Type=Erroneous initiation;
Secondary accessions: B4DQU4 Q9NSA9

Explore the universe of human proteins at neXtProt for KRT75: NX_O95678

Explore proteomics data for KRT75 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O95678

  • KRT75 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KRT75 Protein Expression
    REFSEQ proteins: NP_004684.2  
    ENSEMBL proteins: 
     ENSP00000252245  

    Human Recombinant Protein Products for KRT75: 
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for KRT75 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0045095keratin filament IEA--

    KRT75 for ontologies           About GeneDecksing



    KRT75 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for KRT75


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    IFF2: Intermediate filaments type II, keratins (basic)

    5 InterPro protein domains:
     IPR009053 Prefoldin
     IPR018039 Intermediate_filament_CS
     IPR001664 IF
     IPR016044 F
     IPR003054 Keratin_II

    Graphical View of Domain Structure for InterPro Entry O95678

    ProtoNet protein and cluster: O95678

    3 Blocks protein domains:
    IPB001664 Intermediate filament protein
    IPB002957 Type I keratin signature
    IPB003054 Type II keratin signature


    UniProtKB/Swiss-Prot: K2C75_HUMAN, O95678
    Similarity: Belongs to the intermediate filament family


    KRT75 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: K2C75_HUMAN, O95678
    Function: Plays a central role in hair and nail formation. Essential component of keratin intermediate filaments
    in the companion layer of the hair follicle

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005198structural molecule activity IEA--
         
    KRT75 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Krt75):
     integument 

    KRT75 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for KRT75 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for KRT75

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KRT75 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KRT75 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KRT75
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate KRT75:
    hsa-miR-633 hsa-miR-586 hsa-miR-642b hsa-miR-1256 hsa-miR-552
    SwitchGear 3'UTR luciferase reporter plasmidKRT75 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Clone
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KRT75


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KRT75

    5/65 Interacting proteins for KRT75 (O956783) via UniProtKB, MINT, STRING, and/or I2D (see all 65)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GABARAPO951663I2D: score=2 
    GABARAPL1Q9H0R83I2D: score=2 
    MAP1LC3AQ9H4923I2D: score=2 
    MAP1LC3BQ9GZQ83I2D: score=2 
    AMBRA1Q9C0C73I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KRT75 (K2C75)

    Search CenterWatch for drugs/clinical trials and news about KRT75 / K2C75

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KRT75 gene: 
    NM_004693.2  

    Unigene Cluster for KRT75:

    Keratin 75
    Hs.697046  [show with all ESTs]
    Unigene Representative Sequence: AK298960
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000252245(uc001saj.2)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KRT75
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate KRT75:
    hsa-miR-633 hsa-miR-586 hsa-miR-642b hsa-miR-1256 hsa-miR-552
    SwitchGear 3'UTR luciferase reporter plasmidKRT75 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for KRT75
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KRT75
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    GenScript: all cDNA clones in your preferred vector: KRT75 (NM_004693)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KRT75
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KRT75
    Sirion Biotech Customized lentivirus for stable overexpression of KRT75 
                         Customized lentivirus expression plasmids for stable overexpression of KRT75 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for KRT75
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KRT75
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KRT75

    Additional mRNA sequence: 

    AK225962.1 AK298960.1 Y17282.1 

    5 DOTS entries:

    DT.70104540  DT.92470158  DT.121119142  DT.121117540  DT.95147644 

    2 AceView cDNA sequences:

    NM_004693 Y17282 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KRT75 expression in normal human tissues (normalized intensities)      KRT75 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    KRT75 Expression
    About this image


    KRT75 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Hair (Integumentary System)    fully expand to see all 2 entries
             Fetal Inner Root Sheath Cells Inner Root Sheath
     
     Eye (Sensory Organs)
             limbal epithelial basal cells   
     
     Epithelium (Uncategorized)
             limbal epithelial basal cells   

     -- (Integumentary System)
             skin   

    See KRT75 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KRT75

    SOURCE GeneReport for Unigene cluster: Hs.697046

    UniProtKB/Swiss-Prot: K2C75_HUMAN, O95678
    Tissue specificity: Highly expressed in hair follicles from scalp. Specifically expressed in the of the hair
    companion layer follicle, a single layered band of flat and vertically oriented cells between the cuboidal outer
    root sheath (ORS) cells and the inner root sheath (IRS) that stretches from the lowermost bulb region to the
    isthmus of the follicle. Also expressed in medullated hairs. In nails, it is almost exclusively present in the
    nail bed (at protein level)

        SABiosciences Custom PCR Arrays for KRT75
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KRT75

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for KRT75 gene from 2/7 species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Krt751 , 5 keratin 751, 5 83.64(n)1
    85.09(a)1
      15 (56.91 cM)5
    1090521  NM_133357.31  NP_579935.11 
     1015633455 
    chicken
    (Gallus gallus)
    Aves KRT751 keratin 75 70.46(n)
    69.56(a)
      408041  NM_001001313.1  NP_001001313.1 


    ENSEMBL Gene Tree for KRT75 (if available)
    TreeFam Gene Tree for KRT75 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KRT75 gene
    KRT742  KRT772  KRT6B2  KRT832  KRT762  KRT32  KRT842  KRT862  
    KRT82  KRT812  KRT712  KRT72  KRT792  KRT722  KRT732  KRT6C2  
    KRT52  KRT6A2  KRT852  KRT22  KRT12  KRT822  KRT42  
    18/50 SIMAP similar genes for KRT75 using alignment to 1 protein entry:     K2C75_HUMAN(see all similar genes):
    KRT5    KRT6A    KRT6B    KRT6C    KRT79    KRT121P
    KRT7    KRTHB6    KRT1B    KRT72    KRT78    KRT86
    KRT8    KRT74    KRT4    KRT2    KRT71    KRT73

    KRT75 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for KRT75
    PGOHUM00000240526


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    UniProtKB/Swiss-Prot: K2C75_HUMAN, O95678
    Polymorphism: The Thr-161 variant may increase risk to develop pseudofolliculitis barbae (PFB) [MIM:612318]. PFB
    is a common hair disorder characterized by a pustular foreign body inflammatory reaction that is induced by
    ingrown hairs of the facial and submental (barbea) regions after regular shaving. It occurs predominantly in
    black males, while it is rather rare and usually far less severe in Caucasian males


    10/364 SNPs in KRT75 are shown (see all 364)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs22323981,2,4
    C,FLoose anagen hair syndrome (LAHS)4 --52658704(-) GGGCCG/AAGGCT 2 /K /E mis1 ese35Minor allele frequency- A:0.01NA EU 5999
    rs22323871,2,4
    C,F,A,Hother152661960(-) AGTTCG/ACCTCC 2 /T /A mis1 ese327Minor allele frequency- A:0.13NS EA NA WA CSA EU 8363
    rs678766061,2
    C--49861640(+) AAGGGC/-TGATG 1 -- ds50011Minor allele frequency- -:0.50NA 2
    rs111701181,2
    C,F,H--52651710(+) TTACTG/TGATAT 1 -- ds500111Minor allele frequency- T:0.04NS EA NA 1198
    rs733065441,2
    C,F--52651768(+) AAAGCG/ATTGCT 1 -- ds50012Minor allele frequency- A:0.03WA 120
    rs1395959211,2
    --52651823(+) TGCTGA/GGTCTG 1 -- ds50010--------
    rs780026261,2
    C,F--52651881(+) CACCCG/AGCGTC 1 -- ds50011Minor allele frequency- A:0.01WA 118
    rs1891877121,2
    --52651966(+) AGCTCC/TGGCTT 1 -- ds50010--------
    rs1473114731,2
    --52652032(+) CCTGCA/GCCTCT 1 -- ds50010--------
    rs730971491,2
    C,F--52652070(+) AGCTTT/ACTTAG 1 -- ds50013Minor allele frequency- A:0.12WA NA EA 358

    HapMap Linkage Disequilibrium report for KRT75 (52817854 - 52828309 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for KRT75:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1925677CNV Deletion18987734
    nsv832411CNV Loss17160897
    nsv832412CNV Loss17160897
    nsv520797CNV Gain19592680
    nsv832410CNV Gain17160897


    Human Gene Mutation Database (HGMD): KRT75
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing KRT75
    DNA2.0 Custom Variant and Variant Library Synthesis for KRT75

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609025   
    OMIM disorders: 612318  
    UniProtKB/Swiss-Prot: K2C75_HUMAN, O95678
  • Loose anagen hair syndrome (LAHS) [MIM:600628]: In LAHS, anagen hairs are easily pulled from the scalp.
    The hair is relatively sparse and does not grow long. Hair of fair color and hair shafts of reduced caliber, and
    an early age of onset are features. Usually the hairs are not fragile and there are no areas of breakage.
    Note=The disease may be caused by mutations affecting the gene represented in this entry

  • 12 diseases for KRT75:    About MalaCards
    pseudofolliculitis barbae    marek disease    loose anagen hair syndrome    fibrous histiocytoma
    histiocytoma    atopic dermatitis    alopecia    dermatitis
    lung cancer    esophagitis    breast cancer    hepatitis


    KRT75 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for KRT75 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 2 8950218 (1), 7515536 (1)


    Export disorders for KRT75 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KRT75 gene, integrated from 9 sources (see all 42):
    (articles sorted by number of sources associating them with KRT75)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel human type II cytokeratin, K6hf, specifically expressed in the companion layer of the hair follicle. (PubMed id 9856802)1, 2, 3, 9 Winter H.... Schweizer J. (1998)
    2. Characterization of a 300 kbp region of human DNA containing the type II hair keratin. (PubMed id 10692104)1, 2, 3 Rogers M.A.... Schweizer J. (2000)
    3. Is the loose anagen hair syndrome a keratin disorder? A clinical and molecular study. (PubMed id 11939812)1, 2, 9 Chapalain V.... Taieb A. (2002)
    4. New consensus nomenclature for mammalian keratins. (PubMed id 16831889)1, 3 Schweizer J....Wright M.W. (2006)
    5. An unusual Ala12Thr polymorphism in the 1A alpha-helical segment of the companion layer-specific keratin K6hf: evidence for a risk factor in the etiology of the common hair disorder pseudofolliculitis barbae. (PubMed id 15086549)1, 2 Winter H.... Schweizer J. (2004)
    6. Dermal papilla-induced hair differentiation of adult epithelial stem cells from human skin. (PubMed id 15292489)1, 2 Roh C.... Lyle S. (2004)
    7. Cytokeratin 75 expression in central, centrifugal, ci catricial alopecia--new observations in normal and diseased hair follicles. (PubMed id 19614992)1, 9 Sperling L.C....Darling T. (2010)
    8. The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus. (PubMed id 23084401)1 Singh G....Moore M.J. (2012)
    9. Breast carcinoma with brain metastases: clinical analy sis and immunoprofile on tissue microarrays. (PubMed id 21427063)1 Brogi E....Seidman A.D. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9119 HGNC: 24431 AceView: K6HF Ensembl:ENSG00000170454 euGenes: HUgn9119
    ECgene: KRT75 H-InvDB: KRT75

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KRT75 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KRT75 gene:
    Search GeneIP for patents involving KRT75

    GeneCards and IP:
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