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KRT5 Gene

protein-coding   GIFtS: 63

GC12M051194
keratin 5
(Previous names: epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types, keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: EBS2)
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Aliases &
Descriptions
for KRT5

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
CK-5 3
CK5 2
Cytokeratin-5 3
DDD 2, 5
EBS2 2
K5 2, 3
KRT5A 1, 2
Keratin-5 3
Descriptions
58 kDa cytokeratin 2, 3
epidermolysis bullosa simplex 2
Dowling-Meara/Kobner/Weber-Cockayne types 1, 2
keratin 5 2
keratin 5 (epidermolysis bullosa simplex,
Dowling-Meara/Kobner/Weber-Cockayne types) 1, 2
keratin, type II cytoskeletal 5 2
External Ids
HGNC: 64421
Entrez Gene: 38522
UniProtKB: P136473
Ensembl: ENSG000001860817
Search outside databases for aliases for KRT5 gene

Previous GC identifers: GC12M052976 GC12M052938 GC12M052625

Summaries
for KRT5

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for KRT5:
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins
consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains
coexpressed during differentiation of simple and stratified epithelial tissues. This type II
cytokeratin is specifically expressed in the basal layer of the epidermis with family member
KRT14. Mutations in these genes have been associated with a complex of diseases termed
epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome
12q12-q13. [provided by RefSeq]

Gene Wiki entry for KRT5 (Keratin_5)

Genomic Location
for KRT5

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the KRT5 gene  

Entrez Gene cytogenetic band: 12q12-q13   Ensembl cytogenetic band:  12q13.13   HGNC cytogenetic band: 12q

KRT5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M051194:     (about GC identifiers)

Start:
 51,194,626 bp from pter
End:
 51,200,510 bp from pter
Size:
 5,885 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000012.10  NT_029419.11  

Proteins
for KRT5

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: K2C5_HUMAN, P13647 (See protein sequence)
Recommended Name: Keratin, type II cytoskeletal 5  
Size: 590 amino acids; 62378 Da
Subunit: Heterotetramer of two type I and two type II keratins. Keratin-5 associates with
keratin-14. Interacts with TCHP
Miscellaneous: There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55
kDa) and II (neutral to basic; 56-70 kDa)
Secondary accessions: Q6PI71 Q6UBJ0 Q8TA91

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins: NP_000415.2  

    ENSEMBL proteins: 
    ENSP00000252242 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (Cytokeratin 5 + 18, Cytokeratin 5, Cytokeratin 5 + 8, Cytokeratin 5 + 14, basic Cytokeratin, Cytokeratin 1 - 8, Cytokeratin 5 + 6 + 8 + 18, Cytokeratin 4 + 5 + 6 + 8 + 10 + 13 + 18, Cytokeratin 5 + 6 + 18, Cytokeratin 5 + 6, Cytokeratin 1 + 5 + 10+ 14)
    Human Recombinant Proteins from Abnova (KRT5)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    1 Gene Ontology (GO) cellular component term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0045095 keratin filament IDA7679677
    About this table

    Antibodies for KRT5: 
    Invitrogen Antibodies for KRT5
    Millipore Mono- and Polyclonal Antibodies for the study of KRT5
    Sigma-Aldrich Antibody Arrays and Antibodies for KRT5
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (Cytokeratin 5 + 18, Cytokeratin 5, Cytokeratin 5 + 8, Cytokeratin 5 + 14, basic Cytokeratin, Cytokeratin 1 - 8, Cytokeratin 5 + 6 + 8 + 18, Cytokeratin 4 + 5 + 6 + 8 + 10 + 13 + 18, Cytokeratin 5 + 6 + 18, Cytokeratin 5 + 6, Cytokeratin 1 + 5 + 10+ 14), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (KRT5)
    Novus Biologicals Antibodies for KRT5

    Assays for KRT5: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for KRT5

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro domains/families:
     IPR001664 IF
     IPR016044 F
     IPR018039 Intermediate_filament_CS
     IPR003054 Keratin_II


       GeneDecks  KRT5 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry P13647

    ProtoNet protein and cluster: P13647

    3 Blocks protein families:
    IPB001664 Intermediate filament protein
    IPB002957 Type I keratin signature
    IPB003054 Type II keratin signature


    UniProtKB/Swiss-Prot: K2C5_HUMAN, P13647
    Similarity: Belongs to the intermediate filament family

    Gene Function
    for KRT5

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (KRT5)
    Browse for Gene Knock-down Tools from Millipore
    Browse Abnova for Chimera RNAi Products
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000424

                  Applied Biosystems Silencer® siRNAs for KRT5

                  Sigma-Aldrich siRNA for KRT5  
                         Sigma-Aldrich shRNA for KRT5  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for KRT5
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_000424
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_000424
                                     untagged cDNA clone in CMV expression vector: NM_000424 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_000424

    Genatlas biochemistry entry for KRT5:
    keratin 5,type II,basal layer,dimerizing with KRT14

    6 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Krt5):

    behavior/neurologicalcraniofacialdigestive/alimentarylethality-prenatal/perinatallimbs/digits/tail
    skin/coat/nails

    2 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005200 structural constituent of cytoskeleton TAS7520042
    GO:0005515 protein binding IPI10727209
    About this table

    Pathways & Interactions
    for KRT5

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    1 Millipore Pathway for KRT5
     Cytoskeleton remodeling Keratin filaments

       GeneDecks  KRT5 for the pathways selected above  
    About GeneDecksing

     Gene Network CentralTM Interacting Genes and Proteins Network for  KRT5 


    5/22 Interacting proteins for KRT5 (P136471 ENSP000002522423) via UniProtKB, MINT, and/or STRING (see all 22 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ALOX12P180541, ENSP000002515353EBI-702187, EBI-1633210 STRING (score=.721)
    EGFRENSP000002754933STRING (score=.912)
    ERBB2ENSP000002695713STRING (score=.875)
    BOCENSP000002733953STRING (score=.853)
    AMELXENSP000003700883STRING (score=.841)
    About this table

    1 Gene Ontology (GO) biological process term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008544 epidermis development TAS7520042
    About this table

    Drugs & Compounds
    for KRT5

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for KRT5
    10/14 Novoseek chemical compound relationships for KRT5 gene (see all 14 )
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    kalinin 71.38 1 7530560 (1)
    asparagine 20.12 2 15102078 (1), 7534039 (1)
    progesterone 18.84 12 16241993 (1), 19221640 (1), 16266999 (1), 17968031 (1) (see all 8)
    12-o-tetradecanoylphorbol 13-acetate 9.73 1 17219416 (1)
    lysine 5.15 3 14723728 (2), 7534039 (1)
    calcium 2.31 3 1373746 (1), 1599900 (1)
    threonine 0.00 1 14723728 (1)
    urea 0.00 1 1370674 (1)
    leucine 0.00 2 7686424 (1)
    histidine 0.00 1 10730767 (1)
    About this table


    Transcripts
    for KRT5

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (KRT5)
    Browse for Gene Knock-down Tools from Millipore
    Browse Abnova for Chimera RNAi Products
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000424

                  Sigma-Aldrich siRNA for KRT5  
                         Sigma-Aldrich shRNA for KRT5  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_000424  

    REFSEQ mRNAs for KRT5 gene: 

    NM_000424.3   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_000424  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_000424
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_000424
                                     untagged cDNA clone in CMV expression vector: NM_000424 

    Additional cDNA sequence: 

    AK093720.1 AK296823.1 AK303972.1 AK310827.1 AY373434.1 BC024292.1 BC042132.1 BC071906.1 
    M19723.1 M21389.1 

    24/87 DOTS entries (see all 87 ):

    DT.95147644  DT.97861421  DT.92470157  DT.91647885  DT.97845743  DT.121119205  DT.92049484  DT.95214039 
    DT.95174976  DT.97845772  DT.121118495  DT.121118296  DT.92470136  DT.92408071  DT.100805796  DT.121118151 
    DT.121118662  DT.121118882  DT.121118114  DT.121118281  DT.121118676  DT.121118613  DT.95147651  DT.100805805 

    24/404 AceView cDNA sequences (see all 404 ):

    AW366728 BF838929 CR612432 BF915078 AW243951 BF876882 AK093720 BF914819 
    BF831594 BQ378588 AW366724 AA583975 BT006899 BE140567 AX748277 AW946461 
    AA586890 BQ350594 BF149187 BQ330386 BF873253 BC008807 BF915071 BQ352445 

    highest scoring ESTs for KRT5:

    M21389 AK093720 BC024292 BC042132 BC071906 BG876882 BQ312727 BQ348250 BQ348583 BQ348598 

    Unigene Cluster for KRT5:

    Keratin 5
    Hs.433845  [show with all ESTs]
    Unigene Representative Sequence: M21389


    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for KRT5 (see all 6 )

    ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11
    SP1:                                                                    -                       -               
    SP2:                                                                    -                                       
    SP3:                                                                                                            
    SP4:                                                                                                            
    SP5:                                                                                                            

    About this scheme

    ECgene alternative splicing isoforms for KRT5

    1 Ensembl transcript including schematic representation:
    ENST00000252242  

    Expression
    for KRT5

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    KRT5 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for KRT5

    1 / 2 / 3

    3 probe-sets matching KRT5 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    613_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 M21389 1.00 1.00 1.00 1

    		201820_at2, 3 U133-A 1 1.00 1.00 -- -- NM_000424 0.60 1.00 0.82 1

    		201820_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  KRT5 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: GCCCCTGCTG

    SOURCE GeneReport for Unigene cluster: Hs.433845

    Expression variation in blood from EXPOLDB for KRT5

    Orthologs
    for KRT5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for KRT5 gene from 3 species
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    cow
    (Bos taurus)    		 KRT51   -- keratin 5 91.21(n)
    95.58(a)    		 281268  NM_001008663.1  NP_001008663.1 
    mouse
    (Mus musculus)    		 Krt51, 5 15 (58.79 cM)5
    		 keratin 51, 5 87.07(n)1
    90.17(a)1    		 1103081  NM_027011.21  NP_081287.11 
     AF3067855  AK0143635  (see all 9)
    chicken
    (Gallus gallus)    		 KRT51   -- keratin 5 74(n)
    76.06(a)    		 407779  NM_001001195.1  NP_001001195.1 
    About this table        Species with no ortholog for KRT5

    ENSEMBL Gene Tree for KRT5

    Paralogs
    for KRT5

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for KRT5 gene
    KRT6B2  KRT752  KRT6C2  KRT6A2  

    SNPs/Variants
    for KRT5

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section

    		  --

    Disorders & Mutations
    for KRT5

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 148040   disorders: 131760  131900  131800  131960  179850  609352  

    UniProtKB/Swiss-Prot: K2C5_HUMAN, P13647

  • Defects in KRT5 are a cause of epidermolysis bullosa simplex Dowling-Meara type (DM-EBS)
    [MIM:131760]. DM-EBS is a severe form of intraepidermal epidermolysis bullosa characterized by
    generalized herpetiform blistering, milia formation, dystrophic nails, and mucous membrane
    involvement
  • Defects in KRT5 are the cause of epidermolysis bullosa simplex with migratory circinate
    erythema (EBSMCE) [MIM:609352]. EBSMCE is a form of intraepidermal epidermolysis bullosa
    characterized by unusual migratory circinate erythema. Skin lesions appear from birth primarily on
    the hands, feet, and legs but spare nails, ocular epithelia and mucosae. Lesions heal with brown
    pigmentation but no scarring. Electron microscopy findings are distinct from those seen in the
    DM-EBS, with no evidence of tonofilament clumping
  • Defects in KRT5 are a cause of epidermolysis bullosa simplex Weber-Cockayne type (WC-EBS)
    [MIM:131800]. WC-EBS is a form of intraepidermal epidermolysis bullosa characterized by blistering
    limited to palmar and plantar areas of the skin
  • Defects in KRT5 are a cause of epidermolysis bullosa simplex Koebner type (K-EBS)
    [MIM:131900]. K-EBS is a form of intraepidermal epidermolysis bullosa characterized by generalized
    skin blistering. The phenotype is not fundamentally distinct from the Dowling-Meara type,
    althought it is less severe
  • Defects in KRT5 are the cause of epidermolysis bullosa simplex with mottled pigmentation
    (MP-EBS) [MIM:131960]. MP-EBS is a form of intraepidermal epidermolysis bullosa characterized by
    blistering at acral sites and 'mottled' pigmentation of the trunk and proximal extremities with
    hyper- and hypopigmentation macules
  • Defects in KRT5 are the cause of Dowling-Degos disease (DDD) [MIM:179850]; also known as
    Dowling-Degos-Kitamura disease or reticulate acropigmentation of Kitamura. DDD is an autosomal
    dominant genodermatosis. Affected individuals develop a postpubertal reticulate hyperpigmentation
    that is progressive and disfiguring, and small hyperkeratotic dark brown papules that affect
    mainly the flexures and great skin folds. Patients usually show no abnormalities of the hair or
    nails

    • 10/43 Novoseek disease relationships for KRT5 gene (see all 43 )

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    epidermolysis bullosa simplex 97.15 77 12655565 (3), 12648226 (3), 15347343 (3), 10782015 (2) (see all 54)
    ebs-mp 92.33 4 10494094 (1), 8799157 (1), 16581562 (1), 15982306 (1)
    epidermolysis bullosa 76.87 2 8435522 (1), 7537032 (1)
    ichthyosis 63.11 2 16417221 (1)
    keratoderma palmoplantar 62.47 2 16417221 (1)
    skin diseases 57.15 4 9989794 (1), 12655565 (1), 17039244 (1)
    bullous congenital ichthyosiform erythroderma 56.54 1 10903910 (1)
    breast carcinoma 51.82 8 16241993 (2), 16938528 (1), 17123107 (1), 16012853 (1) (see all 6)
    hyperkeratosis 50.21 1 11407989 (1)
    carcinoma ductal 46.16 4 16241993 (2), 17522367 (1), 17123107 (1)
    About this table

    GeneTests: KRT5
    Epidermolysis Bullosa Simplex

    Human Gene Mutation Database: KRT5
    Genetic Association Database: KRT5
    Human Genome Epidemiology Navigator: KRT5 (2 documents)

    Medical News
    for KRT5

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for KRT5

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/314 PubMed articles for KRT5 gene (see all 314 ):

    Search for KRT5

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing KRT5

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 3852 HGNC: 6442 AceView: KRT5 Ensembl:ENSG00000186081 euGenes: HUgn3852
    ECgene: KRT5 H-InvDB: KRT5

    Other Databases showing KRT5

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing KRT5

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    Human Intermediate Filament Mutation Databasehttp://www.interfil.org
    GeneReviewshttp://www.genetests.org/query?gene=KRT5

    Licensable Technologies
    for KRT5

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for KRT5

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for KRT5:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for KRT5-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for KRT5 Antibodies for KRT5
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for KRT5 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
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    (Cytokeratin 5 + 18, Cytokeratin 5, Cytokeratin 5 + 8, Cytokeratin 5 + 14, basic Cytokeratin, Cytokeratin 1 - 8, Cytokeratin 5 + 6 + 8 + 18, Cytokeratin 4 + 5 + 6 + 8 + 10 + 13 + 18, Cytokeratin 5 + 6 + 18, Cytokeratin 5 + 6, Cytokeratin 1 + 5 + 10+ 14)
     Antibodies (Cytokeratin 5 + 18, Cytokeratin 5, Cytokeratin 5 + 8, Cytokeratin 5 + 14, basic Cytokeratin, Cytokeratin 1 - 8, Cytokeratin 5 + 6 + 8 + 18, Cytokeratin 4 + 5 + 6 + 8 + 10 + 13 + 18, Cytokeratin 5 + 6 + 18, Cytokeratin 5 + 6, Cytokeratin 1 + 5 + 10+ 14)
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     Antibodies for KRT5

    GeneCards Homepage    -    Last full update: 2 Jul 2009        Incremental update: 13 Oct 2009

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