Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KRT39 Gene

protein-coding   GIFtS: 42
GCID: GC17M039114

Keratin 39

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Keratin 391 2     cytokeratin-392
Type I Hair Keratin Ka352 3     Keratin, Type I Cytoskeletal 392
CK-392 3     keratin-392
K392 3     Cytokeratin-393
KA352 3     Keratin-393

External Ids:    HGNC: 329711   Entrez Gene: 3907922   Ensembl: ENSG000001968597   UniProtKB: Q6A1633   

Export aliases for KRT39 gene to outside databases

Previous GC identifers: GC17M036369 GC17M034909


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for KRT39 Gene:
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate
filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament.
These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells.
The type I keratin genes are clustered in a region of chromosome 17q12-q21. (provided by RefSeq, Jul 2009)

GeneCards Summary for KRT39 Gene: 
KRT39 (keratin 39) is a protein-coding gene. Diseases associated with KRT39 include visceral leishmaniasis, and leishmaniasis. GO annotations related to this gene include structural molecule activity. An important paralog of this gene is KRT34.

UniProtKB/Swiss-Prot: K1C39_HUMAN, Q6A163
Function: May play a role in late hair differentiation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.2  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KRT39 gene promoter:
         AML1a   FOXF2   Pax-5   GCNF   FOXO3   FOXO3b   FAC1   GCNF-1   FOXO3a   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKRT39 promoter sequence
   Search SABiosciences Chromatin IP Primers for KRT39

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KRT39


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.2   Ensembl cytogenetic band:  17q21.2   HGNC cytogenetic band: 17q21.2

KRT39 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KRT39 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M039114:  view genomic region     (about GC identifiers)

Start:
39,114,669 bp from pter      End:
39,123,144 bp from pter
Size:
8,476 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: K1C39_HUMAN, Q6A163 (See protein sequence)
Recommended Name: Keratin, type I cytoskeletal 39  
Size: 491 amino acids; 55651 Da
Subunit: Heterotetramer of two type I and two type II keratins
Developmental stage: During differentiation of the hair, it is one of the last keratins expressed
Miscellaneous: There are two types of cytoskeletal and microfibrillar keratin, I (acidic) and II (neutral to
basic) (40-55 and 56-70 kDa, respectively)
Secondary accessions: B2RXK6 Q6IFU6

Explore the universe of human proteins at neXtProt for KRT39: NX_Q6A163

Explore proteomics data for KRT39 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6A163

  • KRT39 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KRT39 Protein Expression
    REFSEQ proteins: NP_998821.3  
    ENSEMBL proteins: 
     ENSP00000347823   ENSP00000464180  

    Human Recombinant Protein Products for KRT39: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for KRT39
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for KRT39
    GenScript Custom Purified and Recombinant Proteins Services for KRT39
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for KRT39 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005882intermediate filament IEA--

    KRT39 for ontologies           About GeneDecksing



    KRT39 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for KRT39
    GenScript Custom Superior Antibodies Services for KRT39
    Novus Biologicals KRT39 Antibody
    Abcam antibodies for KRT39
    Cloud-Clone Corp. Antibodies for KRT39 
    Search ThermoFisher Antibodies for KRT39
    LSBio Antibodies in human, mouse, rat for KRT39 

    Assay Products for KRT39: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for KRT39
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for KRT39
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for KRT39 
    Cloud-Clone Corp. CLIAs for KRT39


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    IFF1: Intermediate filaments type I, keratins (acidic)

    4 InterPro protein domains:
     IPR018039 Intermediate_filament_CS
     IPR001664 IF
     IPR016044 F
     IPR002957 Keratin_I

    Graphical View of Domain Structure for InterPro Entry Q6A163

    ProtoNet protein and cluster: Q6A163

    2 Blocks protein domains:
    IPB001664 Intermediate filament protein
    IPB002957 Type I keratin signature


    UniProtKB/Swiss-Prot: K1C39_HUMAN, Q6A163
    Similarity: Belongs to the intermediate filament family


    KRT39 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: K1C39_HUMAN, Q6A163
    Function: May play a role in late hair differentiation

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005198structural molecule activity IEA--
         
    KRT39 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for KRT39:
     Decreased POU5F1-GFP protein e 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for KRT39 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for KRT39

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KRT39 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KRT39 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KRT39
    1 QIAGEN miScript miRNA Assays for microRNA that regulate KRT39:
    hsa-miR-20b*
    SwitchGear 3'UTR luciferase reporter plasmidKRT39 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for KRT39
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KRT39

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for KRT39
    Sirion Biotech Customized adenovirus for overexpression of KRT39

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for KRT39 (see all 6)
    OriGene ORF clones in mouse, rat for KRT39
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KRT39 (NM_213656)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KRT39
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KRT39
    Sirion Biotech Customized lentivirus for stable overexpression of KRT39 
                         Customized lentivirus expression plasmids for stable overexpression of KRT39 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for KRT39
    Search LifeMap BioReagents cell lines for KRT39
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KRT39


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KRT39

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KRT39 (K1C39)

    Search CenterWatch for drugs/clinical trials and news about KRT39 / K1C39

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KRT39 gene: 
    NM_213656.3  

    Unigene Cluster for KRT39:

    Keratin 39
    Hs.28467  [show with all ESTs]
    Unigene Representative Sequence: NM_213656
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000355612(uc002hvo.1 uc010wfm.1) ENST00000578078 ENST00000578029

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KRT39
    1 QIAGEN miScript miRNA Assays for microRNA that regulate KRT39:
    hsa-miR-20b*
    SwitchGear 3'UTR luciferase reporter plasmidKRT39 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for KRT39
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KRT39
    Clone
    Products:
         
    OriGene clones in human, mouse for KRT39 (see all 6)
    OriGene ORF clones in mouse, rat for KRT39
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KRT39 (NM_213656)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KRT39
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KRT39
    Sirion Biotech Customized lentivirus for stable overexpression of KRT39 
                         Customized lentivirus expression plasmids for stable overexpression of KRT39 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for KRT39
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KRT39
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KRT39
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KRT39

    Additional mRNA sequence: 

    AJ786657.1 BC157887.1 BC171907.1 

    2 DOTS entries:

    DT.102819723  DT.40110750 

    6 AceView cDNA sequences:

    BK004054 AJ786657 R63932 BX090195 NM_213656 R64023 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KRT39 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTCCTGCCAG
    KRT39 Expression
    About this image


    See KRT39 Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.28467

    UniProtKB/Swiss-Prot: K1C39_HUMAN, Q6A163
    Tissue specificity: Expressed in skin and scalp. In the hair follicle, it is present in the upper hair cuticle and
    the upper cortex. Also present in the in the upper portion of beard hairs (at protein level)

        SABiosciences Custom PCR Arrays for KRT39
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for KRT39
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KRT39
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KRT39
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KRT39
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KRT39

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for KRT39 gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Krt391 , 5 keratin 391, 5 79.86(n)1
    74.79(a)1
      11 (62.92 cM)5
    2379341  NM_213730.21  NP_998895.21 
     995141145 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 3)
    Keratin aHA1; Uncharacterized protein
    (see all 3)
    49(a)
    38(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    6(70606275-70614367)
    6(70591466-70598937)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:923806
    --
    --
    31(a)
    19(a)
    possible ortholog
    possible ortholog
    9(48849051-48881933)
    1(59908885-59915757)


    ENSEMBL Gene Tree for KRT39 (if available)
    TreeFam Gene Tree for KRT39 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KRT39 gene
    KRT342  KRT172  KRT162  KRT312  KRT252  KRT402  KRT372  KRT272  
    KRT322  KRT382  KRT362  KRT192  KRT282  KRT142  KRT132  KRT262  
    KRT102  KRT122  KRT352  KRT152  KRT242  KRT92  KRT33B2  KRT33A2  
    18/35 SIMAP similar genes for KRT39 using alignment to 2 protein entries:     K1C39_HUMAN (see all proteins) (see all similar genes):
    KRT15    KRT14    KRT19    KRT33A    KRT34    K14
    KRT33B    KRT35    FLJ40504    KRT31    JUP    KRT32
    KRT17    KRT13    KRT36    KRT9    KRTHA7    KRT10

    KRT39 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/327 SNPs in KRT39 are shown (see all 327)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs105376431,2
    C--34912246(+) aaaag-/A/AA  
            
    aaaaa
    1 -- int12NA CSA 4
    rs1996968851,2
    C--34917182(+) GTGTA-/TGTG  
            
    TGTGT
    1 -- int10--------
    rs1889777001,2
    --34917183(+) TGTATC/GTGTGT 1 -- int10--------
    rs713000411,2
    C--39116961(-) GAGAAAGAG/-  
            
    AGAAA
    1 -- int11Minor allele frequency- -:0.50NA 2
    rs674957571,2
    C--39117388(+) AAAAG-/A/AA  
            
    AAAAA
    1 -- int10--------
    rs30676461,2
    C--39121022(+) TAAAATAAAA/
            
    AATCC
    1 -- int12Minor allele frequency- -:0.25NA CSA 4
    rs1124877111,2
    C--39121292(+) AAATAT/AAAAAA 1 -- int11Minor allele frequency- A:0.50WA 2
    rs348925831,2
    C--39122320(+) GTGTG-/TGTGTGT 1 -- int10--------
    rs58203781,2
    C--39123131(+) GTTTGT/-TTCCA 1 -- ut512Minor allele frequency- -:0.00CSA 6
    rs99078021,2
    C,F--39124706(+) ggattT/Gctggg 1 -- us2k12Minor allele frequency- G:0.33WA CSA 3

    HapMap Linkage Disequilibrium report for KRT39 (39114669 - 39123144 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for KRT39:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv908230CNV Loss21882294
    nsv9550CNV Loss18304495

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing KRT39
    DNA2.0 Custom Variant and Variant Library Synthesis for KRT39

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for KRT39:    About MalaCards
    visceral leishmaniasis    leishmaniasis

    1 disease from the University of Copenhagen DISEASES database for KRT39:
    Visceral leishmaniasis

    KRT39 for disorders           About GeneDecksing


    Export disorders for KRT39 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KRT39 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with KRT39)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Novel type I hair keratins K39 and K40 are the last to be expressed in differentiation of the hair: completion of the human hair keratin catalog. (PubMed id 17301834)1, 2 Langbein L....Schweizer J. (2007)
    2. New consensus nomenclature for mammalian keratins. (PubMed id 16831889)1, 3 Schweizer J....Wright M.W. (2006)
    3. Comprehensive analysis of keratin gene clusters in humans and rodents. (PubMed id 15085952)1, 2 Hesse M.... Magin T.M. (2004)
    4. The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain. (PubMed id 15617563)1, 2 Rogers M.A.... Schweizer J. (2004)
    5. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 390792 HGNC: 32971 AceView: KA35 Ensembl:ENSG00000196859 euGenes: HUgn390792
    ECgene: KRT39 H-InvDB: KRT39

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KRT39 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KRT39 gene:
    Search GeneIP for patents involving KRT39

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for KRT39  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for KRT39  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for KRT39  
     OriGene qSTAR qPCR primer pairs in human, mouse for KRT39   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for KRT39   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for KRT39   OriGene Custom Protein Services for KRT39  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KRT39
     QIAGEN SeqTarget long-range PCR primers for resequencing KRT39
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KRT39
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KRT39
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KRT39
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KRT39
     GenScript Custom Purified and Recombinant Proteins Services for KRT39 GenScript cDNA clones with any tag delivered in your preferred vector for KRT39
     GenScript Custom Assay Services for KRT39 GenScript Custom Superior Antibodies Services for KRT39
     GenScript Custom overexpressing Cell Line Services for KRT39 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in KRT39 promoter
     Search Chromatin IP Primers for KRT39
     RT2 qPCR Primer Assay in human, mouse, rat KRT39
     Search GNC Networks for KRT39
     SABiosciences Custom PCR Arrays for KRT39
     Search Tocris compounds for KRT39 (K1C39)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     KRT39 antibodies
     Antibodies for KRT39
     See all of Abcam's Antibodies, Kits and Proteins for KRT39
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for KRT39
     Antibodies for KRT39
     ELISAs for KRT39
     CLIAs for KRT39
     Search LifeMap BioReagents cell lines for KRT39
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KRT39
     SwitchGear 3'UTR luciferase reporter plasmids for KRT39
     SwitchGear Promoter luciferase reporter plasmids for KRT39
     Search ThermoFisher Antibodies for KRT39
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KRT39
     inGenious Targeting Laboratory - Custom generated mouse model solutions for KRT39
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for KRT39
    Customized:
     lentivirus for stable overexpression of KRT39
     lentivirus expression plasmids for stable overexpression of KRT39
     adenovirus for overexpression of KRT39
     LSBio Antibodies in human, mouse, rat for KRT39
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      KRT39 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4