Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



KRT25 Gene

protein-coding   GIFtS: 45
GCID: GC17M038904

Keratin 25

(Previous name: keratin 25A)
(Previous symbol: KRT25A)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Keratin 251 2     Keratin, Type I Cytoskeletal 252
KRT25A1 2 3     keratin-252
Keratin 25A1 2     keratin-25A2
Type I Inner Root Sheath-Specific Keratin-K25irs12 3     Type I Inner Root Sheath Specific Keratin 25 Irs12
CK-252 3     Cytokeratin-253
K252 3     Keratin-253
K25A2 3     Keratin-25A3
cytokeratin-252     

External Ids:    HGNC: 308391   Entrez Gene: 1471832   Ensembl: ENSG000002048977   UniProtKB: Q7Z3Z03   

Export aliases for KRT25 gene to outside databases

Previous GC identifers: GC17M036159 GC17M034698


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for KRT25 Gene:
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate
filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament.
These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells.
The type I keratin genes are clustered in a region of chromosome 17q12-q21. (provided by RefSeq, Jul 2009)

GeneCards Summary for KRT25 Gene:
KRT25 (keratin 25) is a protein-coding gene. GO annotations related to this gene include structural molecule activity. An important paralog of this gene is KRT34.

UniProtKB/Swiss-Prot: K1C25_HUMAN, Q7Z3Z0
Function: Essential for the proper assembly of type I and type II keratin protein complexes and formation of
keratin intermediate filaments in the inner root sheath (irs) (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KRT25 gene promoter:
         Spz1   NCX/Ncx   HTF   AP-2gamma   MZF-1   PPAR-gamma1   S8   c-Myb   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKRT25 promoter sequence
   Search Chromatin IP Primers for KRT25

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KRT25


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.2   Ensembl cytogenetic band:  17q21.2   HGNC cytogenetic band: 17q21.2

KRT25 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KRT25 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M038904:  view genomic region     (about GC identifiers)

Start:
38,904,273 bp from pter      End:
38,911,584 bp from pter
Size:
7,312 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: K1C25_HUMAN, Q7Z3Z0 (See protein sequence)
Recommended Name: Keratin, type I cytoskeletal 25  
Size: 450 amino acids; 49318 Da
Subunit: Heterotetramer of two type I and two type II keratins. Interacts with KRT6A to form filaments (By
similarity)
Miscellaneous: There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II
(neutral to basic; 56-70 kDa)

Explore the universe of human proteins at neXtProt for KRT25: NX_Q7Z3Z0

Explore proteomics data for KRT25 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KRT25 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_853512.1  
    ENSEMBL proteins: 
     ENSP00000310573  

    KRT25 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for KRT25
    OriGene Custom MassSpec
    OriGene Custom Protein Services for KRT25
    GenScript Custom Purified and Recombinant Proteins Services for KRT25
    Novus Biologicals KRT25 Protein
    Novus Biologicals KRT25 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for KRT25

     
    Search eBioscience for Proteins for KRT25 

     
    antibodies-online proteins for KRT25 (6 products) 

     
    antibodies-online peptides for KRT25

    KRT25 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for KRT25
    Novus Biologicals KRT25 Antibody
    Abcam antibodies for KRT25
    Cloud-Clone Corp. Antibodies for KRT25
    Search ThermoFisher Antibodies for KRT25
    antibodies-online antibodies for KRT25 (15 products) 

    KRT25 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for KRT25
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for KRT25
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for KRT25
    Cloud-Clone Corp. CLIAs for KRT25
    Search eBioscience for ELISAs for KRT25 
    antibodies-online kits for KRT25 (10 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    IFF1: Intermediate filaments type I, keratins (acidic)

    2 InterPro protein domains:
     IPR001664 IF
     IPR002957 Keratin_I

    Graphical View of Domain Structure for InterPro Entry Q7Z3Z0

    ProtoNet protein and cluster: Q7Z3Z0

    2 Blocks protein domains:
    IPB001664 Intermediate filament protein
    IPB002957 Type I keratin signature


    UniProtKB/Swiss-Prot: K1C25_HUMAN, Q7Z3Z0
    Similarity: Belongs to the intermediate filament family


    Find genes that share domains with KRT25           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: K1C25_HUMAN, Q7Z3Z0
    Function: Essential for the proper assembly of type I and type II keratin protein complexes and formation of
    keratin intermediate filaments in the inner root sheath (irs) (By similarity)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005198structural molecule activity IEA--
    GO:0005515protein binding ----
         
    Find genes that share ontologies with KRT25           About GenesLikeMe


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Krt25):
     endocrine/exocrine gland  growth/size/body  integument 

    Find genes that share phenotypes with KRT25           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for KRT25

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat KRT25 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate KRT25
    SwitchGear 3'UTR luciferase reporter plasmidKRT25 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for KRT25
    Predesigned siRNA for gene silencing in human, mouse, rat KRT25

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for KRT25

    Clone
    Products:
         
    OriGene clones in human, mouse for KRT25 (see all 5)
    OriGene ORF clones in mouse, rat for KRT25
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KRT25 (NM_181534)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KRT25
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KRT25

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for KRT25
    Browse ESI BIO Cell Lines and PureStem Progenitors for KRT25 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KRT25


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    K1C25_HUMAN, Q7Z3Z0: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton3
    cytosol2
    mitochondrion2
    nucleus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005737cytoplasm IEA--
    GO:0005882intermediate filament IEA--

    Find genes that share ontologies with KRT25           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KRT25
    Interactions:

        Search GeneGlobe Interaction Network for KRT25

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for KRT25 (ENSP000003105734) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--
    GO:0031069hair follicle morphogenesis IEA--
    GO:0045109intermediate filament organization IEA--

    Find genes that share ontologies with KRT25           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KRT25 (K1C25)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for KRT25 gene: 
    NM_181534.3  

    Unigene Cluster for KRT25:

    Keratin 25
    Hs.55412  [show with all ESTs]
    Unigene Representative Sequence: NM_181534
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000312150(uc002hve.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat KRT25 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate KRT25
    SwitchGear 3'UTR luciferase reporter plasmidKRT25 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for KRT25
    Predesigned siRNA for gene silencing in human, mouse, rat KRT25
    Clone
    Products:
         
    OriGene clones in human, mouse for KRT25 (see all 5)
    OriGene ORF clones in mouse, rat for KRT25
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KRT25 (NM_181534)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KRT25
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KRT25
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for KRT25
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KRT25
      QuantiTect SYBR Green Assays in human, mouse, rat KRT25
      QuantiFast Probe-based Assays in human, mouse, rat KRT25

    Additional mRNA sequence: 

    AJ564204.1 AK129503.1 

    1 DOTS entry:

    DT.95184218 

    15 AceView cDNA sequences:

    NM_181534 AI088272 W20364 AJ564204 AI150740 AJ564205 AK129503 AI150703 
    NM_181539 BX110062 W73634 W73682 W35097 W67642 W67826 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    KRT25 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTAAGAAAA
    KRT25 Expression
    About this image


    KRT25 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Epithelial Cells
             Fetal Inner Root Sheath Cells Inner Root Sheath
     
     Hair (Integumentary System)
             Fetal Inner Root Sheath Cells Inner Root Sheath
     
     Brain (Nervous System)
             Cerebellum
     
     Heart (Cardiovascular System)
    KRT25 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KRT25 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.55412

    UniProtKB/Swiss-Prot: K1C25_HUMAN, Q7Z3Z0
    Tissue specificity: Strongly expressed in skin and scalp, and weak expression observed in thymus and tongue. In
    the hair follicle, expressed in Henle layer, Huxley layer and in the inner root sheath cuticle of the hair
    follicle. Expression extends from the bulb region up to the point of differentiation into the three layers. Also
    present in the medulla of beard hair (at protein level)

        Custom PCR Arrays for KRT25
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for KRT25
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KRT25
    QuantiTect SYBR Green Assays in human, mouse, rat KRT25
    QuantiFast Probe-based Assays in human, mouse, rat KRT25
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KRT25

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for KRT25 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Krt251 , 5 keratin 251, 5 87.29(n)1
    91.93(a)1
      11 (62.92 cM)5
    708101  NM_133730.11  NP_598491.11 
     993155165 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    47(a)
    many ↔ many
    6(70410921-70423920)


    ENSEMBL Gene Tree for KRT25 (if available)
    TreeFam Gene Tree for KRT25 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for KRT25 gene
    KRT342  KRT172  KRT162  KRT312  KRT392  KRT402  KRT202  KRT372  
    KRT272  KRT322  KRT382  KRT362  KRT192  KRT282  KRT142  KRT132  
    KRT262  KRT102  KRT122  KRT352  KRT152  KRT242  KRT33B2  KRT92  
    KRT33A2  
    Selected SIMAP similar genes for KRT25 using alignment to 1 protein entry:     K1C25_HUMAN(see all similar genes):
    KRT27    KRT28    KRT26    KRT10    KRT19    KRT15
    KRT24    keratin    JUP    KRT13    KRT12    KRT14
    KRT16    KRT9    KRT40    KRT17    KRT33A    KRT33B

    Find genes that share paralogs with KRT25           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for KRT25 (see all 280)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1118467721,2
    C--38908136(+) CGTGCGT/-GTGTG 1 -- int11Minor allele frequency- -:0.50CSA 2
    rs724507281,2
    C--38912696(+) GCCTC-/AAAAAA 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1886724631,2
    --39690714(+) ACTTGA/GATTCT 1 -- ds50010--------
    rs1930448471,2
    --39690818(+) AAATAC/TTGAGT 1 -- ds50010--------
    rs1490603421,2
    --39690886(+) AAGTTA/GTTTCT 1 -- ds50010--------
    rs1858259911,2
    --39690912(+) ACCATG/TTGAAA 1 -- ds50010--------
    rs1429031971,2
    --39690924(+) AACTAC/TTTTTA 1 -- ds50010--------
    rs1136713931,2
    C,F--39691090(+) AAGCCT/ATATGA 1 -- ds50012Minor allele frequency- A:0.08CSA WA 119
    rs48901271,2
    C,F,H--39691183(+) ATAAAT/CATTCT 1 -- ds5001101Minor allele frequency- C:0.49NS NA EA PA EU CA WA CSA 6004
    rs1510870191,2
    --39691307(+) TCTAGA/GTGAAT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for KRT25 (38904273 - 38911584 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for KRT25:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv3166n71CNV Loss21882294
    nsv908227CNV Loss21882294
    nsv908226CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KRT25
    DNA2.0 Custom Variant and Variant Library Synthesis for KRT25

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus

    Find genes that share disorders with KRT25           About GenesLikeMe

    Genetic Association Database (GAD): KRT25
    Human Genome Epidemiology (HuGE) Navigator: KRT25 (1 document)

    Export disorders for KRT25 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for KRT25 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with KRT25)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. New consensus nomenclature for mammalian keratins. (PubMed id 16831889)1, 3 Schweizer J....Wright M.W. (J. Cell Biol. 2006)
    3. The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain. (PubMed id 15617563)1, 2 Rogers M.A.... Schweizer J. (Differentiation 2004)
    4. Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (J Proteomics 2012)
    5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    6. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    7. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PubMed id 17903293)4 Benjamin E.J....Vasan R.S. (BMC Med. Genet. 2007)
    8. K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), and K28 (K25irs4) represent the type I inner root sheath keratins of the human hair follicle. (PubMed id 16874310)2 Langbein L.... Schweizer J. (J. Invest. Dermatol. 2006)
    9. Comprehensive analysis of keratin gene clusters in humans and rodents. (PubMed id 15085952)1 Hesse M.... Magin T.M. (Eur. J. Cell Biol. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 147183 HGNC: 30839 AceView: KRT25A Ensembl:ENSG00000204897 euGenes: HUgn147183
    ECgene: KRT25 H-InvDB: KRT25

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for KRT25 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for KRT25 gene:
    Search GeneIP for patents involving KRT25

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for KRT25  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for KRT25  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for KRT25  
     OriGene qSTAR qPCR primer pairs in human, mouse for KRT25   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for KRT25   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for KRT25   OriGene Custom Protein Services for KRT25  

     
     
     Block miRNA regulation of human, mouse, rat KRT25 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing KRT25
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KRT25 Predesigned siRNA for gene silencing in human, mouse, rat KRT25
     QuantiFast Probe-based Assays in human, mouse, rat KRT25 QuantiTect SYBR Green Assays in human, mouse, rat KRT25
     Custom PCR Arrays for KRT25 Search Chromatin IP Primers for KRT25
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KRT25  Search GeneGlobe Interaction Network for KRT25
     Regulatory tfbs in KRT25 promoter
     GenScript Custom Purified and Recombinant Proteins Services for KRT25 GenScript cDNA clones with any tag delivered in your preferred vector for KRT25
     GenScript Custom Assay Services for KRT25 GenScript Custom overexpressing Cell Line Services for KRT25
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for KRT25 (K1C25)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     KRT25 antibodies
     KRT25 proteins
     KRT25 lysates
     Antibodies for KRT25
     See all of Abcam's Antibodies, Kits and Proteins for KRT25
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for KRT25
     Antibodies for KRT25
     ELISAs for KRT25
     CLIAs for KRT25



     Browse ESI BIO Cell Lines and PureStem Progenitors for KRT25
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KRT25
     SwitchGear 3'UTR luciferase reporter plasmids for KRT25
     SwitchGear Promoter luciferase reporter plasmids for KRT25
     Search ThermoFisher Antibodies for KRT25
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KRT25
     Browse compounds at ApexBio
     Search Addgene for plasmids for KRT25
      Search eBioscience for proteins for KRT25
      Search eBioscience for elisas for KRT25
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for KRT25
     antibodies-online antibodies for KRT25 (15 products)
     antibodies-online kits for KRT25 (10 products)
     antibodies-online peptides for KRT25
     antibodies-online proteins for KRT25 (6 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      KRT25 gene at Home site.
    Version: 3.12.248 16 Nov 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4