Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



KRT24 Gene

protein-coding   GIFtS: 48
GCID: GC17M038854

Keratin 24

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Keratin 241 2     Keratin, Type I Cytoskeletal 242
Type I Keratin-242 3     keratin-242
CK-242 3     Cytokeratin-243
K242 3     Keratin-243
KA242 3     FLJ202615
cytokeratin-242     

External Ids:    HGNC: 185271   Entrez Gene: 1926662   Ensembl: ENSG000001679167   OMIM: 6077425   UniProtKB: Q2M2I53   

Export aliases for KRT24 gene to outside databases

Previous GC identifers: GC00U991194 GC17U900029 GC17M039228 GC17M039229 GC17M036108 GC17M034648


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for KRT24 Gene:
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate
filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament.
These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells.
The type I keratin genes are clustered in a region of chromosome 17q12-q21. (provided by RefSeq, Jun 2009)

GeneCards Summary for KRT24 Gene:
KRT24 (keratin 24) is a protein-coding gene. Diseases associated with KRT24 include hereditary mucosal leukokeratosis, and hypohidrosis. GO annotations related to this gene include structural molecule activity. An important paralog of this gene is KRT34.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000017.11  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KRT24 gene promoter:
         Oct-B1   C/EBPbeta   Nkx2-5   AP-4   CUTL1   LCR-F1   RORalpha2   RORalpha1   FOXC1   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKRT24 promoter sequence
   Search Chromatin IP Primers for KRT24

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KRT24


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.2   Ensembl cytogenetic band:  17q21.2   HGNC cytogenetic band: 17q21.2

KRT24 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KRT24 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M038854:  view genomic region     (about GC identifiers)

Start:
38,854,243 bp from pter      End:
38,860,002 bp from pter
Size:
5,760 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: K1C24_HUMAN, Q2M2I5 (See protein sequence)
Recommended Name: Keratin, type I cytoskeletal 24  
Size: 525 amino acids; 55087 Da
Subunit: Heterotetramer of two type I and two type II keratins
Miscellaneous: There are two types of cytoskeletal and microfibrillar keratin, I (acidic) and II (neutral to
basic) (40-55 and 56-70 kDa, respectively)
Secondary accessions: Q9NXG7

Explore the universe of human proteins at neXtProt for KRT24: NX_Q2M2I5

Explore proteomics data for KRT24 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KRT24 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_061889.2  
    ENSEMBL proteins: 
     ENSP00000264651  

    KRT24 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for KRT24
    OriGene Protein Over-expression Lysate for KRT24
    OriGene MassSpec for KRT24
    OriGene Custom Protein Services for KRT24
    GenScript Custom Purified and Recombinant Proteins Services for KRT24
    Novus Biologicals KRT24 Protein
    Novus Biologicals KRT24 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for KRT24

    KRT24 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for KRT24
    OriGene Custom Antibody Services for KRT24
    Novus Biologicals KRT24 Antibodies
    Search for Antibodies for KRT24 at Abcam
    Cloud-Clone Corp. Antibodies for KRT24
    Search ThermoFisher Antibodies for KRT24
    LSBio Antibodies in human, mouse, rat for KRT24

    KRT24 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for KRT24
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for KRT24
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for KRT24
    Cloud-Clone Corp. CLIAs for KRT24


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    IFF1: Intermediate filaments type I, keratins (acidic)

    4 InterPro protein domains:
     IPR009053 Prefoldin
     IPR018039 Intermediate_filament_CS
     IPR001664 IF
     IPR002957 Keratin_I

    Graphical View of Domain Structure for InterPro Entry Q2M2I5

    ProtoNet protein and cluster: Q2M2I5

    2 Blocks protein domains:
    IPB001664 Intermediate filament protein
    IPB002957 Type I keratin signature


    UniProtKB/Swiss-Prot: K1C24_HUMAN, Q2M2I5
    Similarity: Belongs to the intermediate filament family


    KRT24 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: K1C24_HUMAN, Q2M2I5
    Induction: Up-regulated in the mucosa of patients suffering of colorectal cancer

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005198structural molecule activity IEA--
         
    KRT24 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for KRT24:
     Increased S DNA content  Metaphase cells 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KRT24
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for KRT24

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KRT24
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KRT24

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat KRT24 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate KRT24
    SwitchGear 3'UTR luciferase reporter plasmidKRT24 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for KRT24
    Predesigned siRNA for gene silencing in human, mouse, rat KRT24

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for KRT24

    Clone
    Products:
         
    OriGene clones in human, mouse for KRT24 (see all 5)
    OriGene ORF clones in mouse, rat for KRT24
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KRT24 (NM_019016)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KRT24
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KRT24

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for KRT24
    Browse ESI BIO Cell Lines and PureStem Progenitors for KRT24 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KRT24


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton4
    cytosol3
    nucleus3

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005882intermediate filament IEA--
    GO:0045111intermediate filament cytoskeleton IDA--

    KRT24 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KRT24
    Interactions:

        Search GeneGlobe Interaction Network for KRT24

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    Selected Interacting proteins for KRT24 (Q2M2I53 ENSP000002646514) via UniProtKB, MINT, STRING, and/or I2D (see all 41)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAP1LC3BQ9GZQ83, ENSP000002686074I2D: score=1 STRING: ENSP00000268607
    GABARAPL1Q9H0R83I2D: score=2 
    MAP1LC3AQ9H4923I2D: score=2 
    AMBRA1Q9C0C73I2D: score=1 
    ATG10Q9H0Y03I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    KRT24 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KRT24 (K1C24)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for KRT24 gene: 
    NM_019016.2  

    Unigene Cluster for KRT24:

    Keratin 24
    Hs.87383  [show with all ESTs]
    Unigene Representative Sequence: AK000268
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000264651(uc002hvd.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat KRT24 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate KRT24
    SwitchGear 3'UTR luciferase reporter plasmidKRT24 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for KRT24
    Predesigned siRNA for gene silencing in human, mouse, rat KRT24
    Clone
    Products:
         
    OriGene clones in human, mouse for KRT24 (see all 5)
    OriGene ORF clones in mouse, rat for KRT24
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KRT24 (NM_019016)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KRT24
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KRT24
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for KRT24
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KRT24
      QuantiTect SYBR Green Assays in human, mouse, rat KRT24
      QuantiFast Probe-based Assays in human, mouse, rat KRT24

    Additional mRNA sequence: 

    AK000268.1 BC111964.1 BC111968.1 

    3 DOTS entries:

    DT.40117810  DT.100760343  DT.92419569 

    Selected AceView cDNA sequences (see all 25):

    BM726381 AA234933 BU685476 CR607026 BM681555 AA234932 CR609628 AI373805 
    AI128031 BV184034 BX339197 BX390566 NM_019016 AL577554 BX100314 BX399643 
    AK000268 AA889092 AW366801 BE181957 BE181968 AI373145 BE182037 AA422013 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    KRT24 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGATCCAGGG
    KRT24 Expression
    About this image


    KRT24 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Neurons
             nGnG Amacrine Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)    fully expand to see all 2 entries
             nGnG Amacrine Cells Inner Nuclear Layer
     
     NULL (Uncategorized)
             Vascular endothelial growth factor-induced embryoid bodies
     
     Ovary (Reproductive System)
    KRT24 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KRT24 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.87383

    UniProtKB/Swiss-Prot: K1C24_HUMAN, Q2M2I5
    Tissue specificity: Highly expressed in keratinocytes, placenta, colon and spleen. Expressed at lower level in
    thymus and testis

        Custom PCR Arrays for KRT24
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for KRT24
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KRT24
    QuantiTect SYBR Green Assays in human, mouse, rat KRT24
    QuantiFast Probe-based Assays in human, mouse, rat KRT24
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KRT24

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for KRT24 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Krt241 , 5 keratin 241, 5 79.59(n)1
    74.39(a)1
      11 (62.92 cM)5
    757061  NM_029393.11  NP_083669.11 
     992799595 
    lizard
    (Anolis carolinensis)
    Reptilia KRT246
    keratin 24
    61(a)
    1 ↔ 1
    6(70390670-70404326)
    African clawed frog
    (Xenopus laevis)
    Amphibia AB086829.12   -- 74.97(n)    AB086829.1 


    ENSEMBL Gene Tree for KRT24 (if available)
    TreeFam Gene Tree for KRT24 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for KRT24 gene
    KRT342  KRT172  KRT162  KRT312  KRT252  KRT392  KRT402  KRT202  
    KRT372  KRT272  KRT322  KRT382  KRT362  KRT192  KRT282  KRT142  
    KRT132  KRT262  KRT102  KRT122  KRT352  KRT152  KRT33B2  KRT92  
    KRT33A2  
    Selected SIMAP similar genes for KRT24 using alignment to 1 protein entry:     K1C24_HUMAN(see all similar genes):
    KRT19    keratin    KRT13    KRT10    KRT15    KRT12
    KRT25    KRT27    KRT31    KRT33A    JUP    KRT16
    KRT35    KRT26    KRT32    KRT40    KRT14    KRT28

    KRT24 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for KRT24
    PGOHUM00000237070


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for KRT24 (see all 294)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs362056051,2
    C--34652318(+) TCTAG-/TATATATATATATAT
    ATATATATATATATATA
    TATAT
    1 -- int10--------
    rs1112296681,2
    C,F--38853817(+) GACGCT/GCTTGG 1 -- int11Minor allele frequency- G:0.00CSA 1
    rs1897497781,2
    --38857987(+) TATATA/TTATAT 1 -- int10--------
    rs1856153691,2
    --39640797(+) CCCTGA/CATTAT 1 -- int10--------
    rs781156461,2
    C,F--39641008(+) CTAGCC/TGTCTT 1 -- int11Minor allele frequency- T:0.03NA 120
    rs354017031,2
    C,F--39641058(+) GTGTGT/GCATTT 1 -- int15Minor allele frequency- G:0.07NA CSA WA 126
    rs1904228201,2
    --39641075(+) AACTCG/TCTCAG 1 -- int10--------
    rs1821820461,2
    --39641172(+) AAATAA/CTTTTT 1 -- int10--------
    rs359077081,2
    C,F--39641302(+) GAAAAG/ATTGGC 1 -- ut315Minor allele frequency- A:0.10NA WA CSA 126
    rs350782631,2
    C,F--39641323(+) TTTCTG/AGACTG 1 -- ut316Minor allele frequency- A:0.10NA WA CSA 128

    HapMap Linkage Disequilibrium report for KRT24 (38854243 - 38860002 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for KRT24:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv908225CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KRT24
    DNA2.0 Custom Variant and Variant Library Synthesis for KRT24

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 607742    OMIM disorders: --

    8 diseases for KRT24:    
    About MalaCards
    hereditary mucosal leukokeratosis    hypohidrosis    palmoplantar keratosis    keratosis
    tonsillitis    colorectal cancer    esophagitis    endotheliitis

    1 disease from the University of Copenhagen DISEASES database for KRT24:
    Hypohidrosis

    KRT24 for disorders           About GeneDecksing


    Export disorders for KRT24 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for KRT24 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with KRT24)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Refined mapping of Naegeli-Franceschetti-Jadassohn syndrome to a 6 cM interval on chromosome 17q11.2-q21 and investigation of candidate genes. (PubMed id 12230514)1, 2, 9 Sprecher E.... Richard G. (J. Invest. Dermatol. 2002)
    2. A susceptibility gene set for early onset colorectal cancer that integrates diverse signaling pathways: implication for tumorigenesis. (PubMed id 17317818)1, 2 Hong Y.... Cheah P.Y. (Clin. Cancer Res. 2007)
    3. New consensus nomenclature for mammalian keratins. (PubMed id 16831889)1, 3 Schweizer J....Wright M.W. (J. Cell Biol. 2006)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    5. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    6. Charting the molecular network of the drug target Bcr-Abl. (PubMed id 19380743)1 Brehme M....Superti-Furga G. (Proc. Natl. Acad. Sci. U.S.A. 2009)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 192666 HGNC: 18527 AceView: KRT24 Ensembl:ENSG00000167916 euGenes: HUgn192666
    ECgene: KRT24 H-InvDB: KRT24

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for KRT24 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for KRT24 gene:
    Search GeneIP for patents involving KRT24

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for KRT24   OriGene RNAi products in human, mouse, rat for KRT24  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for KRT24  
     OriGene MassSpec something-or-other for KRT24   OriGene clones in human, mouse for KRT24  
     OriGene qSTAR qPCR primer pairs in human, mouse for KRT24   OriGene Purified Protein for KRT24  
     OriGene ORF clones in mouse, rat for KRT24   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for KRT24   OriGene Custom Protein Services for KRT24  

     
     
     Block miRNA regulation of human, mouse, rat KRT24 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing KRT24
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KRT24 Predesigned siRNA for gene silencing in human, mouse, rat KRT24
     QuantiFast Probe-based Assays in human, mouse, rat KRT24 QuantiTect SYBR Green Assays in human, mouse, rat KRT24
     Custom PCR Arrays for KRT24 Search Chromatin IP Primers for KRT24
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KRT24  Search GeneGlobe Interaction Network for KRT24
     Regulatory tfbs in KRT24 promoter
     GenScript Custom Purified and Recombinant Proteins Services for KRT24 GenScript cDNA clones with any tag delivered in your preferred vector for KRT24
     GenScript Custom Assay Services for KRT24 GenScript Custom overexpressing Cell Line Services for KRT24
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for KRT24 (K1C24)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     KRT24 antibodies
     KRT24 proteins
     KRT24 lysates
     Search for Antibodies for KRT24 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for KRT24
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for KRT24
     Antibodies for KRT24
     ELISAs for KRT24
     CLIAs for KRT24



     Browse ESI BIO Cell Lines and PureStem Progenitors for KRT24
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KRT24
     SwitchGear 3'UTR luciferase reporter plasmids for KRT24
     SwitchGear Promoter luciferase reporter plasmids for KRT24
     Search ThermoFisher Antibodies for KRT24
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KRT24
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KRT24
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for KRT24
     LSBio Antibodies in human, mouse, rat for KRT24
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      KRT24 gene at Home site.
    Version: 3.12.166 28 Aug 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4