Aliases for KRT10 Gene
External Ids for KRT10 Gene
Previous Symbols for KRT10 Gene
This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq, Jul 2008]
GeneCards Summary for KRT10 Gene
KRT10 (Keratin 10, Type I) is a Protein Coding gene. Diseases associated with KRT10 include epidermolytic hyperkeratosis and ichthyosis with confetti. Among its related pathways are Staphylococcus aureus infection and Cytoskeletal Signaling. GO annotations related to this gene include structural constituent of epidermis. An important paralog of this gene is KRT34.