KRI1 Gene
protein-coding GIFtS: 46
GCID: GC19M010663
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KRI1 homolog (S. cerevisiae)
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Aliases
for KRI1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| KRI1 Homolog (S. Cerevisiae)1 2 | | FLJ129491 | | Protein KRI1 Homolog2 |
Export aliases for KRI1 gene to outside databasesPrevious GC identifers: GC19M010525 GC19M010241 |
Summaries
for KRI1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KRI1:
This gene overlaps with the gene for cysteine endopeptidase AUT-like 4 in a head-to-tail orientation. (provided byRefSeq, Jul 2008)
|
Genomic Views
for KRI1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KRI1 gene promoter:
p53 NF-YA LCR-F1 NF-YB CBF-A CBF-B CP1A NF-Y CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for KRI1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KRI1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.2 Ensembl cytogenetic band: 19p13.2 HGNC cytogenetic band: 19p13.2KRI1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M010663: view genomic region
(about GC identifiers)
Start:
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10,663,761 bp from pter |
End:
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10,676,713 bp from pter |
Size:
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12,953 bases |
Orientation:
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minus strand |
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Proteins
for KRI1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KRI1_HUMAN, Q8N9T8 (See
protein sequence)Recommended Name: Protein KRI1 homolog Size: 709 amino acids; 83252 Da
Sequence caution: Sequence=BAB15278.1; Type=Erroneous initiation;
Secondary accessions: Q2M1R5 Q2M1R7 Q7L5J7 Q96G92 Q9BU50 Q9H6I1 Q9H978Alternative splicing: 2 isoforms: Q8N9T8-1 Q8N9T8-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for KRI1: NX_Q8N9T8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N9T8
KRI1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_075384.3
ENSEMBL proteins: ENSP00000320917 ENSP00000355366 ENSP00000445789 ENSP00000412919 ENSP00000438000 ENSP00000442277 ENSP00000442213
Human Recombinant Protein Products:
KRI1 Antibody Products:
Assay Products for KRI1: |
Protein
Domains /
Families
for KRI1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KRI1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8N9T8ProtoNet protein and cluster: Q8N9T8 UniProtKB/Swiss-Prot: KRI1_HUMAN, Q8N9T8Similarity: Belongs to the KRI1 family |
Function
for KRI1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KRI1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KRI1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: KRI1 (NM_023008) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KRI1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KRI1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KRI1 |
|
Pathways & Interactions
for KRI1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KRI1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 13)
5/16 Interacting proteins for KRI1 (Q8N9T82, 3 ENSP000003209174) via UniProtKB, MINT, STRING, and/or I2D (see all 16)About this table
|
Drugs & Compounds
for KRI1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KRI1
Search CenterWatch for drugs/clinical trials and news about KRI1
|
Transcripts
for KRI1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KRI1 gene (2 alternative transcripts): NM_178159.1 NM_023008.3 Unigene Cluster for KRI1: KRI1 homolog (S. cerevisiae) Hs.709967 [show with all ESTs]Unigene Representative Sequence: NM_02300814 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000536689 ENST00000312962(uc002mow.1 uc002mox.1 uc002moy.1)
ENST00000537363 ENST00000478863 ENST00000361821 ENST00000537433 ENST00000543842
ENST00000539027 ENST00000536714 ENST00000432197 ENST00000543682 ENST00000546063
ENST00000537964 ENST00000544397
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KRI1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KRI1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KRI1 (NM_023008) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KRI1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KRI1 |
Additional cDNA sequence: AK023011.1 AK025907.1 AK300780.1 AK300850.1 BC002890.2 BC009876.2 BC112249.1 BC112251.1 BC143770.1 19 DOTS entries: DT.97858898 DT.100038929 DT.445212 DT.121504195 DT.100038930 DT.75177661 DT.100791486 DT.121504207 DT.100791484 DT.121504217 DT.100791485 DT.100791487 DT.121504178 DT.121504183 DT.121504193 DT.121504212 DT.91700605 DT.91752123 DT.91752125 24/214 AceView cDNA sequences (see all 214): BU157452 BU161157 BM833746 BQ003121 BM452480 AA764729 AA151699 BG831128 AI818910 NM_178159 BU739852 AW615635 BU944168 NM_023008 AI091723 BQ052530 AL833189 BE408531 BQ678576 BU538709 BF513460 CB123919 BQ054357 BE797423
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for KRI1 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 |
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| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for KRI1
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Expression
for KRI1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KRI1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGTTTGAGGC
About this image
See KRI1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KRI1
SOURCE GeneReport for Unigene cluster: Hs.709967
SABiosciences Custom PCR Arrays for KRI1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KRI1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KRI1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KRI1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KRI1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KRI1 |
Orthologs
for KRI1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for KRI1 gene from 9/30 species (see all 30) About this table
ENSEMBL Gene Tree for KRI1 (if available)
TreeFam Gene Tree for KRI1 (if available) |
Paralogs
for KRI1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for KRI1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KRI1 (10663761 - 10676713 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for KRI1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KRI1 |
|
Disorders
/ Diseases
for KRI1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KRI1 for disorders About GeneDecksing
2  diseases for KRI1: About MalaCardsdental pulp necrosis malaria
1 disease from the University of Copenhagen DISEASES database for KRI1:Dental pulp necrosis Human Genome Epidemiology (HuGE) Navigator: KRI1 (1 document)
Export disorders for KRI1 gene to outside databases
|
Publications
for KRI1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KRI1 gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with KRI1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis. (PubMed id 12878157)1, 3 Imabayashi H.... Umezawa A. (2003)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)1 Emanuele M.J....Elledge S.J. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- System-wide changes to SUMO modifications in response to heat shock. (PubMed id 19471022)1 Golebiowski F....Hay R.T. (2009)
|
External Searches for KRI1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KRI1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KRI1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KRI1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KRI1 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for KRI1 gene:
Search GeneIP for patents involving KRI1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KRI1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KRI1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KRI1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KRI1 | | | OriGene Protein Over-expression Lysate for KRI1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KRI1 | | OriGene 3'-UTR Clone for KRI1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KRI1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KRI1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KRI1 | | OriGene Custom Protein Services for KRI1 | | | OriGene Custom Immunoassay Development | | |
| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KRI1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KRI1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KRI1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KRI1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KRI1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KRI1 |
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| | | | Search Tocris compounds for KRI1 |
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 | | | KRI1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KRI1 |
|  |  |  | | | | ThermoFisher Antibodies for KRI1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KRI1 |
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