KREMEN1 Gene
protein-coding GIFtS: 55
GCID: GC22P029469
|
|
kringle containing transmembrane protein 1(Previous name: kringle containing transmembrane protein )
(Previous symbol: KREMEN)
| |
Aliases
for KREMEN1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Kringle Containing Transmembrane Protein 11 2 | | Kringle Containing Transmembrane Protein1 | | KRM11 2 3 5 | | Kremen Protein 12 | | KREMEN1 2 3 | | Kringle-Coding Gene Marking The Eye And The Nose2 | | Dickkopf Receptor2 3 | | KREMEM15 | | Kringle Domain-Containing Transmembrane Protein 12 3 | | EC 3.4.218 | | Kringle-Containing Protein Marking The Eye And The Nose2 3 | | |
Export aliases for KREMEN1 gene to outside databasesPrevious GC identifers: GC22P026166 GC22P027793 GC22P012433 |
Summaries
for KREMEN1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KREMEN1:
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates withDKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex thatmodulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellularkringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observedfor this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: KREM1_HUMAN, Q96MU8Function: Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity)
Gene Wiki entry for KREMEN1
|
Genomic Views
for KREMEN1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KREMEN1 gene promoter:
Pbx1a SREBP-1c Lmo2 CUTL1 SREBP-1b FAC1 Nkx6-1 FOXC1 SREBP-1a ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for KREMEN1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KREMEN1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q12.1 Ensembl cytogenetic band: 22q12.1 HGNC cytogenetic band: 22q12.1KREMEN1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22P029469: view genomic region
(about GC identifiers)
Start:
|
29,469,066 bp from pter |
End:
|
29,564,321 bp from pter |
Size:
|
95,256 bases |
Orientation:
|
plus strand |
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Proteins
for KREMEN1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KREM1_HUMAN, Q96MU8 (See
protein sequence)Recommended Name: Kremen protein 1 precursor Size: 473 amino acids; 51744 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)
Secondary accessions: B0QY46 B0QY47 B1AJR5 Q5TIB9 Q6P3X6 Q9BY70 Q9UGS5 Q9UGU1Alternative splicing: 3 isoforms: Q96MU8-1 Q96MU8-2 Q96MU8-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for KREMEN1: NX_Q96MU8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96MU8
2 DME Specific Peptides for KREMEN1 (Q96MU8)
KREMEN1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001034659.2 NP_114434.3
ENSEMBL proteins: ENSP00000383189 ENSP00000331242 ENSP00000385431 ENSP00000388228 ENSP00000383192
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
KREMEN1 for ontologies About GeneDecksing
KREMEN1 Antibody Products:
Assay Products for KREMEN1: |
Protein
Domains /
Families
for KREMEN1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KREMEN1 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q96MU8ProtoNet protein and cluster: Q96MU8 3 Blocks protein families: IPB000001 Kringle IPB000859 CUB domain IPB002889 Carbohydrate-binding WSC
UniProtKB/Swiss-Prot: KREM1_HUMAN, Q96MU8Similarity: Contains 1 CUB domainSimilarity: Contains 1 kringle domainSimilarity: Contains 1 WSC domain |
Function
for KREMEN1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KREM1_HUMAN, Q96MU8Function: Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity)Enzyme Number (IUBMB): EC 3.4.212
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KREMEN1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KREMEN1 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for KREMEN1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KREMEN1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KREMEN1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
KREMEN1 for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for KREMEN1:
Animal Models:
Mouse knock-out Kremen1tm1Dgen for KREMEN1
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Kremen1):
KREMEN1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for KREMEN1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Wnt signaling network | | | 2 | WNT Signaling | |
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for KREMEN1
1  BioSystems Pathway for KREMEN1
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for KREMEN1
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
3 Interacting proteins for KREMEN1 (Q96MU83 ENSP000003312424) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
KREMEN1 for ontologies About GeneDecksing
|
Drugs & Compounds
for KREMEN1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KREMEN1
Search CenterWatch for drugs/clinical trials and news about KREMEN1 / KREM1
|
Transcripts
for KREMEN1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KREMEN1 gene (3 alternative transcripts): NM_001039570.2 NM_032045.4 NM_153379.2 Unigene Cluster for KREMEN1: Kringle containing transmembrane protein 1 Hs.229335 [show with all ESTs]Unigene Representative Sequence: NM_0010395707 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000400335(uc003ael.3) ENST00000327813(uc011akm.1) ENST00000407188
ENST00000453585 ENST00000474001 ENST00000479755 ENST00000400338(uc011akn.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KREMEN1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KREMEN1 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): KREMEN1 (NM_032045) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KREMEN1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KREMEN1 |
Additional cDNA sequence: AB059618.1 AK056425.1 AK172861.1 BC063787.1 8 DOTS entries: DT.86855454 DT.86859493 DT.102828624 DT.100648274 DT.308144 DT.100653664 DT.100668388 DT.91793171 24/112 AceView cDNA sequences (see all 112): BI791967 BM794636 BF376901 BM798726 BM468254 NM_153379 BU101656 AB059618 BC063787 CD724015 BX430917 CD633575 AA235330 NM_032045 BM796358 BG743250 BM857328 BX095788 BX477602 AI049755 BX451207 BF057751 BF221745 AI085656
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for KREMEN1 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for KREMEN1
|
Expression
for KREMEN1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KREMEN1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATTTTAAAA
About this image
See KREMEN1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KREMEN1
SOURCE GeneReport for Unigene cluster: Hs.229335
SABiosciences Expression via Pathway-Focused PCR Array including KREMEN1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KREMEN1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KREMEN1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KREMEN1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KREMEN1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KREMEN1 |
Orthologs
for KREMEN1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for KREMEN1 gene from 3/11 species (see all 11) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
KREMEN11 |
kringle containing transmembrane protein 1 |
70.57(n)
73.87(a) |
|
416920 XM_415211.3 XP_415211.3 |
African clawed frog
(Xenopus laevis) |
Amphibia |
kremen2 |
kremen protein |
75.71(n) |
|
AB070851.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
kremen11 |
kringle containing transmembrane protein 1 |
61.39(n)
60.86(a) |
|
100141352 NM_001114917.1 NP_001108389.1 |
ENSEMBL Gene Tree for KREMEN1 (if available)
TreeFam Gene Tree for KREMEN1 (if available) |
Paralogs
for KREMEN1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KREMEN1 gene
- KREMEN22 PLAT2 PLG2 HGFAC2 LPA2 PLAU2 HABP22 MST12
- F122 MST1L2 HGF2
3 SIMAP similar genes for KREMEN1 using alignment to 3 protein entries: KREM1_HUMAN (see all proteins):KREMEN2 APOA LPAL2
KREMEN1 for paralogs About GeneDecksing
|
Genomic Variants
for KREMEN1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KREMEN1 (29469066 - 29564321 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 15 variations for KREMEN1
13 CNVs: 91020 79538 79542 91017 79539 79543 91018 91019 91016 79540 50847 10622 79541
2 Indels: 73809 46218 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KREMEN1 |
|
Disorders
/ Diseases
for KREMEN1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KREMEN1 for disorders About GeneDecksing
OMIM gene information: 609898
OMIM disorders: --
5  diseases for KREMEN1: About MalaCardssost-related sclerosing bone dysplasia osteoporosis-pseudoglioma syndrome hyperostosis osteoporosis
myeloma
1 disease from the University of Copenhagen DISEASES database for KREMEN1:SOST-related sclerosing bone dysplasia Human Genome Epidemiology (HuGE) Navigator: KREMEN1 (6 documents)
Export disorders for KREMEN1 gene to outside databases
|
Publications
for KREMEN1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KREMEN1 gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with KREMEN1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Molecular cloning and characterization of Kremen, a novel kringle-containing transmembrane protein. (PubMed id 11267660)1, 3 Nakamura T....Nakamura T. (2001)
- The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Genetic association study of KREMEN1 and DKK1 and sch izophrenia in a Japanese population. (PubMed id 20153141)1 Aleksic B....Ozaki N. (2010)
- Maternal genes and facial clefts in offspring: a comp rehensive search for genetic associations in two population-based cleft studies from Scandinavia. (PubMed id 20634891)1 Jugessur A....Murray J.C. (2010)
- Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distr ibution. (PubMed id 20935629)1 Heid I.M....Lindgren C.M. (2010)
- Differential expression of DKK-1 binding receptors on stromal cells and myeloma cells results in their distinct response to secreted DKK-1 in myeloma. (PubMed id 20846389)1 Dun X....Hou J. (2010)
- High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PubMed id 19453261)1 Yerges L.M....Zmuda J.M. (2009)
|
External Searches for KREMEN1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KREMEN1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KREMEN1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KREMEN1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KREMEN1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for KREMEN1 gene:
Search GeneIP for patents involving KREMEN1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KREMEN1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KREMEN1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KREMEN1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KREMEN1 | | | OriGene Protein Over-expression Lysate for KREMEN1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KREMEN1 | | OriGene 3'-UTR Clone for KREMEN1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KREMEN1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KREMEN1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KREMEN1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KREMEN1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KREMEN1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KREMEN1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KREMEN1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KREMEN1 |
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| |  |  |  |  | | | | |
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 | | | KREMEN1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KREMEN1 |
|  |  |  | | | | ThermoFisher Antibodies for KREMEN1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KREMEN1 |
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