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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KPNA7 Gene

protein-coding   GIFtS: 44
GCID: GC07M098771

Karyopherin Alpha 7 (Importin Alpha 8)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Karyopherin Alpha 7 (Importin Alpha 8)1 2
Karyopherin Subunit Alpha-72 3
Importin Subunit Alpha-82
Karyopherin 72

External Ids:    HGNC: 218391   Entrez Gene: 4025692   Ensembl: ENSG000001854677   OMIM: 6141075   UniProtKB: A9QM743   

Export aliases for KPNA7 gene to outside databases

Previous GC identifers: GC07M098614 GC07M093403


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for KPNA7 Gene: 
KPNA7 (karyopherin alpha 7 (importin alpha 8)) is a protein-coding gene. Diseases associated with KPNA7 include ulcerative colitis, and influenza, and among its related super-pathways are Interferon Signaling and Adaptive Immune System. GO annotations related to this gene include protein transporter activity. An important paralog of this gene is KPNA3.

UniProtKB/Swiss-Prot: IMA8_HUMAN, A9QM74
Function: Functions in nuclear protein import (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007933.15  NT_079595.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KPNA7 gene promoter:
         AhR   SRF   POU2F1   SRF (504 AA)   POU2F1a   Arnt   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for KPNA7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KPNA7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22.1   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22.1

KPNA7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KPNA7 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M098771:  view genomic region     (about GC identifiers)

Start:
98,771,197 bp from pter      End:
98,805,129 bp from pter
Size:
33,933 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 98,127,179-98,161,076     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: IMA8_HUMAN, A9QM74 (See protein sequence)
Recommended Name: Importin subunit alpha-8  
Size: 516 amino acids; 56938 Da
Subunit: Binds very efficiently to importin subunit beta-1/KPNB1 via the IBB domain; this complex dissociates in
the presence of RAN-GTP. Shows a limited binding to the RB1 nuclear localization signal (NLS), but not to the
SV40, nor NPM1 NLSs
Subcellular location: Nucleus
Sequence caution: Sequence=EAL23884.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A4D277

Explore the universe of human proteins at neXtProt for KPNA7: NX_A9QM74

Explore proteomics data for KPNA7 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_A9QM74

  • KPNA7 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KPNA7 Protein Expression
    REFSEQ proteins: NP_001139187.1  
    ENSEMBL proteins: 
     ENSP00000330878  
    Reactome Protein details: A9QM74
    Human Recombinant Protein Products for KPNA7: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for KPNA7
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for KPNA7
    GenScript Custom Purified and Recombinant Proteins Services for KPNA7
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005654nucleoplasm TAS--
    GO:0005737cytoplasm ----
    GO:0005829cytosol TAS--

    KPNA7 for ontologies           About GeneDecksing



    KPNA7 Antibody Products: 
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    Assay Products for KPNA7: 
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    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ARMC: Armadillo repeat containing
    IPO: Importins

    5 InterPro protein domains:
     IPR011989 ARM-like
     IPR000225 Armadillo
     IPR024931 Importing_su_alpha
     IPR002652 Importin-a_IBB
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry A9QM74

    ProtoNet protein and cluster: A9QM74

    UniProtKB/Swiss-Prot: IMA8_HUMAN, A9QM74
    Similarity: Belongs to the importin alpha family
    Similarity: Contains 8 ARM repeats
    Similarity: Contains 1 IBB domain


    KPNA7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IMA8_HUMAN, A9QM74
    Function: Functions in nuclear protein import (By similarity)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding ----
    GO:0008565protein transporter activity IEA--
         
    KPNA7 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for KPNA7:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for KPNA7 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for KPNA7

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KPNA7 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KPNA7 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KPNA7
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate KPNA7
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for KPNA7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KPNA7

    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of KPNA7

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
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    OriGene ORF clones in mouse, rat for KPNA7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KPNA7 (NM_001145715)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KPNA7
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KPNA7
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                         Customized lentivirus expression plasmids for stable overexpression of KPNA7 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KPNA7


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for KPNA7 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Interferon Signaling
    Interferon Signaling0.61
    Antiviral mechanism by IFN-stimulated genes0.42
    Cytokine Signaling in Immune system0.61
    ISG15 antiviral mechanism0.42
    2Immune System
    Immune System0.56

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5        Reactome Pathways for KPNA7
        Antiviral mechanism by IFN-stimulated genes
    Cytokine Signaling in Immune system
    Interferon Signaling
    ISG15 antiviral mechanism
    Immune System



    KPNA7 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KPNA7

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for KPNA7 (A9QM743 ENSP000003308784) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H1CP164033, ENSP000003395664I2D: score=1 STRING: ENSP00000339566
    SPOPENSP000002403274STRING: ENSP00000240327
    RAC1ENSP000003484614STRING: ENSP00000348461
    CSE1LENSP000002629824STRING: ENSP00000262982
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006606protein import into nucleus IEA--
    GO:0019221cytokine-mediated signaling pathway TAS--

    KPNA7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KPNA7 (IMA8)

    Search CenterWatch for drugs/clinical trials and news about KPNA7 / IMA8

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KPNA7 gene: 
    NM_001145715.1  

    Unigene Cluster for KPNA7:

    Karyopherin alpha 7 (importin alpha 8)
    Hs.253050  [show with all ESTs]
    Unigene Representative Sequence: NM_001145715
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000327442(uc010lft.2)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KPNA7
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate KPNA7
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for KPNA7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KPNA7
    Clone
    Products:
         
    OriGene clones in human, mouse for KPNA7 (see all 6)
    OriGene ORF clones in mouse, rat for KPNA7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KPNA7 (NM_001145715)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KPNA7
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KPNA7
    Sirion Biotech Customized lentivirus for stable overexpression of KPNA7 
                         Customized lentivirus expression plasmids for stable overexpression of KPNA7 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for KPNA7
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KPNA7
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KPNA7
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KPNA7

    Additional mRNA sequence: EU126604.1 

    2 DOTS entries:

    DT.102820269  DT.121125735 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KPNA7 expression in normal human tissues (normalized intensities)      KPNA7 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATCAGCTGA
    KPNA7 Expression
    About this image


    KPNA7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Ovary (Reproductive System)
             Secondary follicles

    See KPNA7 Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.253050
        SABiosciences Custom PCR Arrays for KPNA7
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for KPNA7
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KPNA7
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KPNA7
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KPNA7
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KPNA7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for KPNA7 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kpna71 , 5 karyopherin alpha 7 (importin alpha 8)1, 5 72.34(n)1
    63.32(a)1
      5 (84.91 cM)5
    3816861  NM_001013774.21  NP_001013796.21 
     1449835195 
    chicken
    (Gallus gallus)
    Aves KPNA71 karyopherin alpha 7 (importin alpha 8) 65.29(n)
    61.54(a)
      416488  XM_414795.3  XP_414795.3 
    lizard
    (Anolis carolinensis)
    Reptilia KPNA76
    Uncharacterized protein
    49(a)
    1 ↔ 1
    3(18178330-18179312)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:558771 zgc:55877 57.77(n)
    52.77(a)
      406343  NM_213070.1  NP_998235.1 
    worm
    (Caenorhabditis elegans)
    Secernentea ima-26
    Importin subunit alpha-2
    33(a)
    1 → many
    I(6315231-6317267)


    ENSEMBL Gene Tree for KPNA7 (if available)
    TreeFam Gene Tree for KPNA7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KPNA7 gene
    KPNA32  SPAG62  KPNA52  KPNA22  KPNA42  KPNA62  KPNA12  
    5 SIMAP similar genes for KPNA7 using alignment to 1 protein entry:     IMA8_HUMAN:
    KPNA2    KPNA3    KPNA4    KPNA1    KPNA6

    KPNA7 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for KPNA7
    PGOHUM00000235279


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1008 SNPs in KPNA7 are shown (see all 1008)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs609701411,2
    C--93407853(+) AAAAA-/AA    
       
    /AAAA
    GTCAC
    1 -- int11NA 2
    rs2008052771,2
    --98770702(+) AAAAA-/GAAAAA 1 -- int10--------
    rs1913453741,2
    --98770703(+) AAAAAA/GAAAAG 1 -- int10--------
    rs2006662111,2
    --98770703(+) AAAAA-/GAAAAG 1 -- int10--------
    rs1838830661,2
    --98770704(+) AAAAAA/GAAAGA 1 -- int10--------
    rs1869446891,2
    --98770728(+) TGTCCA/GGATAA 1 -- int10--------
    rs1918456061,2
    --98770794(+) CAATTA/GCTAAA 1 -- int10--------
    rs1852690021,2
    --98770873(+) CAATGA/GCTCCA 1 -- int10--------
    rs1899991351,2
    --98771004(+) AGAGAC/TGGAGT 1 -- int10--------
    rs1447622821,2
    C--98771021(+) GTGTTA/GGCCAG 1 -- int10--------

    HapMap Linkage Disequilibrium report for KPNA7 (98771197 - 98805129 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for KPNA7:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2734881CNV Deletion23290073
    esv2734879CNV Deletion23290073
    esv2734880CNV Deletion23290073
    esv2734876CNV Deletion23290073
    esv2660936CNV Deletion23128226
    esv2734877CNV Deletion23290073
    esv2623610CNV Deletion19546169
    esv2734878CNV Deletion23290073
    nsv509216CNV Insertion20534489
    dgv828n27CNV Loss19166990

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing KPNA7
    DNA2.0 Custom Variant and Variant Library Synthesis for KPNA7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614107    OMIM disorders: --

    2 diseases for KPNA7:    About MalaCards
    ulcerative colitis    influenza


    KPNA7 for disorders           About GeneDecksing

    Genetic Association Database (GAD): KPNA7

    Export disorders for KPNA7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KPNA7 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with KPNA7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL). (PubMed id 20228798)1, 4 Franke A....Vatn M.H. (2010)
    2. Karyopherin alpha7 (KPNA7), a divergent member of the importin alpha family of nuclear import receptors. (PubMed id 20701745)1, 2 Kelley J.B....Paschal B.M. (2010)
    3. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    4. Isolation and characterization of a novel H1.2 complex that acts as a repressor of p53-mediated transcription. (PubMed id 18258596)1 Kim K....An W. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 402569 HGNC: 21839 Ensembl:ENSG00000185467 euGenes: HUgn402569 ECgene: KPNA7
    H-InvDB: KPNA7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KPNA7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KPNA7 gene:
    Search GeneIP for patents involving KPNA7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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     inGenious Targeting Laboratory - Custom generated mouse model solutions for KPNA7
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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