KPNA6 Gene
protein-coding GIFtS: 56
GCID: GC01P032573
|
|
karyopherin alpha 6 (importin alpha 7)
| |
Aliases
for KPNA6 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Karyopherin Alpha 6 (Importin Alpha 7)1 2 | | MGC179181 | | IPOA71 2 3 | | Importin Alpha 7 Subunit2 | | KPNA71 2 | | Importin Subunit Alpha-72 | | Karyopherin Subunit Alpha-62 3 | | Importin-Alpha-S21 | | FLJ112491 | | |
Export aliases for KPNA6 gene to outside databasesPrevious GC identifers: GC01P032388 GC01P031561 GC01P032000 GC01P032076 GC01P032242 GC01P032346 GC01P030689 |
Summaries
for KPNA6 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KPNA6:
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexesembedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires theNLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alphabinds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of thenuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complexmoves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm withits passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of theimportin alpha family. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: IMA7_HUMAN, O60684Function: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically anddirectly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex tothe nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex issubsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic sideof the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exportedfrom the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclearimport is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between thecytoplasm and nucleus
Gene Wiki entry for KPNA6
|
Genomic Views
for KPNA6 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KPNA6 gene promoter:
SRF RFX1 NF-1 SRF (504 AA) MIF-1 MEF-2A Egr-2 HOXA5 aMEF-2 Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for KPNA6
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KPNA6 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p35.1 Ensembl cytogenetic band: 1p35.1 HGNC cytogenetic band: 1p35.1KPNA6 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P032573: view genomic region
(about GC identifiers)
Start:
|
32,573,639 bp from pter |
End:
|
32,642,169 bp from pter |
Size:
|
68,531 bases |
Orientation:
|
plus strand |
|
Proteins
for KPNA6 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: IMA7_HUMAN, O60684 (See
protein sequence)Recommended Name: Importin subunit alpha-7 Size: 536 amino acids; 60030 Da
Subunit: Interacts with ZIC3 (By similarity). Forms a complex with importin subunit beta-1
Secondary accessions: B2RDC7 D3DPP5 Q5VVU3Explore the universe of human proteins at neXtProt for KPNA6: NX_O60684
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O60684
KPNA6 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_036448.1
ENSEMBL proteins: ENSP00000362728 ENSP00000415677 ENSP00000440609 ENSP00000444930
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
KPNA6 for ontologies About GeneDecksing
KPNA6 Antibody Products:
Assay Products for KPNA6: |
Protein
Domains /
Families
for KPNA6 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KPNA6 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O60684ProtoNet protein and cluster: O60684 2 Blocks protein families: IPB000225 Armadillo repeat IPB002652 Importin alpha-like protein
UniProtKB/Swiss-Prot: IMA7_HUMAN, O60684Similarity: Belongs to the importin alpha familySimilarity: Contains 10 ARM repeatsSimilarity: Contains 1 IBB domain |
Function
for KPNA6 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: IMA7_HUMAN, O60684Function: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically anddirectly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex tothe nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex issubsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic sideof the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exportedfrom the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclearimport is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between thecytoplasm and nucleus
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KPNA6 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KPNA6 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: KPNA6 (NM_012316) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KPNA6 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KPNA6 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KPNA6 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
-- | -- | | GO:0008565 | protein transporter activity |
IEA | -- |
KPNA6 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Kpna6tm1Bdr for KPNA6
2 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Kpna6):
KPNA6 for phenotypes About GeneDecksing
|
Pathways & Interactions
for KPNA6 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell cycle_Spindle assembly and chromosome separation | | | 2 | TNF-alpha/NF-kB Signaling Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for KPNA6
1  GeneGo (Thomson Reuters) Pathway for KPNA6
1  BioSystems Pathway for KPNA6
KPNA6 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KPNA6
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
5/223 Interacting proteins for KPNA6 (O606842, 3 ENSP000003627284) via UniProtKB, MINT, STRING, and/or I2D (see all 223)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006606 | protein import into nucleus |
-- | -- | | GO:0006607 | NLS-bearing substrate import into nucleus |
TAS | 9395085 |
KPNA6 for ontologies About GeneDecksing
|
Drugs & Compounds
for KPNA6 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KPNA6
1 HMDB Compound for KPNA6 About this table
Search CenterWatch for drugs/clinical trials and news about KPNA6 / IMA7
|
Transcripts
for KPNA6 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KPNA6 gene: NM_012316.4 Unigene Clusters for KPNA6: Karyopherin alpha 6 (importin alpha 7) Hs.470588 [show with all ESTs], Hs.711019 Unigene Representative Sequences: NM_012316, AK0007246 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000373625(uc001bug.3 uc001buh.3 uc010ogx.2 uc010ogy.2)
ENST00000471599 ENST00000469790 ENST00000446515 ENST00000545542 ENST00000537234
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KPNA6 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KPNA6 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KPNA6 (NM_012316) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KPNA6 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KPNA6 |
Additional cDNA sequence: AK000724.1 21 DOTS entries: DT.95265986 DT.413991 DT.100812266 DT.101960555 DT.100777992 DT.95363854 DT.95124203 DT.97846825 DT.100686859 DT.100805004 DT.121341539 DT.121341548 DT.121341609 DT.91755387 DT.95190126 DT.121341583 DT.40106976 DT.86852720 DT.91755385 DT.95168647 DT.95168649 24/333 AceView cDNA sequences (see all 333): AI264187 CA394520 AA488342 CB529320 AJ573118 BU618021 AU129978 CB158122 BF593118 BF589066 AW006715 CN481317 AI623423 BU739026 BP345086 BM996784 AA777971 AI381012 AA374984 AI362856 AA993106 BE785517 BG106162 AI273196
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for KPNA6 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for KPNA6
|
Expression
for KPNA6 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KPNA6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCATTGAGTG
About this image
See KPNA6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KPNA6
SOURCE GeneReport for Unigene clusters: Hs.470588 Hs.711019
UniProtKB/Swiss-Prot: IMA7_HUMAN, O60684Tissue specificity: Widely expressed
SABiosciences Custom PCR Arrays for KPNA6
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KPNA6
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KPNA6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KPNA6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KPNA6 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KPNA6 |
Orthologs
for KPNA6 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for KPNA6 gene from 8/34 species (see all 34) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
KPNA61 |
karyopherin alpha 6 (importin alpha 7) |
80.62(n)
94.58(a) |
|
419656 NM_001012841.2 NP_001012859.2 |
lizard
(Anolis carolinensis) |
Reptilia |
KPNA66 |
-- |
91(a) |
1 ↔ 1 |
GL343706.1(179343-187905) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BJ618206.12 |
-- |
76.8(n) |
|
BJ618206.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC1001498521 |
importin subunit alpha-7-like |
75.87(n)
88.81(a) |
|
100149852 XM_001923886.2 XP_001923921.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Kap-alpha11 , 3 |
protein-nucleus import protein carrier3
karyopherin alpha11 |
62(a)
(best of 2)3
60.8(n)1
65.75(a)1 |
|
76C63
401601 NM_079443.11 NP_524167.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
SRP1(YNL189W)4
SRP11 |
Karyopherin alpha homolog, forms a dimer with karyopherin more4
Srp1p1 |
54.27(n)1
54.8(a)1 |
|
14(284260-285888)4
8555321, 4 NP_014210.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
IMPA-21 |
importin alpha isoform 2 |
57.28(n)
56.89(a) |
|
827302 NM_001160767.1 NP_001154239.1 |
rice
(Oryza sativa) |
Liliopsida |
AB024311.12 |
-- |
77.02(n) |
|
AB024311.1 |
ENSEMBL Gene Tree for KPNA6 (if available)
TreeFam Gene Tree for KPNA6 (if available) |
Paralogs
for KPNA6 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KPNA6 gene
- KPNA32 KPNA72 SPAG62 KPNA52 KPNA22 KPNA42 KPNA12
6 SIMAP similar genes for KPNA6 using alignment to 6 protein entries: IMA7_HUMAN (see all proteins):KPNA5 KPNA1 KPNA3 KPNA4 KPNA2 KPNA7
KPNA6 for paralogs About GeneDecksing
|
Genomic Variants
for KPNA6 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KPNA6 (32573639 - 32642169 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for KPNA6: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KPNA6 |
|
Disorders
/ Diseases
for KPNA6 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KPNA6 for disorders About GeneDecksing
OMIM gene information: 610563
OMIM disorders: --
3  diseases for KPNA6: About MalaCardsataxia immunodeficiency malaria
Export disorders for KPNA6 gene to outside databases
|
Publications
for KPNA6 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KPNA6 gene, integrated from 9 sources (see all 78):
(articles sorted by number of sources associating them with KPNA6) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Evidence for distinct substrate specificities of importin alpha family members in nuclear protein import. (PubMed id 10523667)1, 2, 3, 9 Koehler M.... Hartmann E. (1999)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Regulation of Stat3 nuclear import by importin alpha5 and importin alpha7 via two different functional sequence elements. (PubMed id 16298512)1, 9 Ma J. and Cao X. (2006)
- Acetylation of importin-alpha nuclear import factors by CBP/p300. (PubMed id 10801418)1, 9 Bannister A.J....Kouzarides T. (2000)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Cellular cofactors of lentiviral integrase: from targe t validation to drug discovery. (PubMed id 22928108)1 Taltynov O....Debyser Z. (2012)
- Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
|
External Searches for KPNA6 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KPNA6 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KPNA6 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KPNA6 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KPNA6 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for KPNA6 gene:
Search GeneIP for patents involving KPNA6
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KPNA6 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for KPNA6 | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KPNA6 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KPNA6 | | | OriGene Protein Over-expression Lysate for KPNA6 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KPNA6 | | OriGene 3'-UTR Clone for KPNA6 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KPNA6 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KPNA6 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for KPNA6 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KPNA6 | | OriGene Custom Protein Services for KPNA6 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KPNA6 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KPNA6 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KPNA6 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KPNA6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KPNA6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KPNA6 |
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| | | | Search Tocris compounds for KPNA6 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KPNA6 |
|  |  |  | | | | ThermoFisher Antibodies for KPNA6 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KPNA6 |
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