Aliases for KNTC1 Gene
External Ids for KNTC1 Gene
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. Experimental evidence indicated that the encoded protein functioned in a similar manner to that of the Drosophila rough deal protein. [provided by RefSeq, Jul 2008]
GeneCards Summary for KNTC1 Gene
KNTC1 (Kinetochore Associated 1) is a Protein Coding gene. Diseases associated with KNTC1 include histrionic personality disorder and dependent personality disorder. Among its related pathways are Cell Cycle, Mitotic and Cell Cycle, Mitotic.
UniProtKB/Swiss-Prot for KNTC1 Gene
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores.