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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KNTC1 Gene

protein-coding   GIFtS: 56
GCID: GC12P123011

Kinetochore Associated 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Kinetochore Associated 11 2     Rough Deal Homolog, Centromere/Kinetochore Protein2
ROD2 5     HsROD3
KIAA01663 5     Rod3
Rough Deal Homolog (Drosophila)1     hRod3
Kinetochore-Associated Protein 12     Rough Deal Homolog3

External Ids:    HGNC: 172551   Entrez Gene: 97352   Ensembl: ENSG000001844457   OMIM: 6073635   UniProtKB: P507483   

Export aliases for KNTC1 gene to outside databases

Previous GC identifers: GC12M121730 GC12U900005 GC12P122820 GC12P121450 GC12P121451 GC12P121536 GC12P121577 GC12P119972


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for KNTC1 Gene:
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation
during cell division. Experimental evidence indicated that the encoded protein functioned in a similar manner to
that of the Drosophila rough deal protein. (provided by RefSeq, Jul 2008)

GeneCards Summary for KNTC1 Gene: 
KNTC1 (kinetochore associated 1) is a protein-coding gene. Diseases associated with KNTC1 include orbital plasma cell granuloma, and histrionic personality disorder, and among its related super-pathways are Mitotic Anaphase and Mitotic Prometaphase. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: KNTC1_HUMAN, P50748
Function: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis.
Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_009755.19  NC_018923.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KNTC1 gene promoter:
         Max1   Elk-1   Lmo2   E4BP4   HEN1   PPAR-gamma2   Pax-4a   NF-kappaB1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKNTC1 promoter sequence
   Search SABiosciences Chromatin IP Primers for KNTC1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KNTC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.31   Ensembl cytogenetic band:  12q24.31   HGNC cytogenetic band: 12q24.31

KNTC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KNTC1 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P123011:  view genomic region     (about GC identifiers)

Start:
123,011,793 bp from pter      End:
123,110,947 bp from pter
Size:
99,155 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KNTC1_HUMAN, P50748 (See protein sequence)
Recommended Name: Kinetochore-associated protein 1  
Size: 2209 amino acids; 250749 Da
Subunit: Interacts with ZW10. This interaction is required for stable association with the kinetochore. Component
of the RZZ complex composed of KNTC1/ROD, ZW10 and ZWILCH
Subcellular location: Cytoplasm. Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle.
Note=Dynamic pattern of localization during the cell cycle. At interphase, uniformly distributed throughout the
cytoplasm and nucleus. By prophase and until late stages of prometaphase, a fraction of the total pool is
concentrated at kinetochores. By metaphase, detected at kinetochores, along spindle fibers and most prominently
at the poles. By late anaphase until the end of telophase, no longer detectable on kinetochores or along spindle
fibers, but still present at the spindle poles
Sequence caution: Sequence=BAA11483.2; Type=Erroneous initiation;
Secondary accessions: A7E2C4

Explore the universe of human proteins at neXtProt for KNTC1: NX_P50748

Explore proteomics data for KNTC1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P50748

  • KNTC1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KNTC1 Protein Expression
    REFSEQ proteins: NP_055523.1  
    ENSEMBL proteins: 
     ENSP00000397992   ENSP00000328236   ENSP00000397140   ENSP00000408760   ENSP00000439119  
     ENSP00000437344   ENSP00000443622  
    Reactome Protein details: P50748
    Human Recombinant Protein Products for KNTC1: 
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    Cloud-Clone Corp. Proteins for KNTC1 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000777condensed chromosome kinetochore IEA--
    GO:0000922spindle pole IDA11146660
    GO:0005634nucleus NAS11146660
    GO:0005828kinetochore microtubule IDA11146660
    GO:0005829cytosol TAS--

    KNTC1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR019527 RZZ-complex_KNTC1/ROD_C

    Graphical View of Domain Structure for InterPro Entry P50748

    ProtoNet protein and cluster: P50748


    KNTC1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KNTC1_HUMAN, P50748
    Function: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis.
    Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI11146660
         
    KNTC1 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for KNTC1:
     Decreased number of cells in m  Increased cell death in breast  Lamellipodia cells 

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for KNTC1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1M Phase
    Mitotic Anaphase0.94
    M Phase0.88
    Separation of Sister Chromatids0.94
    Mitotic M-M/G1 phases0.88
    Mitotic Metaphase and Anaphase0.94
    2Resolution of Sister Chromatid Cohesion
    Resolution of Sister Chromatid Cohesion0.93
    Mitotic Prometaphase0.93
    3Cell Cycle
    Cell Cycle, Mitotic0.84
    Cell Cycle0.84

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/9        Reactome Pathways for KNTC1 (see all 9)
        Mitotic Metaphase and Anaphase
    Mitotic Prometaphase
    Resolution of Sister Chromatid Cohesion
    Mitotic Anaphase
    Cell Cycle



    KNTC1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for KNTC1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    4 Interacting proteins for KNTC1 (P507483 ENSP000003971404) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    VHLP403373I2D: score=2 
    ZW10O432643I2D: score=2 
    ZWILCHQ9H9003I2D: score=1 
    --ensp: ENSP000003282364STRING: ensp: ENSP00000328236
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0006461protein complex assembly NAS11146660
    GO:0007067mitosis IEA--
    GO:0007093mitotic cell cycle checkpoint IDA11146660

    KNTC1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KNTC1

    Search CenterWatch for drugs/clinical trials and news about KNTC1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KNTC1 gene: 
    NM_014708.4  

    Unigene Cluster for KNTC1:

    Kinetochore associated 1
    Hs.300559  [show with all ESTs]
    Unigene Representative Sequence: BC150278
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000535410 ENST00000450485 ENST00000333479(uc001ucv.3 uc010taf.2)
    ENST00000535186 ENST00000423927 ENST00000545065 ENST00000377192 ENST00000436959
    ENST00000541466 ENST00000546125 ENST00000536625 ENST00000542727 ENST00000539013
    ENST00000541427 ENST00000534995 ENST00000537348
    miRNA
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    Inhib. RNA
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    Additional mRNA sequence: 

    AK093470.1 AK293403.1 AK303337.1 BC150278.1 D79988.1 

    15 DOTS entries:

    DT.114572  DT.100783292  DT.114574  DT.92426914  DT.91754770  DT.95289644  DT.100716343  DT.102826270 
    DT.86848374  DT.91648596  DT.92426907  DT.92426909  DT.92426911  DT.86851106  DT.97804374 

    24/131 AceView cDNA sequences (see all 131):

    D79988 AA563881 AA157787 BF513370 BQ267926 AU142399 AI380277 BM794708 
    AK093470 AA417766 AV686551 AW235746 BM772271 AA282078 AW450633 BQ366585 
    AA582454 NM_014708 AW629521 BX364485 AU131338 BC055410 BM697763 BQ946378 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for KNTC1 (see all 8)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19a · 19b · 19c ^ 20 ^
    SP1:                                                                                                                          -           -                     
    SP2:                                                              -                                                                                             
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                              -                                                                                             

    ExUns: 21 ^ 22 ^ 23 ^ 24 ^ 25a · 25b ^ 26 ^ 27 ^ 28 ^ 29
    SP1:                                                            
    SP2:                                                            
    SP3:                                                            
    SP4:        -                                                   
    SP5:                                                            


    ECgene alternative splicing isoforms for KNTC1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KNTC1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAATAAATAA
    KNTC1 Expression
    About this image


    See KNTC1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KNTC1

    SOURCE GeneReport for Unigene cluster: Hs.300559

    UniProtKB/Swiss-Prot: KNTC1_HUMAN, P50748
    Tissue specificity: High expression in testis

        SABiosciences Expression via Pathway-Focused PCR Array including KNTC1: 
              Cell Cycle in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KNTC1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for KNTC1 gene from 7/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kntc11 , 5 kinetochore associated 11, 5 81.36(n)1
    81.21(a)1
      5 (63.17 cM)5
    2086281  NM_001042421.11  NP_001035886.11 
     1237497265 
    chicken
    (Gallus gallus)
    Aves KNTC11 kinetochore associated 1 67.45(n)
    61.35(a)
      416865  XM_415157.3  XP_415157.3 
    lizard
    (Anolis carolinensis)
    Reptilia KNTC16
    kinetochore associated 1
    51(a)
    1 ↔ 1
    GL343423.1(226934-306190)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.96222 Xenopus laevis transcribed sequence with weak similarity more 74.38(n)    BX845940.1 
    zebrafish
    (Danio rerio)
    Actinopterygii kntc11 kinetochore associated 1 53.88(n)
    46.91(a)
      497376  XM_681266.5  XP_686358.5 
    fruit fly
    (Drosophila melanogaster)
    Insecta rod6
    rough deal
    18(a)
    1 ↔ 1
    3R(27406394-27413861)
    worm
    (Caenorhabditis elegans)
    Secernentea rod-16
    Protein ROD-1
    16(a)
    1 ↔ 1
    IV(7478452-7485519)


    ENSEMBL Gene Tree for KNTC1 (if available)
    TreeFam Gene Tree for KNTC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KNTC1 gene

    KNTC1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for KNTC1
    PGOHUM00000239596


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2108 SNPs in KNTC1 are shown (see all 2108)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs128163961,2
    C,F--122825103(+) TCGAAA/TCATAG 1 -- us2k16Minor allele frequency- T:0.17NA CSA WA EA 363
    rs1872928611,2
    --122825171(+) TCTAGA/GGGACT 1 -- us2k10--------
    rs1932010951,2
    --122825177(+) GGACTA/GTCTTT 1 -- us2k10--------
    rs1129519501,2
    C,F--122825317(+) GGTCAG/AGAGTT 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs749769001,2
    C,F--123013673(+) GGTGTG/TAGCCA 1 -- int12Minor allele frequency- T:0.06NA 124
    rs354165561,2
    C,F--123013680(+) GCCACC/TGCGCC 1 -- int12Minor allele frequency- T:0.06NA 124
    rs1840103321,2
    --123013682(+) CACCGC/TGCCGG 1 -- int10--------
    rs1509997241,2
    --123013751(+) GATCAC/TCCAAG 1 -- int10--------
    rs1882840961,2
    --123013765(+) AGCTGC/TCTAGT 1 -- int10--------
    rs751525641,2
    F--123013859(+) CTTATG/AAAACC 1 -- int11Minor allele frequency- A:0.02WA 118

    HapMap Linkage Disequilibrium report for KNTC1 (123011793 - 123110947 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for KNTC1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2658251CNV Deletion23128226
    esv2661880CNV Deletion23128226
    nsv826530CNV Loss20364138
    nsv826529CNV Gain20364138
    nsv899570CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607363    OMIM disorders: --

    10 diseases for KNTC1:    About MalaCards
    orbital plasma cell granuloma    histrionic personality disorder    dependent personality disorder    osteitis fibrosa
    personality disorder    hyperphosphatemia    renal osteodystrophy    osteomalacia
    hyperparathyroidism    narcolepsy

    7 diseases from the University of Copenhagen DISEASES database for KNTC1:
    Renal osteodystrophy     Osteomalacia     Hyperparathyroidism     Osteitis fibrosa
    Kidney failure     Histrionic personality disorder     Dependent personality disorder

    KNTC1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): KNTC1
    Human Genome Epidemiology (HuGE) Navigator: KNTC1 (3 documents)

    Export disorders for KNTC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KNTC1 gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with KNTC1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The ZW10 and Rough Deal checkpoint proteins function together in a large, evolutionarily conserved complex targeted to the kinetochore. (PubMed id 11590237)1, 2, 3 Scaeerou F....Goldberg M.L. (2001)
    2. Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores. (PubMed id 11146660)1, 2, 3 Chan G.K.T.... Yen T.J. (2000)
    3. Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions. (PubMed id 12686595)1, 2, 9 Williams B.C....Goldberg M.L. (2003)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    5. An approach based on a genome-wide association study reveals candidate loci for narcolepsy. (PubMed id 20677014)1, 4 Shimada M....Tokunaga K. (2010)
    6. ZW10 links mitotic checkpoint signaling to the structural kinetochore. (PubMed id 15824131)1, 2 Kops G.J.P.L.... Cleveland D.W. (2005)
    7. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8724849)1, 2 Nagase T.... Nomura N. (1996)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. (PubMed id 22479202)4 Dastani Z....Kathiresan S. (2012)
    10. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9735 HGNC: 17255 AceView: KNTC1 Ensembl:ENSG00000184445 euGenes: HUgn9735
    ECgene: KNTC1 H-InvDB: KNTC1

    (According to HUGE)
    About This Section
    HUGE: KIAA0166

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KNTC1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KNTC1 gene:
    Search GeneIP for patents involving KNTC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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