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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KNSTRN Gene

protein-coding   GIFtS: 41
GCID: GC15P040675

Kinetochore-Localized Astrin/SPAG5 Binding Protein

(Previous name: chromosome 15 open reading frame 23)
(Previous symbol: C15orf23)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Kinetochore-Localized Astrin/SPAG5 Binding Protein1 2     TRAF4-Associated Factor 12 3
C15orf231 2 3     Chromosome 15 Open Reading Frame 231
Kinetochore-Localized Astrin-Binding Protein1 2 3     kinastrin2
Small Kinetochore-Associated Protein1 2     Putative TRAF4-Associated Factor 12
TRAF4 Associated Factor 11 2     Small Kinetochore Associated Protein2
Kinetochore-Localized Astrin/SPAG5-Binding Protein2 3     Small Kinetochore-Associated Protein, Kinetochore-Localized Astrin-Binding
Protein, TRAF4 Associated Factor 12
SKAP2 3     Kinastrin3
TRAF4AF12 3     

External Ids:    HGNC: 307671   Entrez Gene: 904172   Ensembl: ENSG000001289447   OMIM: 6147185   UniProtKB: Q9Y4483   

Export aliases for KNSTRN gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for KNSTRN Gene: 
KNSTRN (kinetochore-localized astrin/SPAG5 binding protein) is a protein-coding gene. Diseases associated with KNSTRN include prostatitis. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: SKAP_HUMAN, Q9Y448
Function: Essential component of the mitotic spindle required for faithful chromosome segregation and progression
into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal
timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin
(SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NT_010194.17  NC_018926.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for KNSTRN
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKNSTRN promoter sequence
   Search SABiosciences Chromatin IP Primers for KNSTRN

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KNSTRN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q15.1   Ensembl cytogenetic band:  15q15.1   HGNC cytogenetic band: 15q15.1

KNSTRN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KNSTRN gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P040675:  view genomic region     (about GC identifiers)

Start:
40,674,922 bp from pter      End:
40,686,489 bp from pter
Size:
11,568 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SKAP_HUMAN, Q9Y448 (See protein sequence)
Recommended Name: Small kinetochore-associated protein  
Size: 316 amino acids; 35438 Da
Subunit: Part of an astrin (SPAG5)-kinastrin (SKAP) complex containing KNSTRN, SPAG5, PLK1, DYNLL1 and SGOL2.
Interacts with SPAG5. Directly binds to microtubules, although at relatively low affinity. Interacts with CENPE;
this interaction greatly favors microtubule-binding
Subcellular location: Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.
Note=Colocalizes with microtubules around centrosomes in prophase and with the mitotic spindle at prometaphase
and metaphase. From late prometaphase to anaphase, is highly concentrated on kinetochores. Located at the
kinetochore-microtubule interface. The astrin (SPAG5)-kinastrin (SKAP) complex localizes to the microtubule plus
ends
Sequence caution: Sequence=AAH04543.1; Type=Erroneous termination; Positions=174; Note=Translated as Glu;
Sequence=AAH14060.1; Type=Erroneous termination; Positions=174; Note=Translated as Glu; Sequence=AAI07803.1;
Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: B4DXA7 Q147U5 Q32Q57 Q5ISJ0 Q6P2S5 Q6PJM0 Q86XB4
Alternative splicing: 3 isoforms:  Q9Y448-1   Q9Y448-2   Q9Y448-3   

Explore the universe of human proteins at neXtProt for KNSTRN: NX_Q9Y448

Explore proteomics data for KNSTRN at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y448

  • KNSTRN Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KNSTRN Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001136233.1  NP_001136234.1  NP_150628.3  

    ENSEMBL proteins: 
     ENSP00000391233   ENSP00000453213   ENSP00000249776   ENSP00000393001   ENSP00000453126  
     ENSP00000454086   ENSP00000452788   ENSP00000452758   ENSP00000453421   ENSP00000453867  

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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000776kinetochore IDA--
    GO:0000777condensed chromosome kinetochore IEA--
    GO:0000922spindle pole IEA--
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--

    KNSTRN for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q9Y448


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SKAP_HUMAN, Q9Y448
    Function: Essential component of the mitotic spindle required for faithful chromosome segregation and progression
    into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal
    timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin
    (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments
    Induction: Degraded at the end of mitosis. Down-regulated upon exposure to nitric oxide

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    KNSTRN for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for KNSTRN:
     Decreased TP53 protein express 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for KNSTRN 
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KNSTRN

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/8 Interacting proteins for KNSTRN (Q9Y4482, 3 ENSP000002497764) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAPK6Q166592, 3MINT-8260790 I2D: score=2 
    MPP6Q9NZW53, ENSP000002226444I2D: score=2 STRING: ENSP00000222644
    MPHOSPH6Q995473, ENSP000002581694I2D: score=2 STRING: ENSP00000258169
    C17orf59Q96GS43I2D: score=3 
    CHMP1BQ7LBR13I2D: score=1 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000070mitotic sister chromatid segregation IMP--
    GO:0000090mitotic anaphase ----
    GO:0007051spindle organization IMP--
    GO:0007059chromosome segregation IMP--
    GO:0051301cell division IEA--

    KNSTRN for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KNSTRN (SKAP)

    Search CenterWatch for drugs/clinical trials and news about KNSTRN / SKAP

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KNSTRN gene (3 alternative transcripts): 
    NM_001142761.1  NM_001142762.1  NM_033286.3  

    Unigene Cluster for KNSTRN:

    Kinetochore-localized astrin/SPAG5 binding protein
    Hs.525796  [show with all ESTs]
    Unigene Representative Sequence: NM_001142761
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000559604 ENST00000416151(uc010ucp.2) ENST00000560981 ENST00000249776(uc001zll.3 uc001zlo.3 uc001zlm.3 uc001zln.3)
    ENST00000448395 ENST00000560321 ENST00000559591 ENST00000561196 ENST00000560220
    ENST00000561169 ENST00000559304 ENST00000557920 ENST00000560673 ENST00000559083
    ENST00000561367
    miRNA
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    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate KNSTRN
    SwitchGear 3'UTR luciferase reporter plasmidKNSTRN 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KNSTRN
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    Additional mRNA sequence: 

    AK027408.1 AK125765.1 AK298156.1 AK301887.1 AY652615.1 BC021124.1 BC045739.1 BC064344.1 
    BC107802.1 BC118559.1 BC118639.1 U81002.1 

    13 DOTS entries:

    DT.453882  DT.101984431  DT.100797920  DT.100797925  DT.121048253  DT.95304848  DT.100797919  DT.95304849 
    DT.87046763  DT.91970081  DT.92430055  DT.97800782  DT.97833412 

    24/210 AceView cDNA sequences (see all 210):

    AW161437 AA806901 BC021124 BU542865 AA748608 AI204008 BQ014579 BM460056 
    BG575314 BC004543 AA316232 BM747557 AI907498 BU857707 BQ010737 BU170928 
    AI754865 BE886561 CA419744 AA953422 BM904933 CR621728 BM457240 AI805936 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for KNSTRN (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b · 12c ·
    SP1:                                            -     -     -     -     -           -           -           -                             -                     
    SP2:                                            -     -     -     -                 -           -           -                             -                     
    SP3:                                            -     -     -     -                 -                       -                             -                     
    SP4:                                            -     -     -     -                 -           -           -                                                   
    SP5:                                            -     -     -     -                 -           -           -           -                 -                     

    ExUns: 12d
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for KNSTRN

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section
    See probesets specificity/sensitivity at GeneAnnot
    CGAP TAG: --


    KNSTRN expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Blood (Hematopoietic System)
             Proerythroblasts Hematopoietic Bone Marrow

    See KNSTRN Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KNSTRN

    SOURCE GeneReport for Unigene cluster: Hs.525796
        SABiosciences Custom PCR Arrays for KNSTRN
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KNSTRN

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for KNSTRN gene from 4/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Knstrn5
    D2Ertd750e1
    DNA segment, Chr 2, ERATO Doi 750, expressed1, 5 76.96(n)1
    69.13(a)1
      2 (59.46 cM)5
    519441  NM_026412.31  NP_080688.21 
     1188140035 
    chicken
    (Gallus gallus)
    Aves C5H15orf236
    putative TRAF4-associated factor 1
    31(a)
    1 ↔ 1
    5(792319-797351)
    lizard
    (Anolis carolinensis)
    Reptilia C15ORF236
    Uncharacterized protein
    27(a)
    1 ↔ 1
    GL343264.1(1087731-1098688)
    zebrafish
    (Danio rerio)
    Actinopterygii knstrn6
    kinetochore-localized astrin/SPAG5 binding protein...
    20(a)
    1 ↔ 1
    1(10291239-10301481)


    ENSEMBL Gene Tree for KNSTRN (if available)
    TreeFam Gene Tree for KNSTRN (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KNSTRN gene
    6 SIMAP similar genes for KNSTRN using alignment to 8 protein entries:     SKAP_HUMAN (see all proteins):
    EIF3L    AURA2    NF2    LINC00596    FAM175A    GLT8D2

    KNSTRN for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/332 SNPs in KNSTRN are shown (see all 332)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs733993171,2
    C,F--40672952(+) CAACAG/ACTCCC 3 -- us2k11Minor allele frequency- A:0.50WA 2
    rs1868326821,2
    --40672978(+) ATCCAA/GGCTCT 3 -- us2k10--------
    rs1114641291,2
    C,F--40673114(+) ACTCTA/GTCCAC 3 -- us2k13Minor allele frequency- G:0.06WA CSA 122
    rs176712501,2
    C,F,H--40673124(+) CACAAT/CTATTC 3 -- us2k126Minor allele frequency- C:0.07NA NS EA WA CSA 2896
    rs1920298161,2
    --40673175(+) GCTCAC/TGCCTG 3 -- us2k10--------
    rs1120396321,2
    C--40673437(+) TCTCC-/AAAAAA 3 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs781536291,2
    C,F--40673465(+) ATATAT/CATATA 3 -- us2k13Minor allele frequency- C:0.06WA NA EA 358
    rs775311641,2
    C,F--40673466(+) TATATA/GTATAA 3 -- us2k12Minor allele frequency- G:0.09WA NA 238
    rs1833292621,2
    --40673524(+) AACACC/TTTGGG 3 -- us2k10--------
    rs1493389341,2
    --40673569(+) TTTAAC/GACCAG 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for KNSTRN (40674922 - 40686489 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for KNSTRN: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing KNSTRN
    DNA2.0 Custom Variant and Variant Library Synthesis for KNSTRN

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614718    OMIM disorders: --

    2 diseases for KNSTRN:    About MalaCards
    prostatitis    


    KNSTRN for disorders           About GeneDecksing


    Export disorders for KNSTRN gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KNSTRN gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with KNSTRN)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. CENP-E kinesin interacts with SKAP protein to orchestr ate accurate chromosome segregation in mitosis. (PubMed id 22110139)1, 2 Huang Y....Yao X. (2012)
    2. SKAP associates with kinetochores and promotes the me taphase-to-anaphase transition. (PubMed id 19667759)1, 2 Fang L....Fang G. (2009)
    3. Analysis of differentially expressed genes in nitric oxide-exposed human monocytic cells. (PubMed id 15855057)1, 2 Turpaev K.... Drapier J.-C. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    7. Mitotic regulator SKAP forms a link between kinetochor e core complex KMN and dynamic spindle microtubules. (PubMed id 23035123)1 Wang X....Yao X. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 90417 HGNC: 30767 AceView: C15orf23 Ensembl:ENSG00000128944 euGenes: HUgn90417
    ECgene: KNSTRN H-InvDB: KNSTRN

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KNSTRN Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KNSTRN gene:
    Search GeneIP for patents involving KNSTRN

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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