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Aliases for KNOP1 Gene

Aliases for KNOP1 Gene

  • Lysine-Rich Nucleolar Protein 1 2 3
  • Testis-Specific Gene 118 Protein 3 4
  • C16orf88 3 4
  • FAM191A 3 4
  • TSG118 3 4
  • Family With Sequence Similarity 191, Member A 3
  • Family With Sequence Similarity 191 2
  • Chromosome 16 Open Reading Frame 88 2
  • Testis-Specific Gene 118 2
  • Protein C16orf88 3
  • Protein FAM191A 4
  • Member A 2
  • 101F10.1 3

External Ids for KNOP1 Gene

Previous Symbols for KNOP1 Gene

  • C16orf88

Summaries for KNOP1 Gene

GeneCards Summary for KNOP1 Gene

KNOP1 (Lysine-Rich Nucleolar Protein 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KNOP1 Gene

Genomics for KNOP1 Gene

Genomic Location for KNOP1 Gene

Start:
19,701,934 bp from pter
End:
19,718,353 bp from pter
Size:
16,420 bases
Orientation:
Minus strand

Genomic View for KNOP1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KNOP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KNOP1 Gene

No data available for Regulatory Elements for KNOP1 Gene

Proteins for KNOP1 Gene

  • Protein details for KNOP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q1ED39-KNOP1_HUMAN
    Recommended name:
    Lysine-rich nucleolar protein 1
    Protein Accession:
    Q1ED39
    Secondary Accessions:
    • O43328
    • Q5FWF3

    Protein attributes for KNOP1 Gene

    Size:
    458 amino acids
    Molecular mass:
    51589 Da
    Quaternary structure:
    • Interacts with ZNF106.
    SequenceCaution:
    • Sequence=AAC05805.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH89430.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};

neXtProt entry for KNOP1 Gene

Proteomics data for KNOP1 Gene at MOPED

Post-translational modifications for KNOP1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KNOP1 Gene

No data available for DME Specific Peptides for KNOP1 Gene

Domains for KNOP1 Gene

Protein Domains for KNOP1 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with KNOP1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for KNOP1 Gene

Function for KNOP1 Gene

Gene Ontology (GO) - Molecular Function for KNOP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with KNOP1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for KNOP1 Gene

Localization for KNOP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for KNOP1 Gene

Nucleus, nucleolus.

Gene Ontology (GO) - Cellular Components for KNOP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with KNOP1: view

Pathways for KNOP1 Gene

SuperPathways for KNOP1 Gene

No Data Available

Interacting Proteins for KNOP1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000219837%0d%0a9606.ENSP00000405965%0d%0a9606.ENSP00000376076%0d%0a
Selected Interacting proteins: ENSP00000219837 for KNOP1 Gene via STRING

Gene Ontology (GO) - Biological Process for KNOP1 Gene

None

No data available for Pathways by source for KNOP1 Gene

Transcripts for KNOP1 Gene

Unigene Clusters for KNOP1 Gene

Lysine-rich nucleolar protein 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KNOP1 Gene

No ASD Table

Relevant External Links for KNOP1 Gene

GeneLoc Exon Structure for
KNOP1
ECgene alternative splicing isoforms for
KNOP1

Expression for KNOP1 Gene

mRNA expression in normal human tissues for KNOP1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for KNOP1 Gene

SOURCE GeneReport for Unigene cluster for KNOP1 Gene Hs.585209

genes like me logo Genes that share expressions with KNOP1: view

Orthologs for KNOP1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KNOP1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C16H16orf88 36
  • 95.61 (n)
  • 93.64 (a)
KNOP1 37
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia KNOP1 36
  • 80.61 (n)
  • 74.72 (a)
KNOP1 37
  • 75 (a)
OneToOne
dog
(Canis familiaris)
Mammalia KNOP1 36
  • 81.37 (n)
  • 75.83 (a)
KNOP1 37
  • 75 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2310008H09Rik 16
Knop1 36
  • 72.8 (n)
  • 65.02 (a)
Knop1 37
  • 55 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KNOP1 37
  • 39 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC680982 36
  • 66.99 (n)
  • 53.96 (a)
chicken
(Gallus gallus)
Aves KNOP1 37
  • 47 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KNOP1 37
  • 46 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii knop1 37
  • 25 (a)
OneToOne
Species with no ortholog for KNOP1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KNOP1 Gene

ENSEMBL:
Gene Tree for KNOP1 (if available)
TreeFam:
Gene Tree for KNOP1 (if available)

Paralogs for KNOP1 Gene

genes like me logo Genes that share paralogs with KNOP1: view

No data available for Paralogs for KNOP1 Gene

Variants for KNOP1 Gene

Sequence variations from dbSNP and Humsavar for KNOP1 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs720173 -- 19,710,484(-) TCTGC(A/G)AGGAG intron-variant
rs720174 -- 19,710,433(-) CATGA(A/G)GAGTG intron-variant
rs720175 -- 19,710,409(-) AAGTA(C/T)GTCCA intron-variant
rs720176 -- 19,710,193(-) GCCAG(C/T)GGTGG intron-variant
rs1016971 -- 19,707,403(-) acaac(A/T)gtgtt intron-variant

Relevant External Links for KNOP1 Gene

HapMap Linkage Disequilibrium report
KNOP1

No data available for Structural Variations from Database of Genomic Variants (DGV) for KNOP1 Gene

Disorders for KNOP1 Gene

No disorders were found for KNOP1 Gene.

No data available for UniProtKB/Swiss-Prot for KNOP1 Gene

Publications for KNOP1 Gene

  1. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PMID: 10493829) Loftus B.J. … Adams M.D. (Genomics 1999) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. System-wide changes to SUMO modifications in response to heat shock. (PMID: 19471022) Golebiowski F. … Hay R.T. (Sci Signal 2009) 3
  4. Comparative proteomic analysis identifies a role for SUMO in protein quality control. (PMID: 21693764) Tatham M.H. … Hay R.T. (Sci Signal 2011) 3
  5. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3

Products for KNOP1 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate KNOP1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for KNOP1
    • Block miRNA regulation of KNOP1 using miScript Target Protectors

    Sources for KNOP1 Gene

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