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KNDC1 Gene

protein-coding   GIFtS: 51
GCID: GC10P134974

Kinase Non-Catalytic C-Lobe Domain (KIND) Containing 1

(Previous names: RasGEF domain family, member 2)
(Previous symbols: RASGEF2, C10orf23)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Kinase Non-Catalytic C-Lobe Domain (KIND) Containing 11 2     Ras-GEF Domain-Containing Family Member 22 3
C10orf231 2 3     KIND Domain-Containing Protein 12 3
RASGEF21 2 3     bB439H18.32
RasGEF Domain Family, Member 21 2     Protein Very KIND2
Cerebral Protein 92 3     KIAA17683
Kinase Non-Catalytic C-Lobe Domain-Containing Protein 12 3     VKIND3

External Ids:    HGNC: 293741   Entrez Gene: 854422   Ensembl: ENSG000001717987   UniProtKB: Q76NI13   

Export aliases for KNDC1 gene to outside databases

Previous GC identifers: GC10P134448 GC10P134862 GC10P128521


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for KNDC1 Gene:
KNDC1 (kinase non-catalytic C-lobe domain (KIND) containing 1) is a protein-coding gene. Diseases associated with KNDC1 include cerebritis, and alzheimer's disease. GO annotations related to this gene include protein serine/threonine kinase activity and Ras guanyl-nucleotide exchange factor activity.

UniProtKB/Swiss-Prot: VKIND_HUMAN, Q76NI1
Function: Probable guanine nucleotide exchange factor (GEF)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000010.11  NC_018921.2  NT_030059.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the KNDC1 gene promoter:
         E2F-5   Elk-1   HOXA3   Sp1   Ik-3   Roaz   C/EBPalpha   CREB   deltaCREB   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKNDC1 promoter sequence
   Search Chromatin IP Primers for KNDC1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KNDC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q26.3   Ensembl cytogenetic band:  10q26.3   HGNC cytogenetic band: 10q26.3

KNDC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KNDC1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P134974:  view genomic region     (about GC identifiers)

Start:
134,973,951 bp from pter      End:
135,039,916 bp from pter
Size:
65,966 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: VKIND_HUMAN, Q76NI1 (See protein sequence)
Recommended Name: Protein very KIND  
Size: 1749 amino acids; 191397 Da
Sequence caution: Sequence=BAB21859.1; Type=Erroneous initiation; Sequence=CAI17339.1; Type=Erroneous gene model
prediction;
Secondary accessions: B0QZC5 Q5T233 Q6ZNH8 Q8TEE5 Q96LV7 Q9C095
Alternative splicing: 6 isoforms:  Q76NI1-1   Q76NI1-2   Q76NI1-3   Q76NI1-4   Q76NI1-5   Q76NI1-6   

Explore the universe of human proteins at neXtProt for KNDC1: NX_Q76NI1

Explore proteomics data for KNDC1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KNDC1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_689856.6  
    ENSEMBL proteins: 
     ENSP00000304437   ENSP00000357560   ENSP00000357561  

    KNDC1 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    5 InterPro protein domains:
     IPR011009 Kinase-like_dom
     IPR011019 KIND
     IPR023578 Ras_GEF_dom
     IPR000651 Ras-like_Gua-exchang_fac_N
     IPR001895 RasGRF_CDC25

    Graphical View of Domain Structure for InterPro Entry Q76NI1

    ProtoNet protein and cluster: Q76NI1

    1 Blocks protein domain: IPB001895 Guanine-nucleotide dissociation stimulator CDC25

    UniProtKB/Swiss-Prot: VKIND_HUMAN, Q76NI1
    Similarity: Contains 2 KIND domains
    Similarity: Contains 1 N-terminal Ras-GEF domain
    Similarity: Contains 1 Ras-GEF domain


    KNDC1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: VKIND_HUMAN, Q76NI1
    Function: Probable guanine nucleotide exchange factor (GEF)

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0005085guanyl-nucleotide exchange factor activity ----
    GO:0005088Ras guanyl-nucleotide exchange factor activity IEA--
    GO:0005515protein binding ----
         
    KNDC1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for KNDC1:
     Decreased Hepatitis C virus re 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Kndc1):
     normal 

    KNDC1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Kndc1tm1Mnkm for KNDC1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KNDC1
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    hsa-miR-186 hsa-miR-299-3p
    SwitchGear 3'UTR luciferase reporter plasmidKNDC1 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005622intracellular ----
    GO:0030425dendrite IEA--
    GO:0032045guanyl-nucleotide exchange factor complex IEA--
    GO:0043025neuronal cell body IEA--

    KNDC1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KNDC1
    Interactions:

        Search GeneGlobe Interaction Network for KNDC1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    Selected Interacting proteins for KNDC1 (Q76NI13 ENSP000003044374) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAP2P111373, ENSP000003535084I2D: score=1 STRING: ENSP00000353508
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    DGKIENSP000002884904STRING: ENSP00000288490
    PDE3BENSP000002820964STRING: ENSP00000282096
    RAP1AENSP000003487864STRING: ENSP00000348786
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001934positive regulation of protein phosphorylation IEA--
    GO:0007264small GTPase mediated signal transduction IEA--
    GO:0008150biological_process ND--
    GO:0021707cerebellar granule cell differentiation IEA--
    GO:0048814regulation of dendrite morphogenesis IEA--

    KNDC1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KNDC1 (VKIND)

    3 HMDB Compounds for KNDC1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine diphosphate5'-GDP (see all 10)146-91-8--
    Guanosine monophosphate5'-GMP (see all 14)85-32-5--
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for KNDC1 gene: 
    NM_152643.6  

    Unigene Cluster for KNDC1:

    Kinase non-catalytic C-lobe domain (KIND) containing 1
    Hs.530685  [show with all ESTs]
    Unigene Representative Sequence: NM_152643
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000304613(uc001llz.1) ENST00000478074 ENST00000485110 ENST00000530127
    ENST00000368571(uc001lma.1) ENST00000368572

    miRNA
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    2 qRT-PCR Assays for microRNAs that regulate KNDC1:
    hsa-miR-186 hsa-miR-299-3p
    SwitchGear 3'UTR luciferase reporter plasmidKNDC1 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: KNDC1 (NM_152643)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KNDC1
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KNDC1
      QuantiTect SYBR Green Assays in human, mouse, rat KNDC1
      QuantiFast Probe-based Assays in human, mouse, rat KNDC1

    Additional mRNA sequence: 

    AB000781.1 AB051555.1 AK057756.1 AK131205.1 AK294170.1 AL832201.1 BC047924.1 

    11 DOTS entries:

    DT.403522  DT.100008913  DT.40296298  DT.99972066  DT.91851090  DT.91972624  DT.92056182  DT.95242277 
    DT.121215069  DT.40237804  DT.91751688 

    Selected AceView cDNA sequences (see all 56):

    BX488662 BI824867 NM_152643 BU689478 AI217057 BM691964 AI963862 AB051555 
    NM_033404 BI489799 BF513407 CB156302 AK131205 BQ719533 BM547596 AK057756 
    AI692620 AW449871 AK090457 BQ188321 AA854407 AK074179 BX097618 AA723163 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for KNDC1 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a · 21b ^
    SP1:                                      -     -     -     -                 -                                                                             -   
    SP2:                                      -     -     -     -                 -                                                                             -   
    SP3:                                                                                                                                                            
    SP4:              -     -                 -     -                                                                                                               
    SP5:              -     -                 -                                                                                                                     

    ExUns: 22 ^ 23 ^ 24a · 24b ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34
    SP1:                                                                                    
    SP2:                                                                                    
    SP3:                                                                                    
    SP4:                                                                                    
    SP5:                                                                                    


    ECgene alternative splicing isoforms for KNDC1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KNDC1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTCCCTCCC
    KNDC1 Expression
    About this image

    KNDC1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KNDC1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.530685

    UniProtKB/Swiss-Prot: VKIND_HUMAN, Q76NI1
    Tissue specificity: Expressed specifically in the cerebral cortex

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KNDC1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for KNDC1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kndc11 , 5 kinase non-catalytic C-lobe domain (KIND) containing more1, 5 78.7(n)1
    78.54(a)1
      7 (84.89 cM)5
    764841  NM_177261.41  NP_796235.41 
     1398946965 
    chicken
    (Gallus gallus)
    Aves KNDC11 kinase non-catalytic C-lobe domain (KIND) containing more 58.39(n)
    57.95(a)
      423824  XM_421694.4  XP_421694.4 
    lizard
    (Anolis carolinensis)
    Reptilia KNDC16
    kinase non-catalytic C-lobe domain (KIND) containi...
    65(a)
    1 ↔ 1
    GL343262.1(208537-320934)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia kndc11 kinase non-catalytic C-lobe domain (KIND) containing more 60.6(n)
    58.23(a)
      100495169  XM_002937134.2  XP_002937180.2 
    zebrafish
    (Danio rerio)
    Actinopterygii KNDC1 (1 of 2)6
    KNDC1 (2 of 2)6
    kinase non-catalytic C-lobe domain (KIND) containi...
    kinase non-catalytic C-lobe domain (KIND) containi...
    43(a)
    32(a)
    many → 1
    many → 1
    Zv9_NA856(21016-41615) ENSDARG00000059910
    Zv9_NA97(20620-44236) ENSDARG00000090897


    ENSEMBL Gene Tree for KNDC1 (if available)
    TreeFam Gene Tree for KNDC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KNDC1 gene
    1 SIMAP similar gene for KNDC1 using alignment to 3 protein entries:     VKIND_HUMAN (see all proteins):
    FLJ00378

    KNDC1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for KNDC1
    PGOHUM00000245749


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KNDC1 (see all 2212)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1932464971,2
    --128519756(+) GGGCAA/GGGCCT 1 -- us2k10--------
    rs1114942281,2
    C,F--128519790(+) TCCTCG/ACTCCA 1 -- us2k11Minor allele frequency- A:0.00CSA 1
    rs44022061,2
    C,F,H--128519826(+) GCCTCC/TAGCAG 1 -- us2k115Minor allele frequency- T:0.36NS EA NA WA CSA 789
    rs40734821,2
    C--128519896(+) GAAGAA/GTTGGA 1 -- us2k10--------
    rs1866039841,2
    C--128519941(+) ACCACA/GGACCT 1 -- us2k10--------
    rs43267101,2
    C,F,A,H--128519958(+) GCAGCC/TGGGAA 1 -- us2k1 tfbs324Minor allele frequency- T:0.35NS EA WA NA CSA 2339
    rs40760431,2
    C,F,H--128520000(+) TCCTCG/AGGAGG 1 -- us2k19Minor allele frequency- A:0.14NS EA WA NA 632
    rs1915022031,2
    --128520019(+) CCAGCA/GCATGC 1 -- us2k10--------
    rs1480350651,2
    --128520055(+) GGCAGA/GAGGGC 1 -- us2k10--------
    rs44349171,2
    C,F,A,H--128520156(+) TGGGGC/AGATGA 1 -- us2k122Minor allele frequency- A:0.42NA NS EA WA CSA 2476

    HapMap Linkage Disequilibrium report for KNDC1 (134973951 - 135039916 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for KNDC1 (see all 50):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1106376CNV Deletion17803354
    esv1976405CNV Deletion18987734
    esv1549920CNV Deletion17803354
    esv2151232CNV Deletion18987734
    esv2743838CNV Deletion23290073
    esv2743835CNV Deletion23290073
    esv2583286CNV Deletion19546169
    esv2743837CNV Deletion23290073
    esv3360CNV Deletion18987735
    esv2657046CNV Deletion23128226

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    3 diseases for KNDC1:    
    About MalaCards
    cerebritis    alzheimer's disease    neuronitis


    KNDC1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): KNDC1
    Human Genome Epidemiology (HuGE) Navigator: KNDC1 (1 document)

    Export disorders for KNDC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

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    PubMed articles for KNDC1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with KNDC1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    3. Proteomic profiling of Myc-associated proteins. (PubMed id 21150319)1 Agrawal P....Sedivy J.M. (Cell Cycle 2010)
    4. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    5. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PubMed id 16751776)1 Girard A....Carmell M.A. (Nature 2006)
    6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)2 Deloukas P.... Rogers J. (Nature 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 85442 HGNC: 29374 AceView: KNDC1 Ensembl:ENSG00000171798 euGenes: HUgn85442
    ECgene: KNDC1 H-InvDB: KNDC1

    (According to HUGE)
    About This Section

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    HUGE: KIAA1768

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for KNDC1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for KNDC1 gene:
    Search GeneIP for patents involving KNDC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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