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Aliases for KNCN Gene

Aliases for KNCN Gene

  • Kinocilin 2 3
  • Kino 3
  • L5 3

External Ids for KNCN Gene

Previous GeneCards Identifiers for KNCN Gene

  • GC01M046783
  • GC01M047011
  • GC01M045127

Summaries for KNCN Gene

GeneCards Summary for KNCN Gene

KNCN (Kinocilin) is a Protein Coding gene.

UniProtKB/Swiss-Prot for KNCN Gene

  • May play a role in stabilizing dense microtubular networks or in vesicular trafficking.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KNCN Gene

Genomics for KNCN Gene

Regulatory Elements for KNCN Gene

Genomic Location for KNCN Gene

46,545,638 bp from pter
46,551,657 bp from pter
6,020 bases
Minus strand

Genomic View for KNCN Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for KNCN Gene

Proteins for KNCN Gene

  • Protein details for KNCN Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein Accession:
    Secondary Accessions:
    • A8MXE3

    Protein attributes for KNCN Gene

    124 amino acids
    Molecular mass:
    12832 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for KNCN Gene


neXtProt entry for KNCN Gene

Proteomics data for KNCN Gene at MOPED

Post-translational modifications for KNCN Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KNCN Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KNCN Gene

Domains & Families for KNCN Gene

Protein Domains for KNCN Gene


Suggested Antigen Peptide Sequences for KNCN Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KNCN: view

No data available for Gene Families and UniProtKB/Swiss-Prot for KNCN Gene

Function for KNCN Gene

Molecular function for KNCN Gene

UniProtKB/Swiss-Prot Function:
May play a role in stabilizing dense microtubular networks or in vesicular trafficking.

miRNA for KNCN Gene

miRTarBase miRNAs that target KNCN

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for KNCN Gene

Localization for KNCN Gene

Subcellular locations from UniProtKB/Swiss-Prot for KNCN Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for KNCN Gene COMPARTMENTS Subcellular localization image for KNCN gene
Compartment Confidence
cytoskeleton 2
plasma membrane 2

Gene Ontology (GO) - Cellular Components for KNCN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm --
GO:0015630 microtubule cytoskeleton --
GO:0016021 integral component of membrane IEA --
GO:0016324 apical plasma membrane IEA --
GO:0032437 cuticular plate IEA --
genes like me logo Genes that share ontologies with KNCN: view

Pathways & Interactions for KNCN Gene

SuperPathways for KNCN Gene

No Data Available

Interacting Proteins for KNCN Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000379607 for KNCN Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for KNCN Gene


No data available for Pathways by source and SIGNOR curated interactions for KNCN Gene

Drugs & Compounds for KNCN Gene

No Compound Related Data Available

Transcripts for KNCN Gene

mRNA/cDNA for KNCN Gene

(3) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for KNCN Gene

Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KNCN Gene

No ASD Table

Relevant External Links for KNCN Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for KNCN Gene

mRNA expression in normal human tissues for KNCN Gene

mRNA differential expression in normal tissues according to GTEx for KNCN Gene

This gene is overexpressed in Brain - Hypothalamus (x7.5), Brain - Nucleus accumbens (basal ganglia) (x7.1), and Testis (x7.0).

SOURCE GeneReport for Unigene cluster for KNCN Gene Hs.350764

genes like me logo Genes that share expression patterns with KNCN: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for KNCN Gene

Orthologs for KNCN Gene

This gene was present in the common ancestor of chordates.

Orthologs for KNCN Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia KNCN 35
  • 88.67 (n)
  • 88 (a)
  • 87 (a)
(Canis familiaris)
Mammalia KNCN 35
  • 85.33 (n)
  • 90 (a)
  • 41 (a)
(Mus musculus)
Mammalia Kncn 35
  • 83.33 (n)
  • 82 (a)
Kncn 16
Kncn 36
  • 67 (a)
(Pan troglodytes)
Mammalia KNCN 35
  • 99.01 (n)
  • 98.02 (a)
  • 80 (a)
(Rattus norvegicus)
Mammalia Kncn 35
  • 82 (n)
  • 82 (a)
(Danio rerio)
Actinopterygii KNCN 36
  • 10 (a)
Species with no ortholog for KNCN:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KNCN Gene

Gene Tree for KNCN (if available)
Gene Tree for KNCN (if available)

Paralogs for KNCN Gene

No data available for Paralogs for KNCN Gene

Variants for KNCN Gene

Structural Variations from Database of Genomic Variants (DGV) for KNCN Gene

Variant ID Type Subtype PubMed ID
nsv755 CNV Insertion 18451855

Variation tolerance for KNCN Gene

Residual Variation Intolerance Score: 74.48% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.51; 43.85% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KNCN Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for KNCN Gene

Disorders for KNCN Gene

Relevant External Links for KNCN

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with KNCN: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KNCN Gene

Publications for KNCN Gene

  1. Initial characterization of kinocilin, a protein of the hair cell kinocilium. (PMID: 15855039) Leibovici M. … Petit C. (Hear. Res. 2005) 2 67
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 67
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for KNCN Gene

Sources for KNCN Gene

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