Aliases for KMT2B Gene
Aliases for KMT2B Gene
- Lysine Methyltransferase 2B 2 3 5
- Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila) 4 2 3
- Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 4 3 4
- Lysine (K)-Specific Methyltransferase 2B 2 3
- WBP-7 3 4
- HRX2 3 4
- MLL2 3 4
- MLL4 3 4
- TRX2 3 4
- WBP7 3 4
- Histone-Lysine N-Methyltransferase MLL4 3
- Histone-Lysine N-Methyltransferase 2B 3
External Ids for KMT2B Gene
- HGNC: 15840
- Entrez Gene: 9757
- Ensembl: ENSG00000272333
- OMIM: 606834
- UniProtKB: Q9UMN6
Previous GeneCards Identifiers for KMT2B Gene
- GC19P036214
- GC19P036217
- GC19P035801
- GC19P035830
- GC19P035847
- GC19P036006
- GC19P036169
- GC19P036242
- GC19P036411
Summaries for KMT2B Gene
-
This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]
GeneCards Summary for KMT2B Gene
KMT2B (Lysine Methyltransferase 2B) is a Protein Coding gene. Diseases associated with KMT2B include Dystonia 28, Childhood-Onset and Spindle Cell Sarcoma. Among its related pathways are PKMTs methylate histone lysines and Chromatin organization. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and histone methyltransferase activity (H3-K4 specific). An important paralog of this gene is KMT2A.
UniProtKB/Swiss-Prot for KMT2B Gene
-
Histone methyltransferase. Methylates Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.
Additional gene information for KMT2B Gene
- Monarch Initiative
- Search for KMT2B at DataMed
- Search for KMT2B at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KMT2B Gene
Genomics for KMT2B Gene
GeneHancer (GH) Regulatory Elements for KMT2B Gene
Regulatory Element Products
Genomic Locations for KMT2B Gene
- chr19:35,717,995-35,738,880
- (GRCh38/hg38)
- Size:
- 20,886 bases
- Orientation:
- Plus strand
- chr19:36,208,921-36,229,779
- (GRCh37/hg19)
Genomic View for KMT2B Gene
- Cytogenetic band:
-
- 19q13.12 by Ensembl
- 19q13.12 by Entrez Gene
- 19q13.12 by HGNC


RefSeq DNA sequence for KMT2B Gene
Proteins for KMT2B Gene
-
Protein details for KMT2B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UMN6-KMT2B_HUMAN
- Recommended name:
- Histone-lysine N-methyltransferase 2B
- Protein Accession:
- Q9UMN6
- O15022
- O95836
- Q96GP2
- Q96IP3
- Q9UK25
- Q9Y668
- Q9Y669
Protein attributes for KMT2B Gene
- Size:
- 2715 amino acids
- Molecular mass:
- 293515 Da
- Quaternary structure:
-
- Component of the menin-associated histone methyltransferase complex, at least composed of KMT2B/MLL4, ASH2L, RBBP5, WDR5, DPY30, MEN1; the complex interacts with POLR2A and POLR2B via MEN1. Interacts with NFE2. Interacts with KDM6B.
Protein Expression for KMT2B Gene
Post-translational modifications for KMT2B Gene
- Ubiquitination at posLast=21962196
Other Protein References for KMT2B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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Assay Products
No data available for DME Specific Peptides for KMT2B Gene
Domains & Families for KMT2B Gene
Gene Families for KMT2B Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Enzymes
- Predicted intracellular proteins
- Transcription factors
Protein Domains for KMT2B Gene
Suggested Antigen Peptide Sequences for KMT2B Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9UMN6UniProtKB/Swiss-Prot:
KMT2B_HUMAN :- Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
- Family:
-
- Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
Function for KMT2B Gene
Molecular function for KMT2B Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
- UniProtKB/Swiss-Prot Function:
- Histone methyltransferase. Methylates Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.
Enzyme Numbers (IUBMB) for KMT2B Gene
Phenotypes From GWAS Catalog for KMT2B Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003677 | DNA binding | IEA | -- |
GO:0003700 | DNA binding transcription factor activity | NAS | 10409430 |
GO:0005515 | protein binding | IPI | 17021013 |
GO:0008168 | methyltransferase activity | IEA | -- |
GO:0008270 | zinc ion binding | IEA | -- |
Phenotypes for KMT2B Gene
- MGI mutant phenotypes for KMT2B:
-
inferred from 7 alleles
- nervous system phenotype
- normal phenotype
- homeostasis/metabolism phenotype
- cardiovascular system phenotype
- mortality/aging
- cellular phenotype
- growth/size/body region phenotype
- endocrine/exocrine gland phenotype
- reproductive system phenotype
- embryo phenotype
- liver/biliary system phenotype
- adipose tissue phenotype
- GenomeRNAi human phenotypes for KMT2B:
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miRNA for KMT2B Gene
- miRTarBase miRNAs that target KMT2B
-
- hsa-mir-7515 (MIRT536433)
- hsa-mir-302a-5p (MIRT536434)
- hsa-mir-3154 (MIRT536435)
- hsa-mir-6782-3p (MIRT536436)
- hsa-mir-519c-3p (MIRT536437)
- hsa-mir-519b-3p (MIRT536438)
- hsa-mir-519a-3p (MIRT536439)
- hsa-mir-5692a (MIRT536440)
- hsa-mir-548t-5p (MIRT536441)
- hsa-mir-548az-5p (MIRT536442)
- hsa-mir-526b-3p (MIRT536443)
- hsa-mir-519d-3p (MIRT536444)
- hsa-mir-93-5p (MIRT536445)
- hsa-mir-20a-5p (MIRT536446)
- hsa-mir-17-5p (MIRT536447)
- hsa-mir-106b-5p (MIRT536448)
- hsa-mir-106a-5p (MIRT536449)
- hsa-mir-20b-5p (MIRT536450)
- hsa-mir-153-3p (MIRT536451)
- hsa-mir-1224-3p (MIRT556671)
- hsa-mir-1294 (MIRT737173)
- hsa-mir-1914-3p (MIRT738506)
- hsa-mir-214-3p (MIRT738995)
- hsa-mir-31-5p (MIRT740494)
- hsa-mir-3184-5p (MIRT740860)
- hsa-mir-3619-5p (MIRT741718)
- hsa-mir-3689d (MIRT742469)
- hsa-mir-423-5p (MIRT743258)
- hsa-mir-4316 (MIRT743996)
- hsa-mir-4426 (MIRT744290)
- hsa-mir-4440 (MIRT744512)
- hsa-mir-4459 (MIRT744810)
- hsa-mir-4647 (MIRT746449)
- hsa-mir-4662b (MIRT746703)
- hsa-mir-4688 (MIRT747009)
- hsa-mir-4722-5p (MIRT747603)
- hsa-mir-5194 (MIRT749970)
- hsa-mir-6085 (MIRT751799)
- hsa-mir-6165 (MIRT752510)
- hsa-mir-6734-5p (MIRT754140)
- hsa-mir-6738-5p (MIRT754265)
- hsa-mir-6743-5p (MIRT754409)
- hsa-mir-6789-5p (MIRT756017)
- hsa-mir-6813-5p (MIRT756735)
- hsa-mir-6851-5p (MIRT757592)
- hsa-mir-761 (MIRT759469)
- hsa-mir-7704 (MIRT759730)
- hsa-mir-885-3p (MIRT760386)
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- Mammalian expression: PiggyBac
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- Yeast expression
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No data available for Transcription Factor Targets and HOMER Transcription for KMT2B Gene
Localization for KMT2B Gene
Subcellular locations from UniProtKB/Swiss-Prot for KMT2B Gene
- Nucleus.
- Cytosol (2)
- Nucleoplasm (2)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IDA | 17500065 |
GO:0005654 | nucleoplasm | TAS | -- |
GO:0035097 | histone methyltransferase complex | IDA,IEA | 17500065 |
No data available for Subcellular locations from COMPARTMENTS for KMT2B Gene
Pathways & Interactions for KMT2B Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Chromatin organization | ||
2 | PKMTs methylate histone lysines | ||
3 | Lysine degradation | ||
4 | Chromatin Regulation / Acetylation |
Pathways by source for KMT2B Gene
1 GeneTex pathway for KMT2B Gene
1 Cell Signaling Technology pathway for KMT2B Gene
1 BioSystems pathway for KMT2B Gene
3 Reactome pathways for KMT2B Gene
1 KEGG pathway for KMT2B Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001541 | ovarian follicle development | IEA | -- |
GO:0006351 | transcription, DNA-templated | IEA | -- |
GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
GO:0007613 | memory | IEA | -- |
GO:0009994 | oocyte differentiation | IEA | -- |
No data available for SIGNOR curated interactions for KMT2B Gene
Drugs & Compounds for KMT2B Gene
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
---|---|---|---|---|---|---|
s-adenosylmethionine |
|
29908-03-0 |
|
Transcripts for KMT2B Gene
mRNA/cDNA for KMT2B Gene
- (6) REFSEQ mRNAs :
- (436) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for KMT2B
- genomics-online: cdna clones - Search results for available KMT2B gene related products
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Expression for KMT2B Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Bone (Muscoskeletal System)
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for KMT2B Gene
NURSA nuclear receptor signaling pathways regulating expression of KMT2B Gene:
KMT2BmRNA Expression by UniProt/SwissProt for KMT2B Gene:
Q9UMN6-KMT2B_HUMANPrimer Products
-
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No data available for mRNA differential expression in normal tissues , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for KMT2B Gene
Orthologs for KMT2B Gene
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | -- 34 |
|
OneToOne | |
LOC455959 33 |
|
||||
cow (Bos Taurus) |
Mammalia | -- 34 |
|
OneToOne | |
KMT2B 33 |
|
||||
dog (Canis familiaris) |
Mammalia | -- 34 |
|
OneToOne | |
MLL4 33 |
|
||||
rat (Rattus norvegicus) |
Mammalia | LOC102550344 33 |
|
||
mouse (Mus musculus) |
Mammalia | Kmt2b 33 16 34 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToOne | |
lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | Str.7192 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | kmt2ba 34 |
|
OneToMany | |
kmt2bb 34 |
|
OneToMany | |||
fruit fly (Drosophila melanogaster) |
Insecta | trx 34 |
|
OneToMany | |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SET1 34 |
|
OneToMany | |
sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for KMT2B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for KMT2B Gene
Variants for KMT2B Gene
SNP ID | Clin | Chr 19 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1057519278 | pathogenic, Dystonia 28, childhood-onset | 35,732,955(+) | C/ | coding_sequence_variant, frameshift, genic_downstream_transcript_variant | |
rs1057519279 | pathogenic, Dystonia 28, childhood-onset | 35,720,980(+) | C/T | coding_sequence_variant, genic_upstream_transcript_variant, non_coding_transcript_variant, stop_gained | |
rs1057519280 | pathogenic, Dystonia 28, childhood-onset | 35,733,761(+) | A/G | genic_downstream_transcript_variant, splice_acceptor_variant | |
rs1057519281 | pathogenic, Dystonia 28, childhood-onset | 35,721,775(+) | C/T | coding_sequence_variant, genic_upstream_transcript_variant, non_coding_transcript_variant, stop_gained, upstream_transcript_variant | |
rs1057519282 | pathogenic, Dystonia 28, childhood-onset | 35,719,503(+) | CCCCC/CCCCCC | 5_prime_UTR_variant, coding_sequence_variant, frameshift, genic_upstream_transcript_variant, intron_variant, non_coding_transcript_variant |
Additional Variant Information for KMT2B Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KMT2B Gene
Disorders for KMT2B Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
dystonia 28, childhood-onset |
|
|
spindle cell sarcoma |
|
|
corneal staphyloma |
|
|
early-onset generalized dystonia |
|
|
kabuki syndrome 1 |
|
|
Additional Disease Information for KMT2B
No data available for UniProtKB/Swiss-Prot and Genatlas for KMT2B Gene
Publications for KMT2B Gene
- MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines. (PMID: 10637508) Huntsman DG … Caldas C (Oncogene 1999) 2 3 4 22 58
- MLL2: A new mammalian member of the trx/MLL family of genes. (PMID: 10409430) FitzGerald KT … Diaz MO (Genomics 1999) 2 3 4 58
- The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9205841) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1997) 3 4 58
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- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for KMT2B
- Cyagen custom Knockout/knockin (KOKI) mouse models for KMT2B
- VectorBuilder custom plasmid, inducible vectors for KMT2B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for KMT2B
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for KMT2B
- antibodies-online: Search results for 25 available KMT2B Antibodies ranked by validation data
- Compare Top KMT2B Antibodies
- Quality Products:
- ABIN4329263
- ABIN462281
- ABIN268620
- ABIN4329262
- ABIN203215
- ABIN203655
- ABIN2624632
- ABIN2624631
- ABIN2611792
- ABIN2887614
- ABIN4329263
- ABIN462281
- ABIN268620
- ABIN4329262
- ABIN203215
- ABIN203655
- ABIN2624632
- ABIN2624631
- ABIN2611792
- ABIN2887614
- ABIN4329263
- ABIN462281
- ABIN268620
- ABIN4329262
- ABIN203215
- ABIN203655
- ABIN2624632
- ABIN2624631
- ABIN2611792
- ABIN2887614
- ABIN4329263
- ABIN462281
- ABIN268620
- ABIN4329262
- ABIN203215
- ABIN203655
- ABIN2624632
- ABIN2624631
- ABIN2611792
- ABIN2887614
- antibodies-online: Search results for 2 available KMT2B Elisa Kits ranked by validation data
- Compare Top KMT2B Elisa Kits
- antibodies-online: Search results for 25 available KMT2B Proteins ranked by validation data
- Compare Top KMT2B Proteins
- Search GeneTex for Antibodies for KMT2B
- Search GeneTex for Proteins for KMT2B
- Search ViGene Biosciences for KMT2B
- Santa Cruz Biotechnology (SCBT) Antibodies for KMT2B
- Search Santa Cruz Biotechnology (SCBT) for KMT2B siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for KMT2B
- Horizon Cell Lines for KMT2B
- genomics-online: cdna clones - Search results for available KMT2B gene related products
- orf clones - Search results for available KMT2B gene related products
- genomics-online: gRNA clones - Search results for available KMT2B gene related products
- genomics-online: primer clones - Search results for available KMT2B gene related products
- genomics-online: shRNA clones - Search results for available KMT2B gene related products
Sources for KMT2B Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew