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Aliases for KLRAP1 Gene

Aliases for KLRAP1 Gene

  • Killer Cell Lectin-Like Receptor Subfamily A Pseudogene 1 2 3
  • Killer Cell Lectin-Like Receptor Subfamily A, Member 1, Pseudogene 3
  • Killer Cell Lectin-Like Receptor Subfamily A, Member 1 2
  • Ly-49L 3
  • KLRA# 3
  • LY49L 3
  • KLRA1 3
  • Ly49 3

External Ids for KLRAP1 Gene

Previous HGNC Symbols for KLRAP1 Gene

  • KLRA1

Previous GeneCards Identifiers for KLRAP1 Gene

  • GC12M010744
  • GC12M010746

Summaries for KLRAP1 Gene

GeneCards Summary for KLRAP1 Gene

KLRAP1 (Killer Cell Lectin-Like Receptor Subfamily A Pseudogene 1) is a Pseudogene. Among its related pathways are Immune response Role of DAP12 receptors in NK cells.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KLRAP1 Gene

Genomics for KLRAP1 Gene

Genomic Location for KLRAP1 Gene

Chromosome:
12
Start:
10,588,063 bp from pter
End:
10,599,835 bp from pter
Size:
11,773 bases
Orientation:
Minus strand

Genomic View for KLRAP1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for KLRAP1 Gene

No data available for Regulatory Elements for KLRAP1 Gene

Proteins for KLRAP1 Gene

Post-translational modifications for KLRAP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for KLRAP1 Gene

Domains & Families for KLRAP1 Gene

Suggested Antigen Peptide Sequences for KLRAP1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains and UniProtKB/Swiss-Prot for KLRAP1 Gene

Function for KLRAP1 Gene

Phenotypes for KLRAP1 Gene

genes like me logo Genes that share phenotypes with KLRAP1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for KLRAP1 Gene

Localization for KLRAP1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for KLRAP1 Gene

Pathways & Interactions for KLRAP1 Gene

genes like me logo Genes that share pathways with KLRAP1: view

Pathways by source for KLRAP1 Gene

1 GeneGo (Thomson Reuters) pathway for KLRAP1 Gene

Interacting Proteins for KLRAP1 Gene

Gene Ontology (GO) - Biological Process for KLRAP1 Gene

None

No data available for SIGNOR curated interactions for KLRAP1 Gene

Drugs & Compounds for KLRAP1 Gene

No Compound Related Data Available

Transcripts for KLRAP1 Gene

mRNA/cDNA for KLRAP1 Gene

(1) REFSEQ mRNAs :
(12) Additional mRNA sequences :
(22) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for KLRAP1 Gene

Killer cell lectin-like receptor subfamily A pseudogene 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KLRAP1 Gene

No ASD Table

Relevant External Links for KLRAP1 Gene

GeneLoc Exon Structure for
KLRAP1
ECgene alternative splicing isoforms for
KLRAP1

Expression for KLRAP1 Gene

mRNA expression in normal human tissues for KLRAP1 Gene

SOURCE GeneReport for Unigene cluster for KLRAP1 Gene Hs.159297

genes like me logo Genes that share expression patterns with KLRAP1: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for KLRAP1 Gene

Orthologs for KLRAP1 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for KLRAP1 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Klra2 16
Species with no ortholog for KLRAP1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for KLRAP1 Gene

ENSEMBL:
Gene Tree for KLRAP1 (if available)
TreeFam:
Gene Tree for KLRAP1 (if available)

Paralogs for KLRAP1 Gene

No data available for Paralogs for KLRAP1 Gene

Variants for KLRAP1 Gene

Sequence variations from dbSNP and Humsavar for KLRAP1 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs1003029 -- 10,599,210(-) TTGAA(C/T)GACTC intron-variant
rs1124164 -- 10,596,976(+) CACTG(A/G)AAATT nc-transcript-variant
rs2168749 -- 10,595,715(-) AGATC(A/C/G)TTTTT nc-transcript-variant
rs2243823 -- 10,598,977(+) GATTC(A/T)ATTGA intron-variant
rs2244387 -- 10,593,786(-) TGGAG(C/T)CCAGA nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for KLRAP1 Gene

Variant ID Type Subtype PubMed ID
nsv832329 CNV Gain 17160897
esv2745536 CNV Deletion 23290073
esv2745537 CNV Deletion 23290073
esv4222 CNV Deletion 18987735
nsv819308 CNV Loss 19587683
esv2745538 CNV Deletion 23290073
esv999821 CNV Deletion 20482838

Relevant External Links for KLRAP1 Gene

HapMap Linkage Disequilibrium report
KLRAP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for KLRAP1 Gene

Disorders for KLRAP1 Gene

Relevant External Links for KLRAP1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KLRAP1
genes like me logo Genes that share disorders with KLRAP1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KLRAP1 Gene

Publications for KLRAP1 Gene

  1. Identification of a human member of the Ly-49 multigene family. (PMID: 9645365) Westgaard I.H. … Dissen E. (Eur. J. Immunol. 1998) 2 23 67
  2. Ly49Q, an ITIM-bearing NK receptor, positively regulates osteoclast differentiation. (PMID: 20153723) Hayashi M. … Takayanagi H. (Biochem. Biophys. Res. Commun. 2010) 23 67
  3. Determining ligand specificity of Ly49 receptors. (PMID: 20033649) Lavender K.J. … Kane K.P. (Methods Mol. Biol. 2010) 23 67
  4. Ly49 cluster sequence analysis in a mouse model of diabetes: an expanded repertoire of activating receptors in the NOD genome. (PMID: 18528402) Belanger S. … Makrigiannis A.P. (Genes Immun. 2008) 23 67
  5. Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors. (PMID: 18426793) Deng L. … Mariuzza R.A. (J. Biol. Chem. 2008) 23 67

Products for KLRAP1 Gene

Sources for KLRAP1 Gene

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