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Aliases for KLKP1 Gene

Aliases for KLKP1 Gene

  • Kallikrein Pseudogene 1 2 3 5
  • Kallikrein 31 Pseudogene 2 3
  • KLK31P 3 4
  • KARMA 3 4
  • Kallikrein-Related Sequence From Prostate 3
  • Kallikrein-Related In Prostate Protein 1 4
  • Kallikrein-Related MRNA Protein 4
  • Kallikrein-Related Protein 3
  • PsiKLK1 3
  • KRSP1 3
  • YKLK1 3

External Ids for KLKP1 Gene

Previous GeneCards Identifiers for KLKP1 Gene

  • GC19U900554
  • GC19M056077
  • GC19M051385
  • GC19M047720

Summaries for KLKP1 Gene

GeneCards Summary for KLKP1 Gene

KLKP1 (Kallikrein Pseudogene 1) is a Pseudogene.

Additional gene information for KLKP1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KLKP1 Gene

Genomics for KLKP1 Gene

GeneHancer (GH) Regulatory Elements for KLKP1 Gene

Promoters and enhancers for KLKP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I050896 Enhancer 1.2 Ensembl ENCODE 550.8 -0.7 -703 1.8 HDGF PKNOX1 IRF4 ZNF766 ZNF143 FOS SP3 JUNB REST ZNF592 KLKP1 ZNF175 ZNF577 NUP62 KLK2 LINC01869 KLK15 KLK1 KLK11 POLD1
GH19I050874 Enhancer 0.9 dbSUPER 8 +19.5 19456 4.7 HDGF HDAC1 PKNOX1 ATF1 SMAD1 YBX1 TCF12 GATA2 EGR1 ZNF366 C19orf48 KLK4 POLD1 SNORD88C LINC01869 NUP62 KLKP1 KLK2 KLK3
GH19I050507 Enhancer 0.5 FANTOM5 4.9 +389.3 389254 0.2 HIC1 ZFHX2 CDC5L EGR2 ASPDH KLKP1 C19orf81 KLK4 ACP4 SHANK1 SYT3 JOSD2 LOC100506114
GH19I050887 Enhancer 0.2 dbSUPER 8.1 +8.6 8632 0.9 SNORD88C LINC01869 C19orf48 KLK4 KLK15 KLK1 SIGLEC14 SIGLEC5 RPL7P51 KLKP1
GH19I050890 Enhancer 0.9 ENCODE dbSUPER 0.4 +5.2 5245 1 HDGF EBF1 RELA FOSL1 ZNF157 NFATC1 ATF7 FOSL2 FOS IKZF2 KLK4 LINC01869 C19orf48 SNORD88C KLK15 KLK1 KLKP1 KLK2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around KLKP1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the KLKP1 gene promoter:

Genomic Locations for KLKP1 Gene

Genomic Locations for KLKP1 Gene
chr19:50,882,096-50,896,398
(GRCh38/hg38)
Size:
14,303 bases
Orientation:
Minus strand
chr19:51,385,352-51,399,654
(GRCh37/hg19)

Genomic View for KLKP1 Gene

Genes around KLKP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KLKP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KLKP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KLKP1 Gene

Proteins for KLKP1 Gene

  • Protein details for KLKP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q107X0-KRIP1_HUMAN
    Recommended name:
    Putative protein KRIP1
    Protein Accession:
    Q107X0

    Protein attributes for KLKP1 Gene

    Size:
    134 amino acids
    Molecular mass:
    14401 Da
    Quaternary structure:
    No Data Available

neXtProt entry for KLKP1 Gene

Post-translational modifications for KLKP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for KLKP1 Gene

Domains & Families for KLKP1 Gene

Protein Domains for KLKP1 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for KLKP1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KLKP1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for KLKP1 Gene

Function for KLKP1 Gene

Molecular function for KLKP1 Gene

UniProtKB/Swiss-Prot Induction:
By androgens.

Phenotypes From GWAS Catalog for KLKP1 Gene

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for KLKP1 Gene

Localization for KLKP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for KLKP1 Gene

Cytoplasm. Nucleus.

Gene Ontology (GO) - Cellular Components for KLKP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with KLKP1: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for KLKP1 Gene

Pathways & Interactions for KLKP1 Gene

SuperPathways for KLKP1 Gene

No Data Available

Interacting Proteins for KLKP1 Gene

Gene Ontology (GO) - Biological Process for KLKP1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KLKP1 Gene

Drugs & Compounds for KLKP1 Gene

No Compound Related Data Available

Transcripts for KLKP1 Gene

mRNA/cDNA for KLKP1 Gene

(6) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for KLKP1 Gene

Kallikrein pseudogene 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KLKP1 Gene

No ASD Table

Relevant External Links for KLKP1 Gene

GeneLoc Exon Structure for
KLKP1
ECgene alternative splicing isoforms for
KLKP1

Expression for KLKP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KLKP1 Gene

mRNA differential expression in normal tissues according to GTEx for KLKP1 Gene

This gene is overexpressed in Prostate (x40.6).

NURSA nuclear receptor signaling pathways regulating expression of KLKP1 Gene:

KLKP1

SOURCE GeneReport for Unigene cluster for KLKP1 Gene:

Hs.643424

mRNA Expression by UniProt/SwissProt for KLKP1 Gene:

Q107X0-KRIP1_HUMAN
Tissue specificity: Abundant expression is found in prostate, restricted to cells of epithelial origin in normal and diseased glands. Very low expression is detected in pancreas and ovary.
genes like me logo Genes that share expression patterns with KLKP1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for KLKP1 Gene

Orthologs for KLKP1 Gene

Evolution for KLKP1 Gene

ENSEMBL:
Gene Tree for KLKP1 (if available)
TreeFam:
Gene Tree for KLKP1 (if available)

No data available for Orthologs for KLKP1 Gene

Paralogs for KLKP1 Gene

No data available for Paralogs for KLKP1 Gene

Variants for KLKP1 Gene

Sequence variations from dbSNP and Humsavar for KLKP1 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000072099 -- 50,890,946(-) A/G intron_variant
rs1000085250 -- 50,896,102(-) T/C intron_variant
rs1000096457 -- 50,882,165(-) G/T non_coding_transcript_variant
rs1000263441 -- 50,893,265(-) C/G intron_variant
rs1000339947 -- 50,891,214(-) T/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for KLKP1 Gene

Variant ID Type Subtype PubMed ID
esv3644660 CNV loss 21293372
nsv1140251 OTHER inversion 24896259

Additional Variant Information for KLKP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KLKP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for KLKP1 Gene

Disorders for KLKP1 Gene

Additional Disease Information for KLKP1

No disorders were found for KLKP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KLKP1 Gene

Publications for KLKP1 Gene

  1. A novel transcript from the KLKP1 gene is androgen regulated, down-regulated during prostate cancer progression and encodes the first non-serine protease identified from the human kallikrein gene locus. (PMID: 18196551) Kaushal A … Hooper JD (The Prostate 2008) 2 3 4 22 58
  2. KLK31P is a novel androgen regulated and transcribed pseudogene of kallikreins that is expressed at lower levels in prostate cancer cells than in normal prostate cells. (PMID: 16541416) Lu W … Lin B (The Prostate 2006) 2 3 4 58
  3. Cloning of a kallikrein pseudogene. (PMID: 15498522) Yousef GM … Diamandis EP (Clinical biochemistry 2004) 2 3 58
  4. A possible mechanism behind autoimmune disorders discovered by genome-wide linkage and association analysis in celiac disease. (PMID: 23936387) Östensson M … Torinsson-Naluai Å (PloS one 2013) 3 58
  5. Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA. (PMID: 23359319) Jin G … Xu J (Neoplasia (New York, N.Y.) 2013) 3 58

Products for KLKP1 Gene

Sources for KLKP1 Gene

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