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Aliases for KLKP1 Gene

Aliases for KLKP1 Gene

  • Kallikrein Pseudogene 1 2 3
  • Kallikrein 31 Pseudogene 2 3
  • KLK31P 3 4
  • KARMA 3 4
  • Kallikrein-Related Sequence From Prostate 3
  • Kallikrein-Related In Prostate Protein 1 4
  • Kallikrein-Related MRNA Protein 4
  • Kallikrein-Related Protein 3
  • PsiKLK1 3
  • KRSP1 3
  • YKLK1 3

External Ids for KLKP1 Gene

Previous GeneCards Identifiers for KLKP1 Gene

  • GC19U900554
  • GC19M056077
  • GC19M051385
  • GC19M047720

Summaries for KLKP1 Gene

GeneCards Summary for KLKP1 Gene

KLKP1 (Kallikrein Pseudogene 1) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KLKP1 Gene

Genomics for KLKP1 Gene

Regulatory Elements for KLKP1 Gene

Genomic Location for KLKP1 Gene

Start:
50,882,096 bp from pter
End:
50,896,398 bp from pter
Size:
14,303 bases
Orientation:
Minus strand

Genomic View for KLKP1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KLKP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KLKP1 Gene

Proteins for KLKP1 Gene

  • Protein details for KLKP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q107X0-KRIP1_HUMAN
    Recommended name:
    Putative protein KRIP1
    Protein Accession:
    Q107X0
    Secondary Accessions:

    Protein attributes for KLKP1 Gene

    Size:
    134 amino acids
    Molecular mass:
    14401 Da
    Quaternary structure:
    No Data Available

neXtProt entry for KLKP1 Gene

Proteomics data for KLKP1 Gene at MOPED

Post-translational modifications for KLKP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for KLKP1 Gene

Domains for KLKP1 Gene

Gene Families for KLKP1 Gene

HGNC:
  • KLK :Kallikreins

Protein Domains for KLKP1 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for KLKP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KLKP1: view

No data available for UniProtKB/Swiss-Prot for KLKP1 Gene

Function for KLKP1 Gene

Molecular function for KLKP1 Gene

UniProtKB/Swiss-Prot Induction: By androgens.

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for KLKP1 Gene

Localization for KLKP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for KLKP1 Gene

Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KLKP1 Gene COMPARTMENTS Subcellular localization image for KLKP1 gene
Compartment Confidence
nucleus 5
extracellular 2
mitochondrion 2
plasma membrane 2
cytosol 1

Gene Ontology (GO) - Cellular Components for KLKP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with KLKP1: view

Pathways for KLKP1 Gene

SuperPathways for KLKP1 Gene

No Data Available

Interacting Proteins for KLKP1 Gene

Gene Ontology (GO) - Biological Process for KLKP1 Gene

None

No data available for Pathways by source for KLKP1 Gene

Transcripts for KLKP1 Gene

mRNA/cDNA for KLKP1 Gene

(6) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for KLKP1 Gene

Kallikrein pseudogene 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for KLKP1

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KLKP1 Gene

No ASD Table

Relevant External Links for KLKP1 Gene

GeneLoc Exon Structure for
KLKP1
ECgene alternative splicing isoforms for
KLKP1

Expression for KLKP1 Gene

mRNA expression in normal human tissues for KLKP1 Gene

mRNA differential expression in normal tissues according to GTEx for KLKP1 Gene

This gene is overexpressed in Prostate (40.6).

SOURCE GeneReport for Unigene cluster for KLKP1 Gene Hs.643424

mRNA Expression by UniProt/SwissProt for KLKP1 Gene

Q107X0-KRIP1_HUMAN
Tissue specificity: Abundant expression is found in prostate, restricted to cells of epithelial origin in normal and diseased glands. Very low expression is detected in pancreas and ovary.
genes like me logo Genes that share expressions with KLKP1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Protein expression for KLKP1 Gene

Orthologs for KLKP1 Gene

Evolution for KLKP1 Gene

ENSEMBL:
Gene Tree for KLKP1 (if available)
TreeFam:
Gene Tree for KLKP1 (if available)

No data available for Orthologs for KLKP1 Gene

Paralogs for KLKP1 Gene

No data available for Paralogs for KLKP1 Gene

Variants for KLKP1 Gene

Sequence variations from dbSNP and Humsavar for KLKP1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs198955 -- 50,887,252(-) CACAC(C/T)TCCCC intron-variant
rs198956 -- 50,887,097(-) AGTCT(C/T)TGGTT intron-variant
rs198957 -- 50,886,304(-) TGTAC(A/G)TGTGG intron-variant
rs198958 -- 50,885,622(-) CAGGA(A/T)AGGAA intron-variant
rs198959 -- 50,885,436(-) AAACA(C/G)AGACA intron-variant

Relevant External Links for KLKP1 Gene

HapMap Linkage Disequilibrium report
KLKP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for KLKP1 Gene

Disorders for KLKP1 Gene

No disorders were found for KLKP1 Gene.

No data available for UniProtKB/Swiss-Prot for KLKP1 Gene

Publications for KLKP1 Gene

  1. A novel transcript from the KLKP1 gene is androgen regulated, down- regulated during prostate cancer progression and encodes the first non-serine protease identified from the human kallikrein gene locus. (PMID: 18196551) Kaushal A. … Hooper J.D. (Prostate 2008) 2 3 4 23
  2. KLK31P is a novel androgen regulated and transcribed pseudogene of kallikreins that is expressed at lower levels in prostate cancer cells than in normal prostate cells. (PMID: 16541416) Lu W. … Lin B. (Prostate 2006) 2 3 4
  3. Cloning of a kallikrein pseudogene. (PMID: 15498522) Yousef G.M. … Diamandis E.P. (Clin. Biochem. 2004) 2 3
  4. Kallikreins on steroids: structure, function, and hormonal regulation of prostate-specific antigen and the extended kallikrein locus. (PMID: 20103546) Lawrence M.G. … Clements J.A. (Endocr. Rev. 2010) 3
  5. Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA. (PMID: 23359319) Jin G. … Xu J. (Neoplasia 2013) 3

Products for KLKP1 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate KLKP1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for KLKP1
    • Block miRNA regulation of KLKP1 using miScript Target Protectors

    Sources for KLKP1 Gene

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