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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KLK15 Gene

protein-coding   GIFtS: 57
GCID: GC19M051328

kallikrein-related peptidase 15

(Previous name: kallikrein 15 )
 Explore 12 diseases affiliated with
KLK15 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for KLK15    

Aliases
for KLK15 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Kallikrein-Related Peptidase 151 2     Kallikrein-151
ACO1 2     Kallikrein-Like Serine Protease2
HSRNASPH1 2     EC 3.4.21.-3
Prostinogen1     EC 3.4.218
ACO Protease2 3     EC 3.4.21.48
Kallikrein 151     

External Ids:    HGNC: 204531   Entrez Gene: 555542   Ensembl: ENSG000001745627   OMIM: 6106015   UniProtKB: Q9H2R53   

Export aliases for KLK15 gene to outside databases

Previous GC identifers: GC19M051957 GC19M051689 GC19M056004 GC19M056020 GC19M047663


Summaries
for KLK15 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for KLK15:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that
many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease
biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In
prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic
marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in
multiple transcript variants encoding distinct isoforms. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: KLK15_HUMAN, Q9H2R5
Function: Protease whose physiological substrate is not yet known

Gene Wiki entry for KLK15


Genomic Views
for KLK15 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KLK15 gene promoter:
         STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: KLK15 promoter sequence
   Search SABiosciences Chromatin IP Primers for KLK15

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KLK15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.41   Ensembl cytogenetic band:  19q13.33   HGNC cytogenetic band: 19q13.4

KLK15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KLK15 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M051328:  view genomic region     (about GC identifiers)

Start:
 51,328,545 bp from pter      End:
 51,334,779 bp from pter
Size:
 6,235 bases      Orientation:
 minus strand

Proteins
for KLK15 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: KLK15_HUMAN, Q9H2R5 (See protein sequence)
Recommended Name: Kallikrein-15 precursor  
Size: 256 amino acids; 28087 Da
Subcellular location: Secreted (Probable)
Secondary accessions: A0AUY8 Q15358 Q9H2R3 Q9H2R4 Q9H2R6 Q9HBG9
Alternative splicing: 4 isoforms:  Q9H2R5-1   Q9H2R5-2   Q9H2R5-3   Q9H2R5-4   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for KLK15: NX_Q9H2R5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H2R5

    • 4/8 DME Specific Peptides for KLK15 (Q9H2R5) (see all 8)
     QGIVSWG  SQPWQVA  SGGPLVC  GDSGGPL 

    KLK15 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_059979.2  NP_612630.1  NP_612631.1  

    ENSEMBL proteins: 
     ENSP00000314783   ENSP00000415136   ENSP00000301421  

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    OriGene Protein Over-expression Lysate (see all 3): KLK15
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    Novus Biologicals KLK15 Proteins
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    Uscn Proteins for KLK15

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region NAS--


    KLK15 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for KLK15

    Protein Domains /
    Families
    for KLK15 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    KLK15 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR001314 Peptidase_S1A
     IPR001254 Peptidase_S1
     IPR018114 Peptidase_S1_AS
     IPR009003 Trypsin-like_Pept_dom

    Graphical View of Domain Structure for InterPro Entry Q9H2R5

    ProtoNet protein and cluster: Q9H2R5

    2 Blocks protein families:
    IPB001254 Serine protease
    IPB001314 Chymotrypsin serine protease family (S1) signature


    UniProtKB/Swiss-Prot: KLK15_HUMAN, Q9H2R5
    Similarity: Belongs to the peptidase S1 family. Kallikrein subfamily
    Similarity: Contains 1 peptidase S1 domain


    Function
    for KLK15 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: KLK15_HUMAN, Q9H2R5
    Function: Protease whose physiological substrate is not yet known

    Enzyme Numbers (IUBMB): EC 3.4.21.42 EC 3.4.212 EC 3.4.21.-1

    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate KLK15:
    hsa-miR-224 hsa-miR-185* hsa-miR-767-3p
    SwitchGear 3'UTR luciferase reporter plasmid: KLK15 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Search LifeMap BioReagents cell lines for KLK15

    In Situ Assay
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         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLK15

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004252serine-type endopeptidase activity NAS11010966
    GO:0008236serine-type peptidase activity TAS8018728


    KLK15 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for KLK15:
     Increased gamma-H2AX phosphory  Large nuclei 


    Pathways & Interactions
    for KLK15 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Blood Coagulation Cascade
    		Blood Coagulation Cascade1.00
    		Intrinsic Prothrombin Activation Pathway0.96
    2MSP-RON Signaling
    		MSP-RON Signaling1.00

    3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for KLK15
        MSP-RON Signaling
    Blood Coagulation Cascade
    Intrinsic Prothrombin Activation Pathway


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KLK15

    1 Interacting protein for KLK15 (Q9H2R53) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HOOK2Q96ED93I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis NAS--


    KLK15 for ontologies           About GeneDecksing



    Drugs & Compounds
    for KLK15 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    KLK15 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KLK15
    4 Novoseek chemical compound relationships for KLK15 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    serine 69 18 8328387 (1), 7508789 (1), 7543009 (1), 9028629 (1) (see all 18)
    progestins 51.6 1 12915603 (1)
    steroid 26.9 2 11010966 (1), 12915603 (1)
    testosterone 21.1 1 12439720 (1)

    Search CenterWatch for drugs/clinical trials and news about KLK15 

    Transcripts
    for KLK15 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for KLK15 gene (4 alternative transcripts): 
    NM_017509.2  NM_138563.1  NM_138564.1  NM_023006.1  

    Unigene Cluster for KLK15:

    Kallikrein-related peptidase 15
    Hs.567535  [show with all ESTs]
    Unigene Representative Sequence: AF303046
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000326856(uc002ptl.3 uc002pto.3 uc010ych.2) ENST00000416184(uc002ptm.3)
    ENST00000301421(uc002ptn.3 uc010yci.2 uc010eod.3)

    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate KLK15:
    hsa-miR-224 hsa-miR-185* hsa-miR-767-3p
    SwitchGear 3'UTR luciferase reporter plasmid: KLK15 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: KLK15
    OriGene siRNA: KLK15
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KLK15
    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLK15 
    Primer
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    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KLK15
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KLK15

    Additional cDNA sequence: 

    AF303046.1 BC069480.1 BC069507.1 BC069518.1 BC126137.1 BC144045.1 BC144046.1 BC144047.1 

    3 DOTS entries:

    DT.102821249  DT.101979218  DT.100745624 

    19 AceView cDNA sequences:

    BC069518 BX280958 NM_023006 AY373373 NM_017509 NM_138564 BC069480 AY373374 
    NM_138563 CA432733 BP431267 AW205420 BP428687 AF303046 AW274270 BC069507 
    BP431386 CF139951 X75363 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for KLK15    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b
    SP1:                                                      
    SP2:                                                      
    SP3:                                                      
    SP4:        -     -                                       


    ECgene alternative splicing isoforms for KLK15

    Expression
    for KLK15 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KLK15 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAACAGAACG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See KLK15 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KLK15

    SOURCE GeneReport for Unigene cluster: Hs.567535

    UniProtKB/Swiss-Prot: KLK15_HUMAN, Q9H2R5
    Tissue specificity: Highest expression in the thyroid gland. Also expressed in the prostate, salivary, and adrenal
    glands and in the colon testis and kidney

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    In Situ
    Assay Products:     
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    Orthologs
    for KLK15 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for KLK15 gene from 2/11 species (see all 11)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    (see all 4)    		 --
    		 45(a)
    42(a)
    (see all 4)    		 1 ↔ many
    possible ortholog
    (see all 4)    		 GL343276.1(1578128-1583778)
    GL343276.1(1756111-1760844)
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc:663826
    si:ch73-103b2.36
    		 si:ch73-103b2.3
    		 46(a)
    45(a)
    		 many ↔ many
    many ↔ many
    		 16(28253006-28254288)
    16(28257799-28259131)


    ENSEMBL Gene Tree for KLK15 (if available)
    TreeFam Gene Tree for KLK15 (if available) 

    Paralogs
    for KLK15 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KLK15 gene
    KLK102  KLK12  KLK42  PRSS372  KLK112  KLK72  KLK142  KLK92  
    KLK122  KLK132  KLK62  KLK22  KLK52  PRSS12  PRSS582  PRSS32  
    KLK32  KLK82  
    18/73 SIMAP similar genes for KLK15 using alignment to 6 protein entries:     KLK15_HUMAN (see all proteins) (see all similar genes):
    KLK11    KLK8    KLK12    KLK9    KLK6    PRSS1
    KLK5    TRY8    KLK7    PRSS2    TRY6    PRSS3
    KLK14    KLK4    CELA3A    KLK1    KLK13    KLK10

    KLK15 for paralogs           About GeneDecksing



    Genomic Variants
    for KLK15 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/224 NCBI SNPs in KLK15 are shown (see all 224)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 19 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs32128081,2
    		C,F,H,--47664312(-) TGCAAA/CTGGTG 3 -- int117Minor allele frequency- C:0.05NS EA NA MN CSA WA 2016
    rs27394111,2
    		H--47664473(+) aatctC/Tacccc 3 -- int14Minor allele frequency- T:0.00NS EA 420
    rs32128071,2
    		C,F,H--47664757(-) TTGGAG/ATTGGG 3 -- int13Minor allele frequency- A:0.01NS 262
    rs621131641,2
    		C,F,--47664808(+) AGCCTA/CACCCT 3 -- int11Minor allele frequency- C:0.02MN 156
    rs104034071,2
    		C,F,H--47665048(+) TGGGAG/AACTCA 4 /L /F int1 mis1 ese310Minor allele frequency- A:0.01NS EA NA 1034
    rs104036121,2
    		H--47665080(+) GAGCAG/AATCCA 3 -- int14Minor allele frequency- A:0.00NS EA 420
    rs72471901,2
    		H--47665273(+) CGTGGG/ATAGCA 5 /P /S int1 mis1 ese34Minor allele frequency- A:0.00NS EA 418
    rs1133136711,2
    		--47665555(+) GGTCTC/GCCGAC 3 -- int12Minor allele frequency- G:0.08CSA WA 120
    rs788211001,2
    		C,--47665857(+) TTTCAG/AAACCC 3 -- int12Minor allele frequency- A:0.01MN NA 276
    rs27394161,2
    		H--47665899(+) CAAATC/ATAGGA 3 -- int14Minor allele frequency- A:0.00NS EA 420

    HapMap Linkage Disequilibrium report for KLK15 (51328545 - 51334779 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for KLK15
         2 CNVs: 50196 50197
    Human Gene Mutation Database (HGMD): KLK15

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KLK15
    DNA2.0 Custom Variant and Variant Library Synthesis for KLK15

    Disorders / Diseases
    for KLK15 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    KLK15 for disorders           About GeneDecksing

    OMIM gene information: 610601    OMIM disorders: --

    12 diseases for KLK15:    About MalaCards
    prostate cancer    prostatitis    peripheral vascular disease    bronchogenic carcinoma
    vascular disease    breast cancer    carcinoma    alzheimer's disease
    ovarian cancer    meningioma    thyroiditis    leukemia

    1 disease from the University of Copenhagen DISEASES database for KLK15:
    Bronchogenic carcinoma

    5 Novoseek disease relationships for KLK15 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    prostate cancer 52.9 3 11010966 (3)
    prostate carcinoma 35 1 11434875 (1)
    breast carcinoma 23.5 1 12439720 (1)
    breast cancer 15.4 2 12439720 (2)
    cancer 0 1 12915603 (1)

    Human Genome Epidemiology (HuGE) Navigator: KLK15 (11 documents)

    Export disorders for KLK15 gene to outside databases

    Publications
    for KLK15 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KLK15 gene, integrated from 9 sources (see all 48):
    (articles sorted by number of sources associating them with KLK15)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning of the human kallikrein 15 gene (KLK15). Up- regulation in prostate cancer. (PubMed id 11010966)1, 2, 3, 9 Yousef G.M.... Diamandis E.P. (2001)
    2. The androgen-regulated gene human kallikrein 15 (KLK15) is an independent and favourable prognostic marker for breast cancer. (PubMed id 12439720)1, 3, 9 Yousef G.M....Diamandis E.P. (2002)
    3. Proceedings of the 1st International Symposium on Kallikreins, Lausanne, Switzerland, September 1-3 , 2005. (PubMed id 16800723)1, 3 (2006)
    4. A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. (PubMed id 16800724)1, 3 Lundwall A....Yousef G.M. (2006)
    5. An unappreciated role for RNA surveillance. (PubMed id 14759258)1, 2 Hillman R.T.... Brenner S.E. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region. (PubMed id 11054574)1, 2 Gan L.... Wang K. (2000)
    8. A novel serine proteinase-like sequence from human brain. (PubMed id 8018728)1, 2 Dihanich M.E. and Spiess M. (1994)
    9. Prognostic value of the human kallikrein gene 15 expression in ovarian cancer. (PubMed id 12915603)1, 9 Yousef G.M....Diamandis E.P. (2003)
    10. Association between Prostinogen (KLK15) genetic varian ts and prostate cancer risk and aggressiveness in Australia and a meta-analysis of GWAS data. (PubMed id 22132073)1 Batra J....Spurdle A.B. (2011)

    External Searches for KLK15 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing KLK15 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55554 HGNC: 20453 AceView: KLK15 Ensembl:ENSG00000174562 euGenes: HUgn55554
    ECgene: KLK15 H-InvDB: KLK15

    Other Databases showing KLK15 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing KLK15 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KLK15 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for KLK15 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for KLK15 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for KLK15 gene:
    Search GeneIP for patents involving KLK15

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