Aliases for KLK13 Gene
External Ids for KLK13 Gene
Previous GeneCards Identifiers for KLK13 Gene
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for KLK13 Gene
KLK13 (Kallikrein Related Peptidase 13) is a Protein Coding gene. Among its related pathways are Collagen biosynthesis and modifying enzymes and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). GO annotations related to this gene include hydrolase activity and endopeptidase activity. An important paralog of this gene is KLK11.