KLK11 Gene
protein-coding GIFtS: 56
GCID: GC19M051525
|
|
kallikrein-related peptidase 11(Previous name: kallikrein 11 )
(Previous symbol: PRSS20)
| |
Aliases
for KLK11 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Kallikrein-Related Peptidase 111 2 | | Hippostasin3 | | PRSS201 2 3 5 | | Kallikrein-111 | | TLSP1 2 3 5 | | EC 3.4.21.-3 | | Kallikrein 111 2 | | Hippostasin3 | | Serine Protease 202 3 | | EC 3.4.218 | | Trypsin-Like Protease2 3 | | EC 3.4.21.48 | | HK111 | | |
Export aliases for KLK11 gene to outside databasesPrevious GC identifers: GC19M052155 GC19M051886 GC19M056201 GC19M056217 GC19M047858 |
Summaries
for KLK11 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KLK11:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests thatmany kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other diseasebiomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19.Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which aredifferentially expressed.(provided by RefSeq, Nov 2009)
UniProtKB/Swiss-Prot: KLK11_HUMAN, Q9UBX7Function: Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikreinsubstrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after argininebut not lysine residues
Gene Wiki entry for KLK11
|
Genomic Views
for KLK11 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KLK11 gene promoter:
ER-alpha ZID NF-E2 NF-E2 p45
Other transcription factors
Search SABiosciences Chromatin IP Primers for KLK11
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KLK11 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.33 Ensembl cytogenetic band: 19q13.41 HGNC cytogenetic band: 19q13.33KLK11 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M051525: view genomic region
(about GC identifiers)
Start:
|
51,525,487 bp from pter |
End:
|
51,531,290 bp from pter |
Size:
|
5,804 bases |
Orientation:
|
minus strand |
|
Proteins
for KLK11 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KLK11_HUMAN, Q9UBX7 (See
protein sequence)Recommended Name: Kallikrein-11 precursor Size: 282 amino acids; 31059 Da
Subcellular location: Isoform 1: Secreted
Subcellular location: Isoform 2: Golgi apparatus
Secondary accessions: O75837 Q0WXX5 Q8IXD7 Q9NS65Alternative splicing: 4 isoforms: Q9UBX7-2 Q9UBX7-1 Q9UBX7-3 Q9UBX7-4 (Localized in the prostate secretory epithelium)Explore the universe of human proteins at neXtProt for KLK11: NX_Q9UBX7
Post-translational modifications:
About 40% of KLK11 is inactivated by internal cleavage after Arg-188. This proteolytic inactivation may be effected byplasminogen1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UBX7
4/7 DME Specific Peptides for KLK11 (Q9UBX7) (see all 7)
KLK11 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001129504.1 NP_001161077.1 NP_006844.1 NP_659196.1
ENSEMBL proteins: ENSP00000324414 ENSP00000375680 ENSP00000324269 ENSP00000413958
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
IEA | -- | | GO:0005794 | Golgi apparatus |
IEA | -- |
KLK11 for ontologies About GeneDecksing
KLK11 Antibody Products:
Assay Products for KLK11: |
Protein
Domains /
Families
for KLK11 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KLK11 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UBX7ProtoNet protein and cluster: Q9UBX7 2 Blocks protein families: IPB001254 Serine protease IPB001314 Chymotrypsin serine protease family (S1) signature
UniProtKB/Swiss-Prot: KLK11_HUMAN, Q9UBX7Similarity: Belongs to the peptidase S1 family. Kallikrein subfamilySimilarity: Contains 1 peptidase S1 domain |
Function
for KLK11 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KLK11_HUMAN, Q9UBX7Function: Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikreinsubstrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after argininebut not lysine residuesEnzyme Numbers (IUBMB): EC 3.4.21.42 EC 3.4.212 EC 3.4.21.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KLK11 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KLK11 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): KLK11 (NM_001136032) | |  | Sino Biological Human cDNA Clone for KLK11 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KLK11 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLK11 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLK11 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004252 | serine-type endopeptidase activity |
IEA | -- | | GO:0008236 | serine-type peptidase activity |
TAS | 9765601 |
KLK11 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Klk11tm1Lex for KLK11
1 MGI phenotypic allele  for Klk11 (no phenotypes)
KLK11 for phenotypes About GeneDecksing
|
Pathways & Interactions
for KLK11 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Blood Coagulation Cascade | | | 2 | MSP-RON Signaling | |
3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for KLK11
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KLK11
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006508 | proteolysis |
IEA | -- |
KLK11 for ontologies About GeneDecksing
|
Drugs & Compounds
for KLK11 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
KLK11 for compounds About GeneDecksing
 Browse Tocris compounds for KLK11
10/27 Novoseek chemical compound relationships for KLK11 gene (see all 27) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| serine |
86 |
205 |
11341363 (4), 15781388 (3), 16982065 (3), 10662548 (3) (see all 99) |
| babim |
76.7 |
1 |
8437115 (1) |
| tlck |
76.6 |
10 |
15507121 (1), 16768813 (1), 9204960 (1), 9532790 (1) (see all 8) |
| leupeptin |
74.2 |
4 |
14500256 (1), 9204960 (1), 18445191 (1), 9301143 (1) |
| benzamidine |
73.9 |
1 |
16768813 (1) |
| chymostatin |
68.4 |
1 |
9301143 (1) |
| tpck |
63.6 |
1 |
15507121 (1) |
| n-tosyl-l-phenylalanine chloromethyl ketone |
61.5 |
1 |
15507121 (1) |
| aprotinin |
54.9 |
2 |
14500256 (1), 10777616 (1) |
| amidines |
52.2 |
1 |
10715155 (1) |
Search CenterWatch for drugs/clinical trials and news about KLK11
|
Transcripts
for KLK11 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KLK11 gene (4 alternative transcripts): NM_001136032.2 NM_001167605.1 NM_006853.2 NM_144947.1 Unigene Cluster for KLK11: Kallikrein-related peptidase 11 Hs.57771 [show with all ESTs]Unigene Representative Sequence: AK3082074 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000319756(uc002pvd.1 uc002pve.1) ENST00000391804(uc002pvb.2)
ENST00000319720(uc002pvf.1) ENST00000453757(uc002pvc.4 uc010eom.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KLK11 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KLK11 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): KLK11 (NM_001136032) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KLK11 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLK11 |
Additional cDNA sequence: AB012917.1 AB013730.1 AB041036.1 AB078780.1 AB259014.1 AB261897.1 AK308207.1 AY359014.1 BC015551.2 BC022068.1 7 DOTS entries: DT.100752394 DT.312084 DT.121428403 DT.95209682 DT.100752393 DT.97835843 DT.121428407 24/66 AceView cDNA sequences (see all 66): BM982377 NM_006853 CA437458 AB013730 BU684799 NM_144947 AA402028 BU676834 AA435952 AA477282 AW969530 AY359014 AB041036 BM837078 BC015551 BG697071 AB012917 AI659265 BE646241 BI818697 BG720793 BM559617 AB078780 AA503821
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for KLK11 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | · | 9c |
|---|
|
| SP1: | | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for KLK11
|
Expression
for KLK11 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KLK11 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGTGTGCCA
About this image
See KLK11 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KLK11
SOURCE GeneReport for Unigene cluster: Hs.57771
UniProtKB/Swiss-Prot: KLK11_HUMAN, Q9UBX7Tissue specificity: Expressed in brain, skin and prostate. Isoform 1 is expressed preferentially in brain. Isoform 2 isexpressed in prostate. Present in seminal plasma at concentrations ranging from 2 to 37 microg/mL (at protein level)
SABiosciences Custom PCR Arrays for KLK11
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KLK11
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KLK11 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KLK11 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KLK11 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLK11 |
Orthologs
for KLK11 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for KLK11 gene from 2/9 species (see all 9) About this table
ENSEMBL Gene Tree for KLK11 (if available)
TreeFam Gene Tree for KLK11 (if available) |
Paralogs
for KLK11 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KLK11 gene
- KLK102 KLK12 KLK42 PRSS372 KLK72 KLK142 KLK92 KLK132
- KLK62 KLK122 KLK22 KLK152 KLK52 PRSS12 PRSS582 PRSS32
- KLK32 KLK82
18/86 SIMAP similar genes for KLK11 using alignment to 5 protein entries: KLK11_HUMAN (see all proteins)
(see all similar genes):KLK9 KLK5 KLK8 KLK6 KLK15 KLK13
KLK14 KLK1 KLK7 KLK4 PRSS3 KLK12
APS KLK10 KLK2 TRY6 CTRL PRSS1
KLK11 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for KLK11
PGOHUM00000262495
|
Genomic Variants
for KLK11 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KLK11 (51525487 - 51531290 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for KLK11: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KLK11 |
|
Disorders
/ Diseases
for KLK11 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KLK11 for disorders About GeneDecksing
OMIM gene information: 604434
OMIM disorders: --
20/33  diseases for KLK11 (see all 33): About MalaCardsdna topoisomerase i duchenne muscular dystrophy proliferative vitreoretinopathy scimitar syndrome
muscular dystrophy retinal detachment vitreoretinopathy malignant mesothelioma
epithelial ovarian cancer periodontal disease periodontitis thrombosis
prostate cancer alzheimer's disease rheumatoid arthritis prostate cancer, progression of
ovarian cancer influenza prostatitis psoriasis
10/17 Novoseek disease relationships for KLK11 gene (see all 17) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| airways disease |
35.3 |
4 |
11326745 (1), 14500256 (1), 9565616 (1), 16336275 (1) |
| prostate cancer |
26.9 |
20 |
11550212 (4), 15893744 (3), 19242826 (2), 16800741 (2) (see all 9) |
| periodontal diseases |
21.6 |
1 |
7553388 (1) |
| metastasis |
1.28 |
5 |
11311057 (1), 16420035 (1), 11745444 (1), 15358180 (1) (see all 5) |
| cancer |
1.14 |
10 |
17487371 (2), 15781388 (1), 19242826 (1), 12736044 (1) (see all 7) |
| carcinoma squamous cell |
0 |
1 |
15558215 (1) |
| virus infection |
0 |
1 |
16325937 (1) |
| asthma |
0 |
2 |
11325588 (1), 11341363 (1) |
| inflammation |
0 |
2 |
1338289 (1), 9568894 (1) |
| breast cancer |
0 |
6 |
17487371 (2), 10373425 (1) |
Genetic Association Database (GAD): KLK11
Human Genome Epidemiology (HuGE) Navigator: KLK11 (1 document)
Export disorders for KLK11 gene to outside databases
|
Publications
for KLK11 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KLK11 gene, integrated from 9 sources (see all 237):
(articles sorted by number of sources associating them with KLK11) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Genomic organization, mapping, tissue expression, and hormonal regulation of trypsin-like serine protease (TLSP PRSS20), a new member of the human kallikrein gene family. (PubMed id 10662548)1, 2, 3, 9 Yousef G.M....Diamandis E.P. (2000)
- cDNA cloning and expression of a novel serine protease, TLSP. (PubMed id 9765601)1, 2, 3 Yoshida S.... Shiosaka S. (1998)
- A novel isoform of a kallikrein-like protease, TLSP/hippostasin, (PRSS20), is expressed in the human brain and prostate. (PubMed id 10872828)1, 2, 9 Mitsui S.... Yamaguchi N. (2000)
- Molecular cloning and expression of a variant form of hippostasin/KLK11 in prostate. (PubMed id 12539228)1, 2, 9 Nakamura T.... Yamaguchi N. (2003)
- Multiple promoters regulate tissue-specific alternative splicing of the human kallikrein gene, KLK11/hippostasin. (PubMed id 16911518)1, 2, 9 Mitsui S.... Yamaguchi N. (2006)
- Favorable prognostic value of tissue human kallikrein 11 (hK11) in patients with ovarian carcinoma. (PubMed id 12845660)1, 4, 9 Borgono C.A....Katsaros D. (2003)
- Proceedings of the 1st International Symposium on Kallikreins, Lausanne, Switzerland, September 1-3 , 2005. (PubMed id 16800723)1, 3 (2006)
- A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. (PubMed id 16800724)1, 3 Lundwall A....Yousef G.M. (2006)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
|
External Searches for KLK11 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KLK11 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KLK11 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KLK11 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for KLK11 gene:
Search GeneIP for patents involving KLK11
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KLK11 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KLK11 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KLK11 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KLK11 | | | OriGene Protein Over-expression Lysate for KLK11 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KLK11 | | OriGene 3'-UTR Clone for KLK11 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KLK11 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KLK11 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for KLK11 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KLK11 | | OriGene Custom Protein Services for KLK11 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KLK11 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KLK11 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KLK11 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KLK11 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KLK11 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KLK11 |
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| | | | Search Tocris compounds for KLK11 |
| |  |  |  |  | | | | | | Recombinant Protein for KLK11 |
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 | | | KLK11 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLK11 |
|  |  |  | | | | ThermoFisher Antibodies for KLK11 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLK11 |
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