External Ids for KLHL9 Gene
Previous GeneCards Identifiers for KLHL9 Gene
GeneCards Summary for KLHL9 Gene
KLHL9 (Kelch Like Family Member 9) is a Protein Coding gene. Diseases associated with KLHL9 include klhl9-related childhood-onset distal myopathy and malignant melanoma, somatic. Among its related pathways are Immune System and Antigen processing- Ubiquitination and Proteasome degradation. GO annotations related to this gene include ubiquitin-protein transferase activity. An important paralog of this gene is KLHL36.
UniProtKB/Swiss-Prot for KLHL9 Gene
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.